Isotopically Labeled Compounds
Medchemexpress LLC D-Glucose-13C-3 | 105931-74-6 | 99.7% | 50 MG
D-Glucose-13C-3 | 105931-74-6 | 99.7% | 50 MG
Medchemexpress LLC Adenosine-1′-13C | 201996-55-6 | 96.3% | 5 MG
Adenosine-1′-13C is the 13C labeled Adenosine. Adenosine (Adenine riboside) is a ubiquitous endogenous autacoid that acts through four G protein-coupled receptors: A1, A2A, A2B, and A3. It affects almost all aspects of cellular physiology.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Cinnamic acid-13C3 (3-Phenylacrylic acid-13C3) | 2734410-01-4 | 151.14 | 1 MG
Cinnamic acid-13C3 (3-Phenylacrylic acid-13C3) is a 13C labeled Cinnamic acid, with potential use in cancer intervention. It has shown IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate, and lung carcinoma cells.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules as tracers for quantitation during drug development.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
Cambridge Isotope Laboratories 2-Chloronaphthalene (D7 98%) 100 ug/mL in nonane 1 2 mL
2-Chloronaphthalene (D7 98%) 100 ug/mL in nonane 1 2 mL
Medchemexpress LLC Glycidyl oleate-d5 | 1426395-63-2 | C21H33D5O3 | 5 MG
Glycidyl oleate-d5 is a deuterium labeled form of Glycidyl oleate. This compound incorporates stable heavy isotopes of hydrogen, carbon, and other elements, making it suitable for use as a tracer and internal standard in quantitative analysis. Deuteration has shown potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes for quantitation during drug development.
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Sebutylazine-dd5 (ethyl-dd5) | 1219805-56-7 | C9H11D5ClN5 | 5 MG
Sebutylazine-dd5 (ethyl-dd5) is a deuterium labeled chemical intended for research use only. This compound serves as a tracer and an internal standard for quantitative analysis through techniques such as NMR, GC-MS, or LC-MS. Its deuterium labeling can impact pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- For research use only
Medchemexpress LLC 6PPD-quinone-d5 | 2750119-14-1 | C18H17D5N2O2 | 5 MG
6PPD-quinone-d5 is a deuterium-labeled compound, specifically the deuterium-labeled form of 6PPD-quinone. It is utilized in drug development as a tracer and internal standard for quantitative analysis, primarily due to deuterium substitution's potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Tecovirimat-d4 | 869572-92-9 | 98.95% | 380.35 | 5 MG
Tecovirimat-d4 is a deuterium-labelled Tecovirimat (HY-14805), an orally bioavailable and selective compound effective against orthopoxviruses including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox, and variola viruses. It targets the orthopoxvirus protein VP37, which is essential for membrane envelopment of intracellular mature virus particles.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Cariprazine-d8 | 1308278-50-3 | 98.8% | 435.46 | 1 MG
Cariprazine-d8 is a deuterium labeled Cariprazine, a novel antipsychotic agent candidate exhibiting high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Retinoic acid-d6 | 2483831-72-5 | 98.9% | 306.47 | 1 MG
Retinoic acid-d6 is the deuterium labeled Retinoic acid, a metabolite of vitamin A crucial for cell growth, differentiation, and organogenesis. It acts as a natural agonist of RAR nuclear receptors (IC50s of 14 nM for RARα/β/γ) and binds to PPARβ/δ with a Kd of 17 nM. This compound inhibits transcription factor Nrf2 through activation of retinoic acid receptor alpha.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Azilsartan-d5 (TAK-536-d5) | 1346599-45-8 | 99.4% | 461.48 | 1 ML
Azilsartan-d5 is the deuterium-labeled Azilsartan (TAK-536), a specific and potent angiotensin II type 1 receptor antagonist. This compound can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium-labeled Azilsartan
- Specific and potent angiotensin II type 1 receptor antagonist
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Retinoic acid-d5 | 78996-15-3 | 99.07% | 305.47 | 1 MG
Retinoic acid-d5 is the deuterium labeled Retinoic acid. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid binds to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Omadacycline-d9 (PTK 0796-d9; Amadacycline-d9) | 2272886-41-4 | 99.2% | 565.71 | 1 MG
Omadacycline-d9 (PTK 0796-d9; Amadacycline-d9) is the deuterium labeled Omadacycline that can be used as the internal standard for the analysis of Omadacycline. This product is for research use only.
- Deuterium labeled compound
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Posaconazole-d5 | 1217785-83-5 | 99.1% | 705.81 | 1 MG
Posaconazole-d5 is a deuterium-labeled form of Posaconazole, a broad-spectrum triazole compound with antifungal activity. This compound is suitable for various quantitative analyses and as a tracer in research applications.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Broad-spectrum antifungal activity
Medchemexpress LLC L-Xylose-2-13C | 478506-63-7 | 99.0% | C413CH10O5 | 1 MG
L-Xylose-2-13C is the 13C labeled L-Xylose. L-Xylose is a rare sugar and the levorotatory form of Xylose. This compound serves as a raw material for the synthesis of various drugs and bioactive molecules. It is intended for research use only.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.