Flavonoids
TARGETMOL CHEMICALS INC Epigallocatechin-3-3-O-methyl
Also available in 1 mL, 5 mg, 10 mg, 25 mg and bulk. Please contact Fisher for quotes. (-)-Epigallocatechin-3-(3''-O-methyl) gallate ((-)-EGCG-3''-O-ME) is a natural product isolated from tea leaves with potent antioxidant, cytotoxic, and antibacterial properties, and it improves the adhesive stability of etching rinsing adhesives to dentin. Purity 99.59%
AdipoGen Catechin
Chemical. CAS 18829-70-4. Formula C15H14O6. MW 290.27. Catechins have wide biological functionality, including antioxidant, anti-inflammatory, antiviral and anticancer activities. Catechins also play a key role in regulating carbohydrate and lipid metabolism. --Catechin is comparatively less bioavailable than the stereoisomer -catechin for intestinal absorption. It shows antioxidant free radical scavenging and antidiabetic activities. --Catechin has been shown to be a stereoselective PPARgamma agonist. It activates PPARgamma in a dose-dependent fashion, promotes adipocyte differentiation and increases sensitivity to insulin. It markedly suppresses the expression of Kruppel-like factor 7 KLF7 protein, which has recently been reported to inhibit the expression of adiponectin and other adipogenesis related genes, including leptin, PPARgamma, C/EBPalpha, and aP2 in adipocytes. It also has shown to have anti-reverse transcriptase activity and maltase inhibitory activity.
eMolecules 35244-11-2 | 2-(2-Hydroxyphenyl)-4H-Chromen-4-One | AA Blocks LLC | MFCD00017673 | 238.242 | C15H10O3 | 0.000 | Oc1ccccc1-c1cc(=O)c2ccccc2o1 | 1g | 913100346
2-(2-Hydroxyphenyl)-4H-Chromen-4-One | AA Blocks LLC | 35244-11-2 | MFCD00017673 | 238.242 | C15H10O3 | 0.000 | Oc1ccccc1-c1cc(=O)c2ccccc2o1 | 1g | 913100346
Medchemexpress LLC 4H-1-benzopyran-4-one, 2-(4-hydroxyphenyl)- | 4143-63-9 | MFCD00017687 | 97.0% | 238.24 g/mol | C15H10O3 | 25 MG
4′-Hydroxyflavone is a flavone-class small molecule for biochemical and pharmacological research. It is a reported aldose reductase inhibitor (IC50 = 12 μM) and is supplied as a purified solid suitable for in vitro assays, target validation, and screening studies. Typical analytical data include CAS 4143-63-9, molecular formula C15H10O3, and molecular weight 238.24 g/mol.
- Reported aldose reductase inhibitor (IC50 = 12 μM).
- High purity solid (97.0%).
- Characterized by CAS 4143-63-9 and molecular formula C15H10O3.
- Suitable for biochemical assays, target validation, and screening.
- Available in small research pack sizes for laboratory use.
Selleck Chemical LLC Troxerutin S2369-1g
Troxerutin a natural bioflavonoid isolated from Sophora japonica has been reported to have many benefits and medicinal properties Troxerutin also known as vitamin P4 is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species (ROS) and depress ER stress-mediated NOD activation
Medchemexpress LLC 7-Hydroxyflavone | 6665-86-7 | 10 MG
7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis* with anti-inflammatory activity. It protects renal cells from nicotine (NIC)-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway. This compound inhibits PKM2 with an IC50 of 2.12 μM and also inhibits COX-2 and 5-LOX with IC50s of 27 μg/mL and 33 μg/mL, respectively. 7-Hydroxyflavone is orally active.
- Isolated from *Clerodendrum phlomidis*.
- Exhibits anti-inflammatory activity.
- Protects renal cells from nicotine-associated cytotoxicity.
- Inhibits PKM2, COX-2, and 5-LOX.
- Orally active.
- Inhibits EV71 3C protease and viral replication.
- Antioxidant properties: decreases MDA and ROS, increases SOD and GSH.
- Ameliorates ischemia/reperfusion injury and neuropathic pain.
- Improves hepatic steatosis and regulates blood glucose metabolism in NAFLD models.
Medchemexpress LLC Chrysin-7-O-glucuronide | 35775-49-6 | 1 MG
Chrysin-7-O-glucuronide is a flavonoid extracted from *Scutellaria baicalensis* that exhibits antioxidant activity. It is intended for research use only.
- Purity: 99.47%
- Source: Flavonoid extracted from *Scutellaria baicalensis*.
- Activity: Antioxidant activity.
- Appearance: Solid, off-white to yellow color.
- Solubility (in vitro): 50 mg/mL (116.18 mM) in DMSO.
- Structure classification: Flavonoids, flavones, phenols, monophenols.
- Initial source: Plants (Leguminosae, Bignoniaceae, Labiatae).
TARGETMOL CHEMICALS INC CHRYSIN-7-O-GLUCURONIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Chrysin-7-O-glucuronide (Chrysin 7-O-beta-D-glucopyranuronoside) is a natural product with antioxidant activitypurity: 99%
Apexbio Technology LLC Chrysin 480-40-0 10mM (in 1mL DMSO)
Chrysin a naturally occurring flavonoid compound exhibits antioxidant activity and has been extensively studied in biomedical research contexts Primarily recognized for its capacity to modulate inflammatory signaling pathways and tumor-related cellular processes chrysin specifically acts through the inhibition of hypoxia-inducible factor-1 alpha (HIF-1 ) a critical regulator in cellular response to hypoxia Additionally chrysin promotes cell apoptosis indicating its potential role in antitumor protocols In experimental settings it serves as a biological tool to explore mechanisms underlying inflammation cancer progression and oxidative stress-mediated pathologies
Medchemexpress LLC 7-Hydroxyflavone | 6665-86-7 | MFCD00006835 | 50 MG
7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis* that exhibits anti-inflammatory activity. It protects renal cells from nicotine-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway. This orally active compound also inhibits PKM2, COX-2, and 5-LOX, and has demonstrated antioxidant activity and efficacy in various animal models.
- Isolated from *Clerodendrum phlomidis*
- Exhibits anti-inflammatory activity
- Protects renal cells from nicotine-associated cytotoxicity
- Inhibits PKM2, COX-2, and 5-LOX
- Orally active
- Reduces malondialdehyde (MDA) and reactive oxygen species (ROS) levels
- Increases superoxide dismutase (SOD) and glutathione (GSH) levels
- Ameliorates ischemia/reperfusion injury
- Improves high-fat diet-induced non-alcoholic fatty liver disease and obesity
- Purity of 99.89%
- Appearance is a white to off-white solid