Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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2,026 – 2,040 of 6,662 results

2,026

Medchemexpress LLC Articaine hydrochloride | 23964-57-0 | 99.4% | 500 MG

Articaine hydrochloride is a selective inhibitor of voltage-gated sodium channels, exerting local anesthetic activity by inhibiting Na+ influx to block nerve impulse conduction. It also inhibits NF-κB activation and NLRP3 inflammasome pathways, demonstrating anti-inflammatory function. This compound is used in the study of dental local anesthesia and inflammatory-related diseases, such as acute kidney injury.

Selective inhibitor of voltage-gated sodium channels (rNav1.4, hNav1.7, and rNav1.8)
Inhibits Na+ influx to block nerve impulse conduction
Exhibits local anesthetic activity
Inhibits NF-κB activation and NLRP3 inflammasome pathways
Demonstrates anti-inflammatory function
Applicable in dental local anesthesia research
Applicable in inflammatory-related diseases research, such as acute kidney injury

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2,027

Medchemexpress LLC Flavoxate hydrochloride | 3717-88-2 | 99.7% | 427.92 | C24H26ClNO4 | 10 MG

Flavoxate hydrochloride (standard) is an analytical reference standard supplied for research and analytical applications. It is used as a reference in studies of phosphodiesterase activity and lower urinary tract disorders, and displays antispasmodic, muscarinic antagonist, calcium antagonistic, and local anesthetic properties.

Analytical standard for research and method development.
High purity suitable for reference and analytical use.
Available in small, defined package sizes for assay calibration.
Defined chemical identity with molecular weight and formula for traceability.
Applicable to studies of overactive bladder and lower urinary tract conditions.

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2,028

Medchemexpress LLC CHK1-IN-4 hydrochlo | 1MG

CHK1-IN-4 hydrochlo | 1MG

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2,029

Medchemexpress LLC Ly 303511 hydrochloride | 2070014-90-1 | 98.9% | 342.82 g·mol⁻¹ | C19H19ClN2O2 | 10 MG

LY 303511 hydrochloride is a research-grade small molecule (CAS 2070014-90-1) that acts as a structural analogue of LY294002; it enhances TRAIL sensitivity in SHEP-1 neuroblastoma cells and reversibly blocks potassium currents in MIN6 insulinoma cells. Supplied as a 10 mg solid with high purity for in vitro studies. Store sealed and protected from moisture.

High purity (98.9%) suitable for screening and biochemical assays.
Compact 10 mg pack for dose-response and early-stage experiments.
Solid form stable under recommended storage temperatures when sealed.
Documented activity on TRAIL sensitivity and potassium current modulation.
CAS number provided for precise chemical identification.

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2,030

Medchemexpress LLC Berubicin (hydrochloride) | 293736-67-1 | 95.08% | 670.10 | 5 MG

Berubicin hydrochloride is a Doxorubicin analog capable of crossing the blood-brain barrier. It inhibits P-gp and MRP1-mediated efflux, suppressing glioblastoma multiforme (GBM). This compound exhibits toxic effects on leukemia cells by activating nuclear factor κB (NF-κB) and induces apoptosis in neuroblastoma cells. It is suitable for studying nervous system-related tumors.

Can cross the blood-brain barrier
Inhibits P-gp and MRP1-mediated efflux
Suppresses glioblastoma multiforme (GBM)
Exerts toxic effects on leukemia cells by activating nuclear factor κB (NF-κB)
Induces apoptosis in neuroblastoma cells
Useful in the study of nervous system-related tumors

Pricing & Availability

2,031

Medchemexpress LLC Olcegepant hydrochloride | 586368-06-1 | MFCD30738010 | 99.1% | 906.11 | C38H47Br2N9O5·HCl | 10 MG

Olcegepant hydrochloride is a selective non-peptide antagonist of the calcitonin gene-related peptide (CGRP) receptor supplied as the hydrochloride salt for laboratory research. It is provided as a high-purity solid for use in neuroscience and GPCR pharmacology studies.

Hydrochloride salt form, suitable for aqueous formulations.
CAS number 586368-06-1.
Molecular formula C38H47Br2N9O5·HCl and molecular weight 906.11.
High purity (~99.1%) suitable for analytical and preparative studies.
Available in small-scale quantities, e.g., 10 MG, for laboratory use.
Used to probe calcitonin gene-related peptide (CGRP) receptor signaling in preclinical research.

Pricing & Availability

2,032

Medchemexpress LLC VU0357017 hydrochloride | 1135242-13-5 | 98.6% | 369.89 | 100 MG

VU0357017 hydrochloride is a potent, selective, and brain-penetrant allosteric agonist of the M1 muscarinic acetylcholine receptor, with an EC50 of 477 nM. It demonstrates high selectivity for M1, exhibiting no activity at M2-M5 even at concentrations up to 30 μM. This compound is suitable for research related to Alzheimer's disease and schizophrenia.

Potent, selective and brain-penetrant allosteric agonist of M1 muscarinic acetylcholine receptor.
Exhibits an EC50 of 477 nM for M1.
Highly selective for M1, with no activity at M2-M5 up to 30 μM.
Can be used for the research of Alzheimer's disease and schizophrenia.
Induces calcium release and ERK phosphorylation in a concentration-dependent manner in CHO cells.
Reverses scopolamine-induced disruption of the contextual fear conditioning response.

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2,033

Medchemexpress LLC Flavoxate hydrochloride | 3717-88-2 | 99.7% | 1 ML

Flavoxate hydrochloride | 3717-88-2 | 99.7% | 1 ML

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2,034

Medchemexpress LLC Voreloxin hydrochloride | 175519-16-1 | 99.6% | 437.90 | 25 MG

Voreloxin Hydrochloride is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA double-strand breaks, G2 arrest, and apoptosis.

