Bioactive Small Molecules
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Filtered Search Results
Medchemexpress LLC Kc7F2-100Mg | HY-18777-100MG
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Kc7F2-100Mg
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Selleck Chemical LLC Oclacitinib E4971-5MG
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Oclacitinib(PF-03394197) an inhibitor of JAK is highly potent at inhibiting JAK1 with an IC50 value of 10 nM respectively Oclacitinib is highly potent against the JAK1 enzyme displaying a 1 8-fold selectivity for JAK1 vs JAK2 and a 9 9-fold selectivity toward JAK1 vs JAK3
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Cayman Chemical 4-oxo-2-Nonal Alkyn 5mg
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An alkyne-tagged electrophile that can be used as a probe to isolate and identify the reaction products of lipid peroxidation using click chemistry
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eMolecules 4291-63-8 | Medchem Express | Cladribine | 10mg | 446263188 | HY-13599 | 285.69 | C10H12ClN5O3
Ambeed | 2345-Tetrachloroanisole | 250mg | 686660236 | A540849 | 938-86-3 | MFCD00012240 | 245.910 | C7H4Cl4O
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Medchemexpress LLC (2S,5S)-Methyl 5-phenylpyrrolidine-2-carboxylate hydrochloride | 2170170-16-6 | MFCD22199190 | 99.85% | 241.71 | 1 G
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(2S,5S)-Methyl 5-phenylpyrrolidine-2-carboxylate hydrochloride is a drug intermediate for the synthesis of various active compounds.
- Drug intermediate for synthesis of various active compounds.
- Formula: C12H16ClNO2
- Research area: Others
- Target: Drug intermediate
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Cayman Chemical ONO-AE3-208 5mg
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An antagonist of the EP4 receptor (Ki = 1.3 nM) which less potently affects EP3, FP, and TP receptors (Kis = 30, 790, and 2,400 nM, respectively) and is without effect on other prostanoid receptors; implicates EP4 signaling in immune and autoimmune responses, inflammation, and cancer
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Cayman Chemical Lpd N2-3L 5mg
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An ionizable cationic lipid; has been used in the generation of SMLNPs encapsulating mRNA for use in vitro and in vivo; SMLNPs containing lipid N2-3L and encapsulating a luciferase reporter accumulate at the site of injection and in the draining lymph nodes of mice; lipid N2-3L-containing SMLNPs encapsulating ovalbumin mRNA and R-848 promote dendritic cell maturation and antigen presentation, reduce tumor volume, and increase survival in an MC-38-OVA murine model of colon cancer
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Medchemexpress LLC HY-B2137 100mg Medchemexpress, S-(+)-Ketoprofen CAS:22161-81-5 Purity:>98%
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Medchemexpress, HY-B2137 100mg S-(+)-Ketoprofen CAS:22161-81-5 S-(+)-Ketoprofen is a potent inhibitor of both COX-1 and COX-2 with IC 50 s of 1.9 and 27 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC BMS-986189 | 1629665-96-8 | 99.6% | 1887.21 | 50 MG
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BMS-986189 is a macrocyclic peptide PD-1/PD-L1 interaction with an IC50 of 1.03 nM inhibitor. It can be used for cancer research, such as human lung carcinoma cells L2987.
- Appearance: Solid, white to off-white
- Purity: 99.58%
- Molecular weight: 1887.21
- Solubility in DMSO: ≥ 100 mg/mL
- Solubility in H2O: ≥ 1 mg/mL
- Storage (powder): -80°C for 2 years, -20°C for 1 year
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
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Medchemexpress LLC GNE-235 | 3036574-72-5 | C13H16N4O | 1 ML
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GNE-235 is a compound that selectively targets the second bromodomain of PBRM1, exhibiting a KD of 0.28 ± 0.02 μM. It is utilized for evaluating the cellular function of PBRM1.
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Cayman Chemical ANTIBODY C-176 25mg
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A STING inhibitor; reduces STING-, but not RIG-I or TBK1-, mediated IFN-β reporter activity in HEK293 cells from 0.01-5 μM; reduces serum levels of type-I IFNs and cardiac inflammation the in Trex-/- mouse model of multi-organ inflammation
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Cayman Chemical ANTIBODY AZ 505 10mg
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An inhibitor of SMYD2 (IC50 = 0.12 μM); selective for SMYD2 over SMYD3, DOT1L, EZH2, GLP, G9A, and SET7/9 (IC50s = >83.3 μM); delays cyst growth in EArly- and late-stage Pdk1 conditional knockout mouse models of polycystic kidney disease at 10 mg/kg
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Medchemexpress LLC L-Alanine, N-[(3α,5β)-3-hydroxy-24-oxocholan-24-yl]- | 1428095-28-6 | 97.4% | 447.65 | 25 MG
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L-Alanine, N-[(3α,5β)-3-hydroxy-24-oxocholan-24-yl]- | 1428095-28-6 | 97.4% | 447.65 | 25 MG
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Medchemexpress LLC CID 697851 | 312508-42-2 | C14H12N4OS | 5 MG
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CID 697851 is a solid, light yellow to yellow compound that functions as an AddAB and RecBCD inhibitor. It offers IC50s of 13 and 33 nM, making it suitable for antibacterial research.
- Functions as an AddAB and RecBCD inhibitor
- Offers IC50s of 13 and 33 nM
- Suitable for antibacterial research
- High purity (99.49%)
- Solid appearance
- Color ranges from light yellow to yellow
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Selleck Chemical LLC OPN expression inhibitor 1 E4781-25MG
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OPN Expression Inhibitor 1 (Compound 11) is a DHA ether derivative containing a 1 2 3-triazole ring that effectively inhibits osteopontin (OPN) expression It exhibits significant potential as an anticancer agent by specifically targeting OPN a key factor in breast cancer progression and metastasis
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