Tricarboxylic acids and derivatives
Medchemexpress LLC diMal-O-CH2COOH | 1620837-47-9 | 96.8% | C13H12N2O7 | 5 MG
diMal-O-CH2COOH is a cleavable ADC linker, intended for research use only.
- Solid appearance, white to off-white color.
- Shipping at room temperature in continental US.
- Store at 4°C, protected from light and under nitrogen.
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light and under nitrogen.
- Relevant for cancer and cancer targeted therapy research.
Medchemexpress LLC 3,6,9,12-Tetraoxatridecanoic acid | 16024-60-5 | 96.0% | 250 MG
m-PEG3-CH2COOH is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs, which are designed to exploit the intracellular ubiquitin-proteasome system for selective protein degradation.
- PEG-based PROTAC linker
- Suitable for the synthesis of PROTACs
- High purity of 96.0%
- Stable in pure form at -20°C for 3 years or 4°C for 2 years
- Stable in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Amino-peg3-ch2cooh | 134978-99-7 | 99.9% | C8H17NO5 | 250 MG
Amino-PEG3-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs.
- Functions as a PEG-based PROTAC linker.
- Utilized in the synthesis of PROTACs.
- Has a chemical formula of C8H17NO5.
- Features a molecular weight of 207.22.
- Offers a purity of 99.9%.
- Requires storage at 4°C, protected from light.
- For solutions, store at -80°C for up to 6 months or -20°C for up to 1 month, protected from light.
Medchemexpress LLC Boc-NH-PEG1-CH2COOH | 142929-49-5 | 98.0% | C9H17NO5 | 1 G
Boc-NH-PEG1-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Molecular weight: 219.23
- Appearance: Solid-liquid mixture
- Color: Colorless to light yellow
- SMILES: O=C(O)COCCNC(OC(C)(C)C)=O
- Storage (pure form): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
- Solubility (in vitro): DMSO at 100 mg/mL (456.14 mM)
- Solubility (in vivo): Protocols available for DMSO, PEG300, Tween-80, Saline, SBE-β-CD, and Corn Oil
Medchemexpress LLC Enclomiphene citrate | 7599-79-3 | 99.9% | 598.09 | C32H36ClNO8 | 1 ML
Enclomiphene citrate is a research-grade, non-steroidal estrogen receptor antagonist supplied as a solid or as a ready-to-use 10 mM solution in DMSO for in vitro and in vivo studies.
- High purity typically 99.93%.
- Available as a 10 mM solution (1 mL) in DMSO or as mg-scale solids.
- Used for studies of ovarian dysfunction, testosterone deficiency, and male hypogonadism.
- Molecular weight 598.09, formula C32H36ClNO8, CAS 7599-79-3.
- Store powder at 4°C; stock solutions at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Adenosine 5'-(α,β-methylene)diphosphate triammonium | 99.9% | 476.32 | 50 MG
MethADP triammonium is a CD73 inhibitor that can be used for research of the ATP-adenosine pathway. It inhibits 5'-AMP induced adenosine formation in A498 cells at concentrations of 20 and 100 μmol/L. It is for research use only and not sold to patients.
- Inhibits 5'-AMP induced adenosine formation in A498 cells.
- For research use only.
- Off-white to light yellow solid.
- Store at 4°C, sealed, away from moisture and light.
- Store in solvent at -80°C for 6 months or -20°C for 1 month.
Medchemexpress LLC Boc-NH-PEG6-CH2COOH | 391684-36-9 | ≥98.0% | C19H37NO10 | 100 MG
Boc-NH-PEG6-CH2COOH is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. This compound is for research use only and not intended for patient use. It helps exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Molecular weight: 439.50
- Appearance: Colorless to light yellow liquid
- Density: 1.134±0.06 g/cm3
- Shipping at room temperature (continental US)
- Storage (pure form): -20°C for 3 years or 4°C for 2 years
- Storage (in solvent): -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Boc-NH-PEG2-CH2COOH | 108466-89-3 | 263.29 | 5 G
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is for research use only and not sold to patients.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- For research use only
- Molecular formula: C11H21NO6
- Appearance: Liquid, colorless to light yellow
- Storage: Pure form at -20°C for 3 years, 4°C for 2 years
- Storage: In solvent at -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO at 100 mg/mL
Medchemexpress LLC DiMal-O-CH2COOH | 1620837-47-9 | 96.8% | 308.24 | C13H12N2O7 | 10 MG
This cleavable linker is designed for use in antibody-drug conjugate (ADC) construction and conjugation workflows, offering malemide-based chemistry for attaching payloads to antibodies or targeting moieties. It is provided at research-grade purity and supplied in small quantities suitable for method development and exploratory studies.
- Cleavable linker for ADC construction and conjugation workflows.
- Provides maleimide-based chemistry for reliable payload attachment.
- High purity (96.8%) suitable for research applications.
- Available in small research quantities; larger amounts available on request.
