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Filtered Search Results
Medchemexpress LLC Pararosaniline hydrochloride | 569-61-9 | 00001657 | 97.3% | 323.83 g/mol | C19H18ClN3 | 10 G
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Pararosaniline hydrochloride is a basic red dye provided as a solid powder for laboratory staining and analytical applications. It is used as a biological stain and in Schiff reagent formulations, exhibits pH-responsive color behavior, and is supplied at high purity in small pack sizes suitable for bench-top use.
- Basic red dye for histological and cytological staining.
- pH-responsive color change useful in analytical assays.
- Solid powder form, easy to weigh and dissolve.
- High purity suitable for laboratory applications.
- Available in small pack sizes for routine use.
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Medchemexpress LLC Minocycline (hydrochloride) (standard) | 13614-98-7 | 99.5% | 493.94 | 100 MG
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Minocycline (hydrochloride) (standard) | 13614-98-7 | 99.5% | 493.94 | 100 MG
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Medchemexpress LLC Benzenecarboximidamide, hydrochloride, hydrate | 206752-36-5 | 99.6% | C7H8N2·ClH·xH2O | 5 G
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Benzamidine hydrochloride hydrate is a reversible competitive inhibitor of trypsin-like serine proteases used in enzymatic assays and protease inhibition studies. It is supplied as a white to light-yellow solid with high purity for biochemical research.
- Reversible competitive inhibitor of trypsin-like serine proteases.
- High purity: 99.58%.
- White to light-yellow solid physical form.
- Available in common lab pack sizes, including 5 g.
- Intended for research use in enzymology and protease inhibition assays.
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Medchemexpress LLC Cycloguanil hydrochloride | 152-53-4 | 99.9% | 25 MG
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Cycloguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 10.8 μM against human DHFR. It functions by blocking the folate metabolic pathway, which affects nucleotide synthesis and interferes with DNA replication. It inhibits DHFR in Plasmodium, making it relevant for malaria research. Additionally, it exhibits anticancer activity by potently inhibiting DHFR in human cancer cells and blocking the transcriptional activity of STAT3.
- Inhibits dihydrofolate reductase (DHFR)
- Blocks the folate metabolic pathway
- Interferes with DNA replication and nucleotide synthesis
- Relevant for malaria research through Plasmodium DHFR inhibition
- Exhibits anticancer activity in human cancer cells
- Blocks transcriptional activity of STAT3
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Medchemexpress LLC Dronedarone Hydrochloride | 141625-93-6 | 99.99% | C31H45ClN2O5S | 200 MG
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Dronedarone Hydrochloride is a non-iodinated amiodarone derivative that acts as a multichannel blocker for atrial fibrillation by inhibiting Na+, K+, and Ca2+ currents.
- Inhibits Na+, K+, and Ca2+ currents
- Acts as a multichannel blocker for atrial fibrillation
- Potently inhibits acetylcholine-activated K+ current
- Blocks IKr (IC50=3 μM) and ICa-L (IC50=0.18 μM) under whole-cell patch clamp
- Exhibits state-dependent inhibition of fast Na+ channel current
- Reduces incidence of ventricular fibrillation in rats
- Inhibits carotid artery thrombus formation in vivo
- Impairs thrombin- and collagen-induced platelet aggregation
- Reduces expression of plasminogen activator inhibitor-1 (PAI1)
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Medchemexpress LLC L-methioninamide hydrochloride | 16120-92-6 | MFCD00039084 | 99.2% | 184.69 g/mol | C5H13ClN2OS | 10 G
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L-methioninamide hydrochloride is the hydrochloride salt of L-methioninamide, a methionine analogue reported to inhibit methionyl-tRNA synthetase. It is supplied for research use and is available as solid material or as ready-to-use DMSO solutions for biochemical and biological studies.
- Acts as a methionyl-tRNA synthetase inhibitor.
- Available as solid and as 10 mM DMSO solution formats.
- High purity suitable for analytical and biological research.
- Molecular weight 184.69 g/mol; formula C5H13ClN2OS.
- For research use only; not for human or clinical use.
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Medchemexpress LLC Phenazopyridine hydrochloride | 136-40-3 | 99.6% | 1 ML
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Phenazopyridine hydrochloride is a competitive SARM1 inhibitor (IC50 145 μM) and a TRPM8 antagonist. It has local anesthetic and analgesic effects, and can promote neuronal differentiation. This product is used to relieve painful symptoms of conditions like cystitis and urethritis, and in the study of traumatic brain injury, peripheral neuropathy, and neurodegenerative diseases.
- Competitive SARM1 inhibitor (IC50 145 μM)
- TRPM8 antagonist
- Exhibits local anesthetic and analgesic effects
- Relieves painful symptoms of cystitis and urethritis
- Promotes neuronal differentiation
- Used in research for traumatic brain injury, peripheral neuropathy, and neurodegenerative diseases
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Medchemexpress LLC Metipranolol hydrochloride | 36592-77-5 | 99.9% | 345.86 | 50 MG
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Metipranolol hydrochloride is a non-selective β adrenergic receptor blocking agent. It is used systemically for the treatment of arterial hypertension and topically for the management of glaucoma. This product is for research use only.
