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Pyrroles

Aromatic organic heterocyclic compounds that consist of a five-membered ring with four carbon atoms and one nitrogen atom that forms an amine functional group.
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1

(E)-3-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]acrolein 98.0+%, TCI America™

CAS: 93957-50-7 Molecular Formula: C20H18FNO Molecular Weight (g/mol): 307.368 MDL Number: MFCD03840863 InChI Key: DVWHSTKQJBIYCK-VMPITWQZSA-N Synonym: (E)-3-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]propenal PubChem CID: 9926593 IUPAC Name: (E)-3-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]prop-2-enal SMILES: CC(C)N1C2=CC=CC=C2C(=C1C=CC=O)C3=CC=C(C=C3)F

PubChem CID 9926593
CAS 93957-50-7
Molecular Weight (g/mol) 307.368
MDL Number MFCD03840863
SMILES CC(C)N1C2=CC=CC=C2C(=C1C=CC=O)C3=CC=C(C=C3)F
Synonym (E)-3-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]propenal
IUPAC Name (E)-3-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]prop-2-enal
InChI Key DVWHSTKQJBIYCK-VMPITWQZSA-N
Molecular Formula C20H18FNO
2

Medchemexpress LLC JNJ-18038683 | 851376-05-1 | 98.31% | 529.97 | 50 MG
SDP

JNJ-18038683 is a 5-Hydroxytryptamine Type 7 (5-HT7) receptor antagonist, with pKis of 8.19 and 8.20 for rat and human 5-HT7 in HEK293 cells. It displaces specific [3H]5-CT binding sites from rat and human 5-HT7 receptor expressed in HEK293 cells with high affinity. In vivo, it dose-dependently suppresses REM sleep.

  • High affinity for 5-HT7 receptors (rat and human)
  • Antagonizes 5-HT (100 nM)-stimulated adenylyl cyclase activity
  • Dose-dependently suppresses REM sleep
  • Maintains decreased REM sleep time with repeated administration

ENCOMPASS_PREFERRED
3

Medchemexpress LLC TLR7/8-IN-1 | 2205095-75-4 | 99.92% | 532.68 | 50 MG
SDP

TLR7/8-IN-1 is a crystalline form of a TLR7/TLR8 inhibitor extracted from patent WO2019220390, compound 2b. It is intended for research use only and can be used for the research of autoimmune disease.

  • Crystalline form of a TLR7/TLR8 inhibitor.
  • Extracted from patent WO2019220390, compound 2b.
  • Can be used for the research of autoimmune disease.
  • Available in various solid quantities ranging from 1 mg to 100 mg.
  • High purity of 99.92%.

ENCOMPASS_PREFERRED
4

Medchemexpress LLC AZ PFKFB3 26 | 1704740-52-2 | MFCD30742931 | 99.2% | 402.49 g·mol-1 | C24H26N4O2 | 50 MG
SDP

AZ PFKFB3 26 is a research-grade small-molecule inhibitor of PFKFB3 (CAS 1704740-52-2) supplied as a powder for in vitro and preclinical studies. The compound has formula C24H26N4O2 and a molecular weight of 402.49 g·mol-1. Analytical data and handling information are provided to support experimental use.

  • Documented purity available (COA shows ~99.2%).
  • Suitable for in vitro studies; soluble in DMSO at ~5 mg/mL.
  • Analytical data provided: COA, H NMR, LCMS, and SDS.
  • Storage conditions specified for powder and solutions to preserve stability.
  • Available in multiple research sizes, including 50 mg.

ENCOMPASS_PREFERRED
5

Medchemexpress LLC 4-aminophenyl β-D-glucopyranoside | 20818-25-1 | MFCD00067365 | 98.9% | 271.27 g/mol | C12H17NO6 | 50 MG
SDP

4-Aminophenyl β-D-glucopyranoside is a biochemical reagent used in life-science research, commonly employed as a substrate in enzymatic assays, for conjugation or derivatization, and as a synthetic building block. The solid material is characterized by analytic data and safety documentation suitable for laboratory use.

  • High purity (98.9%).
  • Chemical formula C12H17NO6.
  • Molecular weight 271.27 g/mol.
  • CAS number 20818-25-1.
  • Available in mg-scale packages for assay development.
  • Safety data sheets and technical documentation available.

ENCOMPASS_PREFERRED
6

Medchemexpress LLC Ethyl 2-amino-4-methyl-5-[(3-nitrophenyl)formamido]thiophene-3-carboxylate | 303141-21-1 | 99.7% | 50 MG
SDP

DC-S239 is a selective small-molecule inhibitor of the histone methyltransferase SET7 (SETD7) used for research applications. It is reported to inhibit SET7 with an IC50 of 4.59 μM and is supplied as a solid for laboratory use.

