Hydrochlorides
Medchemexpress LLC Kari 201 hydrochloride | 2376132-24-8 | 320.86 | 5 MG
KARI 201 hydrochloride is a selective, brain penetrant pan-competitive acid sphingomyelinase (ASM) inhibitor with an IC50 of 338.3 nM. It also acts as a ghrelin receptor agonist.
- Selective, brain penetrant pan-competitive acid sphingomyelinase (ASM) inhibitor
- Ghrelin receptor agonist
- Improves neuropathological features of Alzheimer's disease
Medchemexpress LLC VU 0240551 | 893990-34-6 | 99.7% | 342.44 | 100 MG
VU 0240551 is a potent neuronal K-Cl cotransporter KCC2 inhibitor (IC50=560 nM) that is selective versus NKCC1. It also inhibits hERG and L-type Ca2+ channels, making it a valuable tool in neuroscience research. This compound attenuates GABA-induced hyperpolarization of P cells, produces a positive shift in the P cell GABA reversal potential, and enhances P cell synaptic transmission.
- Potent neuronal K-Cl cotransporter KCC2 inhibitor
- Selective inhibition over NKCC1
- Inhibits hERG and L-type Ca2+ channels
- Attenuates GABA-induced hyperpolarization of P cells
- Enhances P cell synaptic transmission
Medchemexpress LLC Duloxetine hydrochloride | 136434-34-9 | 99.97% | 1 ML
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depressive disorder and generalized anxiety disorder (GAD). This product is for research use only and not sold to patients.
- Serotonin-norepinephrine reuptake inhibitor (SNRI)
- Used for major depressive disorder and generalized anxiety disorder
- For research use only
Medchemexpress LLC HY-107994 500mg Medchemexpress, Aminooxyacetic acid hemihydrochloride CAS:2921-14-4 Purity:>98%
Medchemexpress, HY-107994 500mg Aminooxyacetic acid hemiHCl CAS:2921-14-4 Aminooxyacetic acid hemihydrochloride is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABA degradating enzyme GABA-T. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Amastatin hydrochlor 1mg | 100938-10-1 | 511.01 g/mol | C21H39ClN4O8 | 1 MG
Amastatin hydrochloride is a research-grade, slow, tight-binding competitive inhibitor of aminopeptidases, used in enzymology and biochemical assays to probe aminopeptidase activity. It is supplied as the hydrochloride salt and is provided in small quantities for laboratory research.
- Inhibits multiple aminopeptidases with low-nanomolar Ki values.
- Suitable for enzymology and biochemical research applications.
- Provided as hydrochloride salt for improved handling and solubility.
- High purity (98.0%).
- Molecular weight 511.01 g/mol.
- Available in small pack sizes (1 mg, 5 mg, 10 mg, 50 mg).
Medchemexpress LLC Tirofiban | 144494-65-5 | 440.60 | 5 MG
Tirofiban is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist. It inhibits fibrinogen binding to this receptor, providing antithrombotic activity. Tirofiban induces proliferation and migration on endothelial cells by stimulating VEGF production. It can significantly reduce myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area.
- Selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist
- Inhibits fibrinogen binding
- Provides antithrombotic activity
- Induces endothelial cell proliferation and migration
- Stimulates vascular endothelial growth factor (VEGF) production
- Reduces myocardial no-reflow
- Alleviates myocardial microvascular structural and endothelial dysfunction
- Targets integrin
- Affects cytoskeleton pathway
Medchemexpress LLC Piperoxan hydrochloride | 135-87-5 | MFCD00079224 | 99.7% | 269.77 | C14H20ClNO2 | 5 MG
Piperoxan hydrochloride is a small-molecule research reagent described as an α2 adrenoceptor antagonist and a first-generation antihistamine. Supplied as the hydrochloride salt (CAS 135-87-5), it is used in pharmacology and receptor-binding studies to probe adrenergic and histaminergic mechanisms.
- High purity research-grade small molecule (molecular weight 269.77).
- Acts as an α2 adrenoceptor antagonist for receptor pharmacology studies.
