Protein Purification
MilliporeSigma™ Calbiochem™ Granzyme B Inhibitor I
The Granzyme B Inhibitor I controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ SHIP2 Inhibitor II, CPDA
A cell-permeable aminopyridine acetamide based compound that acts as an inhibitor of SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2) that can overcome insulin resistance in 3T3-L1 adipocytes.
MilliporeSigma™ Calbiochem™ GW1929
A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays).
MilliporeSigma™ Calbiochem™ Valproic Acid, Sodium Salt
A cell-permeable, short-chained fatty acid that inhibits histone deacetylase (IC50 = 400 μM for HDAC1).
MilliporeSigma™ Calbiochem™ InSolution™ γ-Secretase Inhibitor IX
InSolution™ g-Secretase Inhibitor IX, CAS 208255-80-5, is a 25 mM (5 mg/462 μl or 10 mg/924 μl) solution of g-secretase Inhibitor IX (DAPT; Cat. No. 565770) in DMSO.
MilliporeSigma™ Calbiochem™ Hesperadin
Hesperadin primarily used in Inhibition.
MilliporeSigma™ Calbiochem™ LY 83583
A cell-permeable, competitive inhibitor of soluble guanylate cyclase (IC50 = 2 μM).
MilliporeSigma™ Calbiochem™ AG 1478
A cell-permeable, reversible, ATP-competitive, highly potent and selective inhibitor of epidermal growth factor receptor kinase versus HER2-neu and platelet-derived growth factor receptor kinase.
MilliporeSigma™ Calbiochem™ mTOR Inhibitor XI, Torin1
mTOR Inhibitor XI, Torin1, CAS 1222998-36-8, is a cell-permeable, highly potent, ATP-competitive inhibitor of mTOR and DNA-PK (IC50 = 4.32 and 6.34 nM, respectively).
MilliporeSigma™ Calbiochem™ SIRT1/2/3 pan Inhibitor
A thienopyrimidinylcarboxamide that acts as a highly potent, reversible pan sirtuin (SIRT) inhibitor (IC50 = 15, 10, and 33nM for SIRT1, 2, and 3, respective
MilliporeSigma™ Calbiochem™ Myricetin
A cell-permeable flavanoid that displays anti-inflammatory, anti-diabetic and anti-cancer properties.
MilliporeSigma™ Calbiochem™ sPLA2-IIA Inhibitor I
The sPLA2-IIA Inhibitor I controls the biological activity of sPLA2-IIA. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ Adenylyl Cyclase Type V Inhibitor, NKY80
The Adenylyl Cyclase Type V Inhibitor, NKY80, also referenced under CAS 299442-43-6, controls the biological activity of Adenylyl Cyclase Type V.
MilliporeSigma™ Calbiochem™ Colcemid
Cell synchronization agent.
MilliporeSigma™ Calbiochem™ Retro-2
A cell-permeable tricyclic imine compound that inhibits the endosome-to-Golgi retrograde transport, but not cellular uptake, of CtxB, StxB without affecting cellular uptake/trafficking of Tf or EGF.