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Filtered Search Results
Medchemexpress LLC HS-276 | 2767422-72-8 | 98.9% | 419.52 | 100 MG
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HS-276 is an orally active, potent, and highly selective TAK1 inhibitor with a Ki of 2.5 nM. It significantly inhibits multiple kinases, including TAK1, CLK2, GCK, ULK2, and MAP4K5. This compound is useful for rheumatoid arthritis (RA) research due to its ability to reduce inflammation and improve arthritis markers in models.
- Orally active and highly selective TAK1 inhibitor
- Inhibits various kinases, such as TAK1, CLK2, and GCK
- Reduces expression of TNF, IL-6, and IL-1β
- Decreases inflammation and cartilage damage in inflammatory arthritis models
- Exhibits excellent bioavailability in in vivo studies
- Suitable for rheumatoid arthritis research
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Sigma Aldrich Fine Chemicals Biosciences Ristomycin monosulfate 90100MG
Ristomycin/ristocetin is a type III glycopeptide. It is a highly glycosylated glycopeptide previously found innbspAmycolatopsis lurida.
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Sigma Aldrich Fine Chemicals Biosciences Valinomycin 99.0 TLC500MG
Valinomycinnbspis a neutral cyclic dodecadepsipeptide antibiotic that has a 36-member ring.
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Medchemexpress LLC HY-12451 1mg Medchemexpress, FICZ CAS:172922-91-7 Purity:>98%
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Medchemexpress, HY-12451 1mg FICZ CAS:172922-91-7 FICZ is a potent aryl hydrocarbon receptor (AhR) agonist with a Kd of 70 pM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-13441 10mg Medchemexpress, (-)-Blebbistatin CAS:856925-71-8 Purity:>98%
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Medchemexpress, HY-13441 10mg (-)-Blebbistatin CAS:856925-71-8 (-)-Blebbistatin is a selective inhibitor of the ATPase activity of non-muscle myosin II[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-42110 10mg Medchemexpress, Deschloroclozapine CAS:1977-07-7 Purity:>98%
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Medchemexpress, HY-42110 10mg Deschloroclozapine CAS:1977-07-7 Deschloroclozapine is a potent, high affinity, selective, metabolically stable agonist of muscarinic-based DREADDs. Deschloroclozapine inhibites [3H]quinuclidinyl benzilate (QNB) binding to hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM. Deschloroclozapine is reported with utility in both mice and non-human primates for a variety of applications. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-15230 10mg Medchemexpress, Geldanamycin CAS:30562-34-6 Purity:>98%
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Medchemexpress, HY-15230 10mg Geldanamycin CAS:30562-34-6 Geldanamycin is a Hsp90 inhibitor with antimicrobial activity against many Gram-positive and some Gram-negative bacteria. Geldanamycin has anti-influenza virus H5N1 activities. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Enzo Life Sciences Concanamycin A (25µg). CAS: 80890-47-7
Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1 (BML-CM110). Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Exhibits cytotoxic effects in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production. Inhibits Autophagy. Alternative name: Folimycin. Purity: ≥98% (HPLC). Appearance: White to off-white solid (sub-milligram quantities will appear as clear film). Solubility: Soluble in methanol, DMSO or acetonitrile; insoluble in water. Long Term Storage: -20°C.
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Medchemexpress LLC HY-11102 10mg Medchemexpress, RO4929097 CAS:847925-91-1 Purity:>98%
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Medchemexpress, HY-11102 10mg RO4929097 CAS:847925-91-1 RO4929097 (RG-4733) is a γ secretase inhibitor with IC50 of 4 nM, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-10518 10mg Medchemexpress, BMS-345541 (hydrochloride) CAS:547757-23-3 Purity:>98%
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Medchemexpress, HY-10518 10mg BMS-345541 (hydrochloride) CAS:547757-23-3 BMS-345541 hydrochloride is a selective inhibitor of the catalytic subunits of IKK (IKK-2 IC50=0.3 μM, IKK-1 IC50=4 μM). BMS-345541 binds at an allosteric site of IKK. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-19930 10mg Medchemexpress, Vaborbactam CAS:1360457-46-0 Purity:>98%
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Medchemexpress, HY-19930 10mg Vaborbactam CAS:1360457-46-0 Vaborbactam (RPX7009) is a cyclic boronic acid pharmacophore β-lactamase inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-19791 1mg Medchemexpress, N-Acetyl-Calicheamicin CAS:108212-76-6 Purity:>98%
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Medchemexpress, HY-19791 1mg N-Acetyl-Calicheamicin CAS:108212-76-6 0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-12646 5mg Medchemexpress, Rhosin (hydrochloride) CAS:1281870-42-5 Purity:>98%
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Medchemexpress, HY-12646 5mg Rhosin (hydrochloride) CAS:1281870-42-5 Rhosin hydrochloride is a potent, specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of ~ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride induces cell apoptosis[2]. Rhosin hydrochloride promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability[3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-15667 10mg Medchemexpress, P005091 CAS:882257-11-6 Purity:>98%
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Medchemexpress, HY-15667 10mg P005091 CAS:882257-11-6 P005091 is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with an EC50 of 4.2 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-16578 5mg Medchemexpress, GW9662 CAS:22978-25-2 Purity:>98%
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Medchemexpress, HY-16578 5mg GW9662 CAS:22978-25-2 GW9662 is a potent and selective PPARγ antagonist with an IC50 of 3.3 nM, showing 10 and 1000-fold selectivity over PPARα and PPARδ, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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