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Filtered Search Results
eMolecules Ambeed Ritonavir 250mg 570569802 A547820 0 000 155213-67-5 MFCD00927142 720 950 C37H48N6O5S2
Ambeed Ritonavir 250mg 570569802 A547820 0 000 155213-67-5 MFCD00927142 720 950 C37H48N6O5S2
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Apexbio Technology LLC BAY 61-3606 732983-37-8 10mg
BAY 61-3606 (CAS 732983-37-8) is a selective orally bioavailable inhibitor of spleen tyrosine kinase (SYK) displaying an IC50 of 10 nM and a Ki of 7 5 nM for SYK by competitively binding ATP This compound shows minimal activity against other tyrosine kinases such as Src Fyn Lyn Btk and Itk at concentrations up to 4 7 M BAY 61-3606 suppresses Fc RI-mediated degranulation and mediator release in mast cells and basophils as well as Fc R-driven responses in macrophages and neutrophils In preclinical models BAY 61-3606 attenuates inflammatory cell functions and reduces allergic and asthmatic responses supporting its utility in investigating SYK-mediated signaling and inflammation
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Medchemexpress LLC M-PEG2-MS | 60696-83-5 | C6H14O5S | 250 MG
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m-PEG2-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PROTACs contain two different ligands connected by a linker.
- One ligand is for an E3 ubiquitin ligase.
- The other ligand is for the target protein.
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Medchemexpress LLC 5-phenylvaleric acid | 2270-20-4 | MFCD00004416 | 98.1% | 178.23 g/mol | C11H14O2 | 5 MG
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5-Phenylvaleric acid (5-phenylpentanoic acid, CAS 2270-20-4) is a phenyl-substituted valeric acid found as an endogenous metabolite produced by gut microbiota during flavan-3-ol metabolism. It is used as an analytical standard and as a chemical building block in synthesis, and is commonly employed in biomarker and analytical studies. Molecular formula: C11H14O2; molecular weight: 178.23 g/mol.
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Medchemexpress LLC Ethyl acetylglycinate | 1906-82-7 | MFCD00009173 | 98.2% | 145.16 g/mol | C6H11NO3 | 100 G
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Ethyl acetylglycinate is the ethyl ester of N-acetylglycine, an amino acid derivative used as a building block and reagent in synthetic chemistry and biochemical research. It is supplied as a solid with high purity and is suitable for use as an intermediate or for derivatization studies. Molecular formula C6H11NO3; molecular weight 145.16 g/mol.
- High purity suitable for research applications.
- Solid form simplifies handling and storage.
- Useful as a synthetic building block and intermediate.
- Stable under recommended storage conditions.
- Available in multiple pack sizes for scalability.
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eMolecules 287714-35-6 | Methyl 2-chloropyrimidine-5-carboxylate | Oakwood Chemical | MFCD08690330 | 172.570 | C6H5ClN2O2 | 98.000 | COC(=O)c1cnc(Cl)nc1 | 250mg | 853685150
Methyl 2-chloropyrimidine-5-carboxylate | Oakwood Chemical | 287714-35-6 | MFCD08690330 | 172.570 | C6H5ClN2O2 | 98.000 | COC(=O)c1cnc(Cl)nc1 | 250mg | 853685150
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Medchemexpress LLC Isoquinoline, 5-(1-piperazinyl)-, hydrochloride (1:1) | 209733-17-5 | 99.6% | 249.74 | 250 MG
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This product is described as a yellow to orange solid. It has been tested and complies with the given specifications.
- Suitable for storage at 4°C, sealed, and away from moisture.
- In solvent, store at -80°C for 6 months or -20°C for 1 month, sealed and away from moisture.
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Medchemexpress LLC NSC 135130 | 24164-06-5 | 97.1% | 245.32 | 250 MG
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NSC 135130 (compound 11a) is a BOC-protected ADC linker that can be linked to tubulin-targeting inhibitors. It can be used to synthesize drug conjugates.
- BOC-protected ADC linker
- Links to tubulin-targeting inhibitors
- Used to synthesize drug conjugates
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Medchemexpress LLC 12-Ethyl-9-hydroxycamptothecin | 119577-28-5 | 392.40 | 5 MG
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12-Ethyl-9-hydroxycamptothecin is a derivative of Camptothecin, an alkaloid and a DNA topoisomerase I (Topo I) inhibitor. This compound is used in various research applications.
