Aminobenzoic acids and derivatives
Sigma Aldrich Tetrakis(Acetonitrile)Copper(I) Hexafluorophosphate
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
TARGETMOL CHEMICALS INC BTTAA 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. BTTAA a Cu(I)-stabilizing ligand performs potently with ubiquitin Glu18AzF. purity: 97%
Medchemexpress LLC N-(Amino-PEG1)-N-bis(PEG2-propargyl) | 2100306-47-4 | 98.0% | 356.46 | 100 MG
N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker primarily utilized in the synthesis of PROTACs. This compound also functions as a click chemistry reagent, containing an alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that have azide groups.
- Peg-based protac linker
- Used in the synthesis of protacs
- Functions as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide group-containing molecules
Medchemexpress LLC 2-Amino-3-iodopyridine | 104830-06-0 | 99.9% | 220.01 | 10 G
2-Amino-3-iodopyridine (3-Iodopyridin-2-amine) can be coupled with formyl derivatives using a copper-catalyzed indole synthesis method, and subsequently, azide analogs can be constructed through copper-mediated conjugated adducts. The nucleophilicity of this compound is lower than that of the corresponding aniline used in indole synthesis. This product is intended for research use only.
- Can be coupled with formyl derivatives.
- Azide analogs can be constructed.
- Solid appearance, off-white to light yellow color.
- Store at 4°C, protected from light.
- Soluble in DMSO at 200 mg/mL.
Medchemexpress LLC 2-Amino-3-iodopyridine | 104830-06-0 | 99.9% | 220.01 | 5 G
2-Amino-3-iodopyridine (3-Iodopyridin-2-amine) can be coupled with formyl derivatives under a copper-catalyzed indole synthesis method, and then constructed azide analogs through copper-mediated conjugated adducts. The nucleophilicity of 2-Amino-3-iodopyridine is lower than that of the corresponding aniline used in the synthesis of indole, which presents a potential obstacle for future synthesis.
- Solubility in DMSO: 200 mg/mL (requires ultrasonic)
- Store at 4°C, protected from light
- When in solvent, store at -80°C for 6 months; -20°C for 1 month (protected from light)
- Targeted as biochemical assay reagents
Medchemexpress LLC Rasagiline (mesylate) | 161735-79-1 | 99.8% | 267.34 | 100 MG
Rasagiline mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor. It is also described as a click chemistry reagent containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor
- IC50s of 4.43 nM for rat brain MAO B activity
- IC50s of 412 nM for rat brain MAO A activity
- Click chemistry reagent
- Capable of copper-catalyzed azide-alkyne cycloaddition
- Increases proliferation rates of certain cell lines
- Neuroprotective in a transgenic model of multiple system atrophy
Medchemexpress LLC N-(Amino-PEG1)-N-bis(PEG2-propargyl) | 2100306-47-4 | 98.0% | 356.46 | 25 MG
N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is a click chemistry reagent, containing an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Azide groups
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
Medchemexpress LLC 7-Amino-4-methylcoumarin | 26093-31-2 | 99.9% | 500 MG
7-Amino-4-methylcoumarin belongs to the coumarin class and can be isolated from the endophytic fungus Xylaria sp., exhibiting broad-spectrum antibacterial activity. This compound is commonly used as an important laser dye that emits in the blue region. It is capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength for 7-Amino-4-methylcoumarin is 351 nm, and its emission wavelength is 430 nm.
- Used as an important laser dye that emits in the blue region.
- Capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides.
- Utilized in tissue pathology analysis.
- Used for enzyme activity measurement.
- Suitable for copper ion detection.
- Exhibits broad-spectrum antibacterial activity.
Medchemexpress LLC N-(Amino-PEG1)-N-bis(PEG2-propargyl) | 2100306-47-4 | 98.0% | 356.46 | 50 MG
N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This compound acts as a click chemistry reagent, featuring an alkyne group that can engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. PROTACs themselves consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. PROTACs function by leveraging the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Utilized in the synthesis of PROTACs
- Acts as a click chemistry reagent
- Features an alkyne group for copper-catalyzed azide-alkyne cycloaddition
- Engages with molecules containing azide groups
- PROTACs leverage the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
Medchemexpress LLC 3-hydroxypicolinic acid | 874-24-8 | MFCD00006294 | 99.9% | 139.11 g/mol | C6H5NO3 | 25g
3-Hydroxypicolinic acid is a matrix 3-Hydroxypicolinic acid coordinates with metal ions such as copper to form complexes with cytotoxic and antimycobacterial activity 3-Hydroxypicolinic acid is used for the analysis of oligodeoxynucleotides in matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) 3-Hydroxypicolinic acid is useful for nucleic acid analysis and anti-tuberculosis compound development[1][2][3]
TARGETMOL CHEMICALS INC TYROSINASE-IN-2 5MG
Also available in 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Tyrosinase-IN-2 (compound 67) is a potent tyrosinase inhibitor. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-2 has the potential for the research of skin whitening agents and food preservatives [1]. purity: 98%
Medchemexpress LLC 7-Amino-4-methylcoumarin | 26093-31-2 | 1 G
7-Amino-4-methylcoumarin, a compound of the coumarin class, can be isolated from the endophytic fungus *Xylaria sp.* It exhibits broad-spectrum antibacterial activity and is commonly used as an important laser dye that emits in the blue region. It is capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides.
- Utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection.
- Excitation wavelength: 351 nm
- Emission wavelength: 430 nm
- Exhibits broad-spectrum antibacterial activity.
Medchemexpress LLC A-908292 | 903886-95-3 | 99.9% | 360.43 | 1 ML
A-908292 is a potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor with an IC50 of 23 nM for human ACC2. It is used in research on fatty acid metabolism and is also a click chemistry reagent.
- Contains an Alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reduces serum glucose and triglyceride levels in ob/ob mice
- Markedly reduces plasma triglyceride levels in ACC2 knockout mice
- Stimulates the PPAR-α-dependent signaling pathway in rats
Apexbio Technology LLC 3-Hydroxypicolinic acid 874-24-8 500mg
3-Hydroxypicolinic acid (CAS 874-24-8) is a pyridine-based small molecule characterized by its capacity to chelate metal ions particularly copper(II) This ligand is commonly employed in the synthesis of metal coordination complexes which have been investigated for their ability to modulate biological activity through interactions involving metal ions and biomolecules Studies on such complexes indicate potential anti-tuberculosis properties attributed to their influence on metal-mediated biochemical pathways 3-Hydroxypicolinic acid is thus of interest in the fields of coordination chemistry and drug discovery supporting research into the bioactivity and molecular mechanisms of metal-based therapeutics
Apexbio Technology LLC 3-Hydroxypicolinic acid 874-24-8 1g
3-Hydroxypicolinic acid (CAS 874-24-8) is a pyridine-based small molecule characterized by its capacity to chelate metal ions particularly copper(II) This ligand is commonly employed in the synthesis of metal coordination complexes which have been investigated for their ability to modulate biological activity through interactions involving metal ions and biomolecules Studies on such complexes indicate potential anti-tuberculosis properties attributed to their influence on metal-mediated biochemical pathways 3-Hydroxypicolinic acid is thus of interest in the fields of coordination chemistry and drug discovery supporting research into the bioactivity and molecular mechanisms of metal-based therapeutics
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