Hydrobromides
Medchemexpress LLC Eletriptan hydrobromide | 177834-92-3 | 99.8% | C22H27BrN2O2S | 1 ML
Eletriptan hydrobromide is a 5-HT1B and 5-HT1D receptor agonist with antimigraine activity, primarily used as a laboratory chemical for research purposes. It appears as an off-white to light brown solid with a molecular weight of 463.43.
- 5-HT1B and 5-HT1D receptor agonist
- Demonstrates antimigraine activity
- Ki values of 0.92 nM for 5-HT1B receptor
- Ki values of 3.14 nM for 5-HT1D receptor
- Off-white to light brown solid appearance
- Reduces carotid blood flow in anesthetized dogs (in vivo)
- Inhibits dural plasma protein extravasation in anesthetized rats (in vivo)
Medchemexpress LLC Scopolamine hydrobromide trihydrate | 6533-68-2 | MFCD00150066 | 99.9% | 438.31 | 100 MG
Scopolamine hydrobromide trihydrate is a high-affinity muscarinic antagonist that can cross the blood-brain barrier. It acts as a competitive antagonist of 5-HT3 receptors. This compound can induce cognitive and memory deficits in animals and is used in research.
- High-affinity muscarinic antagonist
- Crosses the blood-brain barrier
- Competitive antagonist of 5-HT3 receptors
- Induces cognitive and memory deficits in animals
- Used in research for preventing postoperative nausea and vomiting
- Used in research for motion sickness
- Used in research for nervous system diseases
Medchemexpress LLC S-EIT hydrobromide 25g
S-EIT (hydrobromide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Apexbio Technology LLC Arecoline hydrobromide 300-08-3 1g
Arecoline hydrobromide (CAS 300-08-3) is a nicotinic alkaloid that acts as a partial agonist at muscarinic acetylcholine receptors M1 M4 In electrophysiological studies it significantly inhibits the hERG potassium channel current with an IC50 of 9 55 mol/L The compound s inhibitory effect on IhERG displays concentration time and voltage dependency with blockade intensity influenced by stimulation frequency Subcutaneous administration in mice yields an LD50 of 100 mg/kg Arecoline hydrobromide is utilized in research on cardiac electrophysiology and muscarinic receptor pharmacology particularly for investigating frequency- and state-dependent modulation of cardiac ion channels
Medchemexpress LLC Rociletinib hydrobromide | 1446700-26-0 | MFCD28386290 | 98.0% | 636.46 g/mol | C27H29BrF3N7O3 | 10 MG
Rociletinib hydrobromide is the hydrobromide salt of rociletinib, an orally active kinase inhibitor selective for mutant forms of the epidermal growth factor receptor (EGFR) including T790M. It is supplied as a solid research reagent for biochemical, cellular, and analytical studies.
- Hydrobromide salt of rociletinib.
- Selective inhibitor of mutant EGFR, including T790M.
- Intended for research and analytical applications.
- Purity 98.04% (HPLC).
- Molecular weight 636.46 g/mol.
- CAS number 1446700-26-0.
- Store sealed, away from moisture; in solvent: -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Oxidopamine (hydrobromide) | 636-00-0 | 99.4% | 500 MG
Oxidopamine (6-OHDA) hydrobromide is a potent neurotoxin that selectively destroys dopaminergic neurons by acting as an antagonist of the neurotransmitter dopamine. It is a valuable tool for research into various neurological conditions, including Parkinson's disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome. The compound also promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion.
- Selectively destroys dopaminergic neurons
- Antagonist of dopamine neurotransmitter
- Promotes COX-2 activation and PGE2 synthesis
- Induces pro-inflammatory cytokine IL-1β secretion
- Useful for Parkinson's disease research models
- Applicable in ADHD and Lesch-Nyhan syndrome studies
Medchemexpress LLC Fenoterol hydrobromide | 1944-12-3 | 100.0% | 1 ML
Fenoterol hydrobromide (Th-1165a) is a sympathomimetic agent that acts as a selective and orally active β2-adrenoceptor agonist. It is an effective bronchodilator, making it suitable for research into bronchospasm associated with asthma, bronchitis, and other obstructive airway diseases.
- Selective and orally active β2-adrenoceptor agonist
- Functions as an effective bronchodilator
- Used in research for bronchospasm associated with asthma, bronchitis, and other obstructive airway diseases
Medchemexpress LLC 1,4-PBIT (dihydrobromide) | 157254-60-9 | 98.0% | 444.25 g·mol⁻¹ | C12H20Br2N4S2 | 5 MG
1,4-PBIT (dihydrobromide) is a research-grade small-molecule inhibitor of nitric oxide synthases provided as the dihydrobromide salt (CAS 157254-60-9). Supplied in small-mass vials for biochemical and pharmacological studies, the compound is characterized by analytical documentation and high purity suitable for in vitro research.
