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Filtered Search Results
American Radiolabeled Chemicals Inc TTP 1,2-3H 1LC
Thymidine 5'-methyl-1',2'-3H triphosphate ammonium salt (TTP) 1mCi in ethanol:water (1:1), 1 mCi/ml, 80-120 Ci/mmol, M.W. 501.21, Shipped in Dry Ice, Exclusive
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Medchemexpress LLC Sacubitrilat | 149709-44-4 | 99.1% | 383.44 | 100 MG
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Sacubitrilat (Desethyl Sacubitril) is an active neprilysin (NEP) inhibitor, designed for research use only. It is a single diastereomer that binds to the active site of NEP with high inhibitory potency.
- Active neprilysin (NEP) inhibitor
- Single diastereomer with specific stereocenters
- High inhibitory potency (5 nM)
- For research use only
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Medchemexpress LLC Sirolimus (rapamycin) | 53123-88-9 | MFCD00867594 | 914.17 g/mol | C51H79NO13 | 50 MG
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Rapamycin (sirolimus) is a macrolide mTOR inhibitor supplied in a GMP-like grade for research and cell-therapy process applications. It is provided as a white to off-white solid intended for research use only and not for human therapeutic use.
- Acts as an mTOR inhibitor supporting autophagy and signaling pathway research.
- GMP-like grade suitable as an auxiliary reagent in cell therapy manufacture.
- Solid, white to off-white appearance for straightforward handling and storage.
- Molecular formula C51H79NO13 and molecular weight 914.17 g/mol for accurate formulation.
- CAS number 53123-88-9 enables unambiguous chemical identification.
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Medchemexpress LLC Ampicillin (trihydrate) | 7177-48-2 | 99.9% | 10 G
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Ampicillin trihydrate is a broad-spectrum beta-lactam antibiotic. It is effective against a variety of gram-positive and gram-negative bacteria and is intended for research use only. It appears as a white to off-white solid.
- Broad-spectrum beta-lactam antibiotic
- Effective against gram-positive and gram-negative bacteria
- Inhibits growth of E. coli of swine origin
- Provides neuroprotection against ischemia-reperfusion brain injury
- Reduces activities of MMPs and increases GLT-1 expression
- Reduces medial hippocampal cell death following global forebrain ischemia
- Identified uses include laboratory chemicals and manufacture of substances
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Medchemexpress LLC (R)-6-chloro-N-(4-fluoro-2-(methylsulfonyl)phenyl)-7-hydroxy-4-oxo-4H-chromene-2-carboxamide | 2438637-65-9 | 99.8% | 435.81 g/mol | C19H11ClFNO6S | 5 MG
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PGAM1-IN-1 is a small-molecule inhibitor of phosphoglycerate mutase 1 (PGAM1) with an enzymatic IC50 of 6.4 μM and demonstrated cellular activity (H1299 proliferation IC50 14.1 ± 1.9 μM). Supplied as a high-purity research reagent, the compound has molecular formula C19H11ClFNO6S and molecular weight 435.81 g/mol. For research use only.
- Inhibits phosphoglycerate mutase 1 with an IC50 of 6.4 μM.
- Shows H1299 cell proliferation inhibition (IC50 14.1 ± 1.9 μM).
- High purity (>99.8%).
- Available as solid and as a 10 mM solution in DMSO.
- Molecular formula C19H11ClFNO6S; molecular weight 435.81 g/mol.
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Research Products International Corp Kanamycin Monosulfate [Kanamycin A], 25 Grams
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Kanamycin A is a broad-spectrum aminoglycoside antibiotic derived from Streptomyces kanamyceticus. It is widely used in microbiology, molecular biology, and genetic engineering as a selective agent. Commonly added to culture media, Kanamycin A inhibits the growth of non-resistant bacteria, allowing selection of cells carrying a kanamycin resistance gene. It is frequently used in recombinant DNA experiments and as a selectable marker in plasmids and other vectors. Researchers also use it to study bacterial resistance and antimicrobial efficacy. Its potency and low toxicity make it valuable in protein expression and genetic studies.
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Alkali Scientific Amphotericin B, 100 Mg
Amphotericin B is a polyene antifungal agent widely used in microbiology and cell culture applications to prevent and control fungal contamination. It functions by binding to ergosterol in fungal cell membranes, creating pores that disrupt membrane integrity and lead to cell death. This mechanism makes it highly effective against a broad range of yeasts and molds. In laboratory settings, Amphotericin B is commonly added to culture media to maintain sterile conditions during experiments. It is also used in research involving fungal pathogens, antifungal susceptibility testing, and studies focused on membrane biology and antifungal drug development.
