Bioactive Small Molecules
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Filtered Search Results
Medchemexpress LLC Corticosterone-d4 | 2243253-91-8 | 99.2% | 1 MG
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Corticosterone-d4 is the deuterium labeled Corticosterone. Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Selleck Chemical LLC AS2863619 S8903-100MG
AS2863619 is a small-molecule cyclin-dependent kinase CDK8/19 inhibitor with IC50 of 0 6099 nM and 4 277 nM respectively AS2863619 is a potent Foxp3 inducer in Tconv cells
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Selleck Chemical LLC PF-07799933 E4681-5MG
PF-07799933 (Claturafenib ARRY-440) is a brain-penetrant selective pan-mutant inhibitor of BRAF It exhibits broad inhibition of pERK levels in HT29 cells with an IC50 value of 1 6 nM PF-07799933 treatment displays antitumor activity against BRAFV600- and non-V600-mutant cancers preclinically and in treatment-refractory patients
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Selleck Chemical LLC W-7 hydrochloride E4636-5MG
W-7 hydrochloride is a potent antagonist of calmodulin (CaM) that inhibits Dengue virus (DENV) translation and replication It also competitively inhibits Trypsin-treated Ca2 /calmodulin-dependent phosphodiesterase (Ca2 -PDE) It exhibits anti-proliferative and anti-tumor effect
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Cayman Chemical Lipid CL1, Purity: ≥95%, CAS: 1450888-71-7, 5 mg
An ionizable cationic trialkyl lipid; has been used in the formation of LNPs for delivering mRNA in vivo; LNPs containing lipid CL1 and encapsulating mRNA encoding human EPO increase blood EPO protein levels in mice; LNPs containing lipid CL1 and encapsulating mRNA encoding a reporter protein increase reporter expression in the liver in mice; LNPs containing lipid CL1 and encapsulating mRNA encoding influenza A HA increase serum anti-HA IgG antibody titers in a mouse model of HA vaccination
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Medchemexpress LLC Loncastuximab tesirine, (Synonyms: Loncastuximab tesirine-lpyl; ADCT-402), 500ug
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Loncastuximab tesirine is a human cluster of differentiation 19 (CD19)-directed antibody-drug conjugate (ADC). Once bound to CD19 on the cell membrane, loncastuximab tesirine is rapidly internalised and triggers cell death. Loncastuximab tesirin induces cell apoptosis, it can be used for the research of diffuse large B-cell lymphoma.
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![Medchemexpress LLC (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylene]-3,5-dihydro-2-methyl-3-(2,2,2-trifluoroethyl)-4h-imid | 1539318-36-9 | MFCD29081187 | 98.1% | 320.21 g/mol | C13H9F5N2O2 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000263676.png-250.jpg)
Medchemexpress LLC (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylene]-3,5-dihydro-2-methyl-3-(2,2,2-trifluoroethyl)-4h-imid | 1539318-36-9 | MFCD29081187 | 98.1% | 320.21 g/mol | C13H9F5N2O2 | 5 MG
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DFHBI-1T is a membrane-permeable RNA-aptamer-activated fluorescent probe that produces bright, low-background fluorescence (ex/em = 472 nm/507 nm) when bound to target RNA aptamers. Supplied as a light-yellow solid with high purity, it is suitable for live-cell RNA imaging and in vitro fluorescence assays.
- Membrane-permeable fluorophore suited for live-cell imaging
- Activates fluorescence upon binding specific RNA aptamers, reducing background
- Excitation/emission maxima approximately 472 nm/507 nm
- High purity for reproducible experimental results
- Solid form with convenient small-scale packaging for assay development
- Compatible with common fluorescence filter sets
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Selleck Chemical LLC TGR5 Receptor Agonist S0193-25MG
TGR5 Receptor Agonist (TGR5 CCDC MDK00245 compd 6) is a potent agonist of TGR5(GPCR19 GPBAR1 M-BAR) TGR5 Receptor Agonist shows improved potency with pEC50 of 6 8 and 7 5 in the U2-OS cell assay and in melanophore cells respectively
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Selleck Chemical LLC Sodium picosulfate monohydrate E4854-25MG
Sodium picosulfate monohydrate is a polyphenolic stimulant laxative and prodrug form of desacetyl bisacodyl (DAB) It is used for treating idiopathic constipation and preparing the bowel before colonoscopy
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Selleck Chemical LLC JHU-083 S8891-25MG
JHU-083 (Ethyl 2-(2-Amino-4-methylpentanamido)-DON) is a novel prodrug of DON JHU-083 selectively blocks glutaminase activity in brain CD11b cells and prevents depression-associated behaviors induced by chronic social defeat stress Solutions are unstable and should be fresh-prepared
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Selleck Chemical LLC Naporafenib S8745-25MG
Naporafenib (LXH254) is a type II ATP-competitive inhibitor that inhibits both B- and CRAF kinase activities at picomolar concentrations with a high degree of selectivity against a panel of 456 human kinases and in cell-based assays
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Selleck Chemical LLC Catalase Aspergillus niger E7315-100MG
Catalase Aspergillus niger is a key enzyme in the metabolism of H2O2 and reactive oxygen species (ROS) and its expression and localization is markedly altered in tumors Free oxygen radical scavenger
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Selleck Chemical LLC Rimonabant hydrochloride E4858-1G
Rimonabant hydrochloride (SR 141716A hydrochloride) is a highly potent and selective antagonist of the central cannabinoid receptor (CB1) with a Ki of 1 8 nM It is an anorectic anti-obesity drug with potential to treat obesity and cardiovascular risk factors
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Cayman Chemical pythiDC, Purity: ≥98%, CAS: 1821370-71-1, 10 mg
A CP4H1 inhibitor (IC50 = 4 µM); selective for CP4H1 over HIF-PH2 at 10 µM
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Medchemexpress LLC Spiroxamine | 118134-30-8 | 99.9% | 50MG
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Spiroxamine | 118134-30-8 | 99.9% | 50MG
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