Cell Line Lysates
Cayman Chemical Enniatin A, Purity: ≥99%, CAS: 2503-13-1, 2.5 mg
One of four major analogs in the enniatin complex that has been shown to moderately inhibit ACAT activity in rat liver microsomes (IC50 = 22 µM); demonstrates anthelmintic properties against N. brasiliensis, T. spiralis, and H. spumosa
Cayman Chemical S-(5'-Adenosyl)-L-methionine chloride (hydrochloride), Purity: ≥95%, CAS: 86867-01-8, 2.5 mg
A ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases
Cayman Chemical Amidepsine D, Purity: ≥95%, CAS: 79786-34-8, 2.5 mg
A fungal metabolite that inhibits DGAT activity, preventing triacylglycerol formation (IC50s = 17.5 and 2.8 µM in rat liver microsomes and Raji cells, respectively)
Abcam Ferulic acid methyl ester, Antio x idant agent, 1G
MW 208.21 Da, Purity >99%. Antioxidant agent. Ferulic acid (ab141932) derivative. Putative chemotherapeutic agent. Shows antithrombotic effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Antimycin A1, Purity: ≥98%, CAS: 642-15-9, 2.5 mg
An active component of the antimycin A complex; inhibits electron transport; induces the synthesis of carotenoids in M. marinum at 3.3-160 µM; inhibits ATP-citrate lyase (Ki = 29.5 µM)
Sino Biological Recombinant Human Desmoglein-2 Protein (His Tag), HPLC-verified
A DNA sequence encoding the Human DSG2 (Q14126) (Ala50-Gly609) was expressed with a polyhistidine tag at the C-terminus.
Cayman Chemical Avermectin B1b, Purity: ≥85%, CAS: 65195-56-4, 2.5 mg
A minor component of avermectin broth, used broadly against nematodes, ticks, flies, and ants
Abcam Furafylline, PDE inhibitor, 5MG
MW 260.25 Da, Purity >98%. PDE inhibitor. Selective cytochrome P450IA2 inhibitor (IC₅₀ = 2.4 μM). Methyl xanthine derivative. Shows an expanded duration of action compared to theophylline (ab142599) in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Ikarugamycin, Purity: ≥85%, CAS: 36531-78-9, 2.5 mg
A macrocyclic antibiotic that exhibits cytotoxic effects in cancer cell lines, inhibiting cell proliferation (IC50 = 221.3 nM in HL-60 cells); 1-4 μM inhibits oxidized LDL-induced accumulation of cholesteryl esters in macrophages; inhibits clathrin-coated pit-mediated endocytosis
Sino Biological Recombinant Human CD98 Protein (FITC conjugated, His Tag)
A DNA sequence encoding the Human SLC3A2 (P08195) (Arg206-Ala630) was expressed, with a polyhistidine tag at the N-terminus.
Cayman Chemical Mutant IDH1-IN-1, Purity: ≥98%, CAS: 1355326-21-4, 50 mg
An inhibitor of mutant IDH1 (IC50s = 42, 4, and 80 nM for IDH1R132H/R132H, IDH1R132C/R132C, and IDH1R132H/WT, respectively, for conversion of α-KG to 2-HG); selective for IDH1 mutant conversion of α-KG to 2-HT over IDH1WT/WT conversion of isocitrate to α-KG (IC50 = 1,998 nM) and over IDH2 (IC50s = >10,000 nM); inhibits 2-HG production in vitro (IC50 = 81.5 nM)
Cayman Chemical E6 BerbamIn 10mg
A calmodulin inhibitor that disrupts the activity of calmodulin-dependent enzymes such as myosin light chain kinase (IC50 = 8 µM) and phosphodiesterase 1A (IC50 = 0.53 µM); inhibits P-glycoprotein activity in purified primary cultured rat brain microvessel endothelial cells at 10 µM
Cayman Chemical JMJD2A tudor domaInshumn100ug
Source: Expressed in E. coli • Amino acids: AA: 888-1,023 (N-terminal truncation) • MW: 42.2 kDa
Cell Biolabs Inc 293AAV Cell Line for AAV Packaging
Cell Biolabs' 293AAV Cell Line is a permanent line established from primary embryonic human kidney transformed with human adenovirus type 5 DNA. The genes encoded by the E1 region of adenovirus (E1a and E1b) are expressed in these cells and participate in transactivation of viral promoters, allowing these cells to produce high levels of protein. The 293AAV Cell Line is derived from the parental 293 cells but selected for attributes that increase AAV production. It offers several advantages over the regular 293 cells: (1) Larger cell surface area resulting higher transfection and better yield of AAV; (2) Flattened morphology; and (3) Firm attachment to culture plates, ideal for large scale culture and AAV production.
Cayman Chemical Pyridomycin, Purity: ≥95%, CAS: 18791-21-4, 2.5 mg
A structurally unusual antibiotic that inhibits NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis, including isoniazid-resistant strains (MICs = 0.31-0.63 µg/ml)