Aminophenols
eMolecules 13811-12-6 | 3-(3,5-Dibromo-4-hydroxyphenyl)propanoic acid | Apollo Scientific | MFCD00816760 | 323.968 | C9H8Br2O3 | 95.000 | OC(=O)CCc1cc(Br)c(O)c(Br)c1 | 1g | 562430610
3-(3,5-Dibromo-4-hydroxyphenyl)propanoic acid | Apollo Scientific | 13811-12-6 | MFCD00816760 | 323.968 | C9H8Br2O3 | 95.000 | OC(=O)CCc1cc(Br)c(O)c(Br)c1 | 1g | 562430610
Medchemexpress LLC Sotorasib-d7 | 2296729-00-3 | 98.9% | 567.64 | 10 MG
Sotorasib-d7 is a deuterium-labeled Sotorasib and a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. It irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state, leading to the regression of KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC).
- Deuterium-labeled Sotorasib.
- First-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor.
- Irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state.
- Leads to the regression of KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC).
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC di-Pal-MTO | 1349197-90-5 | 98.4% | 917.27 | 5 MG
di-Pal-MTO is a palm oil-based lipid created by combining the anticancer agent mitoxantrone (MTO) with palmitoleic acid. When formulated into nanoparticles with mono-Pal-MTO in a 1:1 molar ratio, it demonstrates effective siRNA cell delivery and enhanced anticancer activity. This combination has been shown to significantly reduce tumor cell viability by 81% and tumor size by 83% in vitro, outperforming Lipofectamine 2000-mediated transfection.
- Palm oil-based lipid, combining mitoxantrone (MTO) and palmitoleic acid.
- Effective siRNA cell delivery, enhanced anticancer activity.
- Forms nanoparticles (1:1 molar ratio with mono-Pal-MTO) for effective siRNA delivery.
- Enhances in vitro antitumor activity, reducing tumor cell viability by 81% and tumor size by 83%.
Medchemexpress LLC BN82002 hydrochloride | 1049740-43-3 | 99.4% | 395.88 | 10 MG
BN82002 hydrochloride is a potent, selective, and irreversible inhibitor of the CDC25 phosphatase family. It demonstrates significant inhibitory activity against various CDC25 isoforms including CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat, with IC50 values ranging from 2.4 to 6.3 μM. This compound also exhibits high selectivity, showing approximately 20-fold greater inhibition over CD45 tyrosine phosphatase.
- Potent and selective CDC25 phosphatase inhibitor
- Inhibits CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat
- Demonstrates approximately 20-fold greater selectivity over CD45 tyrosine phosphatase
- Irreversible inhibitor
Medchemexpress LLC Disodium cantharidin | 1465-77-6 | 95.0% | 258.18 g·mol⁻1 | C10H12Na2O5 | 5 MG
Disodium cantharidin is the disodium salt of cantharidin and functions as a selective inhibitor of protein phosphatases PP2A and PP1. Supplied as a solid research reagent (5 mg), it is used in biochemical and cell-based studies to probe phosphatase activity, cell signaling, and apoptosis. For research use only.
- Selective PP2A and PP1 inhibitor, useful for signaling studies.
- Reported activity: PP2A IC50 ≈ 50 nM, PP1 IC50 ≈ 600 nM.
- High purity solid, typically 95% by vendor specification.
- Small package sizes suitable for screening and method development.
- Sodium salt form with formula C10H12Na2O5 and molecular weight 258.18 g·mol⁻1.
Medchemexpress LLC V-0219 hydrochloride | 2922283-73-4 | MFCD35062234 | 99.4% | 446.89 g/mol | C20H26ClF3N4O2 | 5 MG
V-0219 hydrochloride is the hydrochloride salt of an orally active positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R). It is supplied as a solid research reagent for in vitro and preclinical studies of GLP-1R modulation and metabolic disease models.
- High purity (99.39%) for reproducible experimental results.
- Solid form, convenient to weigh and store.
- Good DMSO solubility (100 mg/mL) for assay preparation.
- Suitable for in vitro and preclinical screening applications.
- Storage guidance provided for sealed, moisture-free conditions and solvent storage at -80 °C (long term) or -20 °C (short term).
Medchemexpress LLC NS-3-008 hydrochloride | 1172854-54-4 | 99.7% | 1 ML
NS-3-008 hydrochloride is a small-molecule transcriptional inhibitor of G0/G1 switch 2 (G0s2) with a reported IC50 of 2.25 μM. It is supplied as a concentrate solution for research use and as solids for analytical or in vivo studies. Typical applications include biochemical assays and disease-model investigations such as chronic kidney disease research.
- Transcriptional inhibitor of G0s2 with IC50 ≈ 2.25 μM.
- Available as 10 mM solution in DMSO (1 mL) and as solid packs for flexibility in workflows.
