Alcohols and polyols
- (1)
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- (395)
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- (102)
- (21)
- (50)
- (31)
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- (13)
- (14)
- (1)
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- (1)
- (26)
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- (1)
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- (1)
- (462)
- (9)
- (46)
- (11)
- (45)
- (6)
- (1)
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- (10)
- (145)
- (114)
- (6)
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- (1)
- (1)
- (1)
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- (1)
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- (1)
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- (15)
- (1)
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- (6)
- (2)
- (2)
- (2)
- (2)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (2)
- (5)
- (4)
- (33)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (8)
- (7)
- (7)
- (2)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (3)
- (1)
- (15)
- (12)
- (1)
- (2)
- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (17)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (7)
- (4)
- (1)
- (1)
- (3)
- (6)
- (11)
- (5)
- (3)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (2)
- (1)
- (3)
- (2)
- (10)
- (1)
- (2)
- (4)
- (4)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (1)
- (5)
- (3)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (5)
- (1)
- (2)
- (2)
- (6)
- (14)
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- (1)
- (2)
- (1)
- (1)
- (1)
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- (1)
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- (11)
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- (1)
- (1)
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- (1)
- (1)
- (3)
- (1)
- (1)
- (10)
- (1)
- (1)
- (1)
- (2)
- (4)
- (11)
- (1)
- (2)
- (4)
- (20)
- (21)
- (1)
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- (3)
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- (8)
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- (2)
- (1)
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- (60)
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- (1)
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- (11)
- (82)
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- (1)
- (81)
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- (378)
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- (40)
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- (704)
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Filtered Search Results
Medchemexpress LLC Ssr180711 hydrochloride | 446031-79-4 | 99.9% | 361.66 | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Ssr180711 hydrochloride | 446031-79-4 | 99.9% | 361.66 | 50 MG
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Medchemexpress LLC Reserpine (hydrochloride) | 16994-56-2 | 645.14 | 1 ML
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Reserpine (hydrochloride) | 16994-56-2 | 645.14 | 1 ML
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Medchemexpress LLC Aprindine hydrochloride | 33237-74-0 | 99.0% | 358.95 g·mol⁻¹ | C22H31ClN2 | 10 MG
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Aprindine hydrochloride is a class I-b anti-arrhythmic research compound that blocks sodium channels (INa) and is used to study cardiac electrophysiology. Supplied as the hydrochloride salt in small milligram quantities, it is intended for analytical and preclinical research applications.
- Class I-b anti-arrhythmic agent; sodium channel blocker.
- Hydrochloride salt form for improved solubility.
- Available in small, precise milligram pack sizes.
- High purity suitable for analytical and preclinical studies.
- Used in electrophysiology and cardiovascular research applications.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Amelparib hydrochloride | 98.4% | 379.88 | 1 MG
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Amelparib hydrochloride is a potent, orally active, and water-soluble inhibitor of PARP-1. It inhibits PARP-1 activity (IC50 = 18.5 nM) and cellular PAR formation (IC50 = 10.7 nM). This compound is a potential neuroprotective agent and has potential for the research of acute ischaemic stroke.
- Potent, orally active, and water-soluble inhibitor of PARP-1
- Inhibits PARP-1 activity (IC50 = 18.5 nM)
- Inhibits cellular PAR formation (IC50 = 10.7 nM)
- Potential neuroprotective agent
- Potential for research of acute ischaemic stroke
- Appearance: Solid
- Color: Off-white to light yellow
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ALADDIN SCIENTIFIC CORPORATION Ninhydrin, 5g
Used in the detection and assay of peptides amino acids amines and amino sugars yielding highly fluorescent ternary compounds with aldehydes and primary amines Reaction with sarcosine or proline gives azomethine ylides Application It can be used for the detection of peptides amino acids amino acids and amino sugars and can produce strong fluorescent ternary compounds with aldehydes and primary amines Reacts with sarcosine or proline to form methylimine Ylide Ninhydrin (ninhydrin hydrate) can be used as a reagent for the determination of amino acids and peptides by photometry and colorimetry It can also be used to prepare ninhydrin reagents by mixing ninhydrin with hydroninhydrin (reduced form of ninhydrin) in dimethyl sulfoxide This reagent can be used for the manual ninhydrin method to quantify amino acids It can be used to detect free amino groups in amino acids peptides and proteins
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Medchemexpress LLC Voreloxin Hydrochloride | 175519-16-1 | 99.58% | 437.90 | 50 MG
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Voreloxin Hydrochloride is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis.