- Non-selective β adrenergic receptor blocking agent.
- Used systemically for the treatment of arterial hypertension.
- Used topically for the management of glaucoma.
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Medchemexpress LLC (R)-viloxazine hydrochloride | 56287-63-9 | MFCD18379655 | 99.1% | 273.76 g/mol | C13H20ClNO3 | 1MG
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(R)-Viloxazine hydrochloride is the less active R-isomer of viloxazine hydrochloride, a norepinephrine reuptake inhibitor investigated for antidepressant activity. Supplied as a high-purity white to off-white solid for laboratory research, it is suitable for formulation and preclinical studies and is soluble in DMSO at useful concentrations.
- High purity: 99.08% (supplier reported)
- Molecular formula: C13H20ClNO3
- Molecular weight: 273.76 g/mol
- White to off-white solid form
- Recommended DMSO solubility up to 25 mg/mL
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month)
- Available in small milligram research sizes
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Medchemexpress LLC Saxagliptin (hydrochloride) | 709031-78-7 | 99.7% | 351.87 | 25 MG
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Saxagliptin hydrochloride is a potent, selective, reversible, competitive, and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor with a Ki of 0.6-1.3 nM. This compound has potential for research into type 2 diabetes mellitus.
- Potent inhibitor of dipeptidyl peptidase-4 (DPP-4).
- Selective and reversible action.
- Orally active compound.
- Increases β-cell proliferation.
- Increases p-AKT and active β-catenin protein levels.
- Increases c-myc and cyclin D1 protein expression.
- Prevents degradation of glucagon-like peptide-1.
- Increases secretion of insulin.
- Decreases secretion of glucagon.
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Medchemexpress LLC IACS-010759 | 1570496-34-2 | 99.7% | 562.56 | 100 MG
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IACS-010759 is an orally active, potent mitochondrial complex I inhibitor of oxidative phosphorylation (OXPHOS). It inhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS, making it suitable for research in relapsed/refractory AML and solid tumors.
- Potent mitochondrial complex I inhibitor
- Inhibits proliferation and induces apoptosis in cancer models
- Potential for solid tumor research
- Suitable for acute myeloid leukemia (AML) research
- Exhibits low plasma clearance and prolonged terminal half-life
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Medchemexpress LLC Dioxopromethazine hydrochloride | 15374-15-9 | MFCD01706903 | 100.0% | 352.88 g·mol⁻¹ | C17H21ClN2O2S | 5 MG
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Dioxopromethazine hydrochloride is an orally active antihistamine used in research to study histamine-related responses and the inhibition of asthmatic symptoms. Supplied as the hydrochloride salt, it is intended for preclinical and in vitro assay applications.
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Medchemexpress LLC Tracazolate hydrochloride | 1135210-68-2 | MFCD03791317 | 99.2% | 340.85 g/mol | C16H25ClN4O2 | 10 MG
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Tracazolate hydrochloride is the hydrochloride salt of tracazolate (ICI 136753), a potent positive allosteric modulator of GABAA receptors with reported subtype selectivity. It is supplied as a research reagent for in vitro and in vivo studies of GABAA receptor pharmacology, anxiolytic effects, and anticonvulsant activity.
- Potent GABAA receptor positive allosteric modulator.
- Reported selectivity for the β3 subunit.
- High purity (99.2%).
- Off-white to light yellow solid appearance.
- Recommended storage: -20°C, sealed, protect from moisture.
- Available in small research pack sizes such as 10 MG.
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Medchemexpress LLC Trihexyphenidyl hydrochloride | 52-49-3 | MFCD00058212 | 99.9% | 100 MG
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Trihexyphenidyl hydrochloride | 52-49-3 | MFCD00058212 | 99.9% | 100 MG
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Medchemexpress LLC PF-07038124 hydrochloride | 2415317-57-4 | 99.3% | C18H23BClNO4 | 1 MG
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PF-07038124 hydrochloride is a potent PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2. It demonstrates immunomodulatory effects by inhibiting IL-13, IL4, and IFNγ, making it suitable for research related to atopic dermatitis and plaque psoriasis. This compound has been investigated in Phase 1 and Phase 2 clinical trials for these conditions. It is supplied as an off-white to light yellow solid.
- Specifically targets PDE4B2 with high potency
- Shows inhibitory activity against IL-13, IL4, and IFNγ
- Used in the study of atopic dermatitis and plaque psoriasis
- Investigated in Phase 1 and Phase 2 clinical trials
- Soluble in DMSO at 100 mg/mL
- Recommended storage is 4°C sealed, away from moisture
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