Phenylhydrazines
Medchemexpress LLC 2-Bromo-4-methylphenol | 6627-55-0 | MFCD00002151 | 99.3% | 187.03 g/mol | C7H7BrO | 50 G
2-Bromo-4-methylphenol is a brominated phenol compound used as a biochemical reagent and intermediate in organic synthesis. It is employed in research applications and chemical synthesis where a functionalized aromatic building block is required. The material is supplied as a high-purity solid with supporting technical and safety documentation for laboratory use.
- High purity suitable for research applications.
- Useful intermediate for organic synthesis.
- Acts as a building block for functionalized aromatic compounds.
- Supplied as a stable solid for storage and handling.
- Includes technical data sheet and safety data sheet for safe use.
Medchemexpress LLC Proparacaine hydrochloride | 5875-06-9 | C16H27ClN2O3 | 1 G
Proparacaine hydrochloride, also known as Proxymetacaine Hydrochloride, is a derivative of lidocaine. It exhibits immunomodulatory and glucocorticomimetic activities.
- Exhibits immunomodulatory and glucocorticomimetic activities
- Demonstrates dose- and time-dependent cytotoxicity to HCS cells in vitro
- Induces apoptosis and G1 phase arrest in HCS cells
- Activates caspase-2, -3, and -9 pathways
- Disrupts mitochondrial transmembrane potential
- Modulates Bcl-xL and Bax expression
- Increases cytoplasmic cytochrome C and apoptosis-inducing factor
- Reduces nasal symptoms in allergic rhinitis mouse models
Medchemexpress LLC 2,6-Pyridinedicarboxamide, 4-(2-aminoethoxy)-N2,N6-bis[4-(2-aminoethoxy)-2-quinolinyl]-, hydrochloride (1:5) | 1781882-65-2 | C31H37Cl5N8O5 | 50 MG
Pyridostatin hydrochloride is a G-quadruplex DNA stabilizing agent that targets DNA and RNA G4s in cells. It promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. This compound targets the proto-oncogene Src, reducing SRC protein levels and SRC-dependent cellular motility in human breast cancer cells. It is suitable for research use only.
- Selective G-quadruplex DNA-binding small molecule
- Induces cell cycle arrest in over 60 different cancer cell lines
- Causes neurite retraction and synaptic loss
- Downregulates BRCA1 protein at the transcriptional level
Medchemexpress LLC Pyridostatin hydrochloride | 1781882-65-2 | C31H37Cl5N8O5 | 5 MG
Pyridostatin hydrochloride is a G-quadruplex DNA stabilizing agent that targets DNA and RNA G4s in cells. It promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. This selective G-quadruplex DNA-binding small molecule also targets the proto-oncogene Src, reducing SRC protein levels and cellular motility in human breast cancer cells.
- G-quadruplex DNA stabilizing agent (Kd=490 nM)
- Targets DNA and RNA G4s in cells
- Promotes growth arrest in human cancer cells
- Induces replication- and transcription-dependent DNA damage
- Targets proto-oncogene Src
- Reduces SRC protein levels and cellular motility
- Causes neurite retraction, synaptic loss, and neuronal death
- Induces formation of DNA DSBs
- Downregulates BRCA1 protein at transcriptional level
eMolecules 97108-50-4 | 2,5-Difluorophenylhydrazine | MFCD00013384 | 5g
Combi-Blocks | 2,5-Difluorophenylhydrazine | 5g | 482935591 | OR-2224 | 95.000 | 97108-50-4 | MFCD00013384 | 144.125 | C6H6F2N2
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