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Aromatic organic compounds consist of an aromatic six-membered ring containing one nitrogen atom and five carbon atoms; includes compounds derived from pyridines.
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Ercalcidiol (CAS 21343-40-8) is a metabolite targeting vitamin D receptor (VDR)-like receptors It is involved in modulating mineral homeostasis by participating in the physiological regulation of calcium and phosphorus balance Ercalcidiol exerts its biological activity primarily through binding to VDR-related receptors In isolated perfused rat kidney experimental models Ercalcidiol is metabolized into several di- and tri-hydroxylated vitamin D2 derivatives supporting studies of vitamin D2 metabolism pathways Based on these pharmacological properties Ercalcidiol holds research potential for assessing vitamin D nutritional status and investigating vitamin D2 metabolism
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Ercalcitriol (60133-18-8) is a small-molecule agonist targeting the vitamin D receptor (VDR) It is designed to modulate VDR-mediated pathways thereby regulating calcium and phosphorus metabolism Ercalcitriol exerts its biological activity primarily through binding to VDR and initiating transcriptional regulation processes In preclinical studies Ercalcitriol demonstrates activity in the regulation of calcium homeostasis and bone mineralization Based on these pharmacological properties Ercalcitriol holds research potential in the investigation of VDR signaling calcium metabolism bone mineralization and potential therapeutic effects in models of rickets and related bone metabolism disorders
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