Bioactive Small Molecules
Medchemexpress LLC HY-10585A 500mg Medchemexpress, Valproic acid (sodium salt) CAS:1069-66-5 Purity:>98%
Medchemexpress, HY-10585A 500mg Valproic acid (sodium salt) CAS:1069-66-5 Valproic acid sodium salt (Sodium Valproate) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium salt activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-105129 10mg Medchemexpress, Pimonidazole (hydrochloride) CAS:70132-51-3 Purity:>98%
Medchemexpress, HY-105129 10mg Pimonidazole (HCl) CAS:70132-51-3 Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor. Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-108829 1mg Medchemexpress, Abatacept CAS:332348-12-6 Purity:>98%
Medchemexpress, HY-108829 1mg Abatacept CAS:332348-12-6 Abatacept (CTLA4lg) is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains). Abatacept is a selective T-cell co-stimulation modulator and a protein drug for the autoimmune diseases. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-119932 5mg Medchemexpress, PROTAC FAK degrader 1 CAS:2301916-69-6 Purity:>98%
Medchemexpress, HY-119932 5mg PROTAC FAK degrader 1 CAS:2301916-69-6 PROTAC FAK degrader 1 is a selective and potent focal adhesion kinase (Fak) degrader with an IC50 of 6.5 nM, DC50 of 3 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-119502 5mg Medchemexpress, Camalexin CAS:135531-86-1 Purity:>98%
Medchemexpress, HY-119502 5mg Camalexin CAS:135531-86-1 Camalexin is a phytoalexin isolated from Camelina sativa and Arabidopsis (Cruciferae) with antibacterial, antifungal, antiproliferative and anticancer activities. Camalexin can induce reactive oxygen species (ROS) production[3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-122218 1mg Medchemexpress, JHU-083 CAS:1998725-11-3 Purity:>98%
Medchemexpress, HY-122218 1mg JHU-083 CAS:1998725-11-3 JHU-083 is a selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b+ cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-112134 1mg Medchemexpress, CSN5i-3 CAS: Purity:>98%
Medchemexpress, HY-112134 1mg CSN5i-3 CAS: CSN5i-3 is a potent, selective and orally available inhibitor of CSN5, and inhibits CSN-catalysed Cul1 deneddylation with an IC50 value of 5.8 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-114153 10mg Medchemexpress, PLX5622 CAS:1303420-67-8 Purity:>98%
Medchemexpress, HY-114153 10mg PLX5622 CAS:1303420-67-8 PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor with an Ki of 5.9 nM, for extended and specific microglial elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-119706 1mg Medchemexpress, Barbadin CAS:356568-70-2 Purity:>98%
Medchemexpress, HY-119706 1mg Barbadin CAS:356568-70-2 Barbadin is a novel and selective β-arrestin/β2-adaptin interaction inhibitor, has IC50 values of 19.1 μM for β-arrestin1 and 15.6 μM for β-arrestin2. Barbadin blocks agonist-promoted endocytosis of the prototypical β2-adrenergic, V2-vasopressin and angiotensin-II type-1 receptors. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-113071A 5mg Medchemexpress, Mevalonic acid (lithium salt) CAS: Purity:>98%
Medchemexpress, HY-113071A 5mg Mevalonic acid (lithium salt) CAS: Mevalonic acid lithium salt, a precursor in the mevalonate pathway, is essential for cell growth and proliferation. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-114855 50mg Medchemexpress, BT2 CAS:34576-94-8 Purity:>98%
Medchemexpress, HY-114855 50mg BT2 CAS:34576-94-8 BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain α-ketoacid dehydrogenase complex (BCKDC). BT2 (compound 4) is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-120691A 5mg Medchemexpress, GSK205 CAS:1263068-83-2 Purity:>98%
Medchemexpress, HY-120691A 5mg GSK205 CAS:1263068-83-2 GSK205 is a potent, selective TRPV4 antagonist with an IC50 of 4.19 μM for inhibiting TRPV4-mediated Ca2+ influx. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-114409 5mg Medchemexpress, GB1107 CAS:1978336-61-6 Purity:>98%
Medchemexpress, HY-114409 5mg GB1107 CAS:1978336-61-6 GB1107 is a potent, selective, orally active inhibitor of Galectin-3 (Gal-3) with a Kd of 37 nM for human Galectin-3. GB1107 reduces human and mouse lung adenocarcinoma growth and blocks metastasis in the syngeneic model. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-111549 5mg Medchemexpress, Bragsin1 CAS:369631-68-5 Purity:>98%
Medchemexpress, HY-111549 5mg Bragsin1 CAS:369631-68-5 Bragsin1 is a potent, selective and noncompetitive inhibitor of the ArfGEF BRAG2, inhibits Arf GTPase activation, with an IC50 of 3 μM. Bragsin1 binds to PH domain of BRAG2, and is a noncompetitive interfacial inhibitor. Bragsin1 has no effect on the Sec7 domain of human ArfGEFs. Anti-cancer activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Abcam AMG 9810, TRPV1 receptor antagonist, 50MG
MW 337.4 Da, Purity >99%. Potent, selective, competitive vanilloid TRPV1 receptor antagonist (IC₅₀ = 17 nM). Inhibits capsaicin-, proton-, heat- and endogenous ligand-induced activation of human and rat recombinant TRPV1 receptors. Active in vitro and in vivo. See similar compounds
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