Isotopically Labeled Compounds
Medchemexpress LLC Ercalcidiol-d3 | 1217467-39-4 | 99.9% | 415.67 | 100 UG
Ercalcidiol-d3 is the deuterium labeled Ercalcidiol, a metabolite of Vitamins D2. It serves as an indicator of vitamin D status and can be utilized as a tracer and internal standard for quantitative analysis methods such as NMR, GC-MS, or LC-MS. Stable heavy isotopes, including hydrogen and carbon, are incorporated into this drug molecule. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as an indicator of vitamin D status.
- Functions as a tracer in quantitative analysis.
- Serves as an internal standard for NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes.
- Potential to affect pharmacokinetic and metabolic profiles of drugs.
Cambridge Isotope Laboratories GLYCODEOXYCHOLIC ACID (2,2,4,4-D4, 98%), 10 MG, 1069132-37-1
GLYCODEOXYCHOLIC ACID (2,2,4,4-D4, 98%), 10 MG, 1069132-37-1
Medchemexpress LLC 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl-4,4,6,6,6-d5)- | 1185995-18-9 | 99.9% | 5 MG
1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl-4,4,6,6,6-d5)- | 1185995-18-9 | 99.9% | 5 MG
Medchemexpress LLC L-Valine-2,3,4,4,4,4′,4′,4′-d8, N-[(1,1-dimethylethoxy)carbonyl]- | 153568-33-3 | 225.31 | 25 MG
Boc-L-Valine-d8 is the deuterium labeled Boc-L-Valine. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements like this have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC (S)-(+)-Ibuprofen-d3 | 1329643-44-8 | MFCD30748182 | 100.0% | 209.30 g/mol | C13H15D3O2 | 10 MG
(S)-(+)-Ibuprofen-d3 is the S-enantiomer of ibuprofen labeled with three deuterium atoms, supplied as a solid analytical standard for use in analytical, pharmacokinetic, and tracer studies. It is provided as a high-purity, stable powder intended for research applications only.
- High isotopic labeling suitable for use as an internal standard.
- High purity (reported 99.96%) for analytical accuracy.
- White to off-white solid form for easy handling and storage.
- Stable under recommended storage conditions (powder: -20°C).
- Available in small quantity sizes for analytical workflows.
Medchemexpress LLC Lidocaine-d10 hydrochloride | 1189959-13-4 | 99.6% | 5 MG
Lidocaine-d10 hydrochloride is the deuterium-labeled Lidocaine hydrochloride. It inhibits sodium channels involving complex voltage and use dependence, and decreases the growth, migration, and invasion of gastric carcinoma cells by up-regulating miR-145 expression and inactivating MEK/ERK and NF-κB signaling pathways. This amide derivative has potential for research into ventricular arrhythmia and is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Moxidectin-d3 | 113507-06-5 | 95.2% | 1 MG
Moxidectin-d3 (CL-301423-d3) is a deuterium-labeled version of Moxidectin. Moxidectin is an orally active macrolide (ML) anthelmintic used for the prevention and control of heartworms and roundworms. It is also a substrate of BCRP and P-glycoprotein (P-gp) in vivo, and is secreted into breast milk and effluxed from the host and parasite by Bcrp1 and P-gp.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules.
- Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC L-alanine-13C3, 15N | 202407-38-3 | MFCD19443802 | 98.0% | 93.06 g·mol⁻1 | 13C3H7 15NO2 | 10 MG
L-alanine-13C3,15N is an isotopically labeled form of the amino acid L-alanine in which three carbon atoms are 13C and the nitrogen is 15N. Supplied as a 10 mg vial for research use, it serves as a stable isotope internal standard, tracer, or reference material for analytical and biochemical workflows. Purity is 98.0% and molecular weight is 93.06 g·mol⁻1.
- Isotopically labeled standard for mass spectrometry and metabolomics.
- Supplied in a small, research-scale package suitable for analytical assays.
