Aminophenols
Medchemexpress LLC PF-8380 hydrochloride | 2070015-01-7 | 98.6% | 514.79 g/mol | C22H22ClN2O5S | 5 MG
PF-8380 hydrochloride is a small-molecule autotaxin (ATX) inhibitor supplied as a research reagent. It demonstrates potent inhibition in isolated enzyme assays and measurable activity in human whole blood, and is intended for laboratory research use only.
- Potent autotaxin inhibitor; IC50 2.8 nM in isolated enzyme assay.
- Active in human whole blood with IC50 ~101 nM.
- Molecular weight 514.79 g/mol and formula C22H22ClN2O5S.
- High purity (98.6%), suitable for biochemical and cellular assays.
- Available in small research pack sizes (1 mg, 5 mg, 10 mg).
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC NPS-2143 hydrochloride | 324523-20-8 | MFCD04113010 | 100.0% | 445.38 | C24H26Cl2N2O2 | 1 ML
NPS-2143 hydrochloride is a selective and potent calcium-sensing receptor (CaSR) antagonist used as a calcilytic research tool to modulate intracellular calcium signaling and parathyroid hormone secretion. It is supplied as a white to off-white solid and is available pre-formulated as a 10 mM solution in DMSO for laboratory use.
- Selective calcium-sensing receptor antagonist (IC50 = 43 nM).
- Useful for studies of CaSR signaling and parathyroid hormone release.
- Available as solid and as a 10 mM solution in DMSO for convenience.
- High purity suitable for research applications.
- White to off-white solid form for easy handling and storage.
Medchemexpress LLC Metixene hydrochloride hydrate | 7081-40-5 | ≥95.0% | 5MG
Metixene hydrochloride hydrate | 7081-40-5 | ≥95.0% | 5MG
![Medchemexpress LLC 2-[[(3R)-3-(4-fluorophenyl)-3-(4-phenylphenoxy)propyl]-methylamino]acetic acid hydrochloride | 200006-08-2 | MFCD09971056 | 98.2% | 429.91 | C24H25ClFNO3 | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000239773.png-250.jpg)
Medchemexpress LLC 2-[[(3R)-3-(4-fluorophenyl)-3-(4-phenylphenoxy)propyl]-methylamino]acetic acid hydrochloride | 200006-08-2 | MFCD09971056 | 98.2% | 429.91 | C24H25ClFNO3 | 1 MG
ALX-5407 hydrochloride is the hydrochloride salt of a selective glycine transporter 1 (GlyT1) inhibitor used in preclinical research to increase extracellular glycine and probe GlyT1 biology. It is provided as a high-purity research chemical for in vitro and in vivo studies.
- Selective glycine transporter 1 inhibitor with high potency (IC50 ≈ 3 nM).
- Hydrochloride salt form for improved solubility.
- High purity (98.2%) suitable for research applications.
- Available in small quantities for dose-response and pilot studies.
- Molecular weight 429.91 and formula C24H25ClFNO3 for precise calculations.
Medchemexpress LLC Metixene hydrochloride hydrate | 7081-40-5 | 99.9% | 1 ML
Metixene hydrochloride hydrate is supplied as a 10 mM solution in DMSO for research use. It is the hydrochloride salt of metixene, an anticholinergic and antiparkinsonian agent, provided in a 1 mL vial.
- Ready-to-use 10 mM solution in DMSO.
- Compact 1 mL vial for small-scale assays.
- High purity suitable for research applications.
- Molecular formula C20H26ClNOS, molecular weight 363.94 g/mol.
- Suitable for in vitro pharmacology and receptor studies.
Medchemexpress LLC Ozanimod hydrochloride | 1618636-37-5 | 98.1% | 25MG
Ozanimod hydrochloride | 1618636-37-5 | 98.1% | 25MG
Medchemexpress LLC Tecalcet hydrochloride | 177172-49-5 | MFCD16038895 | 99.7% | 340.29 g/mol | C18H23Cl2NO | 1 ML
Tecalcet hydrochloride is an orally active calcimimetic that allosterically and positively modulates the calcium-sensing receptor (CaSR). It is provided for research use in solution and solid forms and is commonly used in in vitro pharmacology and calcium-signaling studies.
- Orally active calcimimetic that modulates the calcium-sensing receptor.
- Suitable for in vitro pharmacology and CaSR signaling studies.
- Available as a 10 mM solution in DMSO (1 mL) and as solid quantities for formulation flexibility.
- High chemical purity (≈99.7%) for reliable experimental results.
- Molecular weight 340.29 g/mol and molecular formula C18H23Cl2NO.
Medchemexpress LLC BIIL-260 hydrochlori 10mM 1mL | 192581-24-1 | 1 ML
Biil-260 hydrochloride is a potent leukotriene B4 (LTB4) receptor antagonist used in research to investigate inflammatory signaling pathways. It is typically supplied at high purity and commonly provided as a 10 mM solution in DMSO for in vitro applications.