- Exhibits first-generation antihistamine properties relevant to histamine assays.
- Available in milligram-scale quantities suitable for in vitro research.
- Provided with SDS and COA documentation for handling and quality assurance.
Medchemexpress LLC 3-Pyridylacetic acid hydrochloride | 6419-36-9 | 173.60 | 1 ML
3-Pyridylacetic acid hydrochloride is a high homolog of nicotinic acid and a decomposition product of nicotine (and other tobacco alkaloids). It can be used to synthesize anti-inflammatory agents or as a precursor for the preparation of herbicides.
- Used to synthesize anti-inflammatory agents
- Precursor for the preparation of herbicides
Medchemexpress LLC Prodipine hydrochloride | 31314-39-3 | 99.8% | 315.9 g/mol | C20H26ClN | 10 MG
Prodipine hydrochloride is a diphenyl-phosphonate derivative used as a research DPP-IV inhibitor. It has been characterized in vitro and in vivo for inhibition of dipeptidyl peptidase IV and is supplied for laboratory research use.
- Inhibits dipeptidyl peptidase IV (DPP-IV) in vitro and in vivo.
- Reported IC50 values: purified rabbit DPP-IV 4.5 μM; rabbit plasma DPP-IV 30 μM.
- High reported purity (99.8%).
- Molecular formula C20H26ClN; molecular weight 315.9 g/mol.
- Intended for biochemical and pharmacological research use only.
- Available in small research pack sizes suitable for assay work.
![Medchemexpress LLC Acetamide, N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]- | 893990-34-6 | MFCD05957363 | 99.7% | 342.44 | C16H14N4OS2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000289016.png-250.jpg)
Medchemexpress LLC Acetamide, N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]- | 893990-34-6 | MFCD05957363 | 99.7% | 342.44 | C16H14N4OS2 | 10 MG
VU 0240551 is a small-molecule research compound that acts as a potent neuronal K+-Cl- cotransporter 2 (KCC2) inhibitor and is used in in vitro pharmacology and preclinical studies. It shows submicromolar activity at KCC2 and selectivity versus NKCC1.
- Potent KCC2 inhibitor (IC50 ≈ 560 nM).
- Selective versus NKCC1 (IC50 > 50 μM).
- High purity (99.7%).
- Molecular weight 342.44; formula C16H14N4OS2.
- White to off-white solid with high solubility in DMSO (≥ 50 mg/mL).
- Recommended storage: powder -20 °C (long-term) or 4 °C (shorter term); solvent storage at -80 °C.
- Supplied in small pack sizes suitable for research (5 mg-100 mg).
Sigma Aldrich Fine Chemicals Biosciences Procaine hydrochloride >=97% | 51-05-8 | MFCD00013000 | 100G
Procaine hydrochloride >=97% | Purity: >=97% | Mol Wt: 272.77 | 51-05-8 | MFCD00013000 | 100G
Medchemexpress LLC Ambroxol (hydrochloride) | 23828-92-4 | 99.9% | 25 MG
Ambroxol hydrochloride is an active metabolite of Bromhexine, known for its potent expectorant effects. It acts as a glucocerebrosidase (GCase) chaperone, enhancing GCase activity. It induces lung autophagy and is being researched for potential use in Parkinson's disease and neuronopathic Gaucher disease.
- Potent expectorant effects.
- Acts as a glucocerebrosidase (GCase) chaperone.
- Increases glucocerebrosidase activity.
- Induces lung autophagy.
- Potential for research in Parkinson's disease.
- Potential for research in neuronopathic Gaucher disease.
Sigma Aldrich Fine Chemicals Biosciences 4-Methylmorpholine BioXtra, suitable for protein sequencing, >=99.5% (GC) | 109-02-4 | MFCD00006175 | 100ML
4-Methylmorpholine BioXtra, suitable for protein sequencing, >=99.5% (GC) | Purity: >=99.5% (GC) | Mol Wt: 101.15 | 109-02-4 | MFCD00006175 | 100ML