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Filtered Search Results
Medchemexpress LLC IRAK4-IN-4 50mg | 1850276-58-2 | 50 MG
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IRAK4-IN-4 is a research small-molecule inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) with additional activity against cyclic GMP-AMP synthase (cGAS). Supplied as a light yellow solid with reported high purity, it is used in biochemical and cellular studies to probe IRAK4- and cGAS-mediated signaling pathways in inflammation and autoimmune disease research.
- Potent IRAK4 inhibition (IC50 2.8 nM).
- Potent cGAS inhibition (IC50 2.1 nM).
- High purity (99.6%).
- Light yellow solid physical form.
- Molecular weight 340.37 g/mol.
- Suitable for preclinical biochemical and cellular assays.
- Available in multiple small milligram pack sizes for research use.
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Apexbio Technology LLC Betamipron 3440-28-6 50mg
Betamipron (CAS 3440-28-6) is a small-molecule inhibitor targeting renal tubular uptake mechanisms It is designed to inhibit renal tubular uptake thereby reducing nephrotoxicity during carbapenem antibiotic therapy Betamipron exerts its biological activity primarily through blockade of the renal tubular uptake process Its potency is typically assessed via renal uptake assays and cellular transporter inhibition tests however exact IC50 values depend on experimental conditions and models and are not explicitly provided Based on these pharmacological properties Betamipron holds research potential in the investigation of antibiotic-related renal pharmacokinetics carbapenem distribution profiles and nephrotoxic side-effects
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Medchemexpress LLC Sirolimus | 53123-88-9 | MFCD00867594 | 99.0% | 914.17 g/mol | C51H79NO13 | 50 MG
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Analytical standard of rapamycin (sirolimus) supplied as a solid reference material for research and analytical use. It provides defined identity and high purity for assay calibration, method development, and quality control.
- Analytical standard of sirolimus (rapamycin).
- High purity (98.98%) suitable for analytical applications.
- Molecular formula C51H79NO13; molecular weight 914.17 g/mol.
- Provided as a solid powder for laboratory use.
- Available in a 50 MG pack size for analytical workflows.
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eMolecules 177355-84-9 | N2,N4-Dibenzylquinazoline-2,4-diamine | MFCD03691820 | 50mg
Ambeed | Methyl 3-bromothiophene-2-carboxylate | 5g | 552678498 | A255746 | 26137-08-6 | MFCD00173839 | 221.070 | C6H5BrO2S
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
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Medchemexpress LLC 4-(2′-aminoethyl)amino-1,8-dimethylimidazo[1,2-a]quinoxaline | 445430-58-0 | MFCD18089812 | 99.7% | 255.32 g·mol⁻1 | C14H17N5 | 25 MG
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BMS-345541 is a small-molecule research reagent that selectively inhibits the catalytic subunits of IκB kinase (IKK). It binds an allosteric site on IKK and is used to probe NF-κB signaling pathways in biochemical and cellular studies. The compound is supplied with analytical characterization for research use only.
- Selective inhibition of IKK catalytic subunits, with greater potency for IKK-2
- Binds an allosteric site on the IKK enzyme
- Reported IC50 values: IKK-2 = 0.3 μM; IKK-1 = 4 μM
- High analytical purity suitable for research applications
- Available in multiple pack sizes, including 25 MG
- Molecular formula C14H17N5 and molecular weight 255.32 g·mol⁻1
- Offered as solid and as ready-to-use DMSO solution formats
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Medchemexpress LLC Anhydrotetracycline hydrochloride | 13803-65-1 | ≥98.0% | 462.88 | C22H23ClN2O7 | 10 MG
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Anhydrotetracycline hydrochloride is a tetracycline-family antibiotic supplied as an analytical reference standard for laboratory research. It is commonly used as an effector in tetracycline-regulated gene expression systems and for analytical method development. The material is provided as the hydrochloride salt with molecular weight 462.88 g·mol⁻1 and chemical formula C22H23ClN2O7.
- Reference standard for research and analytical applications.
- Acts as an effector in tetracycline-regulated gene expression systems.
- Supplied as a hydrochloride salt; formula C22H23ClN2O7 and MW 462.88 g·mol⁻1.
- High reported purity (≥98%) suitable for analytical work.
- Available in small laboratory pack sizes (e.g., 10 MG, 50 MG).
