Furans
Medchemexpress LLC Ganoderal A | 104700-98-3 | 5 MG
Ganoderal A is an oxygenated sterol derived from *Ganoderma lucidum*. It functions as a cholesterol synthesis inhibitor and is intended for research use only.
- Oxygenated sterol derived from *Ganoderma lucidum*.
- Functions as a cholesterol synthesis inhibitor.
- Purity: 97.54%.
Medchemexpress LLC Paederosidic acid | 18842-98-3 | MFCD28124366 | 10 MG
Paederosidic acid, isolated from P. scandens, is a chemical compound exhibiting anticancer and anti-inflammation activities. It primarily acts by inducing mitochondria-mediated apoptosis in lung cancer cells.
- Inhibits lung cancer cells by inducing mitochondria-mediated apoptosis.
- Shows effects on NCI-H1650, HCC827, and A549 cells.
- Up-regulates caspase-3, caspase-8, caspase-9, Bid, Bax.
- Down-regulates Bcl-2.
- Stimulates Cyto-C release from mitochondria.
Medchemexpress LLC Dma-135 hydrochloride | 2237925-62-9 | 98.0% | C16H18ClN7O | 100 MG
DMA-135 hydrochloride inhibits enterovirus 71 (EV71) IRES-dependent translation and replication. It binds to enterovirus 71 (EV71) SLII domain with moderately high affinity (KD= 520 nM) and has no significant toxicity in cell-based studies.
- Inhibits enterovirus 71 (EV71) IRES-dependent translation and replication
- Binds to EV71 SLII domain with moderate affinity (KD= 520 nM)
- No significant toxicity in cell-based studies
- Induces conformational changes in RNA structure
- Stabilizes DMA135-RNA-AUF1 ternary complex
- Inhibits EV71 with an IC50 of 7.54 μM
Apexbio Technology LLC 5-hydroxymethyl-2-furaldehyde 67-47-0 20mg
5-hydroxymethyl-2-furaldehyde (67-47-0) is a small-molecule inhibitor targeting yeast metabolic pathways It is designed to suppress yeast growth and fermentation thereby modulating microbial metabolism 5-hydroxymethyl-2-furaldehyde exerts its biological activity primarily through inhibition of yeast metabolic processes In cell-based studies 5-hydroxymethyl-2-furaldehyde demonstrates inhibitory activity with an IC50 value of approximately 2 5 5 0 mM depending on yeast strain and experimental conditions Based on these pharmacological properties 5-hydroxymethyl-2-furaldehyde holds research potential in studies of yeast biology fermentation inhibition mechanisms and microbial metabolism
![Medchemexpress LLC β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl, 6-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate] | 105471-98-5 | MFCD22125003 | 99.9% | 478.45 | C23H26O11 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000295724.png-250.jpg)
Medchemexpress LLC β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl, 6-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate] | 105471-98-5 | MFCD22125003 | 99.9% | 478.45 | C23H26O11 | 10 MG
Calceolarioside B is a naturally occurring phenylethanoid glycoside supplied as a research-grade small-molecule. It is reported to inhibit RLAR activity and has shown antiviral, immunomodulatory, and anticancer activity in in vitro assays. Use is limited to laboratory research only.
- Phenylethanoid glycoside chemical class with defined structure and formula.
- Reported RLAR inhibitor (IC50 ≈ 23.99 μM) useful for enzyme assays.
- Shown to reduce IL-6 levels and inhibit viral entry in vitro.
- High reported purity suitable for biochemical and cell-based studies.
- Supplied in small research pack sizes for laboratory use.
![Medchemexpress LLC 5-cyclohexyl-3,3-dimethyl-1-[4-[2-(oxan-4-ylamino)ethylamino]phenyl]-2-oxo-1,4-benzodiazepine | 2376334-75-5 | 99.4% | 513.67 g/mol | C31H39N5O2 | 50MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000238159.png-250.jpg)
Medchemexpress LLC 5-cyclohexyl-3,3-dimethyl-1-[4-[2-(oxan-4-ylamino)ethylamino]phenyl]-2-oxo-1,4-benzodiazepine | 2376334-75-5 | 99.4% | 513.67 g/mol | C31H39N5O2 | 50MG
This small-molecule parathyroid hormone receptor 1 (PTHR1) antagonist is a potent, orally bioavailable compound (IC50 = 90 nM) intended for research use. It is supplied as a light yellow to yellow solid with high reported purity and defined physicochemical properties suitable for in vitro and in vivo preclinical studies.
- Potent PTHR1 antagonist with IC50 of 90 nM.
- Orally bioavailable in preclinical models.
- High purity (99.4%) and solid form, light yellow to yellow.
- Molecular formula C31H39N5O2 and molecular weight 513.67 g/mol.
- Multiple pack sizes available to support assay scale-up.
- Supplied for research use only.
Medchemexpress LLC Bv02 | 292870-53-2 | MFCD00356631 | 99.8% | 377.36 g/mol | C20H15N3O5 | 10 MG
BV02 is a small-molecule inhibitor of 14-3-3 protein-protein interactions used in preclinical research to study apoptosis, autophagy, Akt signaling, and host-pathogen responses. It is provided for in vitro experiments in solid form and as a DMSO solution.
- High chemical purity (≈99.8%).
- Well-defined molecular formula C20H15N3O5 and molecular weight 377.36 g/mol.
- Indexed by CAS number 292870-53-2 for unambiguous identification.
- Available in multiple solid sizes and as a 10 mM solution in DMSO for assay readiness.
