Flavonoids
Apexbio Technology LLC APIGENIN-7-O-B-D-GLC-5mg
Apigenin-7-O- -D-glucopyranoside (CAS No 578-74-5) is a naturally occurring flavonoid glycoside found in various plant species particularly in the family of Lamiaceae It falls within the research category of phytochemistry and pharmacology Its mechanism of action involves modulation of several signaling pathways including those associated with oxidative stress and inflammation potentially targeting enzymes like cyclooxygenase and lipoxygenase In vitro studies demonstrate activity typically within the nanomolar to low micromolar range showing promise in anti-inflammatory and antioxidant applications It is commonly used in cell models to study cancer cell proliferation and apoptosis and has been explored in animal studies for its potential neuroprotective effects Additionally it has applications in drug screening to identify novel therapeutic agents Experimental concentrations typically depend on the specific research design
Cayman Chemical EpIcatechIn Galate 10mg
A natural catechin which inhibits the growth of cancer cells and has anti-inflammatory effects; has potent antioxidant activity and facilitates the killing of methicillin-resistant strains of S. aureus
TARGETMOL CHEMICALS INC APIGENIN-7-GLUCURONIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Apigenin-7-glucuronide (Apigenin 7-O-glucuronide) possesses multiple activities including antioxidant anti-inflammatory and aldose reductase inhibitory activities it can inhibit MMP activities (IC50s 12.87 22.39 17.52 0.27 uM for MMP-3 MMP-8 MMP-9 MMP-13 respectively). purity: 99%
Apexbio Technology LLC (-)-epicatechin gallate 1257-08-5 20mg
(-)-Epicatechin gallate (ECG) is a catechin compound abundant in green tea displaying bioactivity to modulate cell proliferation apoptosis and gene expression pathways In colon HCT-116 cells ECG induces apoptosis through activating transcription factor 3 (ATF3) regulated via activation of early growth response protein 1 (EGR-1) In these cancer cells ECG upregulates apoptotic factor NAG-1 and increases caspase-3 activity at concentrations around 150 M ECG s cytotoxic potency differs among cell types with an NR50 (midpoint cytotoxic concentration) of approximately 67 M in HSC-2 oral cancer cells while normal human fibroblast HGF-2 cells show greater resistance with an NR50 near 100 M ECG metabolites identified in rat urine include various O-methylated derivatives useful as biomarkers for metabolism studies ECG serves as a research tool for oncology mechanisms and apoptosis signaling pathways
Cayman Chemical Luteolin Inhibitors
A common dietary phenolic flavone; inhibits soybean and reticulocyte 15-lipoxygenases (IC50 = 0.6 µM); inhibits the release of TNFα from neutrophils; inhibits matrix metalloproteinases
Cayman Chemical Luteolin Inhibitors
A common dietary phenolic flavone; inhibits soybean and reticulocyte 15-lipoxygenases (IC50 = 0.6 µM); inhibits the release of TNFα from neutrophils; inhibits matrix metalloproteinases
Sigma Aldrich Fine Chemicals Biosciences Epicatechin 90 HPLC5G
Epicatechin is a flavanol. Cacao products are rich in epicatechin.
Medchemexpress LLC Luteolin 7-O-glucuronide | 29741-10-4 | 98.7% | 462.36 | C21H18O12 | 10 MG
Luteolin 7-O-glucuronide is a flavone glycoside used as a research reagent to study matrix metalloproteinase (MMP) inhibition and inflammation-related pathways. It is supplied as a light-yellow solid and as a DMSO solution, and is provided at high purity for biochemical assays and analytical standards.
- Cas number: 29741-10-4.
- Molecular weight: 462.36.
- Typical purity: 98.7% (batch level).
- Physical forms: solid and 10 mM solution in DMSO.
- Typical package sizes include 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.
- Common applications: enzymatic inhibition assays and analytical standardization.
Medchemexpress LLC Apigenin (4',5,7-Trihydroxyflavone) | 520-36-5 | 99.2% | 50 MG
Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor and inhibits cell proliferation. It suppresses the clone formation of SGC-7901 cells in a dose- and time-dependent manner.
- Competitive CYP2C9 inhibitor
- Inhibits cell proliferation
- Suppresses SGC-7901 cell clone formation