  • Selective SET7 inhibitor with reported IC50 of 4.59 μM.
  • High purity (99.7%).
  • Molecular weight 349.36 g/mol; formula C15H15N3O5S.
  • Solid, yellow-orange physical form suitable for handling and storage.
  • Available as a 50 mg research vial.

ENCOMPASS_PREFERRED
7

Medchemexpress LLC 3-(cyclopropylmethyl)-7-[(4-phenyl-1-piperidinyl)methyl]-8-(trifluoromethyl)-triazolo[4,3-a]pyridine | 1254980-38-5 | 98.8% | 50 MG
SDP

JNJ-46281222 is a metabotropic glutamate receptor 2 (mGlu2) selective positive allosteric modulator (PAM) used as a research reagent for in vitro pharmacology and receptor modulation studies.

  • Selective mGlu2 positive allosteric modulator with nanomolar affinity (Kd = 1.7 nM)
  • High modulatory potency (pEC50 = 7.71)
  • Molecular formula C23H25F3N4 and molecular weight 414.47 g·mol⁻¹
  • Purity approximately 98.8%
  • Solid, white to off-white appearance
  • Store powder at -20°C (up to 3 years) or 4°C (up to 2 years)
  • For research use only; not for human or clinical use

ENCOMPASS_PREFERRED
8

Medchemexpress LLC Urea, N-[4-(1-amino-5-isoquinolinyl)phenyl]-N'-[5-(1,1-dimethylethyl)-3-isoxazolyl]- | 1481641-08-0 | 98.9% | 401.46 | 50 MG
SDP

RIPK1-IN-4 is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase. It binds to a DLG-out inactive form of RIP1 with IC50s of 16 nM for RIP1 and 10 nM for ADP-Glo kinase.

  • Potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase.
  • Binds to a DLG-out inactive form of RIP1.
  • For research use only.

ENCOMPASS_PREFERRED
9

Medchemexpress LLC 3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)-indol-2-yl]-2,2-dimethylpropanoic | 136668-42-3 | 99.4% | 587.17 g/mol | C34H35ClN2O3S | 50 MG
SDP

Quiflapon is a potent and selective inhibitor of the 5-lipoxygenase-activating protein (FLAP) used as a research tool to study leukotriene biosynthesis, inflammation, and apoptosis pathways in vitro.

  • Selective FLAP inhibitor with reported IC50 ~1.6 nM.
  • Useful for studying leukotriene biosynthesis, inflammation, and apoptosis.
  • High chemical purity (≈99.4%) suitable for biochemical assays.
  • Available as solid and as 10 mM solution in DMSO for convenience.
  • Molecular weight ~587.17 g/mol; formula C34H35ClN2O3S.
  • Supplied in multiple pack sizes to support different experimental scales.

ENCOMPASS_PREFERRED
10

Medchemexpress LLC HY-111754 5mg Medchemexpress, DMX-5804 CAS:2306178-56-1 Purity:>98%
SDP

Medchemexpress, HY-111754 5mg DMX-5804 CAS:2306178-56-1 DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor, with an IC 50 of 3 nM, a pIC 50 of 8.55 for human MAP4K4, less potent on MINK1/MAP4K6 ( pIC 50 , 8.18), and TNIK/MAP4K7 ( pIC 50 , 7.96). DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

ENCOMPASS_PREFERRED
11

TARGETMOL CHEMICALS INC 2-HYDROXY ATORVASTATIN C 5MG
SDP

Also available in 1 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt which is a potent HMG-CoA reductase inhibitor (IC50 = 8 nM). purity: 97%

ENCOMPASS_PREFERRED
12

Medchemexpress LLC HY-122243 5mg Medchemexpress, IU1-47 CAS:670270-31-2 Purity:>98%
SDP

Medchemexpress, HY-122243 5mg IU1-47 CAS:670270-31-2 IU1-47 is a potent and specific USP14 inhibitor with an IC 50 of 0.6 μM. IU1-47 inhibits IsoT/USP5 with an IC 50 of 20 μM. IU1-47 induces tau elimination in cultured neurons [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

ENCOMPASS_PREFERRED
13

TARGETMOL CHEMICALS INC DEHYDROCOSTUS LACTONE 25MG
SDP

Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Dehydrocostus Lactone ((-)-Dehydrocostus lactone) shows anti-inflammatory anti-ulcer immunomodulatory and anti-tumor properties. purity: 99%

ENCOMPASS_PREFERRED
14

TARGETMOL CHEMICALS INC Atorvastatin hemicalcium salt
SDP

Also available in 1 mL, 10 mg, 25 mg, 50 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an HMG-CoA reductase inhibitor with oral activity. Atorvastatin hemicalcium salt is used to lower cholesterol. Purity 99.89%

ENCOMPASS_PREFERRED
15

TARGETMOL CHEMICALS INC Atorvastatin lactone 25MG
SDP

Also available in 1 mL, 2 mg, 5 mg, 10 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Purity 98.16%

ENCOMPASS_PREFERRED