Bioactive Small Molecules
Cayman Chemical L-ArgInIn-13C6hydrochlorId 5mg
An internal standard for the quantification of L-arginine by GC- or LC-MS
Cayman Chemical ANTIBODY IfosfamIde 1g
A nitrogen mustard alkylating agent used as a chemotherapeutic agent against advanced transitional cell carcinoma; serves as a prodrug that is metabolized to its active DNA alkylating form, isophosphoramide mustard
Cayman Chemical ANTIBODY DOPAL 5mg
An aldehyde product of the oxidative deamination of dopamine that is toxic to neurons
Medchemexpress LLC 3-methoxyisoquinoline-1-carboxylic acid | 374917-64-3 | MFCD01845410 | 99.6% | 203.20 g/mol | C11H9NO3 | 100 MG
3-methoxyisoquinoline-1-carboxylic acid is a small-molecule chemical intermediate used for the synthesis of various active compounds and research reagents. It is supplied for research use only and is not intended for human or clinical use.
- Chemical identity: 3-methoxyisoquinoline-1-carboxylic acid
- Cas number: 374917-64-3
- Chemical formula: C11H9NO3
- Molecular weight: 203.20 g/mol
- Typical purity: 99.6% (HPLC, batch COA)
- Storage recommendations: room temperature for solid (recommended up to 3 years); in solvent store at -20°C to -80°C for extended stability
- Intended use: chemical/drug intermediate for research and synthesis
Medchemexpress LLC Deltasonamide 2 hydrochloride | 2448341-55-5 | 99.8% | 1 ML
Deltasonamide 2 hydrochloride is the hydrochloride salt of a small-molecule inhibitor that binds phosphodiesterase δ (PDEδ) with high affinity (Kd ≈ 385 pM). It is supplied as a solid or as a ready-to-use 10 mM solution in DMSO for research use; handle according to safety documentation.
- Competitive, high-affinity PDEδ inhibitor (Kd ≈ 385 pM).
- Hydrochloride salt to improve solubility for biological assays.
- Available as solid and as a 10 mM solution in DMSO (1 mL).
- High purity, typically 99.78%.
- Molecular weight 683.71 g/mol; formula C30H40Cl2N6O4S2.
![Medchemexpress LLC 1,2,5-oxadiazole-3-carboxylic acid, 4-amino-, 2-(9H-indeno[1,2-e]oxadiazolo[3,4-b | 354543-09-2 | 97.4% | 1MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000231628.png-250.jpg)
Medchemexpress LLC 1,2,5-oxadiazole-3-carboxylic acid, 4-amino-, 2-(9H-indeno[1,2-e]oxadiazolo[3,4-b | 354543-09-2 | 97.4% | 1MG
1,2,5-oxadiazole-3-carboxylic acid, 4-amino-, 2-(9H-indeno[1,2-e]oxadiazolo[3,4-b | 354543-09-2 | 97.4% | 1MG
![Medchemexpress LLC [Glu1]-Fibrinopeptide B | 103213-49-6 | 98.3% | 1570.57 | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000424995.png-250.jpg)
Medchemexpress LLC [Glu1]-Fibrinopeptide B | 103213-49-6 | 98.3% | 1570.57 | 1 MG
[Glu1]-Fibrinopeptide B | 103213-49-6 | 98.3% | 1570.57 | 1 MG
Medchemexpress LLC Katacalcin (TFA) | 85916-47-8 | MFCD00133425 | 99.6% | 2550.62 | 5 MG
Katacalcin TFA (PDN 21 TFA) is a potent peptide that lowers plasma calcium levels. It belongs to the calcitonin family, inducing a rapid, short-lived decrease in blood calcium and phosphate by promoting their bone incorporation.
- Solid, white to off-white appearance
- Potent plasma calcium-lowering peptide
- Causes rapid, short-lived drop in blood calcium and phosphate levels
- More potent inhibitor of fMLP-induced chemotaxis than calcitonin or procalcitonin
- Deactivates CD14+ peripheral blood mononuclear cell (PBMC) chemotaxis
- Regulates human CD14+ PBMC migration via protein kinase A-dependent cAMP pathways
Medchemexpress LLC Palmitoyl tripeptide-38 | 1447824-23-8 | 99.8% | 675.96 | 5 MG
Palmitoyl tripeptide-38 is a bioactive peptide known for its anti-aging properties. It functions by targeting Reactive Oxygen Species (ROS) and plays a role in immunology/inflammation, metabolic enzyme/protease, and NF-κB pathways.
