Furans
Medchemexpress LLC CX-6258 (hydrochloride) | 1353859-00-3 | 99.0% | 498.40 | 50 MG
CX-6258 hydrochloride is a potent and kinase-selective pan-Pim kinases inhibitor. It effectively inhibits Pim-1, Pim-2, and Pim-3, causing dose-dependent inhibition of pro-survival proteins like Bad and 4E-BP1. In vitro studies show it diminishes ectopic NKX3.1 levels, while in vivo, it exhibits robust efficacy in Pim kinases driven tumor models, demonstrating significant tumor growth inhibition.
- Potent and kinase-selective pan-Pim kinases inhibitor.
- Inhibits phosphorylation of pro-survival proteins.
- Diminishes steady-state levels of ectopic NKX3.1 in PC3 cells.
- Exhibits robust efficacy in Pim kinases driven tumor models in vivo.
- For research use only.
Medchemexpress LLC Azimilide | 149908-53-2 | 99.0% | 457.95 | 5 MG
Azimilide is a class III antiarrhythmic agent that blocks potassium channels in the heart. It is a dual blocker of IKs and IKr potassium channels. It also blocks HERG channels, and inhibits L-type calcium current (ICa) and sodium current (INa). It can be used for the study of atrial fibrillation and ventricular fibrillation.
- Class III antiarrhythmic agent
- Dual blocker of IKs and IKr potassium channels
- Blocks HERG channels
- Inhibits L-type calcium current (ICa)
- Inhibits sodium current (INa)
- Can be used for the study of atrial fibrillation and ventricular fibrillation
- Significantly reduces the occurrence of ventricular tachycardia (VT) induced by electrical stimulation (PES) in dogs
- Prolongs the effective refractory period of the ventricle and the QTc interval
- Provides significant protection against ischemia-induced ventricular fibrillation and improves survival rates
Medchemexpress LLC Dantrolene sodium hemiheptahydrate | 24868-20-0 | MFCD07357270 | 99.8% | 399.31 g·mol⁻¹ | C14H9N4NaO5 · 3.5H2O | 500MG
Dantrolene sodium hemiheptahydrate is the sodium salt hydrate form of dantrolene, a direct-acting skeletal muscle relaxant and ryanodine receptor (RyR) inhibitor used as a research reagent in studies of muscle spasm, malignant hyperthermia, and calcium-related pathophysiology. Supplied in multiple pack sizes for laboratory use.
- High purity (99.8%).
- Inhibits RyR-mediated Ca2+ release for calcium signaling studies.
- Supplied as the hemiheptahydrate crystalline form.
- Molecular weight 399.31 g·mol⁻¹.
- Available in multiple pack sizes, including 500 mg.
- Intended for laboratory research use only.
eMolecules Medchem Express / CX-6258 (hydrochloride hydrate) / 5mg / 415688005 / HY-18095A / / 1353858-99-7 / MFCD26142938 / 516.420 / C26H27Cl2N3O4
Medchem Express / CX-6258 (hydrochloride hydrate) / 5mg / 415688005 / HY-18095A / / 1353858-99-7 / MFCD26142938 / 516.420 / C26H27Cl2N3O4
Medchemexpress LLC Dantrolene | 7261-97-4 | MFCD00867709 | 98.4% | 314.25 g/mol | C14H10N4O5 | 500MG
Dantrolene is a small-molecule ryanodine receptor antagonist used as a direct-acting skeletal muscle relaxant in research. It is supplied as a solid powder with a reported purity of 98.38% and is offered in multiple pack sizes, including a 500 mg vial. Manufacturer documentation includes a datasheet, certificate of analysis, and safety data sheet to support experimental use and handling.
Medchemexpress LLC Dantrolene | 7261-97-4 | MFCD00867709 | 98.4% | 314.25 g/mol | C14H10N4O5 | 10MM 1ML
Dantrolene is a ryanodine receptor antagonist and skeletal muscle relaxant offered as a ready-to-use 10 mM solution in DMSO (1 mL) and as solid pack sizes. The product is intended for use as a reference compound in in vitro pharmacology, biochemical assays, and RyR modulation studies; CAS 7261-97-4 and high assay purity support research applications.
