Pyrrolidines
Medchemexpress LLC m-PEG4-Boc | 883554-11-8 | 292.37 g/mol | C14H28O6 | 250 MG
m-PEG4-Boc is a Boc-protected, cleavable polyethylene glycol linker containing four ethylene glycol units used for conjugation chemistry in ADC and PROTAC synthesis.
- Cleavable Boc-protected PEG4 linker.
- Designed for use in antibody-drug conjugate and PROTAC linker synthesis.
- Provides a short, flexible spacer of four ethylene glycol units.
- Available in multiple pack sizes, suitable for small-scale synthesis and development.
- Supplied as an in-stock research reagent with associated product documentation.
Medchemexpress LLC 30-azido-4,7,10,13,16,19,22,25,28-nonaoxatriacontanoic acid | 1670249-37-2 | MFCD29938006 | >97.0% | 511.56 | C21H41N3O11 | 250 MG
Azido-PEG9-acid is an azide-terminated polyethylene glycol (9-unit) carboxylic acid linker for bioconjugation and click chemistry. It provides an azide functional group for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and a carboxylic acid handle for further coupling.
- Azide functional group for click chemistry (CuAAC).
- Nine ethylene glycol units provide hydrophilicity and spacer function.
- Terminal carboxylic acid enables standard coupling reactions.
- Suitable for use as an ADC or PROTAC linker and other bioconjugation applications.
- Stable as a pure solid when stored at low temperature according to manufacturer guidance.
Medchemexpress LLC Boc-C1-PEG3-C4-OBn | 2381196-81-0 | 95.8% | 50 MG
Boc-C1-PEG3-C4-OBn is a linker compound that is characterized by its polyethylene glycol (PEG) composition. This product is utilized in the creation of various PROTACs, which are molecules designed with two distinct ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase, and the other targets a specific protein. PROTACs harness the ubiquitin-proteasome system within cells to achieve selective degradation of target proteins.
- This is a linker compound with a polyethylene glycol composition.
- It facilitates the synthesis of various PROTAC molecules.
- It contributes to the formation of PROTACs that can selectively degrade target proteins.
- The product has a high purity of 95.77%.
Medchemexpress LLC 4,7,10,13,16,19,22,25,28-nonaoxatriacontanoic acid, 30-azido | 1670249-37-2 | 97.7% | 511.56 | C21H41N3O11 | 25 MG
Azido-PEG9-acid is an azide-terminated polyethylene glycol (PEG) linker containing nine ethylene glycol units. It is used as a non-cleavable linker in antibody-drug conjugate synthesis and as a PEG-based PROTAC linker; the azide group enables CuAAC and SPAAC click reactions for bioconjugation.
- Used as a click chemistry reagent for CuAAC and SPAAC reactions.
- Non-cleavable PEG9 spacer increases solubility and flexibility.
- Contains a terminal carboxylic acid for conjugation to other functional groups.
- High purity suitable for bioconjugation and linker synthesis.
- Stable when stored at -20°C in pure form for extended periods.
Medchemexpress LLC Azido-PEG4-CH2-Boc | 864681-04-9 | 97.0% | 333.38 g/mol | C14H27N3O6 | 5 G
Azido-PEG4-CH2-Boc is an azide-functionalized, Boc-protected polyethylene glycol (PEG4) linker used for bioconjugation and linker synthesis. It provides an azide handle for click chemistry and a protected amine for orthogonal functionalization, making it suitable for linker installation in medicinal chemistry and chemical biology workflows.
- Provides an azide group for copper-catalyzed azide-alkyne cycloaddition
- Contains a four-unit polyethylene glycol spacer to increase solubility
- Features a boc-protected amine for orthogonal deprotection and coupling
- Suitable for antibody-drug conjugate and PROTAC linker assembly
- Available in multiple package sizes, including 5 g
Medchemexpress LLC Azido-PEG9-acid | 1670249-37-2 | 97.7% | 511.56 g/mol | C21H41N3O11 | 50 MG
Azido-PEG9-acid is an azido-functional polyethylene glycol linker containing nine ethylene glycol units, used as a hydrophilic spacer and azide handle for conjugation chemistry in small-molecule and bioconjugate synthesis. It is suitable for click chemistry, antibody-drug conjugate (ADC) linker assembly, and PROTAC construction.