- Potent LTB4 receptor antagonist
- High purity (99.4%)
- Molecular weight 503.03 g/mol
- Supplied as a 10 mM solution in DMSO, 1 mL
- Appearance: solid, white to off-white
- Storage: solids sealed at 4°C; in solution store at -80°C for long term
Medchemexpress LLC RS 67333 hydrochloride | 168986-60-5 | MFCD00938576 | 99.7% | 389.36 g/mol | C19H30Cl2N2O2 | 1 ML
RS 67333 hydrochloride is a research reagent that functions as a potent, selective partial agonist of the 5-HT4 (serotonin 4) receptor. It is supplied as a ready-to-use 10 mM solution in DMSO (1 mL) and in multiple solid pack sizes for use in pharmacology and neuroscience studies, including neuroprotection and Alzheimer's disease research. CAS: 168986-60-5; purity ~99.7%.
- Potent, selective 5-HT4 receptor partial agonist.
- Offered as 10 mM solution in DMSO (1 mL) and multiple solid sizes.
- High listed purity (~99.7%).
- Suitable for pharmacology and neuroscience research applications.
- Provided with datasheet, certificate of analysis, and safety data sheet.
Medchemexpress LLC 4-tert-Octylphenol | 140-66-9 | 99.7% | 1000 G
4-tert-Octylphenol is an endocrine-disrupting chemical and an estrogenic agent, also a biodegradation product of non-ionic surfactants alkylphenol polyethoxylates. It induces apoptosis in neuronal progenitor cells in offspring mouse brain, reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), which leads to a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice.
- Endocrine-disrupting chemical
- Estrogenic agent
- Biodegradation product of non-ionic surfactants alkylphenol polyethoxylates
- Induces apoptosis in neuronal progenitor cells in offspring mouse brain
- Reduces neuronal progenitor proliferation by affecting BrdU, Ki67, and phospho-histone H3
- Disrupts brain development and behavior in mice
- Promising for research of immune response, neuro-related diseases and ethology
![Medchemexpress LLC Benzamide, 2-chloro-5-[3-[(3-hydroxypropyl)amino]propyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethy-1)- | 345303-91-5 | 98.2% | 455.46 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000385590-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Benzamide, 2-chloro-5-[3-[(3-hydroxypropyl)amino]propyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethy-1)- | 345303-91-5 | 98.2% | 455.46 | 25 MG
AZD9056 hydrochloride is a selective and orally active inhibitor of P2X7, a receptor that plays a significant role in inflammatory and pain-causing diseases. This compound is intended for research use only.
- Blocks P2X7 receptors with an IC50 of 11.2 nM in HEK-hP2X7 cell lines, demonstrating high selectivity for the P2X7 receptor.
- Exhibits an inhibitory effect (IC50=1-3 μM) in mouse microglia BV2 cells.
- Weakly inhibits BCRP-mediated transport of methotrexate (IC50=92 μM).
- Displays pain-relieving and anti-inflammatory effects.
- Reverses the upregulated expression of interleukin (IL)-1β, IL-6, tumor necrosis factor-α (TNF-α), matrix metalloproteinase-13 (MMP-13), substance P (SP), and prostaglandin E2 (PGE2) induced by MIA in cartilage tissues.
Medchemexpress LLC Acetaminophen (Standard) | 103-90-2 | 100.0% | C8H9NO2 | 25 MG
Acetaminophen (Standard) is an analytical standard of Acetaminophen, primarily used for research and analytical applications. Also known as Paracetamol or 4-Acetamidophenol, it is a selective cyclooxygenase-2 (COX-2) inhibitor and a widely recognized antipyretic and analgesic agent. It also acts as a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
- Analytical standard for research and analytical applications
- Reference standard for assays
- Suitable for HPLC, GC, and MS experiments
- Functions as a selective cyclooxygenase-2 (COX-2) inhibitor
- Widely used as an antipyretic and analgesic agent
- Acts as a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor
Medchemexpress LLC LDC4297 hydrochloride | 2319747-14-1 | MFCD34676707 | 98.2% | 468.98 | C23H29ClN8O | 5 MG
LDC4297 hydrochloride is a small-molecule research reagent that selectively inhibits cyclin-dependent kinase 7 (CDK7). Supplied as the hydrochloride salt for laboratory use only, it is intended for cell-signaling and antiviral research and is available in both solid and solution formats.
- Selective CDK7 inhibition for target-specific studies.
- Suitable for in vitro cell-based assays and mechanistic studies.
- Available in multiple sizes including small solid quantities and DMSO solution.
- High purity suitable for research applications.
- Supplied as the hydrochloride salt for improved stability and solubility.