Lipids and Lipid Derivatives
Apexbio Technology LLC Pasireotide Acetate 396091-76-2 10mg
Pasireotide Acetate (CAS 396091-76-2) is a cyclohexapeptide somatostatin analog that acts as a multi-receptor ligand selectively activating several somatostatin receptor subtypes (sst1/2/3/5 with pKi values of 8 2 9 0 9 1 and 9 9 respectively) By modulating these receptors Pasireotide Acetate regulates the secretion of growth hormone insulin-like growth factor I (IGF-I) and adrenocorticotropic hormone (ACTH) at the cellular level Preclinical investigations indicate its capacity to alter endocrine hormone release with implications for studies in acromegaly and Cushing s disease Its demonstrated effects on secretion inhibition proliferation control and induction of apoptosis make it a valuable tool in studies of related biological pathways
Medchemexpress LLC KY-02327 acetate | 2989396-34-9 | 99.2% | 433.50 g/mol | C22H31N3O6 | 10MM 1ML
KY-02327 acetate is a small-molecule inhibitor of the Dishevelled (Dvl)-CXXC5 interaction that activates the Wnt/β-catenin signaling pathway. It is supplied as a solution in DMSO for cell biology and biochemical assays and is commonly used to study osteoblast differentiation and pathway modulation. The compound has formula C22H31N3O6, molecular weight 433.50 g/mol, and reported purity ~99.2%.
- Provided as a ready-to-use solution for rapid experimental setup.
- Reported high purity to minimize impurity-related effects.
- Suitable for Wnt pathway and osteoblast differentiation studies.
- Available in solid form for custom formulation or storage.
- Compact packaging reduces storage footprint and waste.
- Stable under recommended storage conditions for reliable results.
Apexbio Technology LLC nor-NOHA (acetate) 1140844-63-8 10mg
nor-NOHA (acetate) (CAS 1140844-63-8) is a potent reversible inhibitor of rat liver arginase (Ki 0 5 M) By competitively inhibiting arginase nor-NOHA modulates the cellular balance between the L-arginine-dependent pathways of nitric oxide synthase (NOS) and arginase affecting nitric oxide production and urea cycle metabolism In vitro studies have shown that nor-NOHA suppresses proliferation migration and invasion of HepG2 hepatocellular carcinoma cells induces apoptosis and alters expression of Arg1 MMP-2 P53 and ECD In vivo nor-NOHA improves endothelial function in rat models of inflammation by enhancing NOS activity increasing EDHF and reducing superoxide anion production This compound is widely used to investigate arginase-related mechanisms in cellular and vascular biology
Medchemexpress LLC Farnesyl pyrophosphate ammonium | 116057-57-9 | 95.4% | 433.42 | 10 MG
Farnesyl pyrophosphate ammonium | 116057-57-9 | 95.4% | 433.42 | 10 MG
Abcam Octyl-beta-D-thioglucopyranoside, APG surfactant
MW 308.44 Da, Purity >98%. APG surfactant. Reagent for the solubilisation and isolation of membranes.
TARGETMOL CHEMICALS INC Ko 143 10MG
Also available in 1 mL, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Ko 143 is a selective inhibitor of ATP-binding cassette sub-family G member 2 (ABCG2; BCRP). Purity 99.89%
TARGETMOL CHEMICALS INC SPI-112 50MG
Also available in 1 mL, 10 mg, 25 mg and bulk. Please contact Fisher for quotes. SPI-112, the SPI-112 methyl ester analog, can inhibit cellular Shp2 PTP activity. SPI-112 bound to Shp2 by surface plasmon resonance (SPR) and displayed competitive inhibitor kinetics to Shp2. Purity 100%
TARGETMOL CHEMICALS INC Oxytocin acetate 50MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 100 mg and bulk. Please contact Fisher for quotes. Oxytocin acetate (alpha-Hypophamine acetate) is a mammalian neurohypophysial hormone, a ligand of oxytocin receptor.
