Custom Peptides
Cayman Chemical PalustrIc AcId 10mg
A diterpenoid with diverse biological activities; increases secreted hydrogen peroxide levels in isolated mouse macrophages at 2 mg/ml; toxic to water fleas and rainbow trout (LC50s = 0.1 and 0.5 mg/L, respectively); phloem levels are increased in mechanically injured, as well as mechanically injured and L. abietinum-infected, red pine and white spruce trees; has been found as an environmental contaminant in pulp and paper mill effluent
Cayman Chemical RezIvertInIb 10mg
An inhibitor of mutant EGFR; selectively inhibits the proliferation of mutant-EGFR-containing PC-9, HCC827, and H1975 cells (GI50s = 13.3, 6.8, and 22 nM, respectively) over wild-type EGFR-containing A431 cells (GI50 = >1,000 nM); increases survival in an H1975 brain orthotopic rat model
Cayman Chemical MethoxphenIdInhydrochLRId 10mg
An analog of diphenidine featuring a methoxy group at the two position of a phenyl group
Cayman Chemical C22 CeramIded18 122 0 10mg
A bioactive sphingolipid; forms small channels in liposomes, suggesting that acyl chain length is important in mitochondrial-mediated apoptosis; decreases the mitochondrial-to-cytosolic stress response in C. elegans following hsp-6 RNAi
Cayman Chemical PCMPAhydrochlorIde 10mg
A synthetic drug which is structurally related to the psychoactive compound phencyclidine; recently been identified as a likely drug of abuse
Cayman Chemical BMK ethyl glycIdate 10mg
An analytical reference standard categorized as a precursor in the synthesis of phenylacetone; intended for research and forensic applications
Cayman Chemical AlmorexnthydrochlorIde 10mg
An orexin 1 and orexin 2 receptor antagonist (Kis = 4.7 and 0.9 nM, respectively); decreases the latency to persistent NREM and REM sleep and increases the duration of NREM and REM sleep in male rats when administered at a dose of 100 mg/kg; does not impair spatial learning and memory in the Morris water maze at 300 mg/kg
Cayman Chemical 3EthylmethcathInonhydroch 10mg
A potential stimulant/entactogen designer drug of the amphetamine, phenethylamine, and cathinone chemical classes; intended for forensic purposes
ABclonal Technology Phospho-IRAK4-Ser346
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways The protein is essential for most innate immune responses Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease Multiple transcript variants encoding different isoforms have been found for this gene
Cayman Chemical UR144 N 5chloropentyl na 10mg
Differs from UR-144 by having a chlorine atom on the terminal carbon of the alkyl group; intended for research and forensic applications
Cayman Chemical AcetoxyvalerenIc AcId 10mg
A sesquiterpenic acid; cytotoxic to GLC-4 and COLO 320 cells (IC50s = 111 and 124 µM, respectively)
Cayman Chemical MtAhydrochlorIde 10mg
A designer drug that features a carbonyl group adjacent to a phenyl group, similar to cathinones; also marketed as mephtetramine; intended for forensic and research applications
Cayman Chemical CostunolIde 10mg
A natural sesquiterpene lactone that reduces growth (EC50 = 3-35 μM) and induces apoptosis in assorted cancer cell lines; inhibits the activation of Akt (15 μM) in endometriotic epithelial cells and STAT3 activation in THP-1 cells (EC50 = 10 μM); inhibits telomerase activity in NALM-6 cells