Pyridines and derivatives
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- (1)
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Filtered Search Results
Medchemexpress LLC L-5-Hydroxytryptophan | 4350-09-8 | 99.99% | 25 G
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L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and dietary supplement, is used as an antidepressant, appetite suppressant, and sleep aid. It serves as the immediate precursor of the neurotransmitter serotonin and acts as a reserpine antagonist. It is also utilized in the treatment of fibromyalgia, myoclonus, migraine, and cerebellar ataxia.
- Endogenous metabolite
- Naturally occurring amino acid
- Dietary supplement
- Precursor of neurotransmitter serotonin
- Reserpine antagonist
- Used for research purposes only; not sold to patients
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Monocrotaline | 315-22-0 | 325.36 | 1 ML
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Monocrotaline is an 11-membered macrocyclic pyrrolizidine alkaloid. It demonstrates inhibitory effects on OCT-1 and OCT-2 with IC50 values of 36.8 μM and 1.8 mM, respectively. This compound exhibits antitumor activity and is cytotoxic to hepatocellular carcinoma cells. Monocrotaline is also utilized to induce pulmonary hypertension models in rodents.
- An 11-membered macrocyclic pyrrolizidine alkaloid.
- Inhibits OCT-1 (IC50: 36.8 μM) and OCT-2 (IC50: 1.8 mM).
- Possesses antitumor activity and is cytotoxic to hepatocellular carcinoma cells.
- Used to induce a model of pulmonary hypertension in rodents.
- Available with a purity of 99.96%.
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Medchemexpress LLC Sulfo-Cy3 NHS ester | 146368-16-3 | >95.0% | 25 MG
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Cy3-SE is a sulfonated cyanine dye-derived fluorescent labeling reagent with an excitation wavelength of approximately 515 nm and an emission wavelength of approximately 568 nm. It can interact with the π-π stacking of biomolecules (e.g., nucleoside monophosphates, proteins), inhibiting the photoisomerization process and increasing the fluorescence quantum yield and lifetime.
- Sulfonated cyanine dye-derived fluorescent labeling reagent.
- Excitation wavelength of about 515 nm and emission wavelength of about 568 nm.
- Interacts with π-π stacking of biomolecules (e.g., nucleoside monophosphates, proteins).
- Inhibits photoisomerization process.
- Increases fluorescence quantum yield and lifetime.
- Better enhancement effect on purines (dAMP, dGMP) than on pyrimidines (dCMP, dTMP) in the presence of nucleoside monophosphates (dNMPs).
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Medchemexpress LLC Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-, (3β,5β)- | 27127-79-3 | 858.96 | 1 MG
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Thevetin B (compound 1) is a betalain isolated from *Thevetia peruviana*.
- Purity: 98.71%
- Formula: C42H66O18
- Appearance: Solid
- Color: White to off-white
- Structure classification: Steroids, Cardiacglycosides
- Initial source: Plants, Apocynaceae, *Thevetia peruviana* (Pers.) K. Schum.
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Medchemexpress LLC δ-Cadinene | 483-76-1 | 204.35 | 100 MG
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δ-Cadinene is a sesquiterpene found in essential oils with significant biological activities. It demonstrates antiproliferative and pro-apoptotic effects on human ovarian cancer (OVCAR-3) cells, and also possesses trichomonacidal, antimicrobial, antifungal, and anticancer properties.
- Possesses trichomonacidal properties.
- Shows antimicrobial and antifungal activity.
- Exhibits anticancer effects.
- Inhibits OVCAR-3 cell growth in a concentration-dependent manner.
- Induces both early and late apoptosis in OVCAR-3 cells.
- Leads to sub-G1-phase growth arrest in OVCAR-3 cells.
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Medchemexpress LLC Sb 525334 | 356559-20-1 | 100.0% | 500 MG
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A potent, selective inhibitor of the transforming growth factor β type I receptor (ALK5) with nanomolar biochemical potency. Supplied as high-purity solid and DMSO solution formats for research use; consult the SDS for handling and safety guidance.
- Potent and selective ALK5 inhibitor with IC50 of 14.3 nM.
- High purity suitable for research applications.
- Available as solid and 10 mM DMSO solution formats, including 500 mg solid packs.
- Molecular weight 343.42 g/mol and formula C21H21N5.
- Stable when stored at recommended temperatures for long-term storage.
- SDS available with handling, personal protective equipment, and first-aid instructions.
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Aobchem AOBCHEM
5001079683 METHYL 2- 1-METHYL-1H-PYRAZOL-
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Medchemexpress LLC Ly2794193 | 2173037-97-1 | >98.0% | 1 ML
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LY2794193 is a potent and selective metabotropic glutamate receptor 3 (mGlu3) agonist supplied as a ready-to-use stock solution for research applications.
- Potent and selective mGlu3 receptor agonist (hmGlu3 Ki = 0.927 nM; EC50 = 0.47 nM).