- Inhibits topoisomerase II activity.
- Induces site-selective DNA DSB.
- Causes G2 arrest.
- Leads to apoptosis.
- Shows potent cytotoxic activity in AML cell lines.
- Exhibits additive or synergistic activity with cytarabine in acute leukemia cell lines.
- Reduces bone marrow cellularity in mice.
- Causes reversible decrease in myeloid and lymphoid cells in vivo.
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Medchemexpress LLC Alosetron Hydrochloride | 122852-69-1 | 99.6% | C17H19ClN4O | 100 MG
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Alosetron Hydrochloride is a potent and highly selective serotonin 5-HT3 receptor antagonist used in research for irritable bowel syndrome (IBS). It blocks the fast 5HT3-mediated depolarization of guinea-pig myenteric and submucosal neurons, with an IC50 of approximately 55 nM. It also attenuates visceral nociceptive effects of rectal distension in dogs and demonstrates anti-inflammatory properties.
- Potent and highly selective serotonin 5-HT3 receptor antagonist
- Applicable for research in irritable bowel syndrome (IBS)
- Blocks fast 5HT3-mediated depolarization of guinea-pig myenteric and submucosal neurons, with an IC50 of approximately 55 nM
- Attenuates visceral nociceptive effects of rectal distension in dogs
- Demonstrates anti-inflammatory effects
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Medchemexpress LLC Alosetron Hydrochloride | 122852-69-1 | 99.63% | C17H19ClN4O | 50 MG
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Alosetron Hydrochloride is a potent and highly selective antagonist of the serotonin 5-HT3 receptor. It is researched for its application in irritable bowel syndrome (IBS). The compound effectively blocks the rapid 5HT3-mediated depolarization in guinea-pig myenteric and submucosal neurons, with an IC50 of approximately 55 nM. It also demonstrates an ability to lessen the visceral nociceptive effects of rectal distension in conscious or anesthetized dogs, and exhibits anti-inflammatory properties.
- Highly selective antagonist of the serotonin 5-HT3 receptor.
- Under investigation for irritable bowel syndrome.
- Blocks 5HT3-mediated depolarization.
- Attenuates visceral nociceptive effects.
- Exhibits anti-inflammatory effects.
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Medchemexpress LLC Aplaviroc hydrochloride | 461023-63-2 | 99.9% | 614.17 | 100 MG
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Aplaviroc hydrochloride is a potent CCR5 antagonist, effective against wild-type R5 HIV-1 strains with IC50 values of 0.1 to 0.4 nM. It also suppresses the infectivity and replication of HIV-1MDR variants at low concentrations. This compound binds to CCR5 with high affinity and has been shown to suppress R5 HIV-1 viremia in animal models. Aplaviroc hydrochloride has been involved in multiple clinical trials for HIV infection.
- Potent CCR5 antagonist
- Effective against wild-type R5 HIV-1 strains
- Suppresses HIV-1MDR variants
- Binds to CCR5 with high affinity
- Suppresses R5 HIV-1 viremia in animal models
- Investigated in clinical trials for HIV infection
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Medchemexpress LLC Adrogolide hydrochloride | 166591-11-3 | 99.6% | 435.96 | C22H26ClNO4S | 25 MG
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Adrogolide hydrochloride is a research-grade prodrug converted rapidly in plasma to the dopamine D1 receptor agonist A-86929. Supplied as the hydrochloride salt, it is intended for laboratory research use only and is provided in pre-weighed quantities for assay preparation.
- High purity (≈99.6%) suitable for research applications.
- Molecular weight 435.96 and formula C22H26ClNO4S.
- Available in pre-weighed small quantities for in vitro and in vivo studies.
- Soluble in DMSO for assay preparation.
- Acts as a prodrug to the D1 receptor agonist A-86929.
