Hydrochlorides
Medchemexpress LLC BAY-6672 hydrochloride | 2247520-31-4 | C26H28BrCl2N3O3 | 1 ML
BAY-6672 hydrochloride is a chemical compound supplied as a solid, primarily intended for laboratory research and the manufacture of substances.
- Identified for laboratory chemical applications
- Recommended storage at 4°C under nitrogen, away from moisture
- Store in solvent at -80°C for 6 months or -20°C for 1 month, under nitrogen
- Ships at room temperature if transit is less than 2 weeks
- For research use only
Medchemexpress LLC Benzenepropanoic acid, ß-(aminomethyl)-4-chloro-, hydrochloride (1:1) | 28311-31-1 | 99.8% | C10H13Cl2NO2 | 1 ML
Baclofen hydrochloride is a lipophilic derivative of γ-aminobutyric acid (GABA) and an orally active, selective metabotropic GABAB receptor (GABABR) agonist. It mimics the action of GABA, producing slow presynaptic inhibition through the GABAB receptor. This compound exhibits high blood-brain barrier penetrance, making it suitable for muscle spasticity research.
- Orally active, selective GABAB receptor agonist.
- Mimics GABA action for slow presynaptic inhibition.
- Exhibits high blood-brain barrier penetrance.
- Increases cell viability in huntingtin-expressing striatal cells.
- Enhances chymotrypsin-like proteasome activity.
- Ameliorates motor deficits in Huntington's disease animal models.
- Reduces neuronal intranuclear inclusions in animal models.
Medchemexpress LLC K-604 dihydrochloride | 217094-32-1 | MFCD30738203 | >=98.0% | 575.64 | C23H32Cl2N6OS3 | 25 MG
K-604 dihydrochloride is a research reagent that selectively inhibits acyl-CoA:cholesterol acyltransferase 1 (ACAT-1), with a reported IC50 of 0.45 ± 0.06 μM. Supplied as the dihydrochloride salt, it is intended for biochemical and cellular studies probing ACAT-1 activity and cholesterol esterification pathways.
- Selective ACAT-1 inhibitor with reported IC50 of 0.45 ± 0.06 μM.
- Dihydrochloride salt form for improved solubility in polar solvents.
- Molecular weight 575.64 g/mol and formula C23H32Cl2N6OS3.
- Purity reported as ≥98% by HPLC in supplier and database listings.
- CAS number 217094-32-1 for unambiguous identification.
- Suitable for biochemical and cellular assays targeting cholesterol metabolism.
Medchemexpress LLC SKF-96365 hydrochlor 50mg
SKF-96365 hydrochloride is a potent TRP channel blocker and a store-operated Ca2 entry (SOCE) inhibitor SKF-96365 hydrochloride significantly inhibits hERG hKCNQ1/hKCNE1 hKir2 1 and hKv4 3 current and significantly prolongs the QTc interval in isolated guinea pig hearts SKF-96365 hydrochloride exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal cancer cells1]2]
Medchemexpress LLC Ly-272015 hydrochloride | 172895-15-7 | 99.5% | 372.89 | C21H25ClN2O2 | 25 MG
LY-272015 hydrochloride is the hydrochloride salt of LY-272015, an orally active and selective 5-HT2B receptor antagonist supplied as a high-purity solid for laboratory research. It is used to probe serotonergic signaling and downstream ERK2 phosphorylation in preclinical studies.
- Orally active, selective 5-HT2B receptor antagonist.
- Useful for research into serotonergic signaling and ERK2 phosphorylation.
- High purity (about 99.5%) for reliable experimental results.
- Off-white to light yellow solid, suitable for analytical handling.
- Stable when stored sealed at 4°C; in solvent: -80°C for 6 months, -20°C for 1 month.
- Available in small research quantities, including 25 MG.
Medchemexpress LLC ENMD-1068 hydrochloride | 2703451-51-6 | 98.3% | 319.87 | C15H30ClN3O2 | 10MM 1ML
ENMD-1068 hydrochloride is a selective protease-activated receptor 2 (PAR2) antagonist used in biochemical and cellular research to probe PAR2 signaling and related pathways such as TGF-β1/Smad. The compound is supplied as the hydrochloride salt with high reported purity and is offered both as a ready-to-use 10 mM solution in DMSO (1 mL) and in multiple solid pack sizes for flexibility in experimental workflows.
- Selective PAR2 antagonist suitable for signaling and fibrosis research.
- Provided as the hydrochloride salt with white to off-white appearance.
- Available as a 10 mM DMSO solution (1 mL) for immediate use in assays.
- Offered in solid quantities for custom formulation and dosing.
- High reported purity (~98.3%) and defined molecular weight for reliable dosing.
- Solubility data and storage recommendations provided for in vitro and in vivo use.
Medchemexpress LLC Arc 239 dihydrochloride | 55974-42-0 | MFCD02262215; MFCD16875414 | 99.2% | 480.43 | C24H31Cl2N3O3 | 5 MG
ARC 239 dihydrochloride is a small-molecule research compound that acts as a selective α2B/α2C adrenoceptor antagonist. It is supplied as a white to off-white solid intended for in vitro pharmacology and receptor-binding studies; reported binding data indicate greater affinity at α2B compared with α2A and α2C subtypes.
- Selective antagonist of α2B and α2C adrenoceptors.
- Reported pKd/pKi values indicate higher affinity for α2B subtype.
- High purity suitable for research applications.
- White to off-white solid form for convenient handling.
- Stable under recommended refrigerated storage.
- Useful for subtype-selective adrenergic receptor studies.
