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Filtered Search Results
AdipoGen Hydroxytyrosol
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Chemical. CAS 10597-60-1. Formula C8H10O3. MW 154.16. Synthetic. Phenolic component of olive oil. Metabolite of oleuropein. Antioxidant that inhibits both 12- and 5-lipoxygenase LO activity. The IC50 values for the inhibition of rat platelet 12-LO and rat neutrophil 5-LO are 4.2 and 13µM, respectively. It does not inhibit, and may actually enhance, COX activity. Protects LDL from both biological and chemical oxidation, suggesting a potential mechanism for the protective effects of olive oil against atherosclerosis. Inhibits the rate of cancer cell proliferation and induces cancer cell apoptosis. Also described to induce growth arrest and apoptosis in human colon carcinoma HT-29 cells through activation of the serine/threonine protein phosphatase 2A. Protects beta-Cells from amylin amyloid-Induced cytotoxicity.
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Cayman Chemical Entacaponed10 GC MS Standards
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An internal standard for the quantification of entacapone by GC- or LC-MS
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Cayman Chemical Docosahexaenoic Acid methyl e
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An esterified form of DHA; has been used as a reference standard in the quantification of fatty acids in microalgal and fish oils
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Medchemexpress LLC Tridecanedioic acid | 505-52-2 | 99.9% | 25 G
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Tridecanedioic acid, also known as Brassylic Acid, is an endogenous metabolite. It is associated with the metabolic regulation of non-alcoholic fatty liver disease (NASH) and may serve as a crucial node molecule within the interaction network between intestinal microbiota and host metabolism.
- Significantly accumulates in tolerant cabbage-type rapeseed varieties
- Plays an important role in defense against small cabbage moth infection
- Can be used as a biomarker for plant insect resistance
- Can be used as a diagnostic marker for metabolic diseases
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eMolecules 619-44-3 | 4-Iodobenzoic acid methyl ester | Chem-Impex | MFCD00016353 | 262.046 | C8H7IO2 | 99.000 | COC(=O)c1ccc(I)cc1 | 1kg | 322123381
4-Iodobenzoic acid methyl ester | Chem-Impex | 619-44-3 | MFCD00016353 | 262.046 | C8H7IO2 | 99.000 | COC(=O)c1ccc(I)cc1 | 1kg | 322123381
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Cayman Chemical 2-MethylhIppurIc AcId 5g
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A metabolite of xylene; has been found in the urine of industrial workers exposed to xylene
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Medchemexpress LLC 7-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)heptanoic acid | 2225940-50-9 | MFCD32063493 | 98.0% | C20H23N3O6 | 10MG
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Pomalidomide-C6-COOH is a pomalidomide-derived cereblon (CRBN) ligand featuring a six-carbon carboxylic acid linker designed for use as a building block in PROTAC and targeted protein degradation research. It is supplied as a solid with high analytical purity suitable for medicinal chemistry and chemical biology applications.
- Provides a carboxylic acid handle for linker attachment.
- Designed for PROTAC design and targeted protein degradation studies.
- High purity appropriate for research synthesis (≈98%).
- Soluble in DMSO for assay and synthetic workups.
- Supplied as a light yellow to yellow solid for ease of handling.
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Selleck Chemical LLC Novobiocin Sodium (NSC 2382) S2492-50mg
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Novobiocin Sodium (NSC 2382 Albamycin Cathomycin) is an aminocoumarin antibiotic that targets bacterial DNA gyrase (TopoIV) used to treat susceptible gram positive bacteria
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Medchemexpress LLC C.I. Acid black 94 | 6358-80-1 | 50 MG
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C.I. Acid black 94 | 6358-80-1 | 50 MG
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Medchemexpress LLC Mitochonic acid 5 (MA-5) | 1354707-41-7 | 99.6% | 329.30 | 1 MG
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Mitochonic acid 5 (MA-5) binds mitochondria, ameliorating renal tubular and cardiac myocyte damage. It modulates mitochondrial ATP synthesis independently of oxidative phosphorylation and the electron transport chain, protecting mitochondrial function by regulating energy metabolism and reducing oxidative stress. Oral administration has shown increased plasma concentration in a dose-response manner in mice, and it has improved renal function in ischemia-reperfusion injury and cisplatin-induced nephropathy models.
- Purity: 99.60%
- Appearance: Solid
- Color: Light yellow to yellow
- Molecular weight: 329.30
- Formula: C18H13F2NO3
- Solubility (in vitro): ≥ 100 mg/mL in DMSO; insoluble in H2O
- Storage conditions for powder: -20°C for 3 years, 4°C for 2 years
- Storage conditions in solvent: -80°C for 2 years, -20°C for 1 year
- Target: Mitochondrial metabolism
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Medchemexpress LLC Glyoxalic acid | 298-12-4 | 50% | C2H2O3 | 500 G
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Glyoxalic acid is an organic compound functioning as both an aldehyde and a carboxylic acid. It is supplied as a 50% w/w solution in water, appearing as a colorless to light yellow liquid. This compound is an endogenous metabolite and also identified as a human gut microbiota metabolite, intended for research use only.
- Functions as both an aldehyde and a carboxylic acid
- Induces fluorescence
- Utilized in the study of neurons
- Classified under ketones, aldehydes, and acids
- Human endogenous metabolite
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Medchemexpress LLC Gossypol (acetic acid) | 12542-36-8 | 99.8% | 578.61 | 5 G
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Gossypol acetic acid ((±)-Gossypol-acetic acid) binds to Bcl-xL protein and Bcl-2 protein, making it suitable for cancer research and studies involving the Bcl-2 family.
- Targets Bcl-2 Family
- Used in cancer research
- Binds to Bcl-xL protein with a Ki of 0.5-0.6 μM
- Binds to Bcl-2 protein with a Ki of 0.2-0.3 mM
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TARGETMOL CHEMICALS INC KPT9274 5MG
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Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. KPT9274 (PAK4-IN-1) is a non-competitive dual inhibitor of PAK4 and NAMPT(IC50= ~120 nM). It is an orally bioavailable small molecule. purity: 99%
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Medchemexpress LLC Gambogic acid | 2752-65-0 | 98.8% | 628.75 g/mol | C38H44O8 | 10 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Gambogic acid is a natural xanthonoid compound isolated from the resin of Garcinia hanburyi that functions as a Bcl-2 family inhibitor and is supplied for research use.
- CAS number: 2752-65-0.
- Molecular formula: C38H44O8.
- Molecular weight: 628.75 g/mol.
- Purity: 98.8% (typical).
- Appearance: yellow to orange solid.
- Storage: powder at -20°C (long term) or 4°C (short term); in solution at -80°C (long term).
- Available in solid and solution formats, including 10 MG solid and solution concentrations for research applications.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Myristelaidic acid | 50286-30-1 | MFCD00133547 | 99.8% | 226.36 | C14H26O2 | 10MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Myristelaidic acid (trans-9-tetradecenoic acid) is a 14-carbon trans monounsaturated fatty acid supplied for research use. It is the trans isomer of myristoleic acid and occurs in many animal fats. The product is provided as a purified analytical reagent; consult the certificate of analysis and safety data sheet for purity, handling, and storage recommendations.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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