- Azido functional group for efficient click chemistry conjugation.
- Nine-unit PEG spacer to increase solubility and reduce steric hindrance.
- Non-cleavable linker suitable for ADC and PROTAC synthesis.
- Molecular weight 511.56 g/mol and defined chemical formula.
- Available in small-mass research quantities for synthetic applications.
Medchemexpress LLC Azido-PEG9-acid | 1670249-37-2 | 97.7% | 511.56 | C21H41N3O11 | 100 MG
Azido-PEG9-acid is an azide-functional polyethylene glycol linker containing nine ethylene glycol units, intended for bioconjugation and synthetic applications. It serves as a click-chemistry reagent that undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted alkyne-azide cycloaddition (SPAAC), and is commonly used as a linker in antibody-drug conjugate and PROTAC synthesis.
- Azide functional group enables CuAAC and SPAAC reactions.
- Nine-unit PEG spacer improves solubility and provides flexibility.
- High purity (97.7%) suitable for synthetic applications.
- Molecular weight 511.56 and formula C21H41N3O11.
- Supplied as solid quantities for laboratory bioconjugation workflows.
Medchemexpress LLC Boc-NH-PEG3 | 139115-92-7 | MFCD07357496 | ≥98.0% | 249.30 | C11H23NO5 | 1 G
Boc-NH-PEG3 is a Boc-protected PEG3 (triethylene glycol) linker used as a short, hydrophilic spacer in the chemical synthesis of PROTACs and related bioconjugates. It provides a flexible, soluble spacer terminated with a Boc-protected amine that can be deprotected and further functionalized for coupling to ligands or tags. The compound is supplied at high purity and in research-scale pack sizes suitable for synthetic workflows.
- Boc-protected terminal amine for orthogonal deprotection.
- Triethylene glycol spacer gives flexibility and solubility.
- Suitable for PROTAC and general bioconjugation chemistry.
- High purity, suitable for synthetic applications.
- Available in small pack sizes for research-scale synthesis.
- Stable when stored under recommended conditions.
Medchemexpress LLC N-Boc-PEG1-bromide | 164332-88-1 | 97.9% | 268.15 g/mol | C9H18BrNO3 | 500 MG
N-Boc-PEG1-bromide is a Boc-protected polyethylene glycol (PEG1) reagent bearing a terminal bromide, used as a short PEG spacer and alkylating reagent in the synthesis of proteolysis-targeting chimeras (PROTACs) and antibody-drug conjugates (ADCs) for research applications. Typical purity is 97.87% and molecular weight is 268.15 g/mol (CAS 164332-88-1).
- Boc-protected polyethylene glycol reagent with a terminal bromide for alkylation.
- Short PEG spacer (PEG1) to increase solubility and provide spacing.
- Suitable for ADC and PROTAC linker synthesis.
- Typical purity around 97.9% for research use.
- Available as a 500 mg solid package for laboratory synthesis.
Medchemexpress LLC Azido-PEG7-azide | 225523-86-4 | MFCD29764341 | >96.0% | 420.46 g/mol | C16H32N6O7 | 5 MG
Azido-PEG7-azide is a homobifunctional polyethylene glycol (PEG) linker bearing terminal azide groups used for click chemistry and bioconjugation. It provides a seven-unit ethylene glycol spacer that increases hydrophilicity and flexibility, facilitating conjugation in synthesis workflows. Molecular formula C16H32N6O7; molecular weight 420.46 g/mol; CAS 225523-86-4.
- Contains two terminal azide groups for click chemistry.
- Seven-unit PEG spacer increases hydrophilicity and solubility.
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
- Serves as a flexible linker for PROTAC and other bioconjugation applications.
- Supplied in small research pack sizes suitable for synthesis and analysis.
Medchemexpress LLC Azido-PEG9-acid | 1670249-37-2 | MFCD13184977 | 97.7% | 511.56 | C21H41N3O11 | 500 MG
Azido-PEG9-acid is a non-cleavable 9-unit polyethylene glycol (PEG) linker bearing an azide and a terminal carboxylic acid, used for conjugation in antibody-drug conjugate (ADC) and PROTAC synthesis. The azide enables click chemistry (CuAAC and SPAAC), while the carboxylic acid allows amide coupling to amines.
