Carboxylic acid esters

Organic compounds that are directly derived from carboxylic acid, and contain an ester functional group substitution; ester groups contain an oxygen atom that is bonded to two carbon atoms or organic groups via single bonds.

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1,051 – 1,065 of 1,430 results

1,051

Medchemexpress LLC Tegaserod (maleate) | 189188-57-6 | 99.9% | C20H27N5O5 | 1 G

Tegaserod maleate is an orally active compound that functions as a serotonin receptor 4 agonist and a serotonin receptor 2B antagonist. It demonstrates inhibitory activity against 5-HT2A, 5-HT2B, and 5-HT2C receptors. This compound has been observed to induce apoptosis in tumor cells, inhibit PI3K/Akt/mTOR signaling, and reduce S6 phosphorylation. It shows promise for anti-tumor applications and research into irritable bowel syndrome.

Orally active serotonin receptor 4 agonist.
Serotonin receptor 2B antagonist.
Induces tumor cell apoptosis.
Inhibits PI3K/Akt/mTOR signaling and decreases S6 phosphorylation.
Exhibits anti-tumor activity, delays tumor growth, reduces metastases, and increases survival.
Potential for irritable bowel syndrome research.

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1,052

Medchemexpress LLC NB-598 (maleate) | 155294-62-5 | MFCD22665748 | 99.4% | 565.74 | C31H35NO5S2 | 10 MG

NB-598 maleate is a research-grade small molecule that acts as a potent, competitive inhibitor of squalene epoxidase (SE). It is used in biochemical and cell-based studies to suppress triglyceride and sterol biosynthesis via the farnesol pathway and is supplied as the maleate salt in solid form or as a concentrated DMSO solution for assay use.

Potent competitive inhibitor of squalene epoxidase.
Used to suppress triglyceride and cholesterol biosynthesis in biochemical studies.
Supplied as the maleate salt for improved stability and handling.
Available as small solid quantities and as a 10 mM solution in DMSO for convenience in assays.
High reported purity (~99.4%) suitable for research applications.

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1,053

Sigma Aldrich Fine Chemicals Biosciences Phenramne Maleate Pharma300mg

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

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1,054

eMolecules 922-67-8 | Methyl propiolate | Ambeed | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 10g | 552720843

Methyl propiolate | Ambeed | 922-67-8 | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 10g | 552720843

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1,055

TARGETMOL CHEMICALS INC FG-2216 25MG

Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. FG-2216 (YM-311) is a potent HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme (IC50 3.9 uM); orally bioavailable and induced reversible and significant Epo induction in vivo. purity: 99%

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1,056

Medchemexpress LLC Pd-168077 maleate | 630117-19-0 | 99.6% | 450.49 | 1 ML

PD-168077 maleate is a selective dopamine D4 receptor agonist with a Ki of 9 nM. It is intended for research use only. It exhibits intrinsic activity at the D4 receptor, leading to quinpirole-like inhibition of forskolin-stimulated cAMP accumulation or stimulation of [3H]thymidine uptake.

Shows >100-fold selectivity over other D2-like receptor family members and D1-like counterparts.
Demonstrates 20-fold selectivity over α1 and α2 receptors.
Exhibits 45-fold selectivity over 5-HT1A.
Shows 460-fold selectivity over 5-HT2A receptors.
Induces synaptic translocation of Ca2+/calmodulin-dependent protein kinase II in cultured prefrontal cortical neurons.

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1,057

Medchemexpress LLC Perhexiline (maleate) | 6724-53-4 | 100 MG

Perhexiline maleate is an orally active CPT1 and CPT2 inhibitor that reduces fatty acid metabolism. It induces mitochondrial dysfunction and apoptosis in hepatic cells. It can cross the blood brain barrier (BBB) and shows anti-tumor activity. It can be used in the research of cancers, and cardiovascular diseases like angina.

Reduces fatty acid metabolism
Induces mitochondrial dysfunction and apoptosis in hepatic cells
Can cross the blood-brain barrier
Exhibits anti-tumor activity
Suitable for research in cancers and cardiovascular diseases like angina

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1,058

Apexbio Technology LLC Trimipramine (maleate) 521-78-8 1g

Trimipramine (maleate) is a tricyclic antidepressant that exerts antagonistic activities at histamine H1 serotonin 5-HT2A and 1-adrenergic receptors with reported Kd values of 0 27 nM 24 nM and 24 nM respectively It also moderately interacts with muscarinic cholinergic receptors (Kd 58 nM) and dopamine D2 receptors (Kd 180 nM) Additionally trimipramine exhibits modest inhibitory effects on serotonin reuptake (Ki 149 nM for SERT) with weaker inhibition of norepinephrine (Ki 2 5 M for NET) and dopamine transporters (Ki 3 8 M for DAT) It is frequently utilized in neuropharmacological research to explore receptor-mediated neuronal signaling pathways and therapeutic mechanisms underlying depression

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1,059

Medchemexpress LLC Asenapine maleate | 85650-56-2 | 99.95% | 401.84 | 10 MM 1 ML

Asenapine maleate (Org 5222 maleate) is a brain-penetrant atypical antipsychotic. It acts as an antagonist for serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4), and histamine receptors (pKi: 8.2-9.0). This compound is utilized in research for conditions such as schizophrenia and bipolar disorder.

Antagonist of serotonin, adrenoceptors, dopamine, and histamine receptors.
Brain-penetrant atypical antipsychotic.
Used in schizophrenia and bipolar disorder research.
Higher affinity for 5-HT2C, 5-HT2A, 5-HT2B, 5-HT7, 5-HT6, α2B and D3 receptors relative to D2.
May offer superior therapeutic effects on anxiety.
Demonstrates anxiolytic-like effects in animal models.

