Flavonoids
Medchemexpress LLC Catechin (Standard) | 154-23-4 | 290.27 | 100 MG
Catechin (Standard) is the analytical standard of Catechin, intended for research and analytical applications. It inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
- Used as an analytical reference standard.
- Commonly used in qualitative research experiments.
- Commonly used in quantitative research experiments.
- Commonly used in methodological research experiments.
- Suitable for HPLC.
- Suitable for GC.
- Suitable for MS.
Medchemexpress LLC Diosmin | 520-27-4 | 97.5% | 608.54 g/mol | C28H32O15 | 10 MG
Diosmin is an analytical reference standard of the flavonoid diosmin supplied for research and analytical applications. It is intended for assay development, method validation, and chromatographic analysis.
- Purity 97.54% (analytical grade).
- Cas number 520-27-4 for unambiguous identification.
- Molecular formula C28H32O15 and molecular weight 608.54 g/mol.
- Suitable for HPLC, LC-MS, and other analytical workflows.
- Available in small pack sizes, such as 10 MG, for reference use.
Medchemexpress LLC 4H-1-benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)- | 520-36-5 | 270.24 | 200 MG
Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM. It inhibits cytochrome P450 2C9 (CYP2C9) with a Ki of 2 μM in the CYP2C9 RECO system, a purified, reconstituted enzyme system. This natural flavonoid possesses broad biological properties including antioxidative, anti-inflammatory, anticancer, and neuroprotective effects.
- Inhibits cell proliferation
- Suppresses clone formation of SGC-7901 cells
- Alleviates Adriamycin-induced myocardial injury
- Reduces serum aspartate amino transferase (AST) release
- Reduces serum lactate dehydrogenase (LDH) release
- Reduces serum creatine kinase (CK) contents
Medchemexpress LLC Flavanone | 487-26-3 | 1 ML
Flavanone is a naturally occurring flavone with inhibitory activity for human estrogen synthetase (aromatase) and acts as an inhibitor for the ERK/p38/NF-κB signaling pathway. It exhibits oral activity and antitumor efficacy, demonstrating its potential in various biological processes.
- Inhibits cell proliferation, migration, and invasion of A549 cells
- Arrests cell cycle at G1 phase in vitro
- Inhibits expression of MMP-2, u-PA, cyclin D1, and CDK2
- Promotes generation of TIMP-2 and PAI-1
- Exhibits antitumor efficacy in C57BL/6J mouse models
- Limits tumor growth and inhibits metastasis of LLC cells in vivo
Medchemexpress LLC 6-Methylflavone | 29976-75-8 | 1 ML
6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors, enhancing the normal response to GABA at concentrations from 1 to 100 μM. This product is intended for research use only.
- Activates α1β2γ2L and α1β2 GABAA receptors
- Enhances GABA response
- High purity (99.77%)
- Supplied as a 10 mM solution in DMSO
- Suitable for in vitro research applications
Medchemexpress LLC Luteolin-4'-O-glucoside | 6920-38-3 | 5 MG
Luteolin-4'-O-glucoside is identified as an IL-5 inhibitor with an IC50 of 3.7 μM. It exhibits resistance to hyperuricemia and acute gouty arthritis activity, and also demonstrates anticancer activity.
- It is an interleukin-5 (IL-5) inhibitor.
- It has an IC50 of 3.7 μM against IL-5.
- It resists hyperuricemia.
- It resists acute gouty arthritis activity.
- It shows anticancer activity.
- It exhibits cytotoxic activity against NCI-H929, U266, and OPM2 cell lines.
Medchemexpress LLC 4'-Hydroxyflavanone | 6515-37-3 | 50 MG
4'-Hydroxyflavanone is an inhibitor of SREBP maturation and lipid synthesis. It is a synthetic analogue of flavanone, with potential for hepatic steatosis and dyslipidemia research.