- Non-cleavable 9-unit polyethylene glycol linker.
- Contains an azide group for copper-catalyzed and strain-promoted click chemistry.
- Terminal carboxylic acid suitable for amide coupling reactions.
- Molecular weight about 511.56.
- Purity approximately 97.7% (per manufacturer datasheet).
- Available in 100 MG, 250 MG, 500 MG, 1 G, and 5 G pack sizes.
- Appearance: colorless to light yellow liquid.
- Storage: store pure material at -20°C for long-term stability.
![Medchemexpress LLC Tert-butyl 3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]propionate | 883554-11-8 | MFCD26388566 | >98.0% | 292.37 g/mol | C14H28O6 | 500 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202223.png-250.jpg)
Medchemexpress LLC Tert-butyl 3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]propionate | 883554-11-8 | MFCD26388566 | >98.0% | 292.37 g/mol | C14H28O6 | 500 MG
m-PEG4-Boc is a cleavable four-unit polyethylene glycol (PEG) linker with a tert-butyl (Boc) protected methyl terminus, designed for use in bioconjugation workflows such as antibody-drug conjugates (ADCs) and PROTACs.
- Cleavable 4-unit PEG linker.
- CAS number 883554-11-8.
- Molecular formula C14H28O6.
- Molecular weight 292.37 g/mol.
- Purity >98.0%.
- Typical package 500 mg.
- Recommended storage: solid at -20°C for long-term storage.
![Medchemexpress LLC Tert-butyl 3-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}propionate | 883554-11-8 | MFCD26388566 | >98.0% | 292.37 | C14H28O6 | 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202632.png-250.jpg)
Medchemexpress LLC Tert-butyl 3-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}propionate | 883554-11-8 | MFCD26388566 | >98.0% | 292.37 | C14H28O6 | 1 G
m-PEG4-Boc is a cleavable, PEG-based 4-unit linker supplied as a liquid for use in conjugation chemistry and linker design. It is commonly used as a spacer in the synthesis of antibody-drug conjugates (ADCs) and proteolysis targeting chimeras (PROTACs).
- Cleavable PEG spacer with four ethylene glycol units.
- Provides a tert-butyl (Boc) protected terminal ester.
- Molecular formula C14H28O6 and molecular weight ~292.37 g/mol.
- Available in small laboratory pack sizes, including 1 g.
- Typically supplied as a liquid for ease of handling in solution-phase synthesis.
Medchemexpress LLC Azido-PEG9-acid | 1670249-37-2 | 97.7% | 511.56 g/mol | C21H41N3O11 | 1 G
Azido-PEG9-acid is an azide-terminated 9-unit polyethylene glycol linker with a terminal carboxylic acid. It is used as a non-cleavable PEG linker for conjugation chemistry and click-based bioconjugation applications.
- Non-cleavable 9-unit PEG linker suitable for ADC and PROTAC synthesis.
- Azide functional group enables CuAAC and strain-promoted azide-alkyne cycloaddition (SPAAC).
- Molecular weight 511.56 g/mol; formula C21H41N3O11.
- Purity approximately 97.7%.
- Appearance: colorless to light yellow liquid; storage: -20°C for long-term.
Sigma Aldrich Fine Chemicals Biosciences 1-Methyl-2-pyrrolidinone b1L
N-Methyl-2-pyrrolidinone (N-methylpyrrolidone NMP) is a polar cyclic organic solvent. A study on the impact of NMP on Saccharomyces cerevisiae revealed that it induced aneuploidy. Characteristic properties of NMP include low viscosity excellent dissolving power and enhanced demulsifying property. It is a better alternative to phenol in selectively treating lube feedstock. The behavior of fullerene-C60 in NMP SOLUTIONon has been examined based on electronic absorption and photoluminescence spectral data. A SOLUTIONon of sodium borohydride (NaBH4) in NMP showed increased reactivity towards debromination of alkyl bromide. The enhanced selectivity of NMP-ethylene glycol solvent mixture for aromatic hydrocarbon extraction has been analyzed by gas chromatography.
