Drug Standards
Selleck Chemical LLC Betamethasone Valerate 25mg 2152-44-5
Betamethasone Valerate is a moderately potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Cayman Chemical CabazItaxel-d9 1mg
An internal standard for the quantification of cabazitaxel by GC- or LC-MS
Medchemexpress LLC S-Diclofenac | 912758-00-0 | C23H15Cl2NO2S3 | 50 MG
S-Diclofenac (ACS 15) is a hybrid molecule combining an H2S donor and the NSAID diclofenac. It activates the p53 signaling pathway, inhibits JNK activation, and exhibits antioxidant and anti-inflammatory activities.
- Activates p53 signaling pathway
- Inhibits JNK activation
- Acts as an antioxidant
- Acts as an anti-inflammatory
- Induces p53 protein expression and apoptosis in rat aortic vascular smooth muscle cells
- Ameliorates hindpaw edema in rat models
- Reduces myocardial injury and cardiac dysfunction in mouse models
- Has a purity of 99.20%
- Appearance: reddish brown to red solid
Medchemexpress LLC Ruxolitinib phosphate (synonyms: INCB018424 phosphate) | 1092939-17-7 | MFCD29938883 | 99.97% | C17H18N6.H3PO4 | 500 MG
Ruxolitinib phosphate, also known as INCB018424 phosphate, is a potent inhibitor of JAK1 and JAK2, with IC50s of 3.3 nM and 2.8 nM, respectively. It exhibits over 130-fold selectivity for JAK3, making it a highly selective compound for research applications. This inhibitor also effectively suppresses JAK2V617F-mediated signaling and proliferation, and inhibits HEL cell growth at an EC50 of 186 nM.
- Potent JAK1/2 inhibitor
- Highly selective over JAK3
- Inhibits JAK2V617F-mediated signaling
- Suppresses HEL cell growth
- Increases apoptosis in Ba/F3-EpoR-JAK2V617F cell systems
- Inhibits hematopoietic progenitor cell proliferation
- Reduces tumor burden in vivo without anemia or lymphopenia
Selleck Chemical LLC Methotrexate S1210-500mg
Methotrexate analog of folic acid is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells It forms an inactive ternary complex with DHFR and NADPH Methotrexate (MTX) induces apoptosis
Medchemexpress LLC Ticagrelor impurity 16 | 2096989-56-7 | 99.5% | C23H28F2N6O4S | 5 MG
Ticagrelor impurity 16 is an impurity of Ticagrelor, intended for research use only. It is a solid with a molecular weight of 522.57.
- Impurity of ticagrelor
- Solid form
- Molecular weight of 522.57
- Intended for research use only
- Store at room temperature for 3 years
- Store in solvent at -80°C for 2 years
- Store in solvent at -20°C for 1 year
Medchemexpress LLC N-desalkylflurazepam | 2886-65-9 | MFCD00083443 | 100.0% | 288.70 g/mol | C15H10ClFN2O | 5 MG
N-desalkylflurazepam is a benzodiazepine metabolite supplied as a high-purity analytical standard for research and analytical applications. It is suited for chromatographic and mass spectrometric assays, method development, and quality control.
- Analytical standard for benzodiazepine metabolite testing.
- High purity for reliable reference and quality-control measurements.
- Molecular formula C15H10ClFN2O and molecular weight 288.70 g/mol.
- Available in small milligram pack sizes tailored for analytical use.
- Provided with datasheet detailing handling and storage.
Medchemexpress LLC Norfloxacin (MK-0366) | 70458-96-7 | MFCD00079532 | 98.3% | 5 G
Norfloxacin (MK-0366) is a broad-spectrum antibiotic effective against both Gram-positive and Gram-negative bacteria. Its mechanism of action involves inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV. These enzymes are crucial for the separation of bacterial DNA, and their inhibition by Norfloxacin consequently prevents bacterial cell division. This synthetic chemotherapeutic antibacterial agent is occasionally utilized to treat both common and complicated urinary tract infections. The product is intended for research use only.