- Provided as a 10 mM solution, 1 mL, suitable for preparing working stocks.
- High reported purity: ≥98%.
- Molecular formula C16H18N2O6; molecular weight ~334.32 g·mol⁻¹.
- Soluble in DMSO; stock solutions commonly prepared in DMSO for in vitro assays.
- Intended for research use in pharmacology and receptor characterization studies.
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Medchemexpress LLC Flonicamid | 158062-67-0 | 98.0% | 100 MG
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Flonicamid is an analytical standard of the insecticide flonicamid supplied as a 100 MG solid for research and analytical applications. It has molecular formula C9H6F3N3O, molecular weight 229.16 g/mol, CAS 158062-67-0, and a stated purity of 98.0%. The material is intended for analytical and laboratory use and should be stored according to the certificate of analysis.
- Analytical standard for pesticide residue and insecticide research.
- Stated purity 98.0% for reliable analytical performance.
- Solid form; store under conditions specified in the certificate of analysis.
- Molecular weight 229.16 g/mol; formula C9H6F3N3O.
- Packaged as a 100 MG unit for laboratory use.
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Medchemexpress LLC 1,2-dipalmitoyl-sn-glycero-3-phosphoglycerol sodium | 200880-41-7 | MFCD00070068 | 98.0% | 744.95 g/mol | C38H74NaO10P | 1G
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DPPG (1,2-dipalmitoyl-sn-glycero-3-phosphoglycerol sodium) is an anionic phospholipid used to prepare liposomes, micelles, and artificial membranes for membrane biophysics and biochemical research. Supplied as the sodium salt in a white to off-white solid form, it is commonly used to model lipid bilayers and investigate lipid-protein interactions.
- Supports formation of liposomes and bilayers for membrane modeling
- Useful for studies of lipid-protein interactions
- Anionic phospholipid with sodium counterion for improved solubility
- High purity suitable for research applications
- White to off-white solid compatible with common organic solvents
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Medchemexpress LLC Milvexian | 1802425-99-5 | 99.9% | 626.44 | C28H23Cl2F2N9O2 | 100MG
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Milvexian is an oral small-molecule factor XIa inhibitor provided for laboratory research into anticoagulation and thrombosis. It is supplied as a high-purity research-grade sample intended for in vitro and analytical studies. Not for human or clinical use.
- Oral factor XIa inhibitor for anticoagulation research.
- High purity suitable for analytical and in vitro studies.
- Molecular weight 626.44 g/mol and formula C28H23Cl2F2N9O2.
- CAS number 1802425-99-5 for unambiguous identification.
- Packaged as a 100 mg research quantity.
- Intended for research use only; not for clinical or human use.
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Medchemexpress LLC 1-((5-chloropyridin-3-yl)methyl)-8-(3-methylmorpholino)-2-(trifluoromethyl)-pyrimido[1,2-a]pyrimidinone | 1523406-39-4 | MFCD28411361 | 99.7% | 443.85 g·mol⁻1 | C19H21ClF3N5O2 | 10MM 1ML
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SAR405 is a selective, ATP-competitive inhibitor of Vps34 (class III PI3K) commonly used to study autophagy and vesicular trafficking in cellular and biochemical assays. It demonstrates potent target engagement and is supplied in a concentrated format for laboratory use.
- Selective Vps34 inhibition with subnanomolar potency.
- Reported IC50 ≈ 1.2 nM and Kd ≈ 1.5 nM.
- High purity suitable for biochemical and cell-based assays.
- Supplied as a concentrated solution for straightforward dosing.
- Suitable for autophagy and PI3K class III pathway research.
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Medchemexpress LLC (+)-Syringaresinol | 21453-69-0 | 98.7% | 418.44 g/mol | C22H26O8 | 1MG
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(+)-Syringaresinol is a lignan research compound that inhibits the Nuclear Factor of Activated T cells (NFAT) transcription factor, reported with an IC50 of 329.4 μM. It is provided as a high-purity material intended for in vitro research applications, including studies of lymphocytic leukemia and related cellular assays.
- Inhibits NFAT transcription factor (IC50 329.4 μM).
- Suitable for research of lymphocytic leukemia and related cellular studies.
- High purity, 98.69%.
- Molecular weight 418.44 g/mol; molecular formula C22H26O8.
- Available in small research quantities (1 mg, 5 mg; larger sizes available by quote).
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Medchemexpress LLC 2,2-diphenyl-1-picrylhydrazyl | 1898-66-4 | 98.8% | 394.32 | 25 MG
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2,2-diphenyl-1-picrylhydrazyl | 1898-66-4 | 98.8% | 394.32 | 25 MG
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Medchemexpress LLC Bz-rA phosphoramidite | 104992-55-4 | 988.19 | 1 G
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Bz-rA Phosphoramidite is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis. It is a 2'-O-protected ribonucleoside phosphoramidite.
- Can be used in the synthesis of 2'-O-guanidinopropyl-modified nucleoside phosphoramidites.
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