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Filtered Search Results
Medchemexpress LLC HY-101298 5mg Medchemexpress, Paprotrain CAS:57046-73-8 Purity:>98%
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Medchemexpress, HY-101298 5mg Paprotrain CAS:57046-73-8 Paprotrain is a cell-permeable inhibitor of the kinesin MKLP-2 , inhibits the ATPase activity of MKLP-2 with an IC 50 of 1.35 μM and a K i of 3.36 μM and shows a moderate inhibition activity on DYRK1A with an IC 50 of 5.5 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-N0281 10mg Medchemexpress, Daphnetin CAS:486-35-1 Purity:>98%
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Medchemexpress, HY-N0281 10mg Daphnetin CAS:486-35-1 Daphnetin (7,8-dihydroxycoumarin), one coumarin derivative isolated from plants of the Genus Daphne, is a protein kinase inhibitor, with IC 50 s of 7.67 μM, 9.33 μM and 25.01 μM for EGFR, PKA and PKC in vitro, respectively [1] [2] . Daphnetin (7,8-dihydroxycoumarin) is a secondary metabolite of plants used in folk medicine to counter inflammatory and allergic diseases, also has been clinically used in the treatment of coagulation disorders, rheumatoid arthritis with anti-malarian and anti-pyretic properties [3] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-N6718 1mg Medchemexpress, Filipin III CAS:480-49-9 Purity:>98%
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Medchemexpress, HY-N6718 1mg Filipin III CAS:480-49-9 Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Chloramphenicol (Standard) | 56-75-7 | 99.7% | 50 MG
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Chloramphenicol (Standard) | 56-75-7 | 99.7% | 50 MG
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AdipoGen Gentamicin sulfate USP Grade
Chemical. CAS 1405-41-0. Formula C21H43N5O7 . H2SO4 unspecified. MW 575.6. Isolated from Micromonospora sp. Aminoglycoside antibiotic. Protein synthesis inhibitor. Causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site. Antibacterial against Gram-negative aerobic bacteria, Gram-positive bacteria and mycoplasmas. Used as a selection agent gentamicin-resistance gene in molecular biology applications. Broad-spectrum cell culture antibiotic that is nontoxic to viruses and mammalian cells at antibacterial and antimycoplasmal concentrations. Due to its extended stability and slow development of bacterial resistance, it is a useful antibiotic in long-term virus und tissue culture studies. Bactericidal effects are exerted by the binding to the outer membrane, causing disruption of the membrane.
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Medchemexpress LLC Oxolamine citrate | 1949-20-8 | MFCD00083457 | 99.9% | 500 MG
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Oxolamine citrate is an orally active antitussive that can inhibit CYP2B1/2. It exhibits anti-inflammatory effects on the respiratory organs. This product increases the AUC of Warfarin and prolongs its terminal half-life. It is intended for use in respiratory disease research.
- Inhibits CYP2B1/2
- Exhibits anti-inflammatory effects on respiratory organs
- Increases the AUC of Warfarin
- Prolongs Warfarin's terminal half-life
- Reduces plasma protein binding of Clarithromycin in fresh rat plasma
- Protects pulmonary parenchyma from emphysema in animal models
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Medchemexpress LLC Spectinomycin dihydrochloride pentahydrate | 22189-32-8 | 98.0% | 1 ML
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Spectinomycin dihydrochloride pentahydrate is a broad-spectrum antibiotic that inhibits the growth of various gram-positive and gram-negative organisms. It functions by selectively targeting bacterial ribosomes and disrupting protein synthesis. Additionally, it acts as a noncompetitive inhibitor of td intron RNA with a Ki value of 7.2 mM.
