Alcohols and polyols
- (1)
- (55)
- (343)
- (39)
- (4)
- (8)
- (7)
- (55)
- (3)
- (7)
- (18)
- (1)
- (4)
- (156)
- (1)
- (64)
- (27)
- (14)
- (3)
- (1)
- (1)
- (10)
- (3)
- (2)
- (2)
- (1)
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- (6)
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- (30)
- (4)
- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (395)
- (6)
- (102)
- (21)
- (50)
- (31)
- (62)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (12)
- (145)
- (116)
- (7)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
- (12)
- (21)
- (5)
- (2)
- (2)
- (2)
- (16)
- (2)
- (30)
- (1)
- (4)
- (1)
- (2)
- (1)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (1)
- (2)
- (2)
- (2)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (8)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (15)
- (12)
- (1)
- (2)
- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (3)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (2)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (5)
- (4)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (5)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (4)
- (3)
- (1)
- (4)
- (5)
- (1)
- (4)
- (5)
- (9)
- (1)
- (5)
- (5)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (5)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (2)
- (2)
- (11)
- (9)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (1)
- (10)
- (1)
- (1)
- (1)
- (2)
- (4)
- (11)
- (1)
- (2)
- (4)
- (20)
- (21)
- (2)
- (8)
- (2)
- (3)
- (3)
- (1)
- (8)
- (4)
- (2)
- (1)
- (1)
- (3)
- (1)
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- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (5)
- (12)
- (9)
- (1)
- (2)
- (1)
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- (1)
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- (1)
- (1)
- (1)
- (7)
- (2)
- (1)
- (2)
- (1)
- (1)
- (5)
- (4)
- (3)
- (1)
- (1)
- (4)
- (6)
- (1)
- (1)
- (1)
- (5)
- (1)
- (4)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (2)
- (5)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (14)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (4)
- (5)
- (2)
- (2)
- (1)
- (10)
- (4)
- (1)
- (9)
- (1)
- (8)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (4)
- (1)
- (1)
- (3)
- (2)
- (4)
- (1)
- (1)
- (1)
- (4)
- (1)
- (5)
- (1)
- (7)
- (1)
- (2)
- (1)
- (7)
- (1)
- (2)
- (1)
- (1)
- (6)
- (1)
- (1)
- (15)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (6)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
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- (1)
- (4)
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- (2)
- (2)
- (1)
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- (2)
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- (1)
- (1)
- (2)
- (12)
- (4)
- (2)
- (1)
- (5)
- (1)
- (1)
- (1)
- (3)
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- (1)
- (2)
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- (1)
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- (5)
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- (2)
- (5)
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- (1)
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- (9)
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- (6)
- (9)
- (3)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
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- (27)
- (4)
- (3)
- (2)
- (1)
- (4)
- (3)
- (2)
- (7)
- (1)
- (18)
- (16)
- (1)
- (4)
- (2)
- (4)
- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (82)
- (12)
- (4)
- (1)
- (3)
- (7)
- (5)
- (1)
- (81)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
- (19)
- (1)
- (21)
- (16)
- (1)
- (2)
- (21)
- (2)
- (2)
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- (1)
- (67)
- (1)
- (1)
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- (1)
- (1)
- (4)
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- (1)
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- (3)
- (3)
- (7)
- (2)
- (2)
- (2)
- (7)
- (4)
- (85)
- (1)
- (5)
- (72)
- (3)
- (5)
- (237)
- (4)
- (2)
- (2)
- (21)
- (279)
- (17)
- (1)
- (6)
- (278)
- (28)
- (2)
- (25)
- (2)
- (3)
- (2)
- (2)
- (2)
- (6)
- (3)
- (2)
- (3)
- (48)
- (3)
- (418)
- (6)
- (3)
- (6)
- (5)
- (47)
- (6)
- (3)
- (1)
- (4)
- (21)
- (16)
- (2)
- (4)
- (11)
- (1)
- (8)
- (2)
- (733)
- (11)
- (3)
- (4)
- (2)
- (9)
- (1)
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- (66)
- (2)
- (2)
- (18)
- (3)
- (4)
- (33)
- (2)
- (31)
- (39)
- (2)
- (3)
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- (3)
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- (6)
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- (1)
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Filtered Search Results
Medchemexpress LLC Cl-amidine hydrochloride | 1373232-26-8 | MFCD22201084 | 99.8% | 347.24 | C14H20Cl2N4O2 | 1 ML
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Cl-amidine hydrochloride is an orally active peptidylarginine deiminase (PAD) inhibitor used in biochemical, cellular, and in vivo research to block protein citrullination and probe PAD-related pathways.
- Inhibits PAD1, PAD3, and PAD4 with reported IC50 values of 0.8 μM, 6.2 μM, and 5.9 μM.
- Available as a 10 mM solution in DMSO or as solid quantities for formulation flexibility.
- High purity (~99.8%) suitable for biochemical and cellular assays.
- Demonstrated activity in cell apoptosis and neutrophil extracellular trap formation assays.
- Shows efficacy in murine models of colitis and sepsis in published studies.
