Carbohydrates
Medchemexpress LLC D-Glucuronic acid (Standard) | 6556-12-3 | 100 MG
D-Glucuronic acid (Standard) is an analytical standard intended for research and analytical applications. It is a significant component of numerous anti-inflammatory proteoglycans, contributing to embryonic development and inhibiting cell aggregation. When metabolized into ethyl glucuronide, it activates Toll-like receptor 4 (TLR4), which is associated with pain. Furthermore, D-Glucuronic acid and its derivative, glucurono-lactone, are known as liver detoxifiers and its derivatives also exhibit anti-tumor activity.
- Analytical standard for assays
- Intended for research and analytical use
- Utilized in HPLC, GC, and MS research experiments
- Major component of anti-inflammatory proteoglycans
- Promotes embryonic development
- Inhibits cell aggregation
- Acts as a liver detoxifier
- Derivatives possess anti-tumor activity
- Solid, white to off-white appearance
- Purity of 99.93%
Medchemexpress LLC Bet-in-19 (compound 146) | 1643947-30-1 | 99.7% | 333.39 g/mol | C19H19N5O | 10MM 1ML
BET-IN-19 is a small-molecule inhibitor of BET family bromodomains used in epigenetic and oncology research. It inhibits tetra-acetylated histone H4 binding to BRD4 bromodomain 1 and has demonstrated cellular activity in reported assays (IC50 ≤0.3 μM). Supplied as a powder for laboratory research.
- Small-molecule BET bromodomain inhibitor for epigenetic and oncology research.
- Demonstrated cellular activity with IC50 ≤0.3 μM in reported assays.
- High purity (99.74%) suitable for in vitro studies.
- Molecular formula C19H19N5O, molecular weight 333.39 g/mol.
- Supplied as a powder; storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- Soluble in DMSO at 100 mg/mL (≈299.95 mM); ultrasonic assistance may be required for dissolution.
Medchemexpress LLC Heparin sodium salt (MW 15kDa) | 9041-08-1 | 15000 (Average) | 5 G
Heparin sodium salt (MW 15kDa) is a polymer of Heparin with a molecular weight of 15kDa. It functions as an anticoagulant by reversibly binding to antithrombin III (ATIII), which significantly increases the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa. This product has shown angiogenic response in late Chorioallantoic Membrane (CAM) assay. It is suitable for laboratory centrifugation and storage.
- Acts as an anticoagulant
- Binds reversibly to antithrombin III (ATIII)
- Accelerates inactivation of coagulation enzymes
- Used in various biological activities targeting thrombin and factor Xa
- Shows angiogenic response in CAM assay
Medchemexpress LLC Heparin | 9005-49-6 | 250 MG
Heparin is a highly sulfated glycosaminoglycan that is widely used as an injectable anticoagulant. It possesses the highest negative charge density of any known biological molecule and significantly inhibits exosome-cell interactions.
- Widely used as an injectable anticoagulant.
- Has the highest negative charge density of any known biological molecule.
- Significantly inhibits interactions between exosomes and cells.
- Intended for research purposes.
Apexbio Technology LLC Amyloid β-Protein (1-15) 183745-81-5 25mg
Amyloid -Protein (1-15) (CAS 183745-81-5) is a synthetic peptide fragment corresponding to the amino-terminal residues 1 15 of the amyloid -protein Amyloid -protein (A ) is derived from the amyloid precursor protein (APP) and is a major constituent of amyloid plaques observed in the brains of Alzheimer s disease (AD) patients A peptides aggregate extracellularly disrupting synaptic function and neuronal communication The 1 15 fragment is widely used in studies investigating the molecular mechanisms of A aggregation toxicity antibody binding and its potential role in neurodegenerative pathogenesis This fragment serves as a valuable tool for exploring therapeutic strategies targeting A -driven pathology in AD research
Medchemexpress LLC D-NMAPPD ((1R,2R)-B13) | 35922-06-6 | MFCD08062172 | 99.7% | 422.56 | C23H38N2O5 | 10MG
D-NMAPPD ((1R,2R)-B13) is a research-grade small molecule inhibitor of acid ceramidase. It modulates NMDA receptor properties by enhancing endogenous ceramide production and has demonstrated anticancer activity in cellular studies. For research use only; not for human or veterinary use.
- Acid ceramidase inhibitor that induces apoptosis in cell models.
- Modulates NMDA receptor function via increased ceramide production.
- CAS number: 35922-06-6.
- Molecular formula: C23H38N2O5; molecular weight: 422.56.
- High purity suitable for research: 99.7%.
- Available in solid and solution formats, including 10 MG and 10 mM in DMSO solutions.
Medchemexpress LLC Integrin alpha V beta 8 protein, mouse (HEK293, His) | >95.0% | 50UG
Recombinant mouse integrin αVβ8 expressed in HEK293 cells with a His tag, provided as a purified heterodimer for research use. The protein is intended for biochemical assays, receptor-ligand interaction studies, and cell adhesion experiments; handle and store according to the supplier datasheet and SDS.
- Recombinant heterodimeric integrin αVβ8 from mouse source.
