Bioactive Small Molecules
Cayman Chemical 3-ethoxy-4-methoxy N,N-Diethylhexedrone (hydrochloride), Purity: ≥98%, 5 mg
An analytical reference standard categorized as a cathinone; intended for research and forensic applications
Medchemexpress LLC DL-homocysteine thiolactone hydrochloride | 6038-19-3 | MFCD00012724 | 100.0% | 153.63 g/mol | C4H8ClNOS | 10 G
DL-homocysteine thiolactone hydrochloride is a cyclic amino acid derivative (hydrochloride salt) used for research applications. It appears as a white to off-white solid, has CAS 6038-19-3 and molecular weight 153.63 g/mol, and is supplied in laboratory pack sizes for analytical and experimental use.
Selleck Chemical LLC TAS4464 S8849-5MG
TAS4464 is a potent and highly selective NEDD8 activating enzyme (NAE) inhibitor with IC50 of 0 955 nM TAS4464 exhibits superior antitumor activity with prolonged target inhibition
Cayman Chemical Acifran, Purity: ≥98%, CAS: 72420-38-3, 10 mg
A niacin receptor agonist; binds to HCA2 (IC50 = 1.12 µM); induces ERK1/2 phosphorylation in CHO-K1 cells expressing HCA2 or HCA3 from 0.01-10 µM; reduces serum triglyceride and LDL levels and increases the ratio of HDL to total cholesterol in hyperlipidemic rats at 1 mg/kg; reduces serum triglyceride levels in a rat model of STZ-induced diabetes
Apexbio Technology LLC CEP-18770, 10mg. Cas: 847499-27-8 MFCD: MFCD18251439. Proteasome inhibitor
CEP-18770 is a novel, potent and reversible P2 threonine boronic acid inhibitor of proteasome that inhibits proteasomes chymotrypsin-like activity, with the value of inhibition constant IC50 of 3.8 nM, by down-modulating the activity of nuclear factor-KB (NF-KB). Other sizes are available. Please inqury us for quote.
Medchemexpress LLC CD63 Human/Cynomolg 5ug
CD63 protein acts as a receptor for TIMP1 activating cell signaling pathways and promoting cell survival It plays a key role in integrin signaling leading to activation of AKT FAK/PTK2 and MAP kinases CD63 Protein Human/Cynomolgus (HEK293 N-His) is the recombinant human-derived CD63 protein expressed by HEK293 with N-6 His labeled tag
Medchemexpress LLC (S)-1-(6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethanamine dihydrochloride | 1980023-97-9 | MFCD32670786 | 98.3% | 279.15 | C10H13Cl2FN4 | 1 G
A chiral dihydrochloride salt used as a drug intermediate in medicinal chemistry research and chemical synthesis.
- A chiral pyridinyl ethanamine used as a synthetic intermediate.
- Appearance: light yellow to yellow solid.
- Purity about 98.3% by assay.
- CAS number 1980023-97-9, molecular formula C10H13Cl2FN4, molecular weight 279.15.
- Available in small lab sizes from 100 mg to 10 g.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Selleck Chemical LLC Flavopiridol HCl 10mg 131740-09-5 NSC 649890 HCl, alvocidib, L86-8275, HMR-1275, DSP-2033
Flavopiridol HCl (NSC 649890 HCl, alvocidib, L86-8275, HMR-1275, DSP-2033) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM in cell-free assays. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Flavopiridol HCl induces autophagy and ER stress. Flavopiridol HCl blocks HIV-1 replication. Phase 1/2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC WIF-1 Human HEK293 250ug
WIF-1 Protein, Human (HEK293, His) is a lyophilized recombinant human Wnt inhibitory factor-1, expressed in HEK293 cells with a C-terminal 6xHis tag. It is intended for research on WNT signaling and is supplied with certificate of analysis-verified purity, low endotoxin, and storage and reconstitution guidance for extended stability.
- Purity ≥95% as determined by reducing SDS-PAGE.
- Low endotoxin level (<1 EU/μg).
- Molecular weight approximately 42-48 kDa.
- Supplied as lyophilized powder for stability.
- Expression system HEK293 supports mammalian post-translational modifications.