- Provided supporting documents: data sheet, SDS, COA, HNMR, RP-HPLC, and LCMS.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Antalarmin hydrochloride | 220953-69-5 | MFCD05664721 | 99.9% | 415.01 g/mol | C24H35ClN4 | 1 ML
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Antalarmin hydrochloride is a non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist used in research to suppress CRH-induced ACTH secretion and to study stress- and inflammation-related responses in animal models.
- Selective CRHR1 antagonist with reported Ki ≈ 1 nM.
- CAS number 220953-69-5.
- Molecular formula C24H35ClN4, MW 415.01 g/mol.
- Available as a solid or as a 10 mM solution in DMSO (1 mL).
- High purity (~99.9%) suitable for analytical and in vivo preparations.
- Recommended storage: solid at -20°C; in solvent store at -80°C for long term.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC SB-408124 Hydrochloride | 1431697-90-3 | 98.8% | C19H19ClF2N4O | 50 MG
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SB-408124 Hydrochloride is a selective non-peptide orexin receptor 1 (OX1) antagonist, which has demonstrated potent activity with Ki values of 57 nM and 27 nM in whole cell and membrane assays, respectively. It exhibits a high degree of specificity, showing 50-fold selectivity over the OX2 receptor. This compound is intended for research purposes only and is not sold to patients.
- Selective non-peptide orexin receptor 1 (OX1) antagonist.
- Ki values of 57 nM (whole cell) and 27 nM (membrane).
- Exhibits 50-fold selectivity over OX2 receptor.
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Medchemexpress LLC VTP-27999 (Hydrochloride) | 1264191-73-2 | 98.2% | C26H42Cl2N4O5 | 50 MG
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VTP-27999 Hydrochloride is an alkyl amine Renin inhibitor. It is useful for Hypertension and End-Organ Diseases. This product is for research use only and not sold to patients.
- Alkyl amine Renin inhibitor
- Useful for hypertension and end-organ diseases
- For research use only
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![Medchemexpress LLC 3-[[(1R,2S)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-(3-methoxyphenyl)propan-1-one;hydrochloride | 16777-42-7 | 99.9% | 349.85 g·mol⁻¹ | C19H24ClNO3 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000243265.png-250.jpg)
Medchemexpress LLC 3-[[(1R,2S)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-(3-methoxyphenyl)propan-1-one;hydrochloride | 16777-42-7 | 99.9% | 349.85 g·mol⁻¹ | C19H24ClNO3 | 5 MG
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Oxyfedrine hydrochloride is a vasodilator and an orally active β-adrenoreceptor agonist used in cardiovascular research. It decreases the tonicity of coronary vessels and has documented in vitro and in vivo effects on aldehyde dehydrogenase activity, myogenic activity, and blood viscosity.
- High purity (99.92%) suitable for research applications.
- Orally active β-adrenoreceptor agonist with vasodilatory activity.
- Molecular formula C19H24ClNO3; molecular weight 349.85 g·mol⁻¹.
- Solid, white to off-white appearance for easy handling.
- Soluble in DMSO (175 mg/mL); ultrasonic and newly opened DMSO recommended.
- Certificate of analysis available to support quality control.
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Medchemexpress LLC Bambuterol hydrochloride | 81732-46-9 | 403.90 | 10MM/1ML
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Bambuterol hydrochloride is a long-acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma. It also serves as a proagent of terbutaline. While contraindicated in pregnancy and individuals with seriously impaired liver function, it can be used by people with renal impairment with dose adjustments.
- Acts as a long-acting beta-adrenoceptor agonist
- Effective in the treatment of asthma
- Functions as a proagent of terbutaline
- Suitable for use by individuals with renal impairment (with dose adjustments)
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Medchemexpress LLC VU6036720 hydrochloride | 99.65% | 473.39 | 50 MG
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VU6036720 hydrochloride is a potent and specific inhibitor of Kir4.1/5.1 channels. It is suitable for various research applications.
- Inhibits Kir4.1/5.1 channels with an IC50 value of 0.24 μM.
- Can be used for the research of brain and kidney.
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Medchemexpress LLC PRT062607 Hydrochloride | 1370261-97-4 | C19H24ClN9O | 100 MG
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PRT062607 (P505-15) Hydrochloride is an orally available Syk inhibitor (IC50: 1 nM) that inhibits inflammation and induces apoptosis. It also demonstrates potent antitumor activity in tumor xenograft mouse models.
- Inhibits phosphorylation of ERK(Y204), AKT(S473), and SYK(Y352) in Ramos cells.
- Inhibits BLNK Tyr84 phosphorylation.
- Inhibits B cell antigen receptor-mediated B cell signaling and activation in human whole blood.
- Inhibits Fc receptor 1-mediated induced basophil degranulation.
- Demonstrates significant activity against various kinases including Fgr, MLK1, Yes, Flt3, PAK5, Lyn, cSRC, Lck, Pyk, and FAK.