- High purity suitable for quantitative internal standard applications.
- Stable, non-radioactive tracer for metabolic and pathway studies.
- Provided with batch-specific datasheet and certificate of analysis for traceability.
Apexbio Technology LLC Deoxycholic acid 83-44-3 10mM (in 1mL DMSO)
Deoxycholic acid (CAS 83-44-3) is a secondary bile acid derived from cholic acid commonly extracted from animal bile sources such as pig bile It acts as a natural surfactant involved in the emulsification and absorption of dietary fats in the intestine by disrupting lipid membranes and facilitating micelle formation Owing to its amphipathic properties deoxycholic acid is widely utilized in studies investigating lipid metabolism cell membrane dynamics and bile acid signaling pathways The compound is soluble in ethanol ether methanol acetone acetic acid and alkaline solutions and is typically stored in a sealed cool and dry environment to maintain stability
Medchemexpress LLC Tetracosane-d50 | 16416-32-3 | 25 MG
Tetracosane-d50 is a deuterium-labeled form of Tetracosane. It is intended for research use only and can serve as a tracer or an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS. Deuterium substitution has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer for quantitation during drug development
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration can influence pharmacokinetic and metabolic profiles of drugs
- Suitable for research purposes only
Medchemexpress LLC Maprotiline-d3 (hydrochloride) | 1329496-63-0 | MFCD32672112 | 98.8% | 316.88 | C20H21D3ClN | 10 MG
Maprotiline-d3 (hydrochloride) is the deuterium-labeled analogue of maprotiline hydrochloride provided for research use as a stable isotope reference or tracer in analytical assays. It is supplied as a powder for method development and quantitative LC-MS/GC-MS workflows; not for human use. Follow the product datasheet and SDS for handling and storage.
Medchemexpress LLC Lidocaine-d6 hydrochloride | 2517378-96-8 | >95% | 1 MG
Lidocaine-d6 hydrochloride is a deuterium-labeled form of Lidocaine hydrochloride, primarily used in research. This compound acts as a sodium channel inhibitor and has shown potential in reducing the growth, migration, and invasion of gastric carcinoma cells by up-regulating miR-145 expression and inactivating MEK/ERK and NF-κB signaling pathways. It is also recognized as an effective agent for treating ventricular arrhythmia.
- Used as a tracer for research applications
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Inhibits sodium channels
- Decreases growth, migration, and invasion of gastric carcinoma cells
- Acts as an agent to treat ventricular arrhythmia
Medchemexpress LLC Glyphosate-d2-1 | 1071-83-6 | MFCD00055350 | 99.9% | 171.09 | C3H6D2NO5P | 10 MG
Glyphosate-d2-1 is a deuterium-labeled analytical standard of glyphosate supplied in milligram quantities for use in analytical and research applications. It is intended as an isotopically labeled internal standard to improve quantitation and identification in mass spectrometry and other analytical methods.
- Deuterium-labeled glyphosate for use as an internal standard.
- Supplied in milligram-scale quantity suitable for analytical workflows.
- High listed purity for trace-level quantitation.
- Accompanied by datasheet, certificate of analysis, and spectral reports.
- Suitable for LC-MS/MS method development and validation.
Cayman Chemical DeoxycholIc AcId 10g
A secondary bile acid; inhibits TCA-induced spore germination in seven C. difficile strains at 0.2% v/v; inhibits growth and decreases the cytotoxicity of C. difficile culture supernatants to Vero cells at 0.02% v/v; inhibits ionizing radiation-induced p53-dependent transcription in a reporter assay using HCT116 cells at 200 µM; fecal and intestinal tissue levels are increased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet; increased serum levels have been found in patients with colorectal cancer
Medchemexpress LLC Dotriacontane-d66 | 62369-68-0 | 99.09% | 517.27 | 50 MG
Dotriacontane-d66 is the deuterium labeled Dotriacontane. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS