HPLC Columns and Cartridges
Waters Corp Waters Symmetry Shield RP8 Intelligent Speed (IS) Column, 100 Å, 5 μm, 3.9 mm x 20 mm
These reversed-phase columns use patented embedded polar group technology, improving peak shape and resolution with exceptional repeatability.
- Embedded polar group technology shields silica’s residual silanol surface.
- Improves peak shape and resolution; offers exceptional repeatability.
- Performs well with highly aqueous mobile phases, preventing pore dewetting.
- Provides excellent peak shape across a broad pH range (2 to 8).
- Withstands a maximum pressure of 6000 psi (415 Bar).
Waters Corporation Symmetry Shield RP8 Prep Guard Cartridge, 5 μm, 100 Å
These reversed-phase columns feature embedded polar group technology, which “shields” the silica's residual silanol surface from highly basic analytes. This technology in the column significantly improves peak shape and resolution. This product is designed to be used with other parts.
- Extends analytical column lifetime by eliminating particle pollution.
- Prevents chemical contaminants and suspended materials from entering the analytical column.
- Manufactured in a cGMP, ISO 9001-certified laboratory with ultra-pure reagents.
- Each batch of packing material is chromatographically tested for consistent performance.
- Tested for optimal operation, boosting selectivity, sensitivity, and study speed.
- Constructed with high-performance packing materials to preserve column performance.
- Ideal for biological fluid cleanup and temperature control applications.
Waters Corp WATERS CORPORATION Oasis MCX Online Column, 80 Å, 30 μm, 3.9 mm X 20 mm
The Oasis MCX on-line column is engineered for robust, reproducible, and ultrafast on-line Solid Phase Extraction (SPE). It incorporates a unique mixed-mode polymeric sorbent designed for enhanced selectivity and sensitivity in extracting basic compounds with cation-exchange groups. This column features traditional HPLC column fittings and hardware.
- Filling material: MCX
- Separation mode: Mixed-mode
- Particle matrix: Copolymer
- pH range: 0 pH to 14 pH
- Endcapped: No
- Particle shape: Spherical
- Particle size: 30 μm
- Pore size: 80 Å
- Format: Online column
- Inner diameter: 3.9 mm
- Ion exchange capacity: 1 meq/gram
- Length: 20 mm
- Units per package: 1 pk
Waters Corp Symmetry C18 Prep Column, 300Å, 5 μm, 19 mm x 50 mm
This product primarily supports legacy methods. Symmetry columns are designed to ensure long-term compliance of HPLC methods, offering consistent peak shape, selectivity, column-to-column and batch-to-batch reproducibility, and other critical performance characteristics. They are available in various particle sizes, chemistries, and dimensions.
- Supports legacy methods.
- Offers confidence in long-term compliance of HPLC methods.
- Maintains peak shape, selectivity, and column-to-column and batch-to-batch reproducibility.
- Available in various particle sizes, chemistries, and dimensions.
- Chemistry: C18 (reversed phase).
- Particle substrate: Silica.
- pH range: 2 to 8.
- Temperature limits: 45°C.
- Maximum pressure: 6000 psi (415 Bar).
- Particle shape: Spherical.
- System: HPLC preparative.
- Technique: LC/MS, LC.
- USP classification: L1.
Waters Corp Waters BioSuite C18 Column, 500Å, 7 μm, 2 mm × 150 mm
The BioSuite C18 Column primarily supports legacy methods, featuring large pore size and high chemical stability. Its 500 Å pore size pC18 base matrix accommodates proteins up to 2,500,000 Daltons, providing greater protein or peptide binding capacity than nonporous chemistries.
- Chemistry: C18
- Separation mode: Reversed phase
- Particle substrate: Polymethacrylate
- PH range: 2 to 12 pH
- Maximum pressure: 6000 psi (415 Bar)
- Endcapped: Yes
- Molecular weight range: 1,000 to 30,000
- Particle shape: Spherical
- Particle size: 7 μm
- Endfitting type: Parker-style
- Pore size: 500 Å
- Format: Column
- System: HPLC
- USP classification: L1
- Inner diameter: 2 mm
- Length: 150 mm
- Application: Peptide
- Units per package: 1 per package
Waters Corp Waters Atlantis Silica HILIC Column, 100Å, 5 μm
HILIC Silica columns are designed for effective retention of analytes too polar for reverse-phase chromatography, utilizing high organic mobile phases (>80% acetonitrile). These columns are crucial for challenging separations of highly basic polar analytes in metabolism, drug discovery, and combinatorial chemistry.
- Provides orthogonal analyte selectivity compared to traditional reversed-phase approaches.
- Enhances sensitivity and lowers detection limits with ESI-MS.
- Offers improved LC/ESI-MS performance and direct compatibility with SPE solvents.
- Delivers superior peak morphologies for polar bases, facilitating quicker method development.
- Operates within a pH range of 1–5 pH and tolerates up to 6000 psi (415 Bar) maximum pressure.
- Features 5 μm spherical silica particles and 100 Å pore size.
- Dimensions: 2.1 mm inner diameter × 100 mm length.
Waters Corp Waters BioSuite C18 Column, 500Å, 13 μm, 21.5 mm × 150 mm
The BioSuite C18 Column supports legacy methods, offering a large pore size and high chemical stability. Its pC18 and pPhenyl resin-based packings are bonded to a pH stable, methacrylic ester-based polymeric resin. The 500 Å pore size accommodates proteins up to 2,500,000 Daltons. These columns provide superior chromatographic resolution, suitable for both “lab scale” isolations and narrow-bore HPLC/LC-MS applications.