- Broad-spectrum antibiotic
- Effective against Gram-positive and Gram-negative bacteria
- Inhibits DNA gyrase and topoisomerase IV
- Prevents bacterial cell division
- Suitable for research applications
Medchemexpress LLC Escitalopram (oxalate) | 219861-08-2 | 99.9% | 414.43 | 10 MG
Escitalopram oxalate, the S-enantiomer of racemic Citalopram, is a selective serotonin reuptake inhibitor (SSRI). It exhibits approximately 30-fold higher binding affinity than its R(-)-enantiomer and demonstrates selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). This compound is an antidepressant used in research for major depression, intended for research use only.
- Selective serotonin reuptake inhibitor (SSRI)
- Exhibits approximately 30-fold higher binding affinity than its R(-)-enantiomer
- Demonstrates selectivity over dopamine and norepinephrine transporters
- Ameliorates cognitive impairments and attenuates phosphorylated tau accumulation in stressed rats
- Significantly reduces plaque load in APP-PS1 hemizygous female mice
Medchemexpress LLC Amodiaquine impurity 1 | 81099-86-7 | 98.7% | 270.72 | 1 G
Amodiaquine impurity 1 is a chemical compound with the molecular formula C15H11ClN2O, appearing as a light yellow to yellow solid. It is intended for use as a laboratory chemical and in the manufacture of substances.
- High purity of 98.70% by HPLC
- Molecular formula: C15H11ClN2O
- Appearance: light yellow to yellow solid
- Stable under recommended storage conditions
- Requires protection from light and storage under nitrogen
Sigma Aldrich Fine Chemicals Biosciences Lidocaine British Pharmacopoeia (BP) Reference Standard | 137-58-6 | MFCD00026733 |
Lidocaine British Pharmacopoeia (BP) Reference Standard | Mol Wt: 234.34 | 137-58-6 | MFCD00026733 |
Cayman Chemical GlyburIde-d3 1mg
An internal standard for the quantification of glyburide by GC- or LC-MS
Medchemexpress LLC Ethacrynic acid | 58-54-8 | 98.8% | 5 MG
Ethacrynic acid (Standard) is an analytical standard of Ethacrynic acid, used in research and analytical applications. It functions as a diuretic and an inhibitor of glutathione S-transferases (GSTs). It also potently inhibits the NF-kB-signaling pathway, modulates leukotriene formation, and inhibits L-type voltage-dependent and store-operated calcium channels, leading to relaxation of airway smooth muscle (ASM) cells.
- Functions as a diuretic
- Inhibits glutathione S-transferases (GSTs)
- Potently inhibits the NF-kB-signaling pathway
- Modulates leukotriene formation
- Inhibits L-type voltage-dependent and store-operated calcium channels
- Reduces retinoid-induced ear edema in mice (anti-inflammatory)
- Used as a reference standard for assays
- Suitable for HPLC, GC, and MS experiments
Medchemexpress LLC Ticagrelor impurity 6 | 2216753-87-4 | 99.1% | C23H28F2N6O4S | 1 MG
Ticagrelor impurity 6 is a high-purity chemical compound, presenting as a white to off-white solid. It has a molecular weight of 522.57 and a chemical formula of C23H28F2N6O4S. This substance serves as an impurity of Ticagrelor.
- Impurity of ticagrelor
- High purity (99.12%) for research applications
- White to off-white solid appearance
- Suitable for laboratory chemical uses
- Identified as a drug intermediate
Medchemexpress LLC Flavopiridol hydrochloride (alvocidib hydrochloride) | 131740-09-5 | MFCD26792554 | 438.30 g/mol | C21H21Cl2NO5 | 10 MG
Flavopiridol hydrochloride (alvocidib) is an ATP-competitive, broad-spectrum cyclin-dependent kinase (CDK) inhibitor used in research to probe cell-cycle control, autophagy, and viral pathways. The hydrochloride salt enhances solubility for in vitro and in vivo applications; manufacturer datasheet provides IC50s, solubility, storage, and formulation guidance for stock and dosing preparation.
- ATP-competitive cyclin-dependent kinase inhibitor.
- Reported IC50s: CDK1 30 nM, CDK2 170 nM, CDK4 100 nM.
- High solubility in DMSO and water (≥20 mg/mL) for stock solutions.
- Includes in vivo formulation guidance for dosing preparations.
- Stability in solvent: -80°C (1 year) and -20°C (6 months) when sealed.
- Molecular weight 438.30 g/mol and formula C21H21Cl2NO5 for accurate calculations.