- Purity: 99.89%
- Appearance: Solid
- Color: White to off-white
- Formula: C22H20N2O5
- Structure classification: Alkaloids, phenols
- Initial source: Plants other families
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light)
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eMolecules 1912399-75-7 | Omilancor | Ambeed528.576 | C30H24N8O2 | 98.000 | O=C(N1CCN(CC1)C(=O)c1cccc(n1)-c1nc2ccccc2[nH]1)c1cccc(n1)-c1nc2ccccc2[nH]1 | 250mg | 837386387
Omilancor | Ambeed | 1912399-75-7528.576 | C30H24N8O2 | 98.000 | O=C(N1CCN(CC1)C(=O)c1cccc(n1)-c1nc2ccccc2[nH]1)c1cccc(n1)-c1nc2ccccc2[nH]1 | 250mg | 837386387
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eMolecules 1323919-64-7 | 1-Methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1h-pyrazol-1-yl)piperidine | Combi-Blocks, Inc. | MFCD21337767 | 291.200 | C15H26BN3O2 | 95.000 | CN1CCC(CC1)n1cc(cn1)B1OC(C)(C)C(C)(C)O1 | 250mg | 603145820
1-Methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1h-pyrazol-1-yl)piperidine | Combi-Blocks, Inc. | 1323919-64-7 | MFCD21337767 | 291.200 | C15H26BN3O2 | 95.000 | CN1CCC(CC1)n1cc(cn1)B1OC(C)(C)C(C)(C)O1 | 250mg | 603145820
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Apexbio Technology LLC Clinafloxacin CI96 AM1091 105956-97-6 250mg
Clinafloxacin CI96 AM1091 (CAS 105956-97-6) is a small-molecule inhibitor targeting bacterial DNA gyrase and topoisomerase IV It is designed to inhibit these type II topoisomerases thereby disrupting bacterial DNA replication and transcription Clinafloxacin CI96 AM1091 exerts its biological activity primarily through dual inhibition of DNA gyrase and topoisomerase IV In enzymatic assays against Staphylococcus aureus clinafloxacin demonstrates inhibitory activity with IC50 values of 0 92 g/mL for DNA gyrase and 1 62 g/mL for topoisomerase IV Based on these pharmacological properties clinafloxacin CI96 AM1091 holds research potential in bacteriology studies of bacterial resistance mechanisms and evaluation of drug-resistant bacterial strains
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Medchemexpress LLC Succinylsulfathiazole | 116-43-8 | MFCD00022437 | 99.2% | 250 MG
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Succinylsulfathiazole is a long-acting, orally active sulfonamide antibiotic with localized gut-specific antibacterial activity. It inhibits bacterial folate synthesis, leading to reduced coliform counts, suppressed intestinal bacterial growth, and depletion of gut folate-producing bacteria. Beyond its antibacterial role, it modulates hepatic mTOR signaling, diminishes cecal fermentation, and alters folate and nitrogen excretion. This compound can also induce folate deficiency and related nutritional deficiency symptoms.
- Long-acting and orally active sulfonamide antibiotic
- Provides localized gut-specific antibacterial activity
- Inhibits bacterial folate synthesis
- Reduces coliform counts and suppresses intestinal bacterial growth
- Modulates hepatic mTOR signaling
- Diminishes cecal fermentation
- Decreases hepatic folate levels and total folate excretion
- Can induce folate deficiency
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Medchemexpress LLC Methyl cellulose | 9004-67-5 | C6H7O2(OR1)(OR2)(OR3) | 1KG
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Methyl cellulose is a non-ionic cellulose ether supplied as a white to off-white solid powder. This viscosity-grade material (nominal 4000 mPa·s) is used as a thickener, gelling agent, stabilizer, and film former in laboratory formulations and industrial processes.
- Provides reliable thickening and viscosity control.
- Exhibits thermogelation, forming gels on heating.
- Water soluble and forms clear, stable gels or films.
- Consistent physical form and appearance for reproducible formulation performance.
- Batch testing and certificate of analysis include measured viscosity (example 4466 mPa·s) for quality verification.
- Offered in practical pack sizes suitable for laboratory use.
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Medchemexpress LLC Pomalidomide 4'-PEG3-azide | 2271036-46-3 | 96.3% | 250 MG
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Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker. It can be used for the synthesis of iRucaparib-TP3 (Compound 3), a highly efficient PARP1 degrader based on Rucaparib using the PROTAC approach.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates a Pomalidomide-based cereblon ligand and a linker
- Can be used for the synthesis of efficient PARP1 degraders
- Click chemistry reagent containing an azide group
- Capable of copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups
- Capable of strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
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