- Chemistry: C18
- Separation mode: Reversed phase
- Particle substrate: Polymethacrylate
- pH range: 2 pH to 12 pH
- Maximum pressure: 6000 psi (415 Bar)
- Particle size: 13 μm
- Pore size: 500 Å
- Inner diameter: 21.5 mm
- Length: 150 mm
- Application: Peptide
Waters Corp XTerra Shield RP18 OBD Prep Column, 125Å, 10 µm, 30 mm X 250 mm, 1/pk
XTerra Preparative RP18 columns are hybrid-based, reversed-phase C18 columns that incorporate Waters patented embedded polar group technology to improve peak shape performance for highly basic compounds. These first generation columns provide superior pH stability compared to a silica-based column.
Waters Corp Waters μBondapak Prep Column, C18, 10 μm, 30 mm X 300 mm
μBondapak C18 columns are general-purpose, silica-based, reversed-phase C18 columns that are based on 10 μm particle technology. They offer a balance between resolution, throughput, and cost for preparative chromatography.
- General-purpose, silica-based, reversed-phase C18 columns
- Based on 10 μm particle technology
- Offers a balance between resolution, throughput, and cost for preparative chromatography
- Chemistry: C18
- Separation mode: Reversed phase
- Particle substrate: Silica
- pH range: 2 to 8 pH
- Temperature limits: 45 °C
- Maximum pressure: 6000 psi (415 Bar)
- Endcapped: Yes
- Silanol activity: High
- Particle shape: Irregular
- Pore size: 125 Å
- Inner diameter: 30 mm
- Length: 300 mm
- Carbon load: 10%
- Units per package: 1 pk
Waters Corp Symmetry Shield RP8 Column, 100Å, 5 µm, 4.6 mm X 100 mm, 1/pk
These reversed-phase columns contain Waters patented embedded polar group technology that “shields” the silica’ residual silanol surface from highly basic analytes. The reduced silanol activity for the SymmetryShield RP8 column significantly improves peak shape and resolution.
Waters Corp WATERS CORPORATION XTerra Prep MS C8 Column, 5 μm Particle Size, 50 mm x 100 mm, 125 Å Pore Size
- Hybrid particle (silica co-polymer) technology provides efficiency and stability.
- Wide pH range (1–12) for enhanced selectivity and improved peak shape.
- Rugged material offers high mechanical strength and high efficiency.
- Provides excellent peak shape for bases.
- Designed for mass spectrometry (MS) applications, delivering sharp peaks and good sensitivity.
- Trifunctional bonding chemistries ensure long lifetime and ultra-low bleed.
- Easy scale-up from analytical to preparative chromatography.
- Increased mass loading (up to 60x) at high pH.
- Carbon load: 12%.
- Proprietary end-capping.
- Operates within a temperature range of 20°C to 60°C.
- USP Class No. L7.
Waters Corp Waters OBD Prep Column, C8, 5 μm, 50 mm x 50 mm
XTerra Prep columns utilize patented Hybrid Particle Technology, specifically designed for preparative applications in discovery and development labs. They offer routine operation at pH 1 to 12, with up to 60 times more loading capacity. This increased capacity reduces injections for pure material and enables shorter columns for faster results.
- Hybrid Particle Technology for isolation and purification.
- Patented design specifically for preparative applications.
- Wide pH range (1 to 12) for broad operational flexibility.
- High loading capacity, up to 60 times more.
- Increased efficiency: fewer injections or more material per injection.
- Time savings in discovery through shorter columns for faster material production.
Waters Corp HPLC Column, C18 PA-B, 3.5 μm, 2.1 × 100 mm
This HPLC column is designed for reversed-phase chromatography of proteins and peptides. It features C18 PA-B chemistry, a 3.5 μm particle size, and 2.1 × 100 mm dimensions, suitable for analytical to preparative applications.
- Features C18 (pC18) chemistry on a pH stable polymeric resin, with 500 Å pore size for proteins up to 2,500,000 Daltons.
- Provides high chemical stability.
- Suitable for analytical, preparative, narrow-bore HPLC, and LC/MS applications.
- Separates proteins, peptides, and other biomolecules via reversed-phase chromatography at elevated pH.
- Supports characterization and isolation of biotherapeutics; addresses proteomics needs.
- Supports HPLC and LC/MS analyses of peptides and proteins.
Waters Corporation Prep Column, Silica, 6 μm, 30 mm x 300 mm
These silica-based, semi-preparative and preparative columns utilize 6 μm particle technology. They offer superior performance compared to 5 μm columns, providing higher resolution, more efficient separations, and faster chromatography.
- Silica-based
- 6 μm particle technology
- Higher resolution compared to 5 μm columns
- More efficient separations compared to 5 μm columns
- Faster chromatography compared to 5 μm columns
Waters Corp Waters Preparative Column, Shield RP18, 5 μm, 30 mm × 75 mm, 125 Å
XTerra Preparative RP18 columns are hybrid-based, reversed-phase C18 columns that incorporate Waters patented embedded polar group technology to improve peak shape performance for highly basic compounds. These first generation columns provide superior pH stability compared to a silica-based column.
- Hybrid-based, reversed-phase C18 columns.
- Incorporates embedded polar group technology to improve peak shape performance for highly basic compounds.
- Provides superior pH stability compared to a silica-based column.