Hydrobromides
Medchemexpress LLC SCH-202676 (hydrobromide) | 265980-25-4 | 96.8% | 348.26 | 1 ML
SCH-202676 hydrobromide is an allosteric modulator of G protein-coupled receptors (GPCRs) and adenosine receptor (AR). It demonstrates antiviral activity and inhibits 3CLpro in a time-dependent manner with an IC50 value of 0.655 μM.
- Purity: 96.81%
- Appearance: Solid
- Color: White to off-white
- Solubility: DMSO: 10 mg/mL
![Medchemexpress LLC Piperidine, 4-[2-[(4-methylphenyl)thio]phenyl]-, hydrobromide | 960151-65-9 | 99.8% | 364.34 g/mol | C18H22BrNS | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000249020.png-250.jpg)
Medchemexpress LLC Piperidine, 4-[2-[(4-methylphenyl)thio]phenyl]-, hydrobromide | 960151-65-9 | 99.8% | 364.34 g/mol | C18H22BrNS | 1 ML
Tedatioxetine hydrobromide is the hydrobromide salt of tedatioxetine, a serotonin- and norepinephrine-preferring triple reuptake inhibitor that also antagonizes 5-HT2A, 5-HT2C, 5-HT3, and α1A-adrenergic receptors. It is supplied for research use as a solid and as a 10 mM solution in DMSO, intended for in vitro transporter and receptor pharmacology studies.
- High purity (99.83%) suitable for research applications.
- Supplied as solid and as a 10 mM solution in DMSO (1 mL).
- Suitable for transporter and receptor pharmacology assays.
- Molecular formula C18H22BrNS; molecular weight 364.34 g/mol.
- Store sealed, away from moisture; in solvent: -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC CPTH6 hydrobromide 10mg | 2321332-57-2 | 386.74 g/mol | C15H17BrClN3S | 10 MG
CPTH6 hydrobromide is the hydrobromide salt of a thiazole-derived small molecule used to study histone acetylation, apoptosis, and autophagy in cancer cell models. It is supplied as a white to off-white solid with high reported purity and good solubility in polar solvents.
- Inhibits histone acetyltransferase activity, reported for Gcn5 and pCAF.
- Induces apoptotic and autophagic features in leukemia cell lines.
- Supplied as a hydrobromide salt for improved handling and solubility.
- High purity suitable for research applications (≥99.0%).
- Soluble in DMSO (≈66.67 mg/mL) for in vitro assays.
- Store sealed at -20°C; in solution, store at -80°C for long-term stability.
Medchemexpress LLC Pyrithiamine hydrobromide | 534-64-5 | 96.6% | 25 MG
Pyrithiamine hydrobromide is a thiamine metabolic inhibitor supplied as a high-purity solid for laboratory research. It is used to study thiamine-dependent biochemical pathways and nervous system disease models.
- Thiamine metabolic inhibitor for biochemical research.
- Acts as a substrate for thiamine pyrophosphokinase.
- Purity 96.6% (manufacturer reported).
- Molecular formula C14H20Br2N4O and molecular weight 420.14 g·mol⁻¹.
- CAS number 534-64-5.
- Supplied as a 25 MG solid for laboratory use; not for human consumption.
Medchemexpress LLC Dihydro-β-erythroidine hydrobromide | 29734-68-7 | MFCD00153793 | >98.0% | 356.25 g/mol | C16H22BrNO3 | 10 MG
Dihydro-β-erythroidine hydrobromide is a competitive antagonist of neuronal nicotinic acetylcholine receptors (nAChRs), with selectivity for α4β2 and α4β4 subtypes. It is used as a pharmacological tool in receptor characterization, electrophysiology, and behavioral studies to probe cholinergic signaling.
- Competitive nAChR antagonist selective for α4β2 and α4β4.
- CAS number 29734-68-7.
- Chemical formula C16H22BrNO3; molecular weight 356.25 g/mol.
- Purity >98.0% (HPLC) as reported by catalog vendors.
- Typical research pack sizes: 1 mg, 5 mg, 10 mg.
- Common applications: electrophysiology, receptor pharmacology, and behavioral assays.
TARGETMOL CHEMICALS INC VORTIOXETINE HYDROBROMID 100MG
Also available in 10 mg 25 mg 50 mg 200 mg 500 mg 1000 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Vortioxetine hydrobromide (Lu AA21004 hydrobromide) is a serotonin (5-HT) modulator and stimulator (SMS) inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50 15/33/3.7/19/1.6 nM). purity: 99%
Medchemexpress LLC Vortioxetine hydrobromide | 960203-27-4 | MFCD22383961 | C18H23BrN2S | 50 MG
Vortioxetine hydrobromide is a multimodal serotonergic agent exhibiting antidepressant and anxiolytic potential. It functions as an antagonist of 5-HT3A and 5-HT7 receptors, an inhibitor of the 5-hydroxytryptamine transporter (SERT), a 5-HT1A agonist, and a partial 5-HT1B agonist. Research indicates its ability to increase cell proliferation and survival in the dentate gyrus of the hippocampus.
- Antagonizes 5-HT3A and 5-HT7 receptors
- Inhibits 5-hydroxytryptamine transporter (SERT)
- Acts as a 5-HT1A receptor agonist
- Functions as a partial 5-HT1B receptor agonist
- Demonstrates antidepressant and anxiolytic properties
- Increases cell proliferation and survival in the hippocampus
- Does not cause cognitive or psychomotor impairment
Medchemexpress LLC Burixafor hydrobromide | 1191450-19-7 | 98.0% | 769.01 | 200 MG
Burixafor (TG-0054) hydrobromide is a potent CXCR4 antagonist with a pIC50 of 7.4. It inhibits the binding of CXCL12 to CXCR4, antagonizes CXCL12-induced recruitment of Gαᵢ and β-arrestin2, and blocks the downstream Gαᵢ-mediated inhibitory effect on cAMP signal transduction. It mobilizes CD34+ hematopoietic stem/progenitor cells (HSPC) from the bone marrow to the peripheral blood and can be used for research on autologous hematopoietic stem cell transplantation (ASCT).