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1,060

Apexbio Technology LLC NB-598 Maleate 155294-62-5 5mg

NB-598 Maleate is a small-molecule inhibitor targeting squalene epoxidase (SE) an essential enzyme in cholesterol biosynthesis It is designed to inhibit SE thereby disrupting the oxygenation of squalene and affecting downstream synthesis of cholesterol intermediates particularly within farnesol-dependent pathways leading to triglyceride biosynthesis NB-598 Maleate exerts its biological activity primarily through inhibition of squalene epoxidase In mouse pancreatic islet models NB-598 Maleate reduces insulin secretion under both basal and glucose-stimulated conditions Additionally this compound inhibits calcium voltage-dependent (CaV) ion channels in cellular assays Based on these pharmacological properties NB-598 Maleate holds research potential in studying cholesterol biosynthesis pathways lipid metabolism insulin regulation and the physiological role of CaV channels

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1,061

Medchemexpress LLC Way-100635 maleate | 1092679-51-0 | MFCD01321056 | 99.6% | 538.64 g/mol | C29H38N4O6 | 10 MG

WAY-100635 maleate is the maleate salt of WAY-100635, a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist supplied for research use in in vitro and in vivo pharmacology studies.

Potent 5-HT1A receptor antagonist (IC50 0.91 nM; Ki 0.39 nM)
High purity (≈99.6%) suitable for analytical and pharmacological studies
Molecular weight 538.64 g/mol; formula C29H38N4O6
Available in small pack sizes for research, including 10 mg
For research use only; not for human or veterinary use

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1,062

Medchemexpress LLC Cipralisant maleate | 223420-20-0 | 99.8% | 332.39 g·mol-1 | C18H24N2O4 | 10 MG

Cipralisant maleate is a research-grade histamine H3 receptor antagonist supplied as the maleate salt. It is used in pharmacology and neuroscience studies to probe H3 receptor activity and related signaling pathways. Provided as a solid with high reported purity, this compound is for laboratory research use only and not for human or veterinary applications.

Orally active histamine H3 receptor antagonist for research applications.
High purity (99.8%).
White to off-white solid appearance.
Soluble in DMSO (≥ 100 mg/mL).
Molecular weight 332.39 g·mol-1; formula C18H24N2O4.
Stable as powder at -20°C for long-term storage; in solution store at -80°C.
Supplied in small laboratory-scale quantities suitable for preclinical studies.

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1,063

Medchemexpress LLC Neratinib (maleate) | 915942-22-2 | 99.7% | 673.11 | 1 ML

Neratinib (HKI-272) maleate is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC50s of 59 nM and 92 nM, respectively. This product is for research use only.

Inhibits HER2 and EGFR with IC50s of 59 nM and 92 nM.
Shows anticancer activities against cancer cells expressing high levels of HER-2 or EGFR.
Reduces tumor growth in a dose-dependent manner in various xenografts.
Inhibits proliferation of cell lines with high HER-2 levels.
Arrests cell cycle at G1-S phase in BT474 cells.
Inhibits MAPK and Akt phosphorylation.
Down-regulates cyclin D1 levels and induces p27.
Inactive in MX-1 and MCF-7 xenografts.
Inhibited phosphorylation of HER-2 in BT474 xenografts.

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1,064

Medchemexpress LLC Cipralisant maleate | 223420-20-0 | 99.8% | 332.39 g/mol | C18H24N2O4 | 25 MG

Cipralisant maleate is a potent, selective histamine H3 receptor ligand used in neuroscience research. It functions as a full antagonist in vivo and shows agonist activity in vitro, with high receptor affinity; it is provided as a solid research chemical for pharmacological and behavioral studies involving wakefulness and attention mechanisms.

High affinity for histamine H3 receptor.
Potent antagonist activity in vivo.
Agonist activity observed in vitro.
High purity suitable for research applications.
Available in small-scale quantities with storage recommendations for stability.

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1,065

Medchemexpress LLC Pirepemat fumarate | 2251806-70-7 | 98.3% | 329.30 | C15H17F2NO5 | 5 MG

Pirepemat fumarate is a cortical-preferring catecholamine- and cognition-promoting research compound used in preclinical and translational studies of Parkinson's disease. Supplied as a solid powder with high reported purity, it is intended for laboratory research applications and is available in small pack sizes or as a standardized solution for screening.

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Carboxylic acid esters

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Medchemexpress LLC Tegaserod (maleate) | 189188-57-6 | 99.9% | C20H27N5O5 | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC NB-598 (maleate) | 155294-62-5 | MFCD22665748 | 99.4% | 565.74 | C31H35NO5S2 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pd-168077 maleate | 630117-19-0 | 99.6% | 450.49 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Perhexiline (maleate) | 6724-53-4 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Asenapine maleate | 85650-56-2 | 99.95% | 401.84 | 10 MM 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Way-100635 maleate | 1092679-51-0 | MFCD01321056 | 99.6% | 538.64 g/mol | C29H38N4O6 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Cipralisant maleate | 223420-20-0 | 99.8% | 332.39 g·mol-1 | C18H24N2O4 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Neratinib (maleate) | 915942-22-2 | 99.7% | 673.11 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Cipralisant maleate | 223420-20-0 | 99.8% | 332.39 g/mol | C18H24N2O4 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pirepemat fumarate | 2251806-70-7 | 98.3% | 329.30 | C15H17F2NO5 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More