Protease Inhibitors and Phosphatase Inhibitors
Abcam Puromycin dihydrochloride, Protein biosynthesis inhibitor, 25MG
MW 544.4 Da, Purity >98%. Aminonuclease antibiotic agent. Protein biosynthesis inhibitor. Induces cell cycle arrest in G2/M phase and apoptosis. Inhibits transport of proteins into mitochondria. Inhibits translation in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Puromycin dihydrochloride, Protein biosynthesis inhibitor, 250MG
MW 544.4 Da, Purity >98%. Aminonuclease antibiotic agent. Protein biosynthesis inhibitor. Induces cell cycle arrest in G2/M phase and apoptosis. Inhibits transport of proteins into mitochondria. Inhibits translation in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam HNHA, HDAC inhibitor, 25MG
MW 303.4 Da, Purity >98%. Potent, cell-permeable HDAC inhibitor (IC₅₀ = 100 nM). Induces histone hyperacetylation and p21 transcription with concomitant inhibition of cell cycle progression. Arrests cell cycle at G₁/S phase in cancer cells. Antitumor and antiangiogenic agent. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
![Medchemexpress LLC (2R)-2-(3-{[4-(2-amino-2-methylpropyl)phenyl]sulfonyl}propyl)-2-(2,4-difluorophenyl)cyclopropane-1,1 | 1137916-97-2 | 99.3% | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000299012.png-250.jpg)
Medchemexpress LLC (2R)-2-(3-{[4-(2-amino-2-methylpropyl)phenyl]sulfonyl}propyl)-2-(2,4-difluorophenyl)cyclopropane-1,1 | 1137916-97-2 | 99.3% | 10 MG
MK-0941 is an orally active, allosteric glucokinase activator supplied for preclinical research into glucose regulation and type 2 diabetes. It increases insulin secretion and glucose uptake and is used in in vitro enzyme assays and in vivo pharmacology studies to evaluate glucokinase modulation.
- Orally active, allosteric glucokinase activator for mechanism studies.
- High reported purity suitable for analytical and biological assays.
- Available in small milligram quantities for preclinical work.
- Offered as solid and as DMSO solution formats for flexible dosing.
- Storage guidance included for solid and solvent preparations.
- Structural and chemical identifiers provided for reproducibility.
Abcam MMP3 Inhibitor Screening Assay Kit (Colorimetric).
MMP3 Inhibitor Screening Assay Kit (Colorimetric).
The product is subject to the following: Abcam Restricted Use Statement
Abcam P4HB Inhibitor Screening Assay Kit.
P4HB Inhibitor Screening Assay Kit.
The product is subject to the following: Abcam Restricted Use Statement
Abcam PQ 401, Cell-permeable IGF1R inhibitor, 50MG
MW 341.8 Da, Purity >99%. Cell-permeable IGF1R inhibitor (IC₅₀ = 12 μM for IGF-stimulated autophosphorylation). Shows antiproliferative effects against MCF-7 breast cancer cells. Induces renal hypertrophy in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam PQ 401, Cell-permeable IGF1R inhibitor, 10MG
MW 341.8 Da, Purity >99%. Cell-permeable IGF1R inhibitor (IC₅₀ = 12 μM for IGF-stimulated autophosphorylation). Shows antiproliferative effects against MCF-7 breast cancer cells. Induces renal hypertrophy in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC PM-81I | 1637532-83-2 | 99.9% | 845.91 | 1 MG
PM-81I is a potent STAT6 inhibitor that targets the SH2 structural domain, effectively reducing STAT6 phosphorylation levels. This compound is valuable for studies in areas such as allergic lung disease, allergic rhinitis, chronic obstructive pulmonary disease, and cancer. It is supplied as a white to off-white solid with high purity.
- Potent STAT6 inhibitor
- Targets SH2 structural domain
- Reduces STAT6 phosphorylation levels
- Useful for allergic lung disease research
- Useful for allergic rhinitis research
- Useful for chronic obstructive pulmonary disease research
- Useful for cancer research
- White to off-white solid appearance
- High purity
Sigma Aldrich Fine Chemicals Biosciences Diethylenetriaminepentaacetic acid >=98% (titration) | 67-43-6 | MFCD00004289 | 500G
Diethylenetriaminepentaacetic acid >=98% (titration) | Purity: >=98% (titration) | Mol Wt: 393.35 | 67-43-6 | MFCD00004289 | 500G
Apexbio Technology LLC GSK2606414, 50mg Cas No: 1337531-36-8 MFCD: MFCD25976926
GSK2606414 is a selective inhibitor of PERK with IC50 value of 0.4nM.[1]PERK (PRKR-like endoplasmic reticulum kinase or protein kinase R (PKR)-like endoplasmic reticulum kinase) is also known as EIF2AK3 (Eukaryotic translation initiation factor 2-alpha kinase 3). There are other sizes available. Please inqury us for quote.
Abcam C16, PKR inhibitor, 25MG
MW 268.3 Da, Purity >98%. Specific double-stranded RNA-dependent protein kinase (PKR) inhibitor. Prevents PKR-induced neuronal loss in vivo. Inhibits apoptotic PKR/eIF2α signaling pathway in vivo. Neuroprotective, antitumor and anti-inflammatory agent. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Enalaprilat, Angiotensin II converting enzyme inhibitor, 250MG
MW 384.4 Da, Purity >99%. Angiotensin II converting enzyme inhibitor. Inhibits angiotensin II-induced cardiac fibroblast proliferation. Active metabolite of Enalapril (ab141929). Antihypertensive agent. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Echelon Biosciences Research Labs BODIPY TMR Phosphatidylinositol 100 ug
BODIPY TMR Phosphatidylinositol is a water soluble analog of Phosphatidylinositol (PI) labeled with the orange fluorophore, Bodipy-TMR, at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol (PI or PtdIns) is biosynthesized from CDP-diacylglycerol and inositol by phosphatidylinositol synthase. PI is the building block for phosphoinositide polyphosphates through phosphorylation by PI-kinases and is a substrate for PI-PLC yielding diacylgelycerol. This item is non returnable
Medchemexpress LLC PF-00835231 | 870153-29-0 | 99.3% | 472.53 | 100 MG
PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM for SARS CoV-2 and 4 nM for SARS CoV-1 3CLpro. It is developed for the research of anti-SARS-CoV-2/COVID-19 and can inhibit cell infections as well as suppress infections in animal models.
- Acts as a CoV-2 cysteine 3C-like protease inhibitor.
- Shows potent inhibition against SARS CoV-2 and SARS CoV-1 3CLpro.
- Developed for research in anti-SARS-CoV-2/COVID-19.
- Capable of inhibiting cell infections.
- Demonstrates suppression of infections in animal models.
- Effectively inhibits SARS-CoV-2 USA-WA1/2020.
- Inhibits rhinovirus HRV3C protease.
- Reduces multifocal lung lesions and lung viral load in SARS-CoV-MA15 infected mouse models.