- Broad-spectrum antibiotic
- Specific mechanism of action: selectively targets bacterial ribosomes to interrupt protein synthesis
- Inhibits td intron RNA
- Available in multiple forms
- Research use only
- High purity: guaranteed at 98.0% purity
- Solubility: soluble in water at 62.5 mg/mL (126.17 mM)
- Storage flexibility: can be stored at 4°C (sealed, away from moisture) for solid form; stock solutions can be stored at -80°C for 6 months or -20°C for 1 month
- Detailed documentation
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Medchemexpress LLC Anisomycin | 22862-76-6 | 99.5% | 265.31 | 50 MG
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Anisomycin (Standard) is a potent protein synthesis inhibitor that interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system. It also acts as a JNK activator, increasing phospho-JNK levels, and functions as a bacterial antibiotic. This analytical standard is intended for research and analytical applications, and is commonly used in qualitative, quantitative, and methodological research experiments involving techniques such as HPLC, GC, and MS.
- Potent protein synthesis inhibitor
- Interferes with protein and DNA synthesis
- Inhibits peptidyl transferase or the 80S ribosome system
- JNK activator
- Increases phospho-JNK levels
- Bacterial antibiotic
- Analytical standard for research and analytical applications
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
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Medchemexpress LLC Epothilone B | 152044-54-7 | 99.9% | 507.68 | 100 MG
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Epothilone B | 152044-54-7 | 99.9% | 507.68 | 100 MG
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Medchemexpress LLC ANISOMYCIN STANDARD | 5MG
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ANISOMYCIN STANDARD | 5MG
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Medchemexpress LLC Loratadine-d5 | 1398065-63-8 | 99.96% | 387.91 | 5 MG
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Loratadine-d5 is the deuterium labeled Loratadine. Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. It has anti-dengue-virus (DENV) activity and can inhibit immunologic release of inflammatory mediators. It can be used as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Selective inverse peripheral histamine H1-receptor agonist.
- Has anti-dengue-virus (DENV) activity.
- Can inhibit immunologic release of inflammatory mediators.
- Can be used as a tracer or an internal standard for quantitative analysis.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
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Medchemexpress LLC Azithromycin | 83905-01-5 | 98.0% | 748.98 | 1 ML
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Azithromycin hydrate is a macrolide antibiotic useful for the treatment of a number of bacterial infections. It is intended for research use only.
- Enhances rhinovirus-induced IFNβ expression in primary bronchial epithelial cells from asthmatics.
- Represses viral replication.
- Reduces MMP-9 mRNA and protein levels without affecting NF-κB in endotoxin-challenged monocytic THP-1 cells.
- Augments expression of interferon-stimulated genes and the pattern recognition receptor MDA5.
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Medchemexpress LLC Miglustat hydrochloride | 210110-90-0 | 98.0% | 255.74 | 50 MG
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Miglustat (N-Butyldeoxynojirimycin) hydrochloride is an orally active and reversible ceramide glucosyltransferase inhibitor, with blood-brain barrier permeability. It can be used for the research of type I gaucher disease.
- Orally active and reversible ceramide glucosyltransferase inhibitor
- Blood-brain barrier permeability
- Used for research of type I Gaucher disease
- Restores F508del-CFTR function in cystic fibrosis (CF) bronchial epithelial IB3-1 and CuFi-1 cells
- Reduces inflammatory response to P. aeruginosa in both CF and non-CF bronchial cells
- Able to rescue synaptic plasticity deficits, to restore ERKs activation and to counteract hyperexcitability in NPC1-/- mice
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Medchemexpress LLC Azithromycin-13C,d3 | 2750534-82-6 | 99.9% | 753.00 | 500 UG
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Azithromycin-13C,d3 is the deuterium and 13C labeled Azithromycin. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Medchemexpress LLC Acyclovir-d4 (Aciclovir-d4) | 1185179-33-2 | 98.7% | 229.23 | 5 MG
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Acyclovir-d4 is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. It inhibits HSV-1 (IC50 of 0.85 μM), HSV-2 (IC50 of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination. Acyclovir also prevents bacterial infections during induction therapy for acute leukaemia.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
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