Bioactive Small Molecules
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Filtered Search Results
Cayman Chemical GemIfloxacInmesylate 5mg
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A fluoroquinolone antibiotic that is effective against C. pneumoniae and M. tuberculosis (MIC50s = 0.25 and 8 UG/ml, respectively); useful against respiratory tract infections
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Medchemexpress LLC Ccr7 antagonist 1 | 3048330-48-6 | 99.55% | 310.42 | 25 MG
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CCR7 antagonist 1 is a dual CXCR2 and CCR7 antagonist, with IC50 values of 11.02 μM for CXCR2 and 0.43 μM for CCR7. This product is intended for research use only.
- Dual CXCR2 and CCR7 antagonist
- IC50 of 11.02 μM for CXCR2
- IC50 of 0.43 μM for CCR7
- Suitable for research applications
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AdipoGen SAG
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Chemical. CAS 912545-86-9. Formula C28H28ClN3OS. MW 490.1. Cell permeable Sonic hedgehog Shh agonist. Cell permeable smoothened Smo agonist. Induces Sonic hedgehog Shh pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro.
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Selleck Chemical LLC Wedelolactone S9042-5MG
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Wedelolactone a medicinal plant-derived natural compound is an inhibitor of IKK that is critical for activation of NF- B by mediating phosphorylation and degradation of I B Wedelolactone is also an inhibitor of caspase-11
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Selleck Chemical LLC Lobeliae Chinensis Extract E3049-5MG
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Lobeliae Chinensis Extract is extracted from Lobeliae Chinensis which is a traditional Chinese herb widely used in the treatment of diabetes and found to have a hypoglycaemic mechanism related to the inhibition of DPP4
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STEMCELL Technologies IDE2, Size: 5 mg
Inducer of definitive endoderm 2 (IDE2) induces differentiation of mouse or human pluripotent stem cells (PSCs) by activating SMAD2 phosphorylation and NODAL expression (Borowiak et al.). At EC₅₀ = 223nM, SOX17 expression was induced in mouse ES cells.DIFFERENTIATION· Induces definitive endoderm from mouse or human ES cells in the absence of Activin A, NODAL, or feeder cells (Borowiak et al.).
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![Medchemexpress LLC Benzo[a]phenazin-5-ol | 2089-82-9 | 99.5% | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000230652.png-250.jpg)
Medchemexpress LLC Benzo[a]phenazin-5-ol | 2089-82-9 | 99.5% | 25 MG
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sAJM589 is a small-molecule c-Myc inhibitor that disrupts the Myc-Max heterodimer and is supplied as a powdered research chemical (C16H10N2O, MW 246.26 g/mol) with high reported purity and a reported IC50 of 1.8 μM for Myc. Store powders frozen or refrigerated per supplier recommendations.
- Disrupts Myc-Max heterodimer, inhibiting c-Myc activity.
- Reported IC50 of 1.8 μM for Myc.
- High purity (99.47%), suitable for in vitro research.
- Available as a powder in multiple solid sizes and as a DMSO solution format.
- Stable when stored frozen according to supplier guidelines.
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Medchemexpress LLC HY-N6961 10mg Medchemexpress, Lapachol CAS:84-79-7 Purity:>98%
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Medchemexpress, HY-N6961 10mg Lapachol CAS:84-79-7 Lapachol is a naphthoquinone that was first isolated from Tabebuia avellanedae (Bignoniaceae). Lapachol shows anti-infection and antitumor activity Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC STM2457 S9870-10MM/1ML
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STM2457 is a highly potent and selective first-in-class catalytic inhibitor of RNA Methyltransferase METTL3 with an IC50 of 16 9 nM STM2457 is highly specific for METTL3 and showed no inhibition of other RNA methyltransferases
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Selleck Chemical LLC FDW028 E4732-25MG
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FDW028 is a highly potent and selective inhibitor of FUT8 FDW028 demonstrates strong anti-tumor effects by promoting defucosylation and inducing lysosomal degradation of B7-H3 via the chaperone-mediated autophagy (CMA) pathway Additionally FDW028 suppresses the AKT/mTOR signaling pathway FDW028 exhibits potent anti-Metastatic colorectal cancer (mCRC) activities
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Selleck Chemical LLC N-Desmethyl tamoxifen HCl E2368-5MG
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N-Desmethyltamoxifen hydrochloride (N-Desmethyl tamoxifen HCl) the primary metabolite of tamoxifen is an estrogen response modifer and protein kinase C inhibitor with IC50 of 25 M
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Cayman Chemical ResorcInolnaphthaleIn 5mg
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Increases the activity of angiotensin-converting enzyme 2 (ACE2) in vitro (EC50 = 19.5 μM)
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Med Vet International Chlorpheniramine Tablets 4mg, 1000 tablets
Chlorpheniramine Tablets 4mg, 1000 tabletsProducts are not always manufacturer specific. Actual product appearance may differ from website image.
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Medchemexpress LLC 4-tert-Butyl-benzhyd 50mg | 62034-73-5 | 193.24 g/mol | C11H15NO2 | 50 MG
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4-(tert-Butyl)-benzhydroxamic acid is a hydroxamic acid derivative used as a research reagent. It has been reported to act as a PqsR antagonist that modulates bacterial quorum sensing and reduces pyocyanin production in Pseudomonas aeruginosa. Supplied as a solid or as solution aliquots, it is intended for in vitro research use only.
- Reported PqsR antagonist activity with micromolar IC50s in bacterial assays.
- High purity (99.49%) suitable for research applications.
- Available as neat solid and 10 mM solutions in DMSO for screening and assays.
- Multiple pack sizes available for flexibility in experiments (for example, 5 mg, 10 mg, 50 mg).
- Chemical formula C11H15NO2; molecular weight 193.24 g/mol.
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Selleck Chemical LLC Dalasetron Mesylate Hydrate E4903-100MG
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Dolasetron Mesylate hydrate(MDL-73147EF hydrate) is an antagonist of serotonin 5-HT3 receptor It is used in the treatment of patients with nausea and vomiting following chemotherapy
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