Medchemexpress LLC Piperoxan hydrochloride | 135-87-5 | 99.7% | 269.77 | C14H20ClNO2 | 10 MG
Piperoxan hydrochloride is a research chemical described as an α2 adrenoceptor antagonist and an early-generation antihistamine. Supplied as a solid for laboratory use, it is used as a reference compound in receptor pharmacology and biochemical studies.
- α2 adrenoceptor antagonist activity
- First-generation antihistamine properties
- High reported purity (about 99.7%) suitable for research
- Solid form supplied in small laboratory pack sizes
- Molecular formula C14H20ClNO2; molecular weight 269.77
Medchemexpress LLC Nisoxetine | 53179-07-0 | 98.6% | 100 MG
Nisoxetine is a potent and selective inhibitor of noradrenaline transporter (NET), with a Kd of 0.76 nM. It functions as an antidepressant and local anesthetic, capable of blocking voltage-gated sodium channels. This product is intended for research use only.
- Potently and selectively inhibits the noradrenaline transporter (NET) with a Kd of 0.76 nM.
- Acts as both an antidepressant and a local anesthetic.
- Can block voltage-gated sodium channels.
- Available in multiple quantities.
- Comes with a data sheet, COA, SDS, and handling instructions.
- Detailed solubility information provided for in vitro use.
Medchemexpress LLC Angoline hydrochloride | 21080-31-9 | 5 MG
Angoline hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline hydrochloride inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation.
- Potent and selective IL6/STAT3 signaling pathway inhibitor
- IC50 of 11.56 μM
- Inhibits STAT3 phosphorylation
- Inhibits its target gene expression
- Inhibits cancer cell proliferation
- Purity: >98%
eMolecules 28356-58-3 | 4-Pyridineacetic acid | Combi-Blocks | MFCD03701446 | 137.138 | C7H7NO2 | 98.000 | OC(=O)Cc1ccncc1 | 1g | 357561050
4-Pyridineacetic acid | Combi-Blocks | 28356-58-3 | MFCD03701446 | 137.138 | C7H7NO2 | 98.000 | OC(=O)Cc1ccncc1 | 1g | 357561050
Medchemexpress LLC N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid dihydrochloride | 35369-53-0 | MFCD04113603 | >95.0% | 461.34 | C20H26Cl2N2O6 | 1 ML
HBED dihydrochloride is an orally active, hexadentate phenolic aminocarboxylate iron chelator (N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid dihydrochloride) supplied for research use in solution and solid formats for studies of iron binding and chelation biology.
- Orally active hexadentate iron chelator.
- Suitable for iron chelation research and biochemical assays.
- Supplied as ready-to-use 10 mM in DMSO solution and as solid material.
- Solid sizes available: 100 mg, 250 mg, 500 mg, 1 g.
- Molecular weight 461.34; formula C20H26Cl2N2O6.
- Typical purity specification ≥95.0% (batch dependent).
Medchemexpress LLC T-3775440 hydrochloride | 1422535-52-1 | 99.1% | 346.85 g/mol | C18H23ClN4O | 5 MG
T-3775440 hydrochloride is a small-molecule, irreversible inhibitor of lysine-specific histone demethylase 1 (KDM1/LSD1) used in biochemical and cellular research. It is supplied as a light yellow to yellow solid with high purity and characterized solubility and storage recommendations.
- Irreversible KDM1/LSD1 inhibitor; IC50 = 2.1 nM.
- Molecular formula C18H23ClN4O; molecular weight 346.85 g/mol.
- Purity approximately 99.1% by HPLC.
- Physical state: light yellow to yellow solid.
- Solubility: DMSO ≥ 30.18 mg/mL; water 8.33 mg/mL with ultrasonic warming to 60°C.
- Storage: powder at 4°C under inert atmosphere; solutions: -80°C (6 months), -20°C (1 month).
- Supplied as a 5 mg quantity.
Medchemexpress LLC Zinterol hydrochloride | 38241-28-0 | 99.7% | C19H27ClN2O4S | 1 ML
Zinterol hydrochloride is a potent and selective β2-adrenoceptor agonist. It increases ICa in a concentration-dependent manner with an EC50 of 2.2 nM. This compound has been shown to induce ventricular arrhythmias in conscious heart failure rabbits at specific dosages. It is intended strictly for research purposes.
- Potent and selective β2-adrenoceptor agonist.
- Increases ICa with an EC50 of 2.2 nM.
- Induces ventricular arrhythmias in heart failure animal models.
- For research use only.
- High purity of 99.7%.
- Solid form can be stored at 4°C, sealed, away from moisture.
- Solution form can be stored at -80°C for 6 months or -20°C for 1 month, sealed, away from moisture.
Medchemexpress LLC Amibegron hydrochloride | 121524-09-2 | MFCD00886563 | >98.0% | 440.36 g/mol | C22H27Cl2NO4 | 1 MG
Amibegron hydrochloride is a selective β3-adrenoceptor agonist used in preclinical research. It exhibits an EC50 of 3.5 nM for β-adrenoceptors in rat colon and has reported anxiolytic and antidepressant activity. The compound is supplied as a purified solid for laboratory assays and bioactivity studies; consult the manufacturer's datasheet for handling and storage conditions.
- Molecular formula: C22H27Cl2NO4.
- Molecular weight: 440.36 g/mol.
- CAS number: 121524-09-2.
- Purity: >98.0% (HPLC).
- Target: β3-adrenoceptor (adrenergic receptor).
- Typical package sizes: 1 mg, 5 mg, 10 mg.
- Storage: -20°C sealed; in solution -80°C (6 months) or -20°C (1 month).