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Medchemexpress LLC (E)-N-(3-methyl-1,1-dioxo-1,4-thiazinan-4-yl)-1-(5-nitrofuran-2-yl)methanimine | 23256-30-6 | MFCD00869254 | 99.7% | 287.29 g/mol | C10H13N3O5S | 100 MG
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Nifurtimox is a nitrofuran antiprotozoal compound provided as a research-grade chemical for laboratory studies. It is commonly used in experimental models of Trypanosoma cruzi infection and in preclinical studies such as neuroblastoma research and enzyme activity assays.
- Antiprotozoal nitrofuran compound for research applications.
- Used in Trypanosoma cruzi infection models and neuroblastoma studies.
- Reported to modulate lactate dehydrogenase (LDH) activity in assays.
- Reported purity 99.72%.
- Molecular formula C10H13N3O5S and molar mass ~287.29 g/mol.
- Available as a 100 mg research pack.
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eMolecules 502487-67-4 | Medchem Express | SQ109 | 5mg | 446264859 | HY-14989 | 330.56 | C22H38N2
Medchem Express | SQ109 | 5mg | 446264859 | HY-14989 | 502487-67-4 | 330.560 | C22H38N2
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Medchemexpress LLC N1-Acetylspermidine hydrochloride | 34450-16-3 | 99.1% | 260.20 | 10 MG
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N1-Acetylspermidine hydrochloride is an acetyl derivative of polyamines and acts as a substrate for polyamine oxidase (PAO). It is utilized in colorectal cancer research and can promote apoptosis when combined with Procyanidins.
- Acetyl derivative of polyamines
- Acts as a substrate for polyamine oxidase (PAO)
- Promotes apoptosis when combined with Procyanidins
- Exhibits cleavage efficiency at apurinic sites of DNA
- Useful in colorectal cancer research
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Medchemexpress LLC 17-allylamino-17-demethoxygeldanamycin | 75747-14-7 | MFCD04973892 | 99.0% | 585.69 g/mol | C31H43N3O8 | 200 MG
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Tanespimycin (17-AAG) is a benzoquinone-derived HSP90 inhibitor used as a research tool in cellular and biochemical studies of HSP90-dependent signaling and oncology models. It displays low-nanomolar potency against HSP90 and is provided in multiple pack formats for laboratory use.
- Potent HSP90 inhibitor with an IC50 of 5 nM.
- Preferential binding to tumor-derived HSP90 compared with normal HSP90.
- Purity 99.01% as supplied.
- Molecular formula C31H43N3O8; molecular weight 585.69 g/mol.
- CAS number 75747-14-7.
- Available as solid and solution formats, including a 200 mg pack.
- Store protected from light; in solvent: -80°C (up to 6 months) or -20°C (up to 1 month).
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Medchemexpress LLC HY-107419 5mg Medchemexpress, NU6140 CAS:444723-13-1 Purity:>98%
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Medchemexpress, HY-107419 5mg NU6140 CAS:444723-13-1 NU6140 is a selective CDK2-cyclin A inhibitor ( IC 50 , 0.41 μM), exhibits 10- to 36-fold selectivity over other CDKs [1] . NU6140 also potently inhibits Aurora A and Aurora B , with IC 50 s of 67 and 35 nM, respectively [2] . Enhances the apoptotic effect, with anti-cancer activity [1] [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-107765 5mg Medchemexpress, LY2955303 CAS:1433497-19-8 Purity:>98%
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Medchemexpress, HY-107765 5mg LY2955303 CAS:1433497-19-8 LY2955303 is a potent and selective retinoic acid receptor gamma (RARγ) antagonist with a Ki of 1.09 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Vancomycin hydrochloride from Streptomyces orientalis meets USP testing specifications | 1404-93-9 | 1G
Vancomycin hydrochloride from Streptomyces orientalis meets USP testing specifications | Mol Wt: 1485.71 | 1404-93-9 | 1G
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Medchemexpress LLC HZX-02-059 | 2240205-30-3 | 99.4% | 487.48 | 50 MG
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HZX-02-059 is a potent methuosis inducer and dual-target PIKfyve/tubulin inhibitor with anticancer activity. Methuosis primarily disrupts the balance of endocytosis and exocytosis, leading to the formation of numerous vesicles and inducing cell death. This compound also induces cell vacuolization, promotes apoptosis, downregulates the p53 pathway, inhibits PI3K/AKT phosphorylation, and inhibits c-Myc and NF-κB transcription.
- Potent methuosis inducer
- Dual-target PIKfyve/tubulin inhibitor
- Anticancer activity
- Induces cell vacuolization
- Promotes apoptosis
- Downregulates the p53 pathway
- Inhibits PI3K/AKT phosphorylation
- Inhibits c-Myc and NF-κB transcription
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