Hydrochlorides
Medchemexpress LLC Duloxetine metabolite Para-Naphthol Duloxetine | 949095-98-1 | 297.41 | 250 MG
Para-Naphthol Duloxetine is a metabolite of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor (SNRI).
- Synonym: Para-naphthol duloxetine
- CAS number: 949095-98-1
- Molecular weight: 297.41
- Molecular formula: C18H19NOS
- Appearance: Solid
- Color: White to off-white
- Storage for powder: -20°C for 3 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
- For research use only
Medchemexpress LLC RS-102221 hydrochloride | 187397-18-8 | 98.0% | 649.08 | C27H32ClF3N4O7S | 10 MG
RS-102221 hydrochloride is the hydrochloride salt of a selective 5-HT2C receptor antagonist used in pharmacology and neuroscience research. Supplied for preclinical and in vitro studies, it provides selective blockade of 5-HT2C receptors to support receptor pharmacology, behavioral, and signaling experiments.
- Selective 5-HT2C receptor antagonist (high affinity).
- High purity (~98.0%).
- Molecular weight 649.08 g/mol.
- CAS number 187397-18-8 for unequivocal identification.
- Available in small preclinical quantities (for example, 10 mg).
- Product page includes datasheet and safety data sheet.
Medchemexpress LLC 2-(2-benzofuranyl)-2-imidazoline hydrochloride | 89196-95-2 | MFCD00672666 | >=98.0% | 222.67 g/mol | C11H11ClN2O | 1 ML
RX 801077 hydrochloride (2-(2-benzofuranyl)-2-imidazoline hydrochloride) is a selective imidazoline I2 receptor (I2R) agonist supplied for research use. It is available as a solid and as a ready-to-use 10 mM solution in DMSO (1 mL), and is commonly used in in vitro pharmacology and receptor-binding studies focused on inflammation and neuroprotection. Consult the safety data sheet for handling and storage.
- Selective imidazoline I2 receptor agonist.
- Available as solid powder and as a 10 mM solution in DMSO, 1 mL.
- High purity suitable for analytical and pharmacological studies.
- Molecular weight 222.67 g/mol; formula C11H11ClN2O.
- Intended for in vitro pharmacology, receptor binding, and neuroprotection research.
Medchemexpress LLC 5-Hydroxytryptamine creatinine sulfate monohydrate | 61-47-2 | 99.9% | 405.43 | 1 ML
5-Hydroxytryptamine creatinine sulfate monohydrate is an endogenous metabolite. This product is a 10 mM solution in 1 mL of DMSO, suitable for various research applications.
- Purity of 99.87%
- Endogenous metabolite
- Solution in DMSO
- For research use only
Medchemexpress LLC N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)-benzenesulfonamide monohydrochloride | 402713-81-9 | >98.0% | 482.8 g·mol⁻¹ | C18H21Cl2N3O4S · HCl | 25 MG
SB-399885 hydrochloride is a research compound that acts as a selective antagonist of the serotonin 5-HT6 receptor (CAS 402713-81-9). It is used in vitro and in vivo to study 5-HT6-mediated signaling and cognitive effects, and is supplied as the monohydrochloride salt to improve solubility for biological assays.
- 5-HT6 receptor antagonist activity for receptor pharmacology studies.
- Reported high purity for reliable experimental results.
- Monohydrochloride salt form improves solubility in aqueous media.
- Suitable for in vitro and in vivo neuroscience applications.
- Supplied in small research pack sizes for dose-response and pilot studies.
Medchemexpress LLC Benzamil hydrochloride | 161804-20-2 | 99.7% | 100 MG
Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na+/Ca2+ exchanger (NCX) inhibitor (IC50~100 nM). It is also a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3-mediated Ca2+-activated currents, with an IC50 of 1.1 μM.
- Na+/Ca2+ exchanger (NCX) inhibitor
- Non-selective Deg/epithelial sodium channels (ENaC) blocker
- Can potentiate myogenic vasoconstriction
- Inhibits TRPP3-mediated Ca2+-activated currents
Medchemexpress LLC 1-(2-Hydroxy-4,6-dimethoxyphenyl)-4-(piperazin-1-yl)butan-1-one dihydrochloride | 99.9% | 381.29 | 50 MG
Y13g dihydrochloride is a chemical compound supplied by MedChemExpress. It has a molecular weight of 381.29 and a purity of 99.89% as determined by LCMS. It appears as an off-white to light yellow solid and is stored at -20°C in sealed conditions away from moisture.
- Appears as an off-white to light yellow solid
- Purity of 99.89% verified by LCMS
- Consistent with ¹H NMR spectrum and LCMS analysis
- Recommended storage at -20°C in sealed conditions away from moisture
Medchemexpress LLC TPT-260 dihydrochloride | 2076-91-7 | 98.0% | C8H14Cl2N4S3 | 10MG
TPT-260 Dihydrochloride is a thiourea-derived small-molecule research compound supplied as a light yellow to yellow solid with high reported purity. It is used in preclinical biochemical and pharmacological studies where controlled solubility and defined storage stability are required.
- High purity: 98.0% ensuring reproducible results.
- Light yellow solid with defined appearance for easy identification.
- Well characterized solubility in common solvents (DMSO and water); ultrasonic assistance recommended.
- Clear storage guidance for stability in solid and solution states.
- Available in small pack sizes suitable for research-scale experiments.