- HEK293 expression system preserves mammalian post-translational modifications.
- His tag facilitates purification and detection.
- Purity greater than 95% by reducing SDS-PAGE.
- Molecular weight range 80-140 kDa reflecting α and β subunits.
- Supplied in microgram quantities suitable for in-vitro research.
- Datasheet, SDS, and COA provided for batch-specific details.
Medchemexpress LLC Interferon alpha/beta receptor 1 Antibody (YA3833) | Predicted band size: 64 kDa; Observed band size: 110-130 kDa | 100 UL
The Interferon alpha/beta receptor 1 Antibody (YA3833) is a mouse-derived, non-conjugated IgG1 monoclonal antibody designed to target Interferon alpha/beta receptor 1. It is supplied in PBS with 0.05% sodium azide and is affinity purified. This product is intended for research use only, supporting studies related to type I interferon signaling pathways.
- Mouse host
- Monoclonal antibody
- Reactive with human and mouse species
- Affinity purified
- Non-conjugated
- Isotype IgG1
- Supplied as a liquid in PBS with 0.05% sodium azide
- Stable for 1 year when stored at -20°C
- Compatible with Western Blot, Immunohistochemistry-Paraffin, Flow Cytometry, and ELISA applications
Medchemexpress LLC UDP-glucuronic acid (trisodium) | 63700-19-6 | 1 ML
UDP-glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates found across various biological kingdoms. These glycoconjugates include mammalian glycosaminoglycans, plant cell wall polysaccharides, and bacterial capsule glycoglycerolipids. This product has also been shown to promote the migration of liver cancer cells (Huh7, SK-Hep1, and SNU449) through the induction of the EMT process.
- Critical precursor for essential glycoconjugates
- Supports the formation of mammalian glycosaminoglycans, plant cell wall polysaccharides, and bacterial capsule glycoglycerolipids
- Induces cell migration in liver cancer cell lines
- Decreases E-cadherin levels and increases vimentin levels in liver cancer cells
- Purity of 99.87%
- Appearance as a white to off-white solid
- For research use only
Medchemexpress LLC Ethyl glucuronide-d5 | 1135070-98-2 | 97.6% | 227.22 | 1 MG
Ethyl glucuronide-d5 is a deuterium labeled Ethyl glucuronide. It is an endogenous metabolite of ethanol and serves as a biomarker for ethanol exposure, accumulating in hair to reflect alcohol intake over time. It is also an agonist for TLR4. This product is for research use only.
- Deuterium labeled compound
- Stable heavy isotope
- Tracer for quantitation during drug development
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Used as a tracer
- Can be used as an internal standard for quantitative analysis
- Potential to affect the pharmacokinetic and metabolic profiles of drugs (due to deuteration)
Apexbio Technology LLC 7-Methoxycoumarin-4-acetyl-P-L-G-L-β-(2,4-dinitrophenylamino)A-R amide 140430-53-1 5mg
7-Methoxycoumarin-4-acetyl-P-L-G-L-beta-24-dinitrophenylamino A-R amide (CAS 140430-53-1) is a fluorogenic peptide substrate targeting matrix metalloproteinases (MMPs) It is designed to enable the continuous measurement of MMP enzymatic activity which is achieved by monitoring substrate cleavage between Gly and Leu residues 7-Methoxycoumarin-4-acetyl-P-L-G-L-beta-24-dinitrophenylamino A-R amide exerts its utility through a fluorescence-based mechanism cleavage by MMPs separates the fluorescent reporter group from the quencher resulting in increased fluorescence signal Based on these properties 7-Methoxycoumarin-4-acetyl-P-L-G-L-beta-24-dinitrophenylamino A-R amide is employed in biochemical assays for the quantification of total or specific MMP activity in biological samples and enzyme preparations
Medchemexpress LLC 1-Propanone, 3-(2,4-dihydroxy-6-methoxyphenyl)-1-(4-hydroxyphenyl)- | 119425-91-1 | 10 MG
Loureirin D is a dihydrochalcone found in dragon's blood. This product is for research use only and has not been fully validated for medical applications.
- Dihydrochalcone found in dragon's blood
- Purity of 99.30%
- Molecular formula: C16H16O5
- Molecular weight: 288.30
- Appears as a white to pink solid
- Store at 4°C, protected from light
- Store in solvent at -80°C for 6 months or -20°C for 1 month, protected from light
- Soluble in DMSO (≥ 50 mg/mL)
- Structure consistent with 1H NMR and LCMS
Apexbio Technology LLC HyperTrap Heparin HP Column(Synonyms: Heparin Affinity Column, Heparin HP Column, HyperTrap Heparin Affinity Chromatography Column), 1ml.
HyperTrap Heparin HP Column features the HyperChrom Heparin HP Agarose affinity chromatography resin which consists of heparin covalently immobilized on an agarose matrix Heparin is a naturally occurring glycosaminoglycan known for specific affinity interactions with various biomolecules including coagulation factors growth factors interferons lipoprotein lipase nucleic acid-binding proteins steroid receptors and antithrombin III This column enables efficient separation and purification of these proteins making it suitable for biochemical research proteomics analyses and protein characterization studies