Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

Search Within Results

6,661 – 6,675 of 60,541 results

6,661

Cayman Chemical 3,4-Dicaffeoylquinic Acid, Purity: ≥98%, CAS: 14534-61-3, 5 mg

A polyphenol with diverse biological activities; inhibits ACE and α-glucosidase; reduces mutagenicity of Trp-P-1 against S. typhimurium by 59% at 0.57 mM; has antioxidant activity in ferric reducing, β-carotene bleaching, and DPPH scavenging assays (EC50s = 2.18, 23.85, and 68.91 μg/ml, respectively); cytotoxic to NCI-H23 lung adenocarcinoma cells (EC50 = 3.26 μg/ml); increases TRAIL mRNA, decreases H1N1 HA mRNA, and increases survival in a mouse model of influenza A infection

Pricing & Availability

6,662

Cayman Chemical Ginsenoside Ro, Purity: ≥98%, CAS: 34367-04-9, 5 mg

A non-steroid glycoside with diverse biological activities; inhibits LPS-induced ROS and NO release as well as iNOS and COX-2 protein expression in RAW 264.7 mouse macrophages at 200 μM; dose-dependently inhibits thrombin-induced human platelet aggregation in vitro and thrombin-induced DIC in rats at 100 mg/kg; increases the 20-day survival of Sendai virus-infected mice at 1 mg per day for three days prior to infection; stimulates hair regrowth after shaving in a mouse model of slowed hair regrowth at 0.2 mg per animal topically

Pricing & Availability

6,663

Cayman Chemical Lodoxamide, Purity: ≥95%, CAS: 53882-12-5, 50 mg

A potent agonist of GPR35 (EC50 = 1.61 nM); inhibits histamine release in isolated rat peritoneal mast cells (IC50s = 0.1-50 µM); inhibits A23187-induced calcium influx in isolated rat mast cells; reduces antigen-induced histamine release from rat conjunctival tissue by 46% in vitro when used at a concentration of 10 µg/ml; dose-dependently reduces the immediate hypersensitivity response in rat conjunctiva in vivo; reduces mast cell degranulation in rat conjunctiva

Pricing & Availability

6,664

Cayman Chemical BDP9066, Purity: ≥98%, CAS: 2226507-04-4, 1 mg

An inhibitor of MRCKα and MRCKβ (Kis = 0.0136 and 0.0233 nM, respectively); selective for MRCKα and MRCKβ over ROCK1 and ROCK2 (Kis = 18.4 and 5.38 nM, respectively) and a panel of 115 additional kinases at 1 µM; has antiproliferative activity against a panel of 757 cancer cell lines (EC50s = 50 = 64 nM); inhibits the motility of SCC-12 cells; decreases average papilloma volume in a mouse two-stage model of DMBA-initiated and TPA-promoted skin carcinogenesis at 25 µg/animal

Pricing & Availability

6,665

Cayman Chemical Adenosine 3',5'-diphosphate (sodium salt), Purity: ≥95%, CAS: 75431-54-8, 5 mg

An adenine nucleotide containing two phosphate groups; a product of PAPS; has been used to study the kinetic properties and structure of SULTs

Pricing & Availability

6,666

Cayman Chemical Hexanoyl-L-carnitine (chloride), Purity: ≥95%, CAS: 162067-53-0, 5 mg

A medium-chain acylcarnitine; has been used in the synthesis of acylcarnitine benzyl esters

Pricing & Availability

6,667

Cayman Chemical epi-Aszonalenin A, Purity: ≥95%, CAS: 908853-14-5, 5 mg

A benzodiazepine fungal metabolite

Pricing & Availability

6,668

Cayman Chemical Oroxylin A, Purity: ≥98%, CAS: 480-11-5, 5 mg

A flavonoid with diverse biological activities; inhibits poly(I:C)-induced decreases in cell viability and increases in NO production in RAW 264.7 macrophages at 5-25 μM; inhibits poly(I:C)-induced increases in IL-1α, IL-1β, GM-CSF, IL-6, IL-10, MCP-1, and TNF-α production in RAW 264.7 cells at 10-50 μM; inhibits hypoxia-induced migration and invasion of MCF-7, DU145, and HepG2 cells in wound healing and cell invasion assays, respectively, at 10 and 20 μM; an inhibitor of UGT1A1 (IC50 = 9.14 μM) and P-glycoprotein (IC50 = 78.3 μM); increases the cytotoxicity of the P-glycoprotein substrate paraquat in MDR1-MDCKII cells and paclitaxel in MX-1 and MX-1/T cells

Pricing & Availability

6,669

Cayman Chemical Cabotegravir, Purity: ≥98%, CAS: 1051375-10-0, 5 mg

An HIV-1 integrase inhibitor (IC50 = 3 nM in a strand transfer assay); inhibits HIV replication in MT-4 cells and PBMCs (IC50s = 1.3 and 0.2 nM, respectively); protective against SHIV infection in macaques at 50 mg/kg