- Ready-to-use 10 mM solution in DMSO (1 mL) for in vitro assays.
- Also available as solid in multiple pack sizes for formulation flexibility.
- High purity (98.4%) confirmed by RP-HPLC.
- Suitable as a ryanodine receptor antagonist and muscle relaxant reference.
- Supplied with datasheet and HPLC purity report for quality assurance.
Selleck Chemical LLC Dantrolene sodium
Dantrolene sodium(F 440) acts as a postsynaptic muscle relaxant by inhibiting Ca2 ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors
Medchemexpress LLC Dantrolene-13C3 | 1185234-99-4 | 99.9% | 314.25 g/mol | C11(13C)3H10N4O5 | 1MG
Dantrolene-13C3 is a stable isotope-labeled analogue of dantrolene provided for research use as an internal standard or tracer in analytical and metabolic studies. The compound contains three 13C labels, has a molecular weight of 317.23 g/mol, and is typically supplied in milligram-scale quantities for analytical applications.
- Stable isotope labeled with three 13C atoms.
- High chemical purity (HPLC): 99.87%.
- High isotopic enrichment: 99.1%.
- Molecular weight: 317.23 g/mol.
- CAS number: 1185234-99-4.
- Supplied in milligram quantities suitable for analytical standards.
Medchemexpress LLC Dantrolene | 7261-97-4 | MFCD00867709 | 98.4% | 314.26 g/mol | C14H10N4O5 | 10MG
Dantrolene is a research-grade skeletal muscle relaxant and ryanodine receptor (RyR) inhibitor used to study calcium homeostasis, malignant hyperthermia, muscle spasm, and related neurological or ischemic conditions. It acts as a non-competitive glutathione reductase inhibitor (reported Ki 111.6 μM; IC50 52.3 μM) and inhibits Ca2+ release from RyR1 and RyR3, making it useful for biochemical and cell-based studies.
- Direct RyR1 and RyR3 calcium-release inhibitor.
- Used in research on malignant hyperthermia and muscle spasm.
- Non-competitive glutathione reductase inhibitor with reported Ki/IC50 values.
- Available in solid and solution formats suitable for assays.
- High reported purity (~98.4%).
- Molecular formula C14H10N4O5; molecular weight ~314.26 g/mol.
Medchemexpress LLC Methyl 2-furoate | 611-13-2 | MFCD00003236 | 99.9% | 126.11 g/mol | C6H6O3 | 50g
Methyl 2-furoate (Methyl furan-2-carboxylate) can be used to synthesize cis-fused 5-oxofuro[2 3-b]furans Methyl 2-furoate is also used in the preparation of sesquiterpene lactones[1]
Cayman Chemical Mometason Furoate-d3 500ug
An internal standard for the quantification of mometasone furoate by GC- or LC-MS
Accela Chembio Inc Diethyl 3 | 4-furandicarboxylate | 5g | 30614-77-8 | MFCD00005349 | 95+% | D: 1.14 | Shelf Life: 1620 Days | Light Sensitive
Diethyl 3 | 4-furandicarboxylate | 5g | 30614-77-8 | MFCD00005349 | 95+% | D: 1.14 | Shelf Life: 1620 Days | Light Sensitive
eMolecules 7-Bromo-5-nitrobenzofuran-2-carboxylic acid | 286836-15-5 | | 1g
Apollo Scientific | 7-Bromo-5-nitrobenzofuran-2-carboxylic acid | 1g | 562429771 | OR54655 | | 286836-15-5 | | 286.037 | C9H4BrNO5
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McKesson General Medical Mometasone Furoate 0.1% Ointment Tube 45 Gram
Mometasone Furoate 0.1% Ointment Tube 45 Gram