Medchemexpress LLC PRT062607 acetate | 1370261-98-5 | C21H27N9O3 | 100 MG
PRT062607 acetate is a solid chemical identified for laboratory use and substance manufacturing. It is recommended to store this product at 4°C, sealed and away from moisture. When in solvent, store at -80°C for up to 6 months or -20°C for 1 month, also sealed and away from moisture. Shipping at room temperature is acceptable for periods less than 2 weeks.
- Identified for laboratory chemicals and manufacture of substances
- Stable under recommended storage conditions
- Recommended storage at 4°C, sealed, away from moisture
- Storage in solvent at -80°C for 6 months or -20°C for 1 month, sealed, away from moisture
- Appearance: Solid
Medchemexpress LLC Lefamulin acetate | 1350636-82-6 | 99.7% | 567.78 | 1 ML
Lefamulin acetate is an orally active antibiotic that inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. It also demonstrates anti-inflammatory activity and is utilized in research pertaining to bacterial infections, such as bacterial pneumonia.
- Inhibits protein synthesis by binding to 50S bacterial ribosome.
- Exhibits anti-inflammatory activity.
- Effective against C. trachomatis, N. gonorrhoeae, and M. genitalium.
- Potent activity against M. pneumoniae strains.
- Shows antibacterial effect in S. pneumoniae or S. aureus challenged lung infection mice.
- Reduces BALF neutrophil cell counts and levels of pro-inflammatory cytokines and chemokines in LPS-induced lung neutrophilia mouse model.
Medchemexpress LLC Sifuvirtide acetate | 99.8% | 4727.98 | 1 MG
Sifuvirtide acetate is a potent HIV fusion inhibitor. It inhibits HIV-1 mediated cell fusion in a dose-dependent manner and is highly potent against infection by primary and laboratory-adapted HIV-1 isolates of multiple genotypes. Sifuvirtide acetate can be used in the research of anti-HIV drugs.
- Potent HIV fusion inhibitor
- Inhibits HIV-1 mediated cell fusion in a dose-dependent manner
- Highly potent against infection by primary and laboratory-adapted HIV-1 isolates of multiple genotypes
- Can be used in the research of anti-HIV drugs
Medchemexpress LLC NN1213 acetate | 99.7% | 4553.10 (free base) | 10 MG
NN1213 acetate is a long-acting human amylin peptide analog and a selective amylin receptor agonist. It has EC50 values of 0.177 nM for hAMY3R and 0.262 nM for rAMY3R. This compound significantly reduces food intake and fat mass, leading to body weight reduction in diet-induced obese rats, making it suitable for obesity research.
- Selective amylin receptor agonist
- EC50 values of 0.177 nM for hAMY3R and 0.262 nM for rAMY3R
- Produces dose-dependent body weight loss in diet-induced obese rats
- Reduces food intake in rats and beagle dogs
- Decreases body weight and food intake in diet-induced obese rats
Medchemexpress LLC LSD (acetate) | 945245-76-1 | 98.0% | 1009.20 | 10 MG
LSD acetate is a peptide utilized in targeted therapy and diagnosis research for tumor lymphatics. It specifically recognizes the lymphatics of C8161 melanoma, without binding to normal tissue lymphatics or tumor blood vessels. When conjugated with a proapoptotic peptide, it can effectively reduce the number of tumor lymphatics.
- Recognizes C8161 melanoma lymphatics
- Does not bind to normal tissue lymphatics or tumor blood vessels
- Reduces tumor lymphatics when conjugated with proapoptotic peptides
- Suitable for targeted therapy research
- Suitable for diagnosis of tumor lymphatics
Medchemexpress LLC DALDA (acetate) | 99.8% | 671.79 | 10 MG
DALDA acetate is a potent and highly selective μ-opioid receptor agonist with a Kᵢ of 1.69 nM. It exhibits antinociceptive and respiratory effects. This compound carries a net positive charge (3+) at physiological pH, making it hydrophilic and more polar than morphine.
- Potent and highly selective μ-opioid receptor agonist
- Kᵢ of 1.69 nM
- Exhibits antinociceptive effects
- Exhibits respiratory effects
- Carries a net positive charge (3+) at physiological pH
- More polar than morphine