Isotopically Labeled Compounds
Medchemexpress LLC Propamocarb-d7 | 1398065-89-8 | 5 MG
Propamocarb-d7 is the deuterium-labeled version of Propamocarb, a systemic fungicide used to protect plants such as cucumbers and tomatoes from pathogens.
- Can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules for quantitation during drug development.
- Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Veratrole-d2 | 203645-56-1 | 99.7% | 50 MG
Veratrole-d2 is a deuterium-labeled form of Veratrole (1,2-Dimethoxybenzene), a compound naturally found in plants that attracts pollinators. Its release exhibits a circadian rhythm, playing an important role in plant reproduction, species differentiation, and interactions with pollinators. This compound can also be demethylated by cytochrome P-450 in *Streptomyces setonii*. Deuterated compounds like Veratrole-d2 are utilized as tracers for quantification during drug development due to their potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Deuterium-labeled version of Veratrole
- Key compound in plant reproduction and interactions with pollinators
- Can be demethylated by cytochrome P-450
- Used as a tracer for quantification in drug development
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Revvity Health Sciences Inc Sulfur-35 Radionuclide, 10mCi (370MBq), Specific Activity: 250-1000mCi (9.25-37.0GBq)/mmol
Sulfur-35 Radionuclide, 10mCi (370MBq), Specific Activity: 250-1000mCi (9.25-37.0GBq)/mmol
Medchemexpress LLC DEHP-d4 (Bis(2-ethylhexyl) phthalate-d4) | 93951-87-2 | MFCD00143759 | 99.9% | 1 ML
DEHP-d4 is a deuterium-labeled variant of Bis(2-ethylhexyl) phthalate (DEHP), an endogenous metabolite. This compound is intended for research purposes, specifically as a tracer or an internal standard for quantitative analysis through methods such as NMR, GC-MS, or LC-MS. Deuterium substitution in drug molecules has been noted for its potential to alter pharmacokinetic and metabolic profiles.
Features and Benefits:
- Used as a tracer.
- Serves as an internal standard for quantitative analysis.
- Applicable in NMR, GC-MS, or LC-MS analysis.
- Deuterium labeling can impact pharmacokinetic and metabolic profiles.
- High purity of 99.9%.
![Medchemexpress LLC Ethanesulfonic acid, 2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl-2,2,4,4-d4]amino]- | 252030-90-3 | 99.5% | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000412729-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Ethanesulfonic acid, 2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl-2,2,4,4-d4]amino]- | 252030-90-3 | 99.5% | 5 MG
Taurocholic acid-d4 is a deuterium-labeled form of Taurocholic acid, which is a bile acid crucial for the emulsification of fats. This product can be utilized as a tracer in various applications or as an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes incorporated into drug molecules
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Taurocholic acid-d4 | 252030-90-3 | 99.5% | 100 UG
Taurocholic acid-d4 is deuterium labeled Taurocholic acid, a bile acid involved in the emulsification of fats. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeled for use as a tracer
- Involved in fat emulsification
- Suitable for quantitative analysis
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Sodium propionate-d3 | 1210410-35-7 | 98.4% | 100 MG
Sodium propionate-d3 is the deuterium labeled Propionate sodium (HY-B1773A). Sodium propionate is an orally active short-chain fatty acid produced by intestinal bacteria from the metabolism of dietary fiber. It increases PPAR-γ, inhibits NF-κB activation, reduces COX-2 expression and NO production, and induces Apoptosis and Autophagy. Sodium propionate reduces HSV-1-induced keratitis and has anticancer effects against glioblastoma. It also exhibits neuroprotective, antioxidant, and anti-inflammatory activities, and can be used in the research of spinal cord injury and Alzheimer's disease.
- Can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes incorporated into drug molecules for quantitation during drug development.
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC HEPES-d18 | 203805-87-2 | 99.9% | 25 MG
HEPES-d18 is the deuterium labeled HEPES. It is a nonvolatile zwitterionic chemical buffering agent widely used in cell culture, effective at pH 6.8 to 8.2, and also a potent inducer of lysosome biogenesis. This compound can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has the potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Dimetridazole-d3 (1,2-Dimethyl-5-nitroimidazole-d3) | 64678-69-9 | 99.8% | 1 MG
Dimetridazole-d3 (1,2-Dimethyl-5-nitroimidazole-d3) is a deuterium-labeled version of Dimetridazole, a nitroimidazole antibiotic that inhibits protein synthesis in Campylobacter jejuni cultures and has genotoxic properties. This compound is suitable for research on protozoal and bacterial infections.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Puromycin-d3 dihydrochloride | 1 MG
Puromycin-d3 dihydrochloride is a deuterium-labeled aminonucleoside antibiotic that inhibits protein synthesis. Stable heavy isotopes have been incorporated into this drug molecule for use as a tracer in drug development. Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
- Inhibits protein synthesis.
- Deuterium labeled compound.
- Functions as a tracer for quantitation in drug development.
- Affects pharmacokinetic and metabolic profiles.
- Molecular formula: C₂₂H₂₈D₃Cl₂N₇O₅
- Molecular weight: 547.45 g/mol
- Targets bacterial, antibiotic, and isotope-labeled compounds.
- Soluble in methanol, DMSO, and ethanol.
Medchemexpress LLC Nortriptyline hydrochloride | 894-71-3 | 99.98% | 1 G
Nortriptyline (Desmethylamitriptyline) hydrochloride is the main active metabolite of Amitriptyline and acts as a tricyclic antidepressant. It is also a potent autophagy inhibitor and has anticancer effects.
- Main active metabolite of Amitriptyline
- Tricyclic antidepressant
- Potent autophagy inhibitor
- Has anticancer effects
Medchemexpress LLC Isoproturon-d3 | 352438-80-3 | 99.8% | 1 MG
Isoproturon-d3 is the deuterium labeled Isoproturon. Isoproturon belongs to the phenylurea herbicide family and is a systemic and selective herbicide. It is widely applied for killing weeds in farmland, specifically annual grasses and broad-leaved weeds in spring and winter wheat, winter rye, and spring and winter barley. This product is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cambridge Isotope Laboratories N,n-dimethylformamide-d7 (d, 99.5%), 4472-41-7, MFCD00003286, 10 g
Chemical Formula: (CD3)2NCDO, MW: 80.14, 99.5%, Synonyms: DMF-d7, Heptadeutero-N,N-dimethylformamide, Dimethyl formamide, N-Formyldimethylamine.
Cayman Chemical StearIc AcId-d4 100mg
An internal standard for the quantification of stearicacid by GC- or LC-MS
Revvity Health Sciences Inc 3H Extended Range Quenched Standards, 7 mL Vial
3H Extended Range Quenched Standards, 7 mL Vial