- Store at 4°C, protect from light; in solvent: -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Adenosine 5'-(α,β-methylene)diphosphate triammonium | 00-00-0 | MFCD00042991 | 99.9% | 476.32 g·mol⁻¹ | C11H26N8O9P2 | 5 MG
MethADP triammonium (Adenosine 5'-(α,β-methylene)diphosphate triammonium) is a nucleotide analog used as a selective CD73 inhibitor for research into the ATP-adenosine pathway. Supplied as the triammonium salt, it is provided for laboratory research use in solid or solution form.
- CD73 inhibitor for ATP-adenosine pathway studies.
- High purity: 99.9%.
- Molecular weight 476.32 g·mol⁻¹; chemical formula C11H26N8O9P2.
- Appearance: off-white to light yellow solid.
- Storage: solid at 4°C; in solvent -80°C up to 6 months, -20°C up to 1 month.
- Available in small solid quantities and as a 10 mM solution.
Medchemexpress LLC Amino-PEG5-CH2COOH | 141282-35-1 | ≥97.0% | 500 MG
Amino-PEG5-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two distinct ligands connected by a linker; one targets an E3 ubiquitin ligase and the other targets the protein. They function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Targets PROTAC linkers within the PROTAC pathway
- Solid appearance
- White to off-white color
- Store at 4°C, protected from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
Medchemexpress LLC 2-methylcitric acid trisodium | 117041-96-0 | MFCD16875437 | 96.0% | 272.10 g·mol⁻1 | C7H7Na3O7 | 5 MG
2-Methylcitric acid trisodium is the trisodium salt of 2-methylcitric acid provided as a white to off-white solid for laboratory research. It is an endogenous metabolite used as a marker in methylmalonic and propionic acidemias and is employed in biochemical and mitochondrial studies, where it has been reported to inhibit ADP-stimulated mitochondrial respiration supported by glutamate.
- Trisodium salt, white to off-white solid.
- CAS number 117041-96-0.
- Purity 96.0%.
- Molecular weight 272.10 g·mol⁻1; formula C7H7Na3O7.
- Highly soluble in water (100 mg/mL; may require ultrasonication).
- Storage: sealed at 4°C; in solvent -80°C (6 months), -20°C (1 month).
- For research use only; not for human or veterinary use.
Medchemexpress LLC m-PEG8-CH2COOH | 102013-72-9 | 99.9% | 5 G
m-PEG8-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It has a molecular weight of 442.50 and a chemical formula of C19H38O11. This compound appears as a colorless to light yellow liquid with a density of 1.122 g/cm3. For in vitro solubility, it dissolves in DMSO at 200 mg/mL.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Molecular weight: 442.50
- Formula: C19H38O11
- Appearance: liquid
- Color: colorless to light yellow
- In vitro solubility: 200 mg/mL in DMSO
- Pure form storage: stable for 3 years at -20°C or 2 years at 4°C
- In solvent storage: stable for 6 months at -80°C or 1 month at -20°C
Medchemexpress LLC Fmoc-NH-PEG6-CH2COOH | 437655-96-4 | 99.4% | 561.62 | C29H39NO10 | 25 MG
Fmoc-NH-PEG6-CH2COOH is an Fmoc-protected PEG6 linker with a terminal carboxylic acid used as a hydrophilic spacer for conjugation chemistry. It is commonly used in antibody-drug conjugate (ADC) and PROTAC synthesis to provide a soluble linker and a protected amine for further derivatization.
- Cleavable PEG-based linker suitable for ADC and PROTAC synthesis.
- Provides an Fmoc-protected amine and a terminal carboxylic acid for conjugation.
- Molecular weight 561.62 and formula C29H39NO10.
- Purity 99.37% as reported by the supplier.
- Soluble in DMSO at 100 mg/mL; may require sonication.
- Storage: pure form -20 °C (3 years) or 4 °C (2 years); in solvent -80 °C (6 months) or -20 °C (1 month).
- Available in small lab pack sizes, including 25 mg.
Medchemexpress LLC 1-naphthol-3,6,8-trisulfonic acid trisodium salt | 31894-34-5 | MFCD03427540 | 97.0% | 450.31 g/mol | C10H5Na3O10S3 | 10MG
ζ-Stat trisodium (1-naphthol-3,6,8-trisulfonic acid trisodium salt) is the trisodium salt research reagent that functions as a selective atypical protein kinase C-ζ (PKC-ζ) inhibitor with reported in vitro antitumor activity (IC50 ≈ 5 μM). It reduces proliferation and induces apoptosis in certain melanoma cell lines and is supplied as a solid for biochemical and cell-based assays.
- Selective atypical PKC-ζ inhibitor (IC50 ≈ 5 μM).
- Demonstrated antiproliferative and pro-apoptotic activity in melanoma cell lines.
- Solid, light yellow appearance; purity 97.0%.
- Water soluble: 12.5 mg/mL in H2O with ultrasonic/warming (heat to 60°C).
- Store sealed, away from moisture; recommend 4°C; in solution keep at -80°C (6 months) or -20°C (1 month).
- Available in small research pack sizes including 10 mg.