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Medchemexpress LLC HY-B0274 50mg Medchemexpress, Chlorprothixene CAS:113-59-7 Purity:>98%
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Medchemexpress, HY-B0274 50mg Chlorprothixene CAS:113-59-7 Chlorprothixene is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. Antipsychotic activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-109619 5mg Medchemexpress, D4-abiraterone CAS:154229-21-7 Purity:>98%
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Medchemexpress, HY-109619 5mg D4-abiraterone CAS:154229-21-7 D4-abiraterone is a major metabolite of abiraterone. D4-abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid-5a-reductase (SRD5A) and also an antagonist of androgen receptor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-111746 10mg Medchemexpress, CWHM-1008 CAS: Purity:>98%
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Medchemexpress, HY-111746 10mg CWHM-1008 CAS: CWHM-1008 is a potent and orally active antimalarial agent, with EC50 values of 46 and 21 nM against drug-sensitive Plasmodium falciparum 3D7 and drug-resistant Dd2 strains, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Enzo Life Sciences Nigericin. sodium salt (5mg). CAS: 28643-80-3; 28380-24-7
Acts as an H+, K+, Na+, Pb2+ ionophore. Is most commonly an antiporter of H+ and K+. Stimulates Ca2+ release from mitochondrial stores by disruption of membrane potantial. Inhibits the Golgi functions. Activator of NALP3. Alternative name: Antibiotic K 178. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (10mg/ml, heating may be required), dichloromethane (10mg/ml), methanol (10mg/ml), ethanol (5mg/ml) and ethyl acetate. Long Term Storage: -20°C.
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Research Products International Corp TOBRAMYCIN SULFATE, 1GM
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Tobramycin Sulfate is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, leading to the misreading of mRNA and preventing the proper initiation complex formation. This interference disrupts the translation process and inhibits bacterial growth.
Tobramycin is used in microbiology for selective bacterial isolation and in antibiotic sensitivity testing to determine the susceptibility of bacterial strains. Ideal for studying bacterial susceptibility patterns and antibiotic resistance. Its inclusion in culture media can help selectively isolate bacteria that are susceptible to this antibiotic.
WARNING! This product can expose you to Tobramycin sulfate, a chemical which is known to the State of California to cause developmental harm. For more information go to www.P65Warnings.ca.gov.
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Medchemexpress LLC HY-110390 5mg Medchemexpress, GR148672X CAS:263890-70-6 Purity:>98%
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Medchemexpress, HY-110390 5mg GR148672X CAS:263890-70-6 GR148672X is a triacyglycerol hydrolase (TGH) inhibitor with an IC50 of 4 nM extracted from patent WO 2001016358 A2. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Research Products International Corp Streptomycin Sulfate, 100 Grams
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Streptomycin Sulfate is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, disrupting the initiation complex and leading to misreading of mRNA. This interference prevents proper translation and inhibits bacterial growth.
Streptomycin is employed in microbiology for selective bacterial isolation and antibiotic sensitivity testing to assess the susceptibility of bacterial strains. Ideal for studying bacterial susceptibility patterns and antibiotic resistance. Its inclusion in culture media aids in selectively isolating bacteria susceptible to this antibiotic.
WARNING! This product can expose you to Streptomycin sulfate, a chemical which is known to the State of California to cause developmental harm. For more information go to www.P65Warnings.ca.gov.
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CPC Scientific H-Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser-OH (trifluoroacetate salt) 0.5MG
A hemolytic and antimicrobial peptide isolated from frog skin. This naturally occurring peptide causes a change in membrane permeability and forms cation-selective channels at concentrations over 2 µM.ONE-LETTER SEQUENCE: GIGKFLHSAKKFGKAFVGEIMNSMOLECULAR FORMULA: C114H180N30O29S1MOLECULAR WEIGHT:2466.93STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [108433-95-0], SYNONYMS: Magainin IIRESEARCH AREA: AntimicrobialREFERENCES: A. Mor et al., Biochemistry, 30, 8824 (1991)
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Medchemexpress LLC Tebipenem pivoxil | 161715-24-8 | 99.7% | 5 MG
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Tebipenem pivoxil is an orally active antibiotic that works against various pathogenic bacteria by binding to penicillin-binding protein (PBP), thereby inhibiting cell wall synthesis. It is intended for research use only.
- Orally active antibiotic
- Binds penicillin-binding protein (PBP), thereby inhibiting cell wall synthesis
- Excellent antibacterial activity against various pathogenic bacteria
- Shows inhibition with MIC50s below 64 μg/mL against tested Gram-positive and Gram-negative bacteria
- Significantly protects sepsis mice challenged with various pathogenic bacteria
- Significantly increased the survival number of sepsis mice within a 168 h observation period
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