Custom Peptides
Cayman Chemical 1 2DInonadecnoylracglycer 10mg
A fluorescent probe for carbon monoxide undergoes the Pd0-mediated Tsuji-Trost reaction to release 27-dichlorofluorescein in the presence of Pd and carbon monoxide can be used to detect carbon monoxide production in vitro and in live cells ex/em 493/527 nm respectively
Cayman Chemical 1Stearoyl2Docosahexaenoyl 10mg
An inhibitor of AChE and BChE (IC50s 0.35 and 1 M respectively for the human enzymes) reduces organophosphate pesticide-induced decreases in AChE activity at 10 UM reduces soman-induced membrane depolarization and decreases in AChE activity in isolated human muscle bundles in a concentration-dependent manner prevents tachycardia and increases in sympathetic tone in mice following myocardial infarction induced by left coronary artery ligation at 3 mg/kg per day for four weeks
Cayman Chemical 11-HexadecenoIc AcId 10mg
An internal standard for the quantification of C16 ceramide by GC- or LC-MS
Cayman Chemical ntIpaInhydrochlorIde 10mg
A ribonucleoside with broad-spectrum antiviral activity reduces the number of viral plaques in BHK-21 cells infected with dengue type 2 reovirus type 1 West Nile and yellow fever RNA viruses (EC50s 95 26 80 and 75 M respectively) inhibits HCV replication (EC50 2.2 M in a replicon assay) protects MDBK cells from BVDV and HCoV infection (EC50s 2.2 and 90 M respectively) reduces infectious virus yield in BHK-21 cells infected with FMDV and SVDV (EC50s 6.4 and 45.2 M respectively) reduces viral shedding to undetectable levels in a mouse model of persistent norovirus infection
Cayman Chemical PramlIntIdeacetAT hydrAT 10mg
A PKD1 inhibitor (IC50 7 UM) also inhibits CAK and PLK1 but has no activity at AKT (IC50s 8.4 21.9 and 50 UM respectively) inhibits PKD1 activity in LNCaP cells (IC50 0.21 UM) a byproduct in the synthesis of CID-755673
Cayman Chemical 1PalmItoyl3Stearoylracgl 10mg
An alkaloid with diverse biological activities inhibits growth of M. luteus and S. aureus in an inhibitory disc assay (30 g/disc) inhibits growth of the Bacille Calmette-Guerin M. bovis strain (MIC 12.5 g/ml) inhibits attachment of B. neritina larvae to PVC plates without inducing lethality (EC50 6.35 g/ml LC50 200 g/ml in paint used to coat PVC plates)
Cayman Chemical DItyrosInhydrochlorIde 10mg
Immunogen Synthetic peptide from the C-terminus of human STING protein Host Mouse Species Reactivity ( ) Human Applications ELISA IHC and WB MW 42 kDa
Cayman Chemical 1MyrIstoyl2Oleoyl3Docosa 10mg
An internal standard for the quantification of ( )-ropivacaine by GC- or LC-MS
Cayman Chemical 1 2 3TrIlgnocRoyl GlycRol 10mg
A fluorescent neuronal retrograde tracer labels the nucleus nucleolus cell body proximal dendrites and axons of neurons ex/em 373/404 nm respectively
Cayman Chemical NItIdInchlorIde 10mg
An iridoid glycoside has anti-apoptotic pro-angiogenic and radioprotective properties protects against mitochondrial pathway-dependent apoptosis in PC12 rat adrenal pheochromocytoma cells and H9c2 rat embryonic ventricular myocardial cells at a concentration of 10 UM pretreatment at concentrations of 25-100 Ug/ml reduces apoptosis and improves viability in AHH-1 human lymphocyte cells exposed to ionizing radiation reduces radiation-induced intestinal damage in mice pretreated at doses of 25-100 mg/kg i p improves angiogenesis in a rat model of stroke by increasing erythropoietin and VEGF expression in the brain at a dose of 5 mg/kg i p
Cayman Chemical Heptnoyl-L-carnItInchlorI 10mg
A synthetic GNRH agonist binds to GNRHR (Ki 0.2 nM in CHO cells expressing the human receptor) stimulates oxytocin and vasopressin release ex vivo from the isolated rat hypothalamo-neurohypophysial system (100 nM) initial dose of 100 g stimulates acute increases in LH FSH and testosterone serum levels (50- 2.5- and 15-fold respectively) while chronic treatment leads to 95 decreases in LH and FSH responses in rhesus monkeys
Cayman Chemical Black Tea TheaflavIn 10mg
An a2-AR agonist (Kis 93 1380 and 3890 nM for a2A- a2B- and a2C-ARs respectively) EC50s 52 288 and 602 nM for a2A- a2B- and a2C-ARs respectively for stimulated [35S]GTPYS binding Ki 19 nM for imidazoline receptor 1 lowers blood pressure in hypertensive rats in a dose-dependent manner when administered at a dose of 0.3-5 mg/kg improves spatial working memory deficits induced by hypobaric hypoxia in rats
Cayman Chemical ArnbIa sInsIs AlknIn 10mg
An inhibitor of c-fos/AP-1 inhibits the DNA binding activity of c-fos/AP-1 without affecting the activity of C/EBPa ATF2 MyoD Sp1 and NF-KB/p65 in vitro inhibits the development of collagen-induced arthritis in mice through reduction of IL-1B production neutrophil infiltration and synovial cell proliferation reduces the inflammatory cytokine response in LPS-challenged mice lowering levels of TNF-a and HMGB1 in the serum and MIP-1a and MCP-1 in the liver reduces in vivo necrosis of liver tissue and improves survival rates in LPS-challenged mice reduces proliferation and migration of HSC-3-M3 head and neck squamous carcinoma cells in vitro and the number of metastases in an HSC-3-M3 orthotopic xenograft model in vivo
Cayman Chemical GInkgolIde C 10mg
An ester derivative of fluprostenol a potential prodrug to 9-keto fluprostenol a potential metabolite of fluprostenol isopropyl ester (travoprost)