- Potent inhibitor of iNOS, eNOS, and nNOS isoforms.
- High purity for reliable experimental results.
- Available in small-mass vials suitable for medicinal chemistry applications.
- Stable dihydrobromide salt form for consistent handling.
- Documented analytical data and certificate of analysis available.
Medchemexpress LLC Amthamine dihydrobromide | 142457-00-9 | MFCD00673891 | 99.6% | 319.07 g/mol | C6H13Br2N3S | 10 MG
Amthamine dihydrobromide is the dihydrobromide salt of amthamine, a histamine receptor agonist active at H1-H4 subtypes. It is supplied for research use to investigate histamine receptor pharmacology, gastric acid secretion, and hepatotoxicity models. Follow standard laboratory safety and storage recommendations.
- High purity (99.6%) suitable for biochemical and pharmacological studies.
- Molecular weight 319.07 g/mol.
- Chemical formula C6H13Br2N3S.
- CAS number 142457-00-9 for unambiguous identification.
- Available in small research quantities, such as 10 MG, for laboratory use.
- Stable when stored sealed and kept away from moisture; refrigerated storage extends stability.
Medchemexpress LLC Eletriptan hydrobromide | 177834-92-3 | MFCD08141806 | 463.43 g/mol | C22H27BrN2O2S | 10 MG
Eletriptan hydrobromide is the hydrobromide salt of eletriptan, a selective 5-HT1B and 5-HT1D receptor agonist supplied as an analytical standard for laboratory and research use.
- Analytical standard suitable for research and assay development.
- Selective 5-HT1B and 5-HT1D agonist for pharmacology studies.
- Reported Ki values: 0.92 nM (5-HT1B) and 3.14 nM (5-HT1D).
- Chemical formula C22H27BrN2O2S; molecular weight ~463.4 g/mol.
- Provided in small masses appropriate for analytical work.
Medchemexpress LLC Pifithrin-β hydrobromide | 511296-88-1 | MFCD02683960 | >=98.0% | 349.29 g/mol | C16H17BrN2S | 10 MG
Pifithrin-β hydrobromide is a small-molecule inhibitor of the p53 pathway supplied as the hydrobromide salt. It reversibly blocks p53 transcriptional activity (reported IC50 = 23 μM) and is used as a research tool in cellular and biochemical studies of apoptosis and ferroptosis. Chemical formula C16H17BrN2S; molecular weight 349.29 g/mol; CAS 511296-88-1.
- Reversible p53 inhibitor with reported IC50 of 23 μM.
- Hydrobromide salt for improved solubility and handling.
- Reported high purity (≥98% by HPLC) in supplier listings.
- Suitable for cellular and biochemical assays studying apoptosis and ferroptosis.
- Store sealed at 4 °C as a solid; in solution store at -80 °C for long-term stability.
Medchemexpress LLC Nan-190 hydrobromide | 115338-32-4 | 99.1% | 474.39 | 50 MG
NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist. NAN-190 is a selective antagonist of 5-HT1A.
- Serotonin receptor 5-HT antagonist
- Selective antagonist of 5-HT1A
- IC50 & Target: 5-HT1A Receptor, 5-HT1 Receptor
- Reverses the catalepsy-improving effect of fluoxetine in 6-OHDA lesioned rats when injected at 0.5 mg/kg (ip) concomitantly with fluoxetine
TARGETMOL CHEMICALS INC VORTIOXETINE HYDROBROMID 100MG
Also available in 10 mg 25 mg 50 mg 200 mg 500 mg 1000 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Vortioxetine hydrobromide (Lu AA21004 hydrobromide) is a serotonin (5-HT) modulator and stimulator (SMS) inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50 15/33/3.7/19/1.6 nM). purity: 99%
TARGETMOL CHEMICALS INC PIFITHRIN-ALPHA HYDROBRO 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Pifithrin-(alpha) hydrobromide (Pifithrin-(alpha) hydrobromide) is a p53 inhibitor inhibiting p53-dependent transactivation of p53-responsive genes. purity: 98%
Medchemexpress LLC Halofuginone (hydrobromide) | 64924-67-0 | 495.59 | 25 MG
Halofuginone hydrobromide, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor. It specifically inhibits type-I collagen synthesis and helps reduce osteoarthritis by inhibiting TGF-β activity. It also acts as a potent pulmonary vasodilator by activating Kv channels and blocking various Ca2+ channels. This compound exhibits a range of beneficial effects.
- Competitively inhibits prolyl-tRNA synthetase
- Inhibits type-I collagen synthesis
- Attenuates osteoarthritis by inhibiting TGF-β activity
- Potent pulmonary vasodilator
- Activates Kv channels and blocks Ca2+ channels
- Exhibits anti-malaria effects
- Provides anti-inflammatory effects
- Shows anti-cancer activity
- Offers anti-fibrosis effects
- Decreases NRF2 protein levels in tumors