Goat Secondary Antibodies
Cayman Chemical 4MethylethcathInon metabolI
A metabolite of 4-MEC that features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,S and S,R orientations at carbons one and two, as in ephedrine; intended for research and forensic applications
Cayman Chemical 1-O-Hexadecyl-sn-glycerol, Purity: ≥95%, CAS: 506-03-6, 250 mg
An alkyl glyceryl ether; reduces UVB-induced cell death and production of ROS and PGE2 in NHEKs; increases coronary flow and left ventricular developed pressure and reduces MDA formation ex vivo in a rat heart model of ischemia/reperfusion injury
Cayman Chemical 5hydroxy SaxaglIptInhydroc
A major active metabolite of saxagliptin; inhibits DPP-4 (Ki = 2.6 nM for human recombinant enzyme); selective for DPP-4 over DPP-8 and DPP-9 (Kis = 2,495 and 423 nM, respectively, for human recombinant enzymes)
Cayman Chemical Methylene Blue (hydrate), Purity: ≥95%, CAS: 122965-43-9, 100 g
A cationic dye with diverse biological activities; inhibits the catalytic function of inducible and constitutive nitric oxide synthases; inhibits MAO and increases the activity of mitochondrial cytochrome C oxidase; stabilizes systemic circulation without increasing peripheral resistance, decreases lipid peroxidation, and reduces anoxic tissue injury in brain and heart in a porcine model of global ischemia and reperfusion injury; inhibits MAO activity in brain and reduces the age-related decline in grip strength and spatial memory in old mice at 250 μM in drinking water; reduces immobility time in the forced swim test in mice at 15,30, and 60 mg/kg; commonly used to stain cells and tissues in research
Cayman Chemical Ritodrine (hydrochloride), Purity: ≥98%, CAS: 23239-51-2, 1 g
A β2-AR agonist; induces relaxation of isolated pig detrusor muscle from 0.001-1 μM; reduces electrically-induced isometric tension in myometrial strips isolated from rabbits on day 25 of pregnancy at 30 μg/ml; suppresses spontaneous motility of and increases concentration of cAMP in isolated pregnant rat uterus
Cayman Chemical 1,2-Dilinoleoyl-sn-glycerol, Purity: ≥95%, CAS: 24529-89-3, 50 mg
A DAG; has been found as a component of phosphatidic acid in rat liver mitochondria and in spinach chloroplast membranes; upregulated in some pregnant women and has been used as a biomarker to predict later preeclampsia in early pregnancy
Cayman Chemical Diphencyprone, Purity: ≥95%, CAS: 886-38-4, 500 mg
A contact sensitizing agent; pretreatment reduces symptom severity in a mouse model of MBP1-10-induced EAE; enhances IL-10 production and antigen-specific IgG2a antibody responses and reduces anaphylaxis and asthma induced by ovalbumin in mice at 1% v/v; topical administration increases intrafollicular CD4+ and CD8+ T cells, reduces upper dermal inflammation, and stimulates hair growth in the C3H/HeJ mouse model of alopecia areta
Cayman Chemical Hecogenin Acetate, Purity: ≥98%, CAS: 915-35-5, 10 g
A steroid sapogenin; reduces the percentage of mobile larvae in goat fecal cultures containing Haemonchus, Oesophagostomum, and Trichostrongylus nematodes (EC50 = 0.49 mg/ml); inhibits development of mechanical hyperalgesia induced by carrageenan, TNF-α, dopamine, and PGE2 at 5, 10, or 20 mg/kg; increases latency to tail withdrawal in the tail flick test in mice at 40 mg/kg
Cayman Chemical Dipeptide diaminobutyroyl benzylamide (hydrochloride), Purity: ≥98%, 100 mg
A biomimetic peptide and muscarinic acetylcholine receptor antagonist; blocks sodium uptake and induces muscle relaxation
Cayman Chemical 1,2,3-Trielaidoyl Glycerol, Purity: ≥95%, CAS: 537-39-3, 100 mg
A triacylglycerol; dietary administration reduces serum cholesterol levels in rats compared to corn oil-fed control animals; has been used as a substrate to determine the substrate specificity of S. rimosus extracellular lipase
Cayman Chemical Dracorhodin Perchlorate, Purity: ≥98%, CAS: 125536-25-6, 250 mg
A pro-apoptotic compound and a synthetic analog of dracorhodin; cytotoxic to U937, A375-S2, and MCF-7 cells in a concentration-dependent manner; cytotoxic to HeLa cells, an effect that can be reversed by Ac-YVAD-CMK, A-DEVD-FMK, Z-IETD-FMK, and Z-LEHD-FMK, which are inhibitors of caspase-1, -3, -8, and -9, respectively
Cayman Chemical 1,2-Dierucoyl-sn-glycero-3-PC, Purity: ≥98%, CAS: 51779-95-4, 250 mg
A phospholipid; has been used in the study of lipid membranes and to determine the effect of long-chain phospholipids on the secondary structure of hIAPP
Cayman Chemical 2'-Deoxycytidine (hydrochloride), Purity: ≥98%, CAS: 3992-42-5, 5 g
A deoxyribonucleoside; phosphorylated by deoxycytidine kinase in the cytosol or TK2 in mitochondria to form dCMP; oral administration in combination with deoxythymidine delays disease onset and increases lifespan in a mouse model of TK2 deficiency
Cayman Chemical 2-Methoxyhydroquinone, Purity: ≥90%, CAS: 824-46-4, 25 g
A phenolic compound; reduces TNF-α-induced CCL2 production in vitro (IC50 = 64.3 µM); has been used as a precursor in the synthesis of geldanamycin
Cayman Chemical p-Nitrophenyl β-D-Galactopyranoside, Purity: ≥98%, CAS: 3150-24-1, 10 g
A β-D-galactosidase chromogenic substrate; cleavage by β-D-galactosidase releases p-nitrophenol, which can be quantified by colorimetric detection at 420 nm as a measure of β-D-galactosidase activity