- Bioactive peptide with anti-aging effect
- Targets Reactive Oxygen Species (ROS)
- Involved in immunology/inflammation pathways
- Involved in metabolic enzyme/protease pathways
- Involved in NF-κB pathways
STEMCELL Technologies IWP-2, Size: 1 mg
IWP-2 inhibits the WNT pathway (IC₅₀ = 27 nM) at the level of the pathway activator Porcupine. Porcupine is a membrane-bound acyltransferase that palmitoylates WNT proteins, which leads to WNT secretion and signaling capability. (Chen et al., Willert et al.)DIFFERENTIATION· Suppresses self-renewal of mouse embryonic stem (ES) cells and supports their conversion to epiblast-like stem cells (ten Berge et al.).· Inhibits maintenance and proliferation of mouse Lgr5+ intestinal and cochlear epithelial stem cells, demonstrating the importance of WNT signaling in these processes (Chai et al., Farin et al.).· Promotes cardiomyocyte differentiation from human pluripotent stem cells (Lian et al., Minami et al.).
Selleck Chemical LLC Avitinib maleate E4597-1G
Avitinib maleate(Abivertinib maleate AC0010 maleate AC0010MA) is a third-generation irreversible and orally active selective inhibitor of EGFR It displays IC50 values of 0 18 nM 0 18 nM 7 68 nM and against EGFR L858R EGFR T790M and wild-type EGFR Avitinib maleate also acts as an inhibitor of BTK that induces apoptosis of BTK in mantle cell lymphoma
Selleck Chemical LLC NADP E7274-50MG
NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism which is alternately oxidized (NADP ) and reduced (NADPH) and can maintain cellular redox homeostasis and regulate many biological events including cellular metabolism NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance NADPH plays a multifunctional role in regulating inflammation redox homeostasis and synthetic metabolism processes
Medchemexpress LLC PF-04745637 | 1917294-46-2 | 100.0% | 1 ML
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM for human TRPA1. It is supplied for research use in solution (10 mM in DMSO, 1 mL) and as multiple solid quantities for laboratory studies. Storage recommendations are provided to preserve stability.
- Potent TRPA1 inhibition with IC50 17 nM.
- High purity suitable for research applications.
- Available as 10 mM solution in DMSO and multiple solid sizes.
- Recommended storage conditions for powder and solution to maintain stability.
- Intended for in vitro and topical pharmacology studies.
Medchemexpress LLC Sulfuric acid ammonium salt (1:2) | 7783-20-2 | 99.3% | 132.14 | 100 G
Ammonium sulphate is an inorganic sulfate salt primarily used in molecular biology for applications such as precipitating proteins, separating antibodies, and enhancing antigen-antibody reactions. It also functions as a nitrogen source in plant fertilizers and has been observed to impact freshwater snails and mosquito larvae in rice paddies, as well as inhibit glucose conversion to ascorbic acid in plants. For research use only.
- Used for molecular biology applications
- Precipitates proteins
- Separates antibodies
- Enhances antigen-antibody reactions
- Serves as a nitrogen source in plant fertilizers
- Exhibits developmental toxicity to freshwater snails
- Increases *Anopheles africanus* and *Culex* mosquito larvae populations
- Inhibits the conversion of glucose to ascorbic acid in plants
Medchemexpress LLC Hydrocortisone 21-hemisuccinate sodium | 125-04-2 | 99.7% | 100 MG
Hydrocortisone hemisuccinate sodium is an orally active physiological glucocorticoid that inhibits proinflammatory cytokine activity, with IC50s of 6.7 μM for IL-6 and 21.4 μM for IL-3. This compound can be used for the research of ulcerative colitis (UC).
- Orally active physiological glucocorticoid
- Inhibits proinflammatory cytokine activity (IL-6 and IL-3)
- Can be used for research of ulcerative colitis (UC)
- Reduces weight loss and increases food intake in mice at 30 mg/kg dosage
- Significantly decreased disease activity index (DAI) scores and myeloperoxidase (MPO) activity in a rat model of colitis