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Filtered Search Results
Medchemexpress LLC HY-12248 10mg Medchemexpress, Telaglenastat CAS:1439399-58-2 Purity:>98%
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Medchemexpress, HY-12248 10mg Telaglenastat CAS:1439399-58-2 Telaglenastat (CB-839) is a first-in-class, selective, reversible and orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2. The IC50s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat inudces autophagy and has antitumor activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-15392 5mg Medchemexpress, Chroman 1 CAS:1273579-40-0 Purity:>98%
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Medchemexpress, HY-15392 5mg Chroman 1 CAS:1273579-40-0 Chroman 1 dihydrochloride is a highly potent ROCK2 inhibitor, with an IC50 of 1 nM. Chroman 1 dihydrochloride also shows inhibitory activities against MRCK, with an IC50 of 150 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-50696 10mg Medchemexpress, Nutlin-3 CAS:548472-68-0 Purity:>98%
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Medchemexpress, HY-50696 10mg Nutlin-3 CAS:548472-68-0 Nutlin-3 is a commercial available p53-MDM2 inhibitor, with Ki of 90 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-13311 50mg Medchemexpress, Infigratinib CAS:872511-34-7 Purity:>98%
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Medchemexpress, HY-13311 50mg Infigratinib CAS:872511-34-7 Infigratinib (BGJ-398; NVP-BGJ398) is a potent inhibitor of the FGFR family with IC50s of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-16069 50mg Medchemexpress, Tucatinib CAS:937263-43-9 Purity:>98%
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Medchemexpress, HY-16069 50mg Tucatinib CAS:937263-43-9 Tucatinib (Irbinitinib; ARRY-380; ONT-380) is a potent and selective HER2 inhibitor with an IC50 of 8 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-50709 10mg Medchemexpress, A939572 CAS:1032229-33-6 Purity:>98%
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Medchemexpress, HY-50709 10mg A939572 CAS:1032229-33-6 A939572 is a potent, and orally bioavailable stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM and 37 nM for mSCD1 and hSCD1, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-50202 10mg Medchemexpress, Etomoxir CAS:124083-20-1 Purity:>98%
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Medchemexpress, HY-50202 10mg Etomoxir CAS:124083-20-1 Etomoxir ((R)-(+)-Etomoxir) is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 1435469-45-6 | Medchem Express | MPO-IN-3 | 5mg | 758391410 | HY-145197 | 371.88 | C16H22ClN3O3S
Medchem Express | YU238259 | 5mg | 446270656 | HY-19977 | 1943733-16-1 | MFCD30532769 | 459.950 | C22H22ClN3O4S
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Medchemexpress LLC HY-114379 10mg Medchemexpress, AS2717638 CAS:2148339-28-8 Purity:>98%
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Medchemexpress, HY-114379 10mg AS2717638 CAS:2148339-28-8 AS2717638 is an oral active and selective lysophosphatidic acid receptor 5 (LPA5) antagonist, with an IC50 of 38 nM for hLPA5. AS2717638 also significantly improves PGE2-, PGF2α-, and AMPA-induced allodynia. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-114403 10mg Medchemexpress, VU6012962 CAS: Purity:>98%
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Medchemexpress, HY-114403 10mg VU6012962 CAS: VU6012962 is an orally bioavailable and CNS-penetrant metabotropic glutamate receptor 7 negative allosteric modulator (mGlu7 NAM) with an IC50 of 347 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Matrix Scientific (3,4-DIMETHOXYPHENYL)ACETIC-25
(3,4-dimethoxyphenyl)acetic Acid Mf C10h12o4 Mw 196.20 Cas 93-40-3 Mdl MFCD00004335
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Medchemexpress LLC HY-108606 10mg Medchemexpress, PI-828 CAS:942289-87-4 Purity:>98%
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Medchemexpress, HY-108606 10mg PI-828 CAS:942289-87-4 PI-828 is a dual PI3K and casein kinase 2 (CK2) inhibitor with IC50s of 173 nM, 149 nM, and 1127 nM for p110α, CK2, and CK2α2 in lipid kinase assay, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC GSK2945 hydrochloride | 00-00-0 | 99.7% | 457.80 g/mol | C20H19Cl3N2O2S | 5 MG
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GSK2945 hydrochloride is the hydrochloride salt of a small-molecule antagonist of the nuclear receptor Rev-erbα, supplied for preclinical research. It has reported EC50 values of 21.5 μM (mouse) and 20.8 μM (human) and has been used to increase CYP7A1 levels and modulate cholesterol metabolism.
- High chemical purity (99.7%).
- Solid form suitable for storage at 4°C; in solution store under nitrogen at -80°C (6 months) or -20°C (1 month).
- Soluble in DMSO (~20.83 mg/mL); in vivo formulations and protocols are available for suspension or clear solution preparations.
- Activity: Rev-erbα antagonist with reported EC50 around 21 μM in cell-based assays.
- Provided for research use with supporting assay and formulation data.
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Medchemexpress LLC HG-7-85-01-NH2 | 1258391-29-5 | MFCD34646287 | 98.1% | C27H27F3N6OS | 10MG
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HG-7-85-01-NH2 is a research ligand derived from the ABL inhibitor HG-7-85-01, designed to act as the target-protein-binding moiety in SNIPER constructs for targeted protein degradation studies. It is supplied as a characterized, high-purity compound with manufacturer-recommended solubility and storage conditions for preclinical research use.
- High purity (98.1%).
- Molecular formula C27H27F3N6OS; molecular weight 540.6.
- Soluble in DMSO at 125 mg/mL (231.22 mM) with ultrasonic aid and pH adjustment.
- Powder stable at -20°C for up to 3 years; in solvent stable at -80°C for 6 months.
- Supplied in multiple small research quantities.
- Intended for synthesis of SNIPER molecules and targeted degradation assays.
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SELLECK CHEMICAL LLC SBI-0206965 10MM 1ML IN DMSO
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NC2601197 SBI-0206965 10MM 1ML IN DMSO
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