- Reported to modulate PARP and caspase-3 cleavage and to affect Akt signaling in cell studies.
- Supplied for research use only; not for human or veterinary use.
Medchemexpress LLC 7-TFA-ap-7-Deaza-dA | 178420-75-2 | 98.8% | 399.32 | 100 MG
7-TFA-ap-7-Deaza-dA is a modified nucleoside and a click chemistry reagent. It is utilized in the synthesis of deoxyribonucleic acid or nucleic acid. Featuring an alkyne group, this compound is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. It is intended for laboratory use and substance manufacturing, strictly for research purposes.
- Modified nucleoside
- Click chemistry reagent
- Contains an alkyne group for CuAAc reactions
- Supports DNA and nucleic acid synthesis
- For laboratory chemicals and substance manufacturing
- For research use only
![Medchemexpress LLC 4-[2-(cyclopropylmethoxy)-5-(methylsulfonyl)phenyl]-2-methyl-1(2H)-isoquinolinone | 1706738-98-8 | >98.0% | C21H21NO4S | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000259395.png-250.jpg)
Medchemexpress LLC 4-[2-(cyclopropylmethoxy)-5-(methylsulfonyl)phenyl]-2-methyl-1(2H)-isoquinolinone | 1706738-98-8 | >98.0% | C21H21NO4S | 10MG
Trotabresib is an oral, potent, reversible small-molecule inhibitor of bromodomain and extra-terminal (BET) proteins. It is used in preclinical and clinical oncology research for advanced solid tumors and glioma and is supplied as a research-grade solid for translational studies.
- Oral, reversible BET inhibitor suitable for epigenetic research.
- Demonstrates antitumor activity in cell lines and xenograft models.
- High purity (typically >98%) for reliable experimental results.
- Solid powder form, soluble in common organic solvents such as DMSO.
- Applicable to preclinical and clinical translational studies in oncology.
Medchemexpress LLC 1-aminohydantoin hydrochloride | 2827-56-7 | MFCD02181047 | 98.0% | 151.55 | C3H6ClN3O2 | 250mg
1-Aminohydantoin hydrochloride (Standard) is the analytical standard of 1-Aminohydantoin hydrochloride (HY-Y0469) This product is intended for research and analytical applications 1-Aminohydantoin hydrochloride is a major metabolite of Nitrofurantoin (HY-A0090) in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat milk et al 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of 1-Aminohydantoin hydrochloride before detection[1][2]
Medchemexpress LLC Ethynodiol diacetate | 297-76-7 | MFCD00083326 | 99.85% | 1 G
Ethynodiol diacetate is a click chemistry reagent that contains an Alkyne group. It can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It is for research use only and not sold to patients.
- Click chemistry reagent
- Contains an Alkyne group
- Can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
Medchemexpress LLC Trotabresib | 1706738-98-8 | 99.7% | 383.46 | 100 MG
Trotabresib is a reversible and orally active BET inhibitor used in the study of advanced solid tumors. It inhibits the proliferation of diffuse midline glioma (DMG) cells and shows stronger antitumor activity against H3K27M mutant DMG cells than DMG wildtype.
- Reversible and orally active BET inhibitor
- Applied in studies for advanced solid tumors
- Inhibits proliferation of diffuse midline glioma (DMG) cells
- Shows stronger antitumor activity against H3K27M mutant DMG cells than DMG wildtype
Medchemexpress LLC FIDAS-5 | 1391934-98-7 | 98.5% | 261.72 | 50 MG
FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. It effectively competes against S-adenosylmethionine (SAM) for MAT2A binding and exhibits anticancer activities.
- Potent and orally active MAT2A inhibitor
- Effectively competes against S-adenosylmethionine (SAM)
- Exhibits anticancer activities
- Store powder at -20°C for 3 years or 4°C for 2 years
- Compound is unstable in solutions, freshly prepared is recommended
Medchemexpress LLC JNJ-1661010 (Takeda-25) | 681136-29-8 | 5 MG
JNJ-1661010, also known as Takeda-25, is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH). It exhibits IC50 values of 34 nM for rat FAAH and 33 nM for human FAAH. This compound is capable of crossing the blood-brain barrier and is utilized as a broad-spectrum analgesic.
- Potent and selective FAAH inhibitor
- Crosses the blood-brain barrier
- Acts as a broad-spectrum analgesic
- Shows apparent inhibition of human FAAH in CHO-K1 cells with an IC50 of 11 nM
- Diminishes thermal hyperalgesia in inflammatory rat models
![Medchemexpress LLC 2-[(2-carboxyphenyl)amino]-4-chlorobenzoic acid | 63329-53-3 | MFCD00866065 | 99.4% | 291.68 g/mol | C14H10ClNO4 | 50MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000237302.png-250.jpg)
Medchemexpress LLC 2-[(2-carboxyphenyl)amino]-4-chlorobenzoic acid | 63329-53-3 | MFCD00866065 | 99.4% | 291.68 g/mol | C14H10ClNO4 | 50MG
Lobenzarit is a small-molecule immunomodulator used in preclinical research that has reported anti-oxidative and anti-inflammatory properties. It is supplied as a high-purity research reagent (CAS 63329-53-3) and is used in vitro and in vivo to study immune modulation and anti-arthritic effects.
- High purity suitable for research use.
- Reported immunomodulatory and anti-oxidative activity.
- Available in multiple small-scale sizes for preclinical studies.
- Stable when stored under recommended conditions (powder and in solvent).
- Molecular formula C14H10ClNO4; molecular weight 291.68 g/mol.