Induces G2 arrest partially through topoisomerase II in A549 lung cancer cell line.
Cytotoxic activity requires DNA intercalation.
Exhibits potent cytotoxic activity in AML cell lines, including MV4-11 and HL-60.
Shows additive or synergistic activity in acute leukemia cell lines when combined with cytarabine.
Causes accumulation of cells in the S and G2 phases of the cell cycle.
Induces bone marrow aplasia in vivo when combined with cytarabine.

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2,035

Medchemexpress LLC Terazosin hydrochloride dihydrate | 70024-40-7 | 99.5% | 1 ML

Terazosin hydrochloride dihydrate is a quinazoline derivative and a competitive, orally active α1-adrenoceptor antagonist. It functions by relaxing blood vessels and aiding in the opening of the bladder. This compound has potential applications in the treatment of benign prostatic hyperplasia (BPH) and high blood pressure. This product is for research use only.

Competitive α1-adrenoceptor antagonist
Relaxes blood vessels
Aids in opening the bladder
Potential for treating benign prostatic hyperplasia (BPH)
Potential for treating high blood pressure
Does not differentiate cloned α1-adrenoceptor subtypes
Can promote stone discharge in the treatment of ureteral stones
Reportedly safe and effective for distal ureteral stones, especially those >5 mm

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2,036

Medchemexpress LLC Alectinib Hydrochloride | 1256589-74-8 | 99.9% | 200 MG

Alectinib (CH5424802; RO5424802; RG7853) Hydrochloride is a potent, selective, and orally available ALK inhibitor. It has an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner). It also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.

Potent and selective ALK inhibitor
Orally available
Effective central nervous system (CNS) penetration
Inhibits ALK F1174L and ALK R1275Q

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2,037

Medchemexpress LLC Amprolium hydrochloride | 137-88-2 | 98.79% | 250 MG

Amprolium hydrochloride is an anti-parasitic drug that is taken orally and acts as an antagonist to thiamine in intestinal absorption. It is for research use only and not sold to patients.

Acts as an antagonist to thiamine in intestinal absorption
Targets Coccidia
Suitable for in vivo and in vitro applications
For research use only

Pricing & Availability

2,038

Medchemexpress LLC 9h-Carbazole-3-methanamine, 9-ethyl-N-methyl-, hydrochloride (1:1) | 1050480-30-2 | 99.3% | 274.79 | 1 ML

PhiKan 083 hydrochloride is a carbazole derivative that binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a Kd of 167 μM, and a relative binding affinity (Kd) of 150 μM in Ln229 cells.

Slows down its thermal denaturation rate.

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2,039

Medchemexpress LLC Carmoterol hydrochloride | 137888-11-0 | 98.7% | 404.89 | C21H25ClN2O4 | 10MG

Carmoterol hydrochloride is a potent, selective, long-acting β2-adrenoceptor agonist supplied as a solid research chemical. It is used in pharmacological and respiratory research to study bronchoconstriction and treatments for asthma and chronic obstructive pulmonary disease (COPD), exhibiting strong bronchodilatory activity and high β2 vs β1 selectivity.

Potent, selective β2-adrenoceptor agonist.
Long-acting bronchodilator activity suitable for respiratory research.
High β2 vs β1 selectivity, reducing off-target cardiac β1 activation.
Supplied as a solid research-grade chemical for laboratory use.
High purity (98.7% by HPLC reported on certificate of analysis).
Molecular formula C21H25ClN2O4, molecular weight 404.89 g·mol-1.

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2,040

Medchemexpress LLC Imeglimin (hydrochloride) | 775351-61-6 | 99.3% | 191.66 | 1 ML

Imeglimin hydrochloride is an oral glucose-lowering agent known for its ability to reduce reactive oxygen species (ROS) production, increase mitochondrial DNA, and improve mitochondrial function. This specific product is provided as a 10 mM solution in 1 mL of DMSO, suitable for various research applications. It is intended for research use only and has not been validated for medical applications.

Reduces reactive oxygen species production
Increases mitochondrial DNA
Improves mitochondrial function
Provided as a 10 mM solution in 1 mL DMSO
Intended for research use only

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Alcohols and polyols

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Medchemexpress LLC Articaine hydrochloride | 23964-57-0 | 99.4% | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Flavoxate hydrochloride | 3717-88-2 | 99.7% | 427.92 | C24H26ClNO4 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CHK1-IN-4 hydrochlo | 1MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ly 303511 hydrochloride | 2070014-90-1 | 98.9% | 342.82 g·mol⁻¹ | C19H19ClN2O2 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Berubicin (hydrochloride) | 293736-67-1 | 95.08% | 670.10 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Olcegepant hydrochloride | 586368-06-1 | MFCD30738010 | 99.1% | 906.11 | C38H47Br2N9O5·HCl | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC VU0357017 hydrochloride | 1135242-13-5 | 98.6% | 369.89 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Flavoxate hydrochloride | 3717-88-2 | 99.7% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Voreloxin hydrochloride | 175519-16-1 | 99.6% | 437.90 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Terazosin hydrochloride dihydrate | 70024-40-7 | 99.5% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alectinib Hydrochloride | 1256589-74-8 | 99.9% | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Amprolium hydrochloride | 137-88-2 | 98.79% | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 9h-Carbazole-3-methanamine, 9-ethyl-N-methyl-, hydrochloride (1:1) | 1050480-30-2 | 99.3% | 274.79 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Carmoterol hydrochloride | 137888-11-0 | 98.7% | 404.89 | C21H25ClN2O4 | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Imeglimin (hydrochloride) | 775351-61-6 | 99.3% | 191.66 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More