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Medchemexpress LLC Bleomycin (hydrochloride) | 67763-87-5 | 99.5% | 5 MG
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Bleomycin hydrochloride is a DNA synthesis inhibitor, a DNA damaging agent, and an antitumor antibiotic. It is primarily used for research purposes, including the creation of animal models of pulmonary fibrosis.
- Inhibits DNA synthesis.
- Acts as a DNA damaging agent.
- Functions as an antitumor antibiotic.
- Useful for creating animal models of pulmonary fibrosis.
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Medchemexpress LLC Dopexamine hydrochloride | 86484-91-5 | 429.42 | 5 MG
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Dopexamine hydrochloride is a β2 adrenergic receptor agonist and a dopamine analogue with agonist activity at β2 and dopaminergic receptors. It can attenuate systemic inflammatory response, reduce tissue leukocyte infiltration, and protect against organ injury at doses that do not alter global hemodynamics or regional microvascular flow. It also reduces the systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress, without substantially changing systemic hemodynamics.
- β2 adrenergic receptor agonist
- Dopamine analogue with agonist activity at β2 and dopaminergic receptors
- Attenuates systemic inflammatory response
- Reduces tissue leukocyte infiltration
- Protects against organ injury
- Reduces systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress
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Medchemexpress LLC AkaLumine hydrochloride | 2558205-28-8 | 99.9% | 338.85 | 10 MG
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AkaLumine hydrochloride is an analogue of D-luciferin that emits near-infrared (NIR) light (λmax=677 nm) when reacting with native firefly luciferase (Fluc) protein. It offers high tissue-penetration and increased detection sensitivity from deep-tissue targets.
- Near-infrared (NIR) emission allows for high tissue-penetration.
- Enhances detection sensitivity from deep-tissue targets.
- Functions similarly to D-luciferin with a specified Km for recombinant firefly luciferase.
- Can be used to detect Akaluc expression in vitro and for subcutaneous/orthotopic tumor mouse imaging in vivo.
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Medchemexpress LLC Midodrine (hydrochloride) | 43218-56-0 | 99.9% | 25 MG
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Midodrine hydrochloride is a selective and orally active adrenergic α1-receptor agonist. It strengthens vascular contraction and can be used for research on cardiovascular diseases such as orthostatic hypotension.
- Strengthens vascular contraction
- Increases p-AMPK and PPARδ expression in C2C12, HL1, and HepG2 cells
- Increases Ca2+ in C2C12, HL1, and HepG2 cells
- Increases maximal mitochondrial oxidative phosphorylation and ATP content in C2C12 cells
- Reduces cellular lipid content in 3T3-L1 cells
- Reduces platelet-activating factor (Paf)-induced death in mice
- Shows anti-hypotensive effects in orthostatic hypotension rat models
- Relieves hypertension in spontaneously hypertensive rat models
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Medchemexpress LLC Moexipril (hydrochloride) | 82586-52-5 | 98.4% | 25 MG
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Moexipril hydrochloride is an orally active inhibitor of angiotensin-converting enzyme (ACE) that becomes effective after being hydrolyzed to moexiprilat (hydrochloride). This compound demonstrates significant antihypertensive and neuroprotective effects.
- Orally active inhibitor of angiotensin-converting enzyme (ACE).
- Becomes effective after hydrolysis to moexiprilat.
- Exhibits antihypertensive and neuroprotective effects.
- High potency against plasma ACE and purified ACE from rabbit lung.
- Significantly reduces damaged neurons in a dose-dependent manner.
- Attenuates Fe2+/3+-induced neurotoxicity.
- Does not cause significant changes in apoptotic neurons.
- Does not cross the blood-brain barrier.
- Shows dose-dependent antihypertensive effects in various animal models.
- Reduces infarct area on mouse brain surface.
- Attenuates cortical infarct volume in rat brain.
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Medchemexpress LLC SAR407899 (hydrochloride) | 923262-96-8 | 99.1% | 280.75 | 5 MG
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SAR407899 hydrochloride is a selective, potent, and ATP-competitive ROCK inhibitor. It has an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively. It inhibits ROCK-2 more effectively than ROCK-1. This product exhibits potent vasorelaxant activity in various isolated arteries and dose-dependently lowers blood pressure in hypertensive SHRs. It also increases penile length in healthy and diabetic rabbits.
- Selective and potent ROCK inhibitor
- ATP-competitive mechanism of action
- Inhibits MYPTT696 phosphorylation
- Blocks thrombin-induced effects
- Inhibits cell proliferation and migration
- Potent vasorelaxant activity
- Reduces blood pressure
- Increases penile length
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Medchemexpress LLC Octodrine hydrochloride | 5984-59-8 | 98.0% | 5 G
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Octodrine (2-Amino-6-methylheptane) is a central nervous activator that increases the uptake of dopamine and noradrenaline. It is found to increase the pain threshold, cardiac rate (positive chronotropic effect), and myocardial contractility (positive inotropic effect).
- Increases the uptake of dopamine and noradrenaline
- Increases pain threshold
- Increases cardiac rate (positive chronotropic effect)
- Increases myocardial contractility (positive inotropic effect)
- Functions as a central nervous activator
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