- High purity (99.7%) suitable for biochemical, cellular, and in vivo studies.
- Off-white to light yellow solid with molecular formula C14H24ClN3 and MW 269.81 g·mol⁻¹.
- Supplied with characterization data to support reproducibility in research.
Medchemexpress LLC Bestatin-d7 (hydrochloride) | 97.7% | 1 MG
Bestatin-d7 (hydrochloride) is a deuterium-labeled version of Bestatin (hydrochloride). Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, primarily utilized in cancer research.
- Deuterium labeled compound
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase
Medchemexpress LLC CSRM617 hydrochloride | 1353749-74-2 | 100.0% | 100 MG
CSRM617 hydrochloride is the hydrochloride salt of a selective small-molecule inhibitor of the transcription factor ONECUT2, supplied as a white to off-white solid for research use.
- Selective inhibitor of ONECUT2 transcription factor.
- Hydrochloride salt, white to off-white solid.
- Purity 99.97%.
- Molecular weight 291.69 g/mol.
- Soluble in DMSO (100 mg/mL; ultrasonic assistance recommended).
- Store sealed, away from moisture; in solvent: -80°C (6 months), -20°C (1 month).
- For research use only; not for human use.
eMolecules 14452-34-7 | 2,4-Dimethyl-6-nitrophenol | MFCD00191633 | 1g
Ambeed | 2-(4-(Trifluoromethoxy)phenyl)ethanol | 1g | 525055889 | A145273 | 196811-90-2 | MFCD08276850 | 206.164 | C9H9F3O2
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Medchemexpress LLC Ozanimod (hydrochloride) | 1618636-37-5 | 98.1% | 1 ML
Ozanimod hydrochloride 10 mM in DMSO (1 mL) is a ready-to-use research reagent for studying sphingosine 1-phosphate (S1P) receptor modulation in preclinical and biochemical assays. Supplied as a solution to improve handling and reproducibility. For research use only; not for human use.
- Ready-to-use 10 mM solution in DMSO.
- Supplied as a 1 mL aliquot for small-scale experiments.
- Listed purity 98.1% for consistent experimental results.
- Molecular weight 440.92 g/mol and formula C23H25ClN4O3.
- Intended for research use only; not for clinical or human use.
![Medchemexpress LLC 7-[3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propoxy]-1H-quinolin-2-one hydrochloride | 1329509-60-5 | 99.0% | 427.97 g·mol⁻¹ | C24H30ClN3O2 | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000241642.png-250.jpg)
Medchemexpress LLC 7-[3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propoxy]-1H-quinolin-2-one hydrochloride | 1329509-60-5 | 99.0% | 427.97 g·mol⁻¹ | C24H30ClN3O2 | 1 MG
OPC 4392 hydrochloride is a small-molecule dopamine receptor modulator used in preclinical pharmacology research. It functions as a presynaptic dopamine autoreceptor agonist and a postsynaptic D2 receptor antagonist, and has been applied in animal studies to reverse reserpine-induced dopamine depletion and reduce apomorphine-induced behaviors.
- Acts as presynaptic dopamine autoreceptor agonist and postsynaptic D2 antagonist.
- Demonstrated efficacy in reversing reserpine-induced dopamine depletion in animal studies.
- Inhibits apomorphine-induced stereotypic and climbing behaviors in rodent models.
- High purity (98.99%) suitable for research applications.
- White to off-white solid, convenient for handling and formulation.
- Recommended sealed storage away from moisture; in solvent store at -80°C for long-term preservation.
Medchemexpress LLC SKI-I 25mg | 306301-68-8 | 25 MG
SKI-I is a research-grade small-molecule inhibitor of sphingosine kinase used in biochemical and cell-based assays to study sphingolipid signaling and apoptosis. Not for human use.
- Potent sphingosine kinase inhibitor (IC50 1.2 μM for ST-hSK).
- Also inhibits hERK2 (IC50 11 μM).
- Induces apoptosis in multiple tumor cell lines.
- High purity (99.14%).
- Soluble in DMSO at 100 mg/mL for in vitro applications.
Medchemexpress LLC SKI-I 10mg | 306301-68-8 | 406.44 | C25H18N4O2 | 10 MG
SKI-I is a small-molecule sphingosine kinase inhibitor supplied as a 10 mg research-grade solid for laboratory use. It inhibits human sphingosine kinase with reported IC50 ≈ 1.2 μM and shows additional activity against hERK2; reported purity and storage conditions support reproducible experimental use.
- High reported purity (99.14%).
- Off-white to light yellow solid; convenient 10 mg quantity for assay development.
- Soluble in DMSO at 100 mg/mL; suitable for in vitro use and formulatable for in vivo studies.
- Storage: powder at 4°C protected from light; aliquots in solvent stable at -80°C for up to 6 months.
- Demonstrated cytotoxicity against multiple human cancer cell lines at low micromolar concentrations.