Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

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5,311 – 5,325 of 60,541 results

5,311

Medchemexpress LLC O=[N+](C1=CC2=C(N(CC3=CC=CC=C3)N=C2OCC4CCCCC4)C=C1)[O-] | 1564253-75-3 | 99.7% | 365.43 | C21H23N3O3 | 5 MG

PGN36 is a selective cannabinoid CB2 receptor antagonist used as a research tool in neurobiology and bone biology. It shows high affinity for CB2R and is reported to cross the blood-brain barrier, making it suitable for in vivo and in vitro studies of neurodegeneration and collagen type I regulation.

Selective CB2 receptor antagonist (Ki 0.09 μM)
Marked selectivity over CB1 receptor (>40 μM)
Used in studies of frontotemporal dementia and bone-related assays
Molecular formula C21H23N3O3; molecular weight 365.43 g·mol-1
Purity 99.74%
Appearance light yellow solid
Storage: powder -20°C; in solvent -80°C for 6 months or -20°C for 1 month
Available in small research pack sizes such as 5 mg

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5,312

Medchemexpress LLC Benzoic acid, 4-[(3aS,4R,9bR)-6-ethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]- | 1357248-83-9 | 98.7% | 335.40 | 5 MG

Benzoic acid, 4-[(3aS,4R,9bR)-6-ethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]- | 1357248-83-9 | 98.7% | 335.40 | 5 MG

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5,313

Cayman Chemical MLN0905, Purity: ≥98%, CAS: 1228960-69-7, 5 mg

A Plk1 inhibitor (IC50 = 2 nM); inhibits 95% of Plk1 activity but also inhibits the activity of 10 additional kinases by greater than or equal to 90% in a panel of 359 kinases at 1 µM; reduces H3S10Ph in HT-29 colorectal cancer cells (EC30 = 9 nM); inhibits proliferation in a panel of six human lymphoma cell lines (IC50 = 3.2-24 nM)

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5,314

Medchemexpress LLC Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate | 15991-13-6 | MFCD01463811 | 97.4% | 234.20 g/mol | C12H10O5 | 25 MG

Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate is a coumarin-class small molecule used as a fluorescent probe and synthetic intermediate in chemical and biological research. Supplied as a solid with high listed purity, it is intended for analytical assays, fluorescence-based applications, and lab-scale synthesis.

Solid, white to light yellow appearance.
High purity suitable for analytical and synthetic use.
Coumarin-derived structure with fluorescent properties.
Available in multiple milligram packaging sizes for lab-scale work.
Provided with standard chemical identifiers for reproducibility.

Pricing & Availability

5,315

Medchemexpress LLC 2H-Dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide, 1,5-dihydro-2-imino-10-methyl-N-[3-(4-morpholinyl)propyl]- | 99.7% | 573.51 | 50 MG

SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM. It can suppress SPOP activity, which then increases the suppression of cancer substrate protein PTEN and DUSP7 content. In vivo, it can slow down tumor growth by suppressing SPOP. For research use only. We do not sell to patients.

In vitro, SPOP-IN-6b shows IC50s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, OS-RC-2, and 786-0 cells.
In vitro, SPOP-IN-6b can suppress SPOP activity, leading to an increase in suppression cancer substrate protein PTEN and DUSP7 content.
In vivo, SPOP-IN-6b can slow down the growth of tumor by suppressing SPOP.

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5,316

AG Scientific Inc TCEP Hydrochloride, 5 G

TCEP hydrochloride is a non-thiol reducing agent used to reduce and break disulfide bonds. TCEP HCl is widely preferred to the similar reducing agent DTT because of its greater effectiveness and resistance to oxidation from air exposure.CAS Number: 51805-45-9Molecular Weight: 286.6 DaChemical Formula: C9H15O6P HClSolubility: Soluble in waterStorage Temperature: -20CResearch or further manufacturing use only, not for food or drug use.