Medchemexpress LLC (S)-1-(4-bromo-6-pyrimidinyl)-N-(2,4-dichlorobenzyl)-2-(pyrrolidin-1-yl)ethan-1-amine hydrochloride | 885104-09-6 | 99.9% | 438.58 g·mol⁻¹ | C15H16BrCl3N4 | 50 MG
LY2389575 hydrochloride is the hydrochloride salt of a small-molecule negative allosteric modulator of the metabotropic glutamate receptor 3 (mGlu3), intended for preclinical research. It is supplied as a solid powder with high purity and defined storage conditions for long-term stability.
- Negative allosteric modulator of mGlu3 for preclinical research
- High purity (99.9%) suitable for analytical and biological assays
- Solid powder form for convenient handling and formulation
- Defined storage stability: powder -20°C up to 3 years or 4°C up to 2 years
- Molecular weight 438.58 g·mol⁻¹ and formula C15H16BrCl3N4
![Medchemexpress LLC 2-Pyridinecarboxamide, N-[3-chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]- | 1246086-78-1 | C18H13Cl2N3O3S | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC 2-Pyridinecarboxamide, N-[3-chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]- | 1246086-78-1 | C18H13Cl2N3O3S | 1 ML
VU 0364439 is a mGlu4 positive allosteric modulator (PAM) with an EC50 of 19.8 nM. It demonstrates positive allosteric modulation of the human mGlu4 receptor, expressed in CHO cells, by potentiating glutamate-induced calcium mobilization. While showing better stability in human liver microsomes (HLM) with 63% remaining than rat liver microsomes (RLM) with 2% remaining, its pharmacokinetic properties are less than ideal, limiting its direct use as an in vivo tool.
- Acts as a mGlu4 positive allosteric modulator
- Has an EC50 of 19.8 nM
- Potentiates glutamate-induced calcium mobilization in human mGlu4 receptor
- Exhibits better stability in HLM (63% remaining) than RLM (2% remaining)
Medchemexpress LLC PD 128907 hydrochloride | 112960-16-4 | MFCD01529976 | 99.5% | 285.77 | C14H20ClNO3 | 25 MG
PD 128907 hydrochloride is a potent and selective dopamine D3 receptor agonist supplied as a solid biochemical reagent for life-science research. It is used in pharmacology and neurobiology to probe D3-mediated signaling and dopaminergic mechanisms, and is provided at high purity in small pack sizes for laboratory experiments.
- Potent D3 receptor agonist with low-nanomolar activity.
- High selectivity over D2 receptors for receptor-specific studies.
- High purity suitable for research applications.
- Solid form with white to light yellow appearance.
- Available in multiple small pack sizes for dosing flexibility.
- Recommended sealed storage away from moisture to preserve stability.
Medchemexpress LLC TAK-960 dihydrochloride | 99.2% | 634.52 | 5 MG
TAK-960 dihydrochloride is an orally available, selective inhibitor of polo-like kinase 1 (PLK1), with an IC50 of 0.8 nM. It also demonstrates inhibitory activities against PLK2 and PLK3, with IC50s of 16.9 and 50.2 nM, respectively. This compound inhibits the proliferation of multiple cancer cell lines and shows significant efficacy against various tumor xenografts.
- Orally available
- Selective inhibitor of polo-like kinase 1 (PLK1)
- Inhibits proliferation of multiple cancer cell lines
- Exhibits significant efficacy against various tumor xenografts
- Causes accumulation of G2-M cells
- Leads to G2/M cell cycle arrest
Medchemexpress LLC Benzenepropanoic acid, ß-(aminomethyl)-4-chloro-, hydrochloride (1:1) | 28311-31-1 | 99.8% | C10H13Cl2NO2 | 1 ML
Baclofen hydrochloride is a lipophilic derivative of γ-aminobutyric acid (GABA) and an orally active, selective metabotropic GABAB receptor (GABABR) agonist. It mimics the action of GABA, producing slow presynaptic inhibition through the GABAB receptor. This compound exhibits high blood-brain barrier penetrance, making it suitable for muscle spasticity research.
- Orally active, selective GABAB receptor agonist.
- Mimics GABA action for slow presynaptic inhibition.
- Exhibits high blood-brain barrier penetrance.
- Increases cell viability in huntingtin-expressing striatal cells.
- Enhances chymotrypsin-like proteasome activity.
- Ameliorates motor deficits in Huntington's disease animal models.
- Reduces neuronal intranuclear inclusions in animal models.
Medchemexpress LLC SKF-96365 hydrochlor 50mg
SKF-96365 hydrochloride is a potent TRP channel blocker and a store-operated Ca2 entry (SOCE) inhibitor SKF-96365 hydrochloride significantly inhibits hERG hKCNQ1/hKCNE1 hKir2 1 and hKv4 3 current and significantly prolongs the QTc interval in isolated guinea pig hearts SKF-96365 hydrochloride exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal cancer cells1]2]
Medchemexpress LLC Ly-272015 hydrochloride | 172895-15-7 | 99.5% | 372.89 | C21H25ClN2O2 | 25 MG
LY-272015 hydrochloride is the hydrochloride salt of LY-272015, an orally active and selective 5-HT2B receptor antagonist supplied as a high-purity solid for laboratory research. It is used to probe serotonergic signaling and downstream ERK2 phosphorylation in preclinical studies.
- Orally active, selective 5-HT2B receptor antagonist.
- Useful for research into serotonergic signaling and ERK2 phosphorylation.
- High purity (about 99.5%) for reliable experimental results.
- Off-white to light yellow solid, suitable for analytical handling.
- Stable when stored sealed at 4°C; in solvent: -80°C for 6 months, -20°C for 1 month.
- Available in small research quantities, including 25 MG.