- Reconstitute at ≥100 μg/mL and add carrier protein for long-term storage.
Medchemexpress LLC H-Tyr-Tyr-OH 100mg | 1050-28-8 | 100 MG
H-Tyr-Tyr-OH (L-tyrosyl-L-tyrosine) is a dipeptide inhibitor of angiotensin I-converting enzyme (ACE) used in biochemical and hypertension research. It exhibits ACE inhibitory activity (reported IC50 0.028 mg/mL) and is supplied as a high-purity solid or as ready-to-use DMSO solutions suitable for assay preparation.
- High purity: 99.02%.
- Molecular formula C18H20N2O5; molecular weight 344.36 g/mol.
- Available as 100 mg solid and as DMSO solutions for convenient reconstitution.
- Suitable for ACE activity assays and antihypertensive mechanism studies.
Medchemexpress LLC Ro3201195 | 249937-52-8 | 371.36 | C19H18FN3O4 | 100 MG
RO3201195 is a research-grade small-molecule inhibitor of p38 mitogen-activated protein kinase (p38 MAPK). It inhibits WS cell proliferation with a reported IC50 of 190 nM. The compound has molecular formula C19H18FN3O4 and molecular weight 371.36 g·mol⁻¹ and is supplied for in vitro research use.
- Inhibits p38 MAPK with reported cellular IC50 of 190 nM.
- Molecular formula C19H18FN3O4; molecular weight 371.36 g·mol⁻¹.
- Soluble in DMSO (50 mg/mL; may require ultrasonic treatment).
- Powder storage: -20°C (stable for 3 years); in solvent: -80°C for 6 months or -20°C for 1 month.
- Provided in small research pack sizes suitable for laboratory studies.
- Intended for research use only; not for human or clinical use.
Apexbio Technology LLC Cy3 azide , 25mg. Cas: MFCD: MFCD31580114. used for Click chemistry to label alkyne-modified oligonucleotides
Sulfo-Cy3 azide is a sulfonated, hydrophilic and highly water soluble dye for Click Chemistry. For labeling of various molecules in aqueous phase for brightness and photostability of fluorophore, sulfo-Cy3 azide is an ideal choice. Other sizes are available. Please inqury us for quote.
AdipoGen Opaganib
Chemical. CAS 915385-81-8. Formula C23H25ClN2O. MW 380.9. Opaganib is a selective inhibitor of sphingosine kinase 2 SPHK2 Ki = 9.8 μM, a lipid kinase that catalyzes formation of the lipid signaling molecule sphingosine 1-phosphate S1P. S1P promotes cancer growth, and proliferation and pathological inflammation, including TNF-α signaling and other inflammatory cytokine production. By inhibiting the SK2 enzyme, opaganib blocks the synthesis of S1P which regulates fundamental biological processes such as cell proliferation, migration, immune cell trafficking and angiogenesis, and is also involved in immune-modulation and suppression of innate immune responses from T cells. Opaganip has similar potency toward sphingosine kinase SK2 and dihydroceramide desaturase DES1.
AdipoGen Ellagic acid (1 g)
Chemical. CAS: 476-66-4. Formula: C14H6O8. MW: 302.19. Ellagic acid is a polyphenolic antioxidant that is abundant in many fruits, vegetables, plant bark and peels. It has antioxidant, anticancer, neuroprotective, antimutagenic, anti-inflammatory and organ-preserving properties. It alters cytochrome P450 activity and improvea metabolism and clearance of xenobiotics, as well as altera immune function. Selective, ATP-competitive inhibitor of casein kinase 2 (CK2). Ellagic acid also blocks methylation of arginine 17 of histone 3 (H3R17) by coactivator-associated arginine methyltransferase 1 (CARM1) without significantly altering histone acetylase or DNA methyltransferase activity. It acts as a scavenger of oxygen species produced by hydrogen peroxide treatment and as a protector of the DNA double helix from alkylating agent injury. Also reported to inhibit topoisomerases I and II and gyrase and glutathione S-transferase.
Cayman Chemical CUMYL-NBMICA, Purity: ≥98%, 5 mg
An analytical reference standard that is structurally similar to known synthetic cannabinoids; intended for research and forensic applications