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Filtered Search Results
Selleck Chemical LLC Sulfacetamide sodium salt hydrate S4750-100mg
Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase(DHPS) with IC50 of 9 5 M Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA) which is required for bacterial synthesis of folic acid
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Medchemexpress LLC Oss 128167 | 887686-02-4 | 98.6% | 366.32 | C19H14N2O6 | 25 MG
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OSS_128167 is a research-use small molecule that selectively inhibits sirtuin 6 (SIRT6). It has been characterized in cellular and animal studies and shows activity on histone acetylation, metabolic regulation, antiviral effects against hepatitis B virus, and chemosensitization in cancer models. Supplied as a high-purity solid.
- Selective SIRT6 inhibition (IC50 = 89 μM).
- Lower activity against SIRT1 and SIRT2 (IC50s = 1578 μM and 751 μM).
- Demonstrated anti-HBV activity in vitro and in vivo.
- Increases H3K9 acetylation and GLUT-1 expression in cells.
- Induces chemosensitization in multiple myeloma cell lines.
- High reported purity and supplied as a white to light yellow solid.
- For research use only; not for human or clinical use.
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Medchemexpress LLC Xanomeline | 131986-45-3 | MFCD00867179 | 100.0% | 281.42 g/mol | C14H23N3OS | 5 MG
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Xanomeline is a selective muscarinic M1/M4 receptor agonist (CAS 131986-45-3) supplied as a solid analytical standard for laboratory research. It is provided in small pack sizes for analytical and preclinical studies; reported molecular formula C14H23N3OS and molecular weight 281.42 g/mol. Not for clinical use.
- High purity suitable for analytical work.
- Selective M1/M4 receptor agonist for neuroscience research.
- Solid form enables easy weighing and storage.
- Available in small package sizes for method development and pilot studies.
- Accompanied by safety documentation for proper handling.
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Medchemexpress LLC JH-II-127 | 1700693-08-8 | 98.0% | 416.86 | 50 MG
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JH-II-127 is an orally active, highly potent, selective, and brain-permeable LRRK2 inhibitor, with IC50s of 6 nM for wild-type LRRK2, 2 nM for LRRK2-G2019S, and 48 nM for mutant LRRK2-A2016T. It inhibits Ser935 phosphorylation in all tissues of mice, including the brain. JH-II-127 can be used in the study of Parkinson's syndrome.
- Orally active, highly potent, selective, and brain-permeable LRRK2 inhibitor
- Inhibits Ser935 phosphorylation in all tissues of mice, including the brain
- Can be used in the study of Parkinson's syndrome
- Demonstrated good oral bioavailability in vivo
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Apexbio Technology LLC Tylosin phosphate 1405-53-4 50mg
Tylosin phosphate (CAS 1405-53-4) is a small-molecule inhibitor targeting bacterial ribosomal subunits It is designed to interfere with bacterial translation thereby inhibiting bacterial protein synthesis Tylosin phosphate exerts its biological activity primarily through binding to ribosomal subunits of Gram-positive bacteria In in vitro studies tylosin phosphate demonstrates inhibitory activity with reported IC50 values generally ranging between 0 5 5 g/mL depending on bacterial strain and assay conditions Based on these pharmacological properties tylosin phosphate holds research potential in studies of antibiotic resistance mechanisms antibacterial spectrum evaluation and as an antibiotic additive to explore growth promotion and therapeutic utility in poultry swine and bovine models
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Medchemexpress LLC Clindamycin-¹³C,d₃ | 2140264-63-5 | 99.9% | 1 MG
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Clindamycin-13C,d3 is a 13C- and deuterium labeled version of Clindamycin, a broad-spectrum, orally active bacteriostatic lincosamide antibiotic. It inhibits bacterial protein synthesis and can suppress the expression of virulence factors in *Staphylococcus aureus* at sub-inhibitory concentrations. Resistance to Clindamycin occurs due to enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). It reduces the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1), or alpha-haemolysin (Hla). Additionally, Clindamycin can be used in malaria research.
- Can be used as a tracer.
- Can serve as an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS.
- Stable heavy isotopes (hydrogen, carbon, and other elements) are incorporated into drug molecules, primarily as tracers for quantitation during drug development.
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Medchemexpress LLC Erythromycin estolate | 3521-62-8 | 10 MM * 1 ML
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Erythromycin estolate is a macrolide antibiotic and a derivative of Erythromycin used to treat a wide variety of bacterial infections. It is intended for research use only and not sold to patients. This compound can cause liver injury, primarily cholestatic hepatitis, due to its inhibitory effect on bile acid transport.