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5,317

Medchemexpress LLC HY-105040C 5mg Medchemexpress, Pomaglumetad methionil (hydrochloride) CAS:635318-26-2 Purity:>98%

Medchemexpress, HY-105040C 5mg Pomaglumetad methionil (hydrochloride) CAS:635318-26-2 Pomaglumetad methionil hydrochloride (LY2140023 hydrochloride) is an orally active, methionine prodrug of the selective mGlu2/3 receptor agonist LY404039. Pomaglumetad methionil hydrochloride has the potential for schizophrenia research. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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5,318

Medchemexpress LLC Ccx-777 | 1226686-36-7 | 98.5% | 593.78 g/mol | C31H43N7O3S | 10MG

CCX-777 is a small-molecule partial agonist of β-arrestin-2 recruitment to ACKR3 (atypical chemokine receptor 3), provided as a purified research compound for in vitro and preclinical studies. The compound has formula C31H43N7O3S and a molecular weight of 593.78 g/mol.

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5,319

Cayman Chemical DC-05, Purity: ≥98%, CAS: 890643-16-0, 10 mg

A non-nucleoside DNMT1 inhibitor (IC50 = 10.3 µM); selective for DNMT1 over DNMT3A and DNMT3B (IC50s = >200 µM), as well as G9a, SUV39H1, MLL1, SET7/9, and PRMT1 (IC50s = >150, >150, >150, >150, and 37.1 µM, respectively); reduces proliferation of HCT116 colon cancer cells from 2.5-10 µM

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5,320

Cayman Chemical Arylquin 1, Purity: ≥98%, CAS: 1630743-73-5, 5 mg

A Par-4 secretagogue; binds to vimentin to displace Par-4 for secretion; induces Par-4 secretion from MEFs and prostate cancer cells in vitro; induces paracrine apoptosis of H1299, HOP92, and H460 cancer cells when co-cultured with Par-4+/+ MEFs

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5,321

Selleck Chemical LLC Marinopyrrole A (Maritoclax) 5mg 1227962-62-0

Marinopyrrole A (Maritoclax) is a selective Mcl-1 antagonist. It binds to Mcl-1, but not Bcl-XL, and targets Mcl-1 for proteasomal degradation. Maritoclax disrupts the interaction between Bim and Mcl-1 with an IC50 of 10.1 ?M. *For Research & Development use only. Product is not intended for drug, household, or human consumption.

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5,322

Amsbio LLC Stemolecule Doxycycline hyclate (10 mg)

Stemolecule Doxycycline hyclate (10 mg)

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5,323

Cayman Chemical Dehydrocannabifuran, Purity: ≥95%, CAS: 56154-59-7, 5 mg

An analytical reference standard that is structurally similar to known phytocannabinoids; has been found in Cannabis and marijuana smoke condensate; intended for research and forensic applications

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5,324

Medchemexpress LLC Quipazine (maleate) | 5786-68-5 | 98.0% | 25 MG

Quipazine maleate is a chemical compound that acts as a 5-HT agonist, known to cause behavioral changes like hyperactivity. It also exhibits weak reversible MAO inhibitory activity.

5-HT receptor agonist
Causes behavioral changes such as hyperactivity
Shows weak reversible MAO inhibitory activity
For research use only
Store at 4°C in sealed container, away from moisture and light
In solvent, store at -80°C for 6 months or -20°C for 1 month

Pricing & Availability

5,325

Apexbio Technology LLC Dacomitinib (PF299804, PF299), 5mg. Cas: 1110813-31-4 MFCD: MFCD19443734. HER inhibitor

IC50: 6 nM (EGFR); 45.7 nM (ERBB2); 73.7 nM (ERBB4)The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Other sizes are available. Please inqury us for quote.

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Medchemexpress LLC O=[N+](C1=CC2=C(N(CC3=CC=CC=C3)N=C2OCC4CCCCC4)C=C1)[O-] | 1564253-75-3 | 99.7% | 365.43 | C21H23N3O3 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Benzoic acid, 4-[(3aS,4R,9bR)-6-ethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]- | 1357248-83-9 | 98.7% | 335.40 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate | 15991-13-6 | MFCD01463811 | 97.4% | 234.20 g/mol | C12H10O5 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2H-Dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide, 1,5-dihydro-2-imino-10-methyl-N-[3-(4-morpholinyl)propyl]- | 99.7% | 573.51 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-105040C 5mg Medchemexpress, Pomaglumetad methionil (hydrochloride) CAS:635318-26-2 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ccx-777 | 1226686-36-7 | 98.5% | 593.78 g/mol | C31H43N7O3S | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Amsbio LLC Stemolecule Doxycycline hyclate (10 mg) Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Quipazine (maleate) | 5786-68-5 | 98.0% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More