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Medchemexpress LLC Cct241533 hydrochloride | 1431697-96-9 | 98.55% | 478.94 | 50 MG
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CCT241533 hydrochloride is a potent and selective CHK2 inhibitor with an IC50 of 3 nM and a Ki of 1.16 nM. It exhibits minimal cross-reactivity against a panel of kinases at 1 μM. X-ray crystallography confirms its binding to CHK2 in the ATP pocket. The compound blocks CHK2 activity in human tumor cell lines in response to DNA damage, significantly enhancing the cytotoxicity of two structurally distinct PARP inhibitors. Clear induction of the pS516 CHK2 signal by PARP inhibitor alone is abolished by CCT241533. The cytotoxicity (GI50) in HT-29, HeLa, and MCF-7 cells is 1.7, 2.2, and 5.1 μM, respectively.
- Potent and selective CHK2 inhibitor (IC50=3 nM)
- 63-fold selectivity over CHK1 (IC50=190 nM)
- Low hERG inhibition (IC50=22 μM)
- Blocks CHK2 activity in human tumor cell lines in response to DNA damage
- Enhances cytotoxicity of PARP inhibitors
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Medchemexpress LLC Olcegepant hydrochloride | 586368-06-1 | MFCD07772306 | 99.1% | 906.11 | C38H47Br2N9O5·HCl | 50 MG
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Olcegepant hydrochloride is a potent, selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor, provided as the hydrochloride salt for preclinical research use. The compound is supplied with reported high purity and is offered in multiple quantities and solution formats for laboratory studies.
- Potent, selective antagonist of the CGRP1 receptor.
- Reported high purity (~99.1%).
- Available in multiple sizes, including 5 mg-500 mg, and as DMSO solutions.
- Molecular formula C38H47Br2N9O5·HCl; molecular weight 906.11 g/mol.
- For research use only; not for human or clinical use.
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Medchemexpress LLC Agn 192403 hydrochloride | 175521-95-6 | >95.0% | 189.73 | C10H19N·HCl | 25 MG
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AGN 192403 hydrochloride is a small-molecule I1 (imidazoline-1) receptor ligand used in cardiovascular and neurological research. It has been reported to show neuroprotective effects, and in cellular studies to bind the TMED9 cargo receptor, affecting MUC1-fs trafficking. The compound is used as a research tool to probe imidazoline receptor pharmacology and related mitochondrial pathways.
- Selective I1 receptor activity suitable for receptor pharmacology studies.
- Reported neuroprotective effects for neurological research applications.
- Demonstrated interaction with TMED9, useful in cellular trafficking studies.
- Applicable to in vitro assays and exploratory in vivo models.
- Available from multiple research suppliers with supporting COA/technical data.
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Medchemexpress LLC SRI-011381 hydrochloride | 2070014-88-7 | 99.6% | 365.94 g/mol | C20H32ClN3O | 10 MG
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SRI-011381 hydrochloride is an orally active TGF-β signaling agonist used in research. It promotes fibroblast proliferation and increases TGF-β1, NALP3, collagen-1, and α-SMA expression in vitro, and reduces neuronal loss and inflammatory infiltration in animal models.
- Orally active TGF-β signaling agonist for in vivo and in vitro studies.
- Promotes fibroblast proliferation and extracellular matrix marker expression.
- Demonstrated neuroprotective effects in animal disease models.
- High purity suitable for research applications.
- Soluble in DMSO, water, and PBS with ultrasonic assistance.
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Medchemexpress LLC Littorine hydrochloride | 21956-47-8 | >95.0% | 325.83 | C17H24ClNO3 | 5 MG
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Littorine hydrochloride is the hydrochloride salt of littorine, an alkaloid found in Anthocercis fittorea and Datura species. It is supplied as a small-scale research chemical with documented molecular and solubility data for in vitro preparation.
- Hydrochloride salt of littorine, an alkaloid found in plant species.
- Molecular formula C17H24ClNO3; molecular weight 325.83.
- Soluble in DMSO at 50 mg/mL (153.45 mM); may require ultrasonic treatment.
- Available in small research quantities (1 mg, 5 mg, 10 mg).
- Store under conditions recommended in the certificate of analysis.
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