- Potent CXCR4 antagonist (pIC50 of 7.4)
- Inhibits CXCL12 binding to CXCR4
- Antagonizes CXCL12-induced recruitment of Gαᵢ and β-arrestin2
- Blocks downstream Gαᵢ-mediated inhibitory effect on cAMP signal transduction
- Mobilizes CD34+ hematopoietic stem/progenitor cells (HSPC) from bone marrow to peripheral blood
- Potential for research on autologous hematopoietic stem cell transplantation (ASCT)
Medchemexpress LLC BC-11 hydrobromide | 443776-49-6 | 99.0% | 290.97 g/mol | C8H12BBrN2O2S | 5 MG
BC-11 hydrobromide is a research-grade small-molecule inhibitor that targets TMPRSS2 and urokinase (uPA). It is used in biochemical and cellular studies of viral entry and cancer biology, and is supplied as a hydrobromide salt to aid stability and handling.
- Selective TMPRSS2 and urokinase (uPA) inhibition for mechanistic studies.
- Suitable for biochemical and cellular assays, including viral entry research.
- Hydrobromide salt form for improved stability and solubility.
- High purity (99.0%) and available in small research sizes (5-100 mg).
Apexbio Technology LLC Homatropine Bromide 51-56-9 10mM (in 1mL DMSO)
Homatropine Bromide (CAS 51-56-9) is a small molecule antagonist of muscarinic acetylcholine receptors (AChRs) It selectively inhibits muscarinic receptor-mediated responses in endothelial and smooth muscle cells with reported IC50 values of 162 5 nM and 170 3 nM for WKY-E and SHR-E cell models respectively This compound serves as a valuable tool for investigating the role of muscarinic signaling in vascular function and smooth muscle physiology within experimental research settings
Apexbio Technology LLC A 61603 hydrobromide 107756-30-9 10mg
A 61603 hydrobromide (CAS 107756-30-9) is a potent and highly selective agonist of the 1A-adrenergic receptor one of the 1-adrenergic receptor subtypes involved in cellular growth and proliferation Compared to its activity at 1B- and 1D-adrenergic receptors A 61603 demonstrates approximately 35-fold higher potency for 1A-AR In cellular assays it robustly induces phosphoinositide hydrolysis in 1A-AR-expressing fibroblasts (pEC50 8 24) and in neonatal rat cardiomyocytes it increases calcium transient frequency in a dose-dependent manner (EC50 6 9 nM) In vascular models A 61603 markedly elevates perfusion pressure demonstrating significantly greater efficacy than noradrenaline This compound serves as a valuable tool for delineating 1A-AR-mediated signaling and vascular regulation
Medchemexpress LLC 2-iminobiotin hydrobromide | 76985-52-9 | 98.0% | 324.24 g/mol | C10H18BrN3O2S | 25 MG
2-Iminobiotin hydrobromide (CAS 76985-52-9) is a synthetic biotin analog and a reversible inhibitor of nitric oxide synthases (iNOS and nNOS). Supplied as a solid or as ready-to-use DMSO solutions, it is used in biochemical and cellular assays to modulate nitric oxide production and investigate NOS-related pathways.
- Reversible inhibition of iNOS and nNOS for targeted enzyme studies.
- Suitable for biochemical assays and cellular research.
- Available in solid form and as DMSO solutions for flexible dosing.
- High purity (≈98.0%) to support reproducible results.
- Molecular weight 324.24 g/mol and well-defined chemical identity (C10H18BrN3O2S).
Cayman Chemical Clobenpropit hydrobromide
A selective histamine H3 receptor antagonist (Ki = 0.17 nM in rat cortical membranes); reduces inhibition of electrically induced contractions in isolated guinea pig ileum longitudinal muscle by (R)-α-methylhistamine at 0.3, 0.1, and 3 nM; decreases the duration of the tonic, clonic, and convulsive coma phases of electrically induced convulsions in mice at 1 and 3 mg/kg, an effect that can be blocked by (R)-α-methylhistamine or imetit; increases GABA release and inhibits NMDA-induced neurotoxicity in primary rat cortical neurons at 0.1 μM
Apexbio Technology LLC Scopolamine hydrobromide 114-49-8 10mM (in 1mL DMSO)
Scopolamine hydrobromide (114-49-8) is a small-molecule antagonist targeting muscarinic acetylcholine receptors and serotonin 5-HT3 receptors It is designed to reversibly block these receptors thereby modulating cholinergic and serotonergic signaling pathways Scopolamine hydrobromide exerts its biological activity primarily through reversible antagonism of muscarinic receptors and inhibition of serotonin 5-HT3 receptor responses In receptor binding studies Scopolamine hydrobromide demonstrates antagonistic activity with reported IC50 values generally ranging from nanomolar to micromolar concentrations depending on the receptor subtype and experimental conditions Based on these pharmacological properties Scopolamine hydrobromide holds research potential in studies of neurotransmission cholinergic signaling gastrointestinal motility assays cognitive impairment models and emesis reflex investigations
Selleck Chemical LLC Homatropine Bromide S4025-50mg
Homatropine Bromide is an muscarinic AChR antagonist inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162 5 nM and 170 3 nM respectively