Pricing & Availability

6,670

Cayman Chemical A-419259, Purity: ≥98%, CAS: 364042-47-7, 1 mg

An inhibitor of Src family kinases, including Src, LCK, Lyn, and Hck (IC50s = 9, 50 = 3,000 nM) and PKC (IC50 = >33 μM); inhibits growth of Ph+ K-562 and Meg-01 myeloid leukemia cells (IC50s = 0.1-0.3 and 0.1 μM, respectively), but not Ph- TF-1 and HEL cells; induces apoptosis in K-562 cells in a concentration-dependent manner; inhibits differentiation of murine embryonic stem cells while maintaining pluripotency at 300 nM; reduces the total number of AML cells, as well as AML stem cells, in the bone marrow and spleen of human patient-derived AML mouse xenograft models at 30 mg/kg twice daily

Pricing & Availability

6,671

Medchemexpress LLC HY-125880 5mg Medchemexpress, SBI-553 CAS:1849603-72-0 Purity:>98%

Medchemexpress, HY-125880 5mg SBI-553 CAS:1849603-72-0 SBI-553 is a potent and brain penetrant NTR1 allosteric modulator, with an EC50 of 0.34 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Pricing & Availability

6,672

Medchemexpress LLC HY-N4150 5mg Medchemexpress, Quercetagitrin CAS:548-75-4 Purity:>98%

Medchemexpress, HY-N4150 5mg Quercetagitrin CAS:548-75-4 Quercetagitrin (Quercetagetin-7-O-glucoside), isolated from the flowers of the African Marigold (Tagetes erecta), has anti-inflammatory activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Pricing & Availability

6,673

Medchemexpress LLC HY-126010 5mg Medchemexpress, Dooku1 CAS:2253744-54-4 Purity:>98%

Medchemexpress, HY-126010 5mg Dooku1 CAS:2253744-54-4 Dooku1, an analog of Yoda1, is a selective antagonist of the endogenous Piezo1 channel. Dooku1 inhibited 2 μM Yoda1-induced Ca2+-entry with IC50 values of 1.3 μM (in HEK 293 cells) and 1.5 μM (in HUVECs). Dooku1 inhibits Yoda1-induced relaxation of aorta. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Pricing & Availability

6,674

Medchemexpress LLC HY-16658B 5mg Medchemexpress, Z-VAD-FMK CAS:161401-82-7 Purity:>98%

Medchemexpress, HY-16658B 5mg Z-VAD-FMK CAS:161401-82-7 Z-VAD-FMK (Z-VAD(OH)-FMK) is a well-know pan caspase inhibitor, which does not inhibit ubiquitin carboxy-terminal hydrolase L1 (UCHL1) activity even at concentrations as high as 440 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Pricing & Availability

6,675

Medchemexpress LLC HY-126675 5mg Medchemexpress, AS2863619 (free base) CAS:2241300-50-3 Purity:>98%

Medchemexpress, HY-126675 5mg AS2863619 (free base) CAS:2241300-50-3 AS2863619 free base enables conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells for the treatment of various immunological diseases. AS2863619 free base is a potent, orally active cyclin-dependent kinase 8 (CDK8) and CDK19 inhibitor with IC50s of 0.61 nM and 4.28 nM, respectively. STAT5 activation enhanced by AS2863619 free base inhibition of CDK8/19, which consequently activates the Foxp3 gene. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Pricing & Availability

Bioactive Small Molecules

Filtered Search Results

Narrow Results

Medchemexpress LLC HY-125880 5mg Medchemexpress, SBI-553 CAS:1849603-72-0 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-N4150 5mg Medchemexpress, Quercetagitrin CAS:548-75-4 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-126010 5mg Medchemexpress, Dooku1 CAS:2253744-54-4 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-16658B 5mg Medchemexpress, Z-VAD-FMK CAS:161401-82-7 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-126675 5mg Medchemexpress, AS2863619 (free base) CAS:2241300-50-3 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-125880 5mg Medchemexpress, SBI-553 CAS:1849603-72-0 Purity:>98%

Medchemexpress LLC HY-N4150 5mg Medchemexpress, Quercetagitrin CAS:548-75-4 Purity:>98%

Medchemexpress LLC HY-126010 5mg Medchemexpress, Dooku1 CAS:2253744-54-4 Purity:>98%

Medchemexpress LLC HY-16658B 5mg Medchemexpress, Z-VAD-FMK CAS:161401-82-7 Purity:>98%

Medchemexpress LLC HY-126675 5mg Medchemexpress, AS2863619 (free base) CAS:2241300-50-3 Purity:>98%