- Purity: 98.0%
- Molecular weight: 1056.39
- Formula: C52H97NO18S
- Functions as a macrolide antibiotic
- Used to treat bacterial infections
- Inhibits various flaviviruses including Zika, dengue, and yellow fever
- Inactivates viral particles by destroying viral membrane integrity
- Inhibits human BSEP with an IC50 of 4.1 μM
- Available as a solid, white to off-white in color
- Storage conditions: 4°C in sealed storage, away from moisture; in solvent: -80°C for 6 months or -20°C for 1 month
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Medchemexpress LLC Rifampicin (Standard) | 13292-46-1 | 95.5% | 25 MG
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Rifampicin (Standard) is a potent and broad-spectrum antibiotic effective against bacterial pathogens. It also exhibits anti-influenza virus and anti-orthopoxvirus activities. This analytical standard is intended for research and analytical applications.
- Used as a reference standard for assays
- Employed in qualitative, quantitative, and methodological research experiments
- Effective against bacterial pathogens
- Exhibits anti-influenza virus activity
- Shows anti-orthopoxvirus activity
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Medchemexpress LLC HY-15427 5mg Medchemexpress, GDC-0834 CAS:1133432-49-1 Purity:>98%
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Medchemexpress, HY-15427 5mg GDC-0834 CAS:1133432-49-1 GDC-0834 is a potent and selective BTK inhibitor. GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC50 of 1.1 and 5.6 μM in mouse and rat, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-15781A 5mg Medchemexpress, Morinidazole (R enantiomer) CAS:898230-59-6 Purity:>98%
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Medchemexpress, HY-15781A 5mg Morinidazole (R enantiomer) CAS:898230-59-6 Morinidazole R enantiomer is the R-enantiomer of Morinidazole. Morinidazole is a new 5-nitroimidazole class antimicrobial agent. Morinidazole R enantiomer is the less active enantiomer. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 2009-98-5 | ethyl 2-diazo-3-oxopentanoate | Synthonix170.168 | C7H10N2O3 | 99.000 | CCOC(=O)C(=[N+]=[N-])C(=O)CC | 50mg | 779537001
ethyl 2-diazo-3-oxopentanoate | Synthonix | 2009-98-5170.168 | C7H10N2O3 | 99.000 | CCOC(=O)C(=[N+]=[N-])C(=O)CC | 50mg | 779537001
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Medchemexpress LLC Huperzine B | 103548-82-9 | MFCD01716207 | 98.7% | 256.34 g/mol | C16H20N2O | 10 MG
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Huperzine B is a Lycopodium alkaloid and a selective acetylcholinesterase (AChE) inhibitor used as a research reagent. It is supplied as a purified white to off-white solid with high purity and is suitable for biochemical and pharmacological studies.
- Selective acetylcholinesterase inhibitor.
- High purity (98.7%).
- White to off-white solid form.
- Available in milligram quantities and in DMSO solution for assays.
- Suitable for biochemical and pharmacological research applications.
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eMolecules 30233-64-8 | Medchem Express | Monobehenin | 100mg | 437899502 | HY-20349 | 432.686 | C25H52O5
AstaTech | ETHYL 2-BROMO-2-(PYRIDIN-2-YL)ACETATE | 0.25g | 781205048 | 93370 | 95.000 | 74376-32-2 | MFCD27928220 | 244.088 | C9H10BrNO2
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Medchemexpress LLC HY-101097 5mg Medchemexpress, PD-1-IN-17 CAS:1673560-66-1 Purity:>98%
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Medchemexpress, HY-101097 5mg PD-1-IN-17 CAS:1673560-66-1 PD-1-IN-17 is a programmed cell death-1 ( PD-1 ) inhibitor extracted from patent WO2015033301A1, Compound 12, inhibits 92% splenocyte proliferation at 100 nM [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC ICA-105665 (PF-04895162) | 2694728-63-5 | 99.9% | 355.34 | C19H15F2N3O2 | 10MG
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ICA-105665 is a research small molecule that acts as a neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channel opener. It is provided as a powder for in vitro and in vivo studies, and is intended for research use only. Store the solid at low temperature for long-term stability and follow standard handling practices for research chemicals.
- Potent neuronal Kv7 channel opener for electrophysiology and pharmacology studies.
- Suitable for in vitro and in vivo research applications.
- High research-grade purity reported at about 99.9%.
- Molecular weight 355.34 g/mol; chemical formula C19H15F2N3O2.
- Stable when stored at recommended low temperatures.
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