Bioactive Small Molecules
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Filtered Search Results
Selleck Chemical LLC MYF-01-37 S8950-25MG
MYF-01-37 is a novel covalent inhibitor of TEAD targeting Cys380 when incubated with the TEAD2 protein
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Medchemexpress LLC Corticotropin-releasing factor (human) | 86784-80-7 | 99.1% | 4757.45 | 10 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Corticotropin-releasing factor human (Human CRF) stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary. It is for research use only and not for sale to patients.
- Appearance: Solid
- Color: White to off-white
- Sequence: Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-R-Lys-Leu-Met-Glu-Ile-Ile-NH2
- Soluble in DMSO at 25 mg/mL
- Ships at room temperature in continental US
- Sealed storage, away from moisture and light, under nitrogen. Powder stable for 2 years at -80°C, 1 year at -20°C. In solvent, stable for 6 months at -80°C, 1 month at -20°C.
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TARGETMOL CHEMICALS INC JNJ-54175446 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. JNJ-54175446 (JNJ-5446) is a CNS-permeable and selective P2X7 receptor antagonist that attenuates the release of IL-1beta/IL-18 from microglia, and may be used in the study of depression. Purity 99.83%
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Medchemexpress LLC Rabusertib (LY2603618) | 911222-45-2 | 99.98% | 436.30 | 1 ML
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Rabusertib (LY2603618) is a potent and selective Chk1 inhibitor with an IC50 of 7 nM. It effectively reduces Chk1 autophosphorylation and abrogates the G2/M DNA damage checkpoint in cells treated with DNA damaging agents. Inhibition of Chk1 by Rabusertib leads to impaired DNA synthesis, elevated H2A.X phosphorylation, and premature entry into mitosis.
- Potent and selective inhibitor of Chk1 (IC50 of 7 nM)
- Reduces Chk1 autophosphorylation (EC50 of 430 nM)
- Abrogates G2/M DNA damage checkpoint
- Impairs DNA synthesis
- Elevates H2A.X phosphorylation
- Induces premature entry into mitosis
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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TARGETMOL CHEMICALS INC Glutaminyl Cyclase Inhibitor 1
Also available in 1 mL, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Glutaminyl Cyclase Inhibitor 1, a glutaminyl cyclase inhibitor with an IC50 of 0.5 uM, can be utilized for studying neurological disorders. Purity 100%
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Selleck Chemical LLC Atractylodis Rhizoma Extract E3075-5MG
Atractylodis Rhizoma Extract is extracted from Atractylodes macrocephala which has functions including treating hypofunction of the spleen with the loss of appetite abdominal distension diarrhea phlegm drink dizziness palpitation edema fetal movement restless
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Selleck Chemical LLC Zabedosertib E2837-5MG
Zabedosertib (BAY 1834845) is a IRAK4 inhibitor with immunomodulatory potential which is a protein kinase involved in signaling innate immune responses from Toll-like receptors
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Apexbio Technology LLC Paliperidone, 100mg. Cas: 144598-75-4 MFCD: MFCD00871802. Dopamine receptor antagonist
Paliperidone is a SR (5-HT2) receptor antagonist and D2DR inhibitor. Other sizes are available. Please inqury us for quote.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Apexbio Technology LLC Paliperidone, 25mg. Cas: 144598-75-4 MFCD: MFCD00871802. Dopamine receptor antagonist
Paliperidone is a SR (5-HT2) receptor antagonist and D2DR inhibitor. Other sizes are available. Please inqury us for quote.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Selleck Chemical LLC Ipragliflozin L-Proline S0994-25MG
Ipragliflozin L-Proline is an orally active and selective inhibitor of SGLT2 with IC50 of 7 38 nM 6 73 nM and 5 64 nM for human SGLT2 rat SGLT2 and mouse SGLT2 respectively
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Selleck Chemical LLC Estramustine E4897-100MG
Estramustine(NSC-89201 LEO275) is used to treat hormone-resistant prostate cancer and stabilize microtubule dynamics It acts as an anti-mitotic and anti-microtubule agent and disrupts microtubule disassembly It inhibits the binding of MAPs 1 and 2 to taxol-stabilized microtubules hinders microtubule assembly and promotes the disassembly of MAP-2-associated microtubules
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Sigma Aldrich Fine Chemicals Biosciences KY-05009 >=98% (HPLC) | 1228280-29-2 | 25MG
KY-05009 >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 352.41 | 1228280-29-2 | 25MG
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Enzo Life Sciences Coumestrol (5 mg). CAS: 479-13-0
Phytoestrogen. Acts as an estrogen agonist. Purity: ≥95% (HPLC). Solubility: Soluble in DMSO (25mg/ml) and warm ethanol (5 mg/ml). Long Term Storage: Ambient.
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Cayman Chemical TAK-981, Purity: ≥95% (mixture of isomers), CAS: 1858276-04-6, 1 mg
An inhibitor of SAE (IC50 = in vitro; decreases intratumor levels of SUMOlyated proteins and reduces tumor growth in an A20 syngeneic lymphoma mouse model
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Selleck Chemical LLC MYCi361 S8905-25MG
MYCi361 is a MYC inhibitor that engages MYC inside cells disrupts MYC/MAX dimers and impairs MYC-driven gene expression MYCi361 binds to MYC with Kd of 3 2 M MYCi361 suppresses in vivo tumor growth increases tumor immune cell infiltration upregulates PD-L1 on tumors and sensitizes tumors to anti-PD1 immunotherapy
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