- Inhibitor of SREBP maturation
- Inhibitor of lipid synthesis
- Synthetic analogue of flavanone
- Potential for hepatic steatosis research
- Potential for dyslipidemia research
Medchemexpress LLC 5,7-Dimethoxyflavone (Standard) | 21392-57-4 | 25 MG
5,7-Dimethoxyflavone (Standard) is the analytical standard of 5,7-Dimethoxyflavone, intended for research and analytical applications. It is a major component of Kaempferia parviflora, known for its anti-obesity, anti-inflammatory, and antineoplastic effects. This compound inhibits cytochrome P450 (CYP) 3As and is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor.
- Analytical standard for research and analytical applications
- Major component of Kaempferia parviflora
- Exhibits anti-obesity effects
- Exhibits anti-inflammatory effects
- Exhibits antineoplastic effects
- Inhibits cytochrome P450 (CYP) 3As
- Potent Breast Cancer Resistance Protein (BCRP) inhibitor
- Used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
Medchemexpress LLC Apigenin | 520-36-5 | 270.24 | 1 G
Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor that inhibits cytochrome P450 2C9 in a purified enzyme system. It demonstrates dose- and time-dependent inhibition of cell proliferation in SGC-7901 cells.
- Competitive CYP2C9 inhibitor with a Ki of 2 μM.
- Inhibits cytochrome P450 2C9 in a purified, reconstituted enzyme system.
- Demonstrates inhibition of cell proliferation in SGC-7901 cells in a dose- and time-dependent manner.
- Achieves growth inhibition rates of 38%, 71%, and 99% at 20, 40, and 80 μM, respectively, on the 7th day.
- Cloning efficiency in SGC-7901 cells treated with 80 μM for 24 and 48 hours was 9.8% and 5%, respectively.
Medchemexpress LLC Chrysin-7-O-glucuronide | 35775-49-6 | 1 MG
Chrysin-7-O-glucuronide is a flavonoid extracted from *Scutellaria baicalensis* that exhibits antioxidant activity. It is intended for research use only.
- Purity: 99.47%
- Source: Flavonoid extracted from *Scutellaria baicalensis*.
- Activity: Antioxidant activity.
- Appearance: Solid, off-white to yellow color.
- Solubility (in vitro): 50 mg/mL (116.18 mM) in DMSO.
- Structure classification: Flavonoids, flavones, phenols, monophenols.
- Initial source: Plants (Leguminosae, Bignoniaceae, Labiatae).
Medchemexpress LLC Engeletin | 572-31-6 | 99.9% | 434.39 g/mol | C21H22O10 | 10 MG
Engeletin is a flavanonol glycoside reported to inhibit NF-κB signaling and to exhibit anti-inflammatory, analgesic, diuretic, and antibacterial effects. It is intended for research use only and has high solubility in DMSO but is essentially insoluble in water.
- Inhibits NF-κB signaling pathway.
- Shows anti-inflammatory and analgesic activity.
- High solubility in DMSO, insoluble in water.
- High purity (99.9%).
- Provided as a small-mass research reagent suitable for in vitro studies.
Medchemexpress LLC Gallocatechin gallate | 5127-64-0 | 1 MG
Gallocatechin gallate is a flavonoids product that can be isolated from the herbs of Celastrus orbiculatus. It is intended for research use only.
- Molecular weight: 458.37
- Formula: C22H18O11
- Appearance: Solid
- Color: White to off-white
- Purity: 98%
- Storage: -20°C, sealed storage, away from moisture and light. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light).
- Structure classification: Flavonoids
- Initial source: Plants, celastraceae, celastrus, Celastrus orbiculatus Thunb.
Medchemexpress LLC (-)-Gallocatechin gallate | 4233-96-9 | MFCD00214298 | 100.0% | 458.37 g/mol | C22H18O11 | 10 MG
(-)-Gallocatechin gallate is a tea-derived polyphenol supplied as an analytical standard for research. It exhibits antioxidant and reported cancer-preventive activity, and has been associated with effects on catechol-O-methyltransferase (COMT). Supplied as a high-purity white to off-white solid for analytical and biological research.
- Tea-derived polyphenol with antioxidant properties.
- Reported cancer-preventive activity and COMT-related effects.
- High purity analytical standard (99.97% LCMS).
- White to off-white solid, suitable for analytical use.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months).