Furans
Medchemexpress LLC BMS-911172 5mg | 1644248-18-9 | 5 MG
BMS-911172 is a small-molecule inhibitor of adaptor protein 2-associated kinase 1 (AAK1) supplied as a solid for laboratory research. It is brain-penetrant and reported to have low-nanomolar potency in biochemical and cellular assays (reported IC50 values ≈12-35 nM). For research use only.
- Potent AAK1 inhibitor with low-nanomolar activity.
- Brain-penetrant small molecule suitable for CNS-targeted studies.
- High purity (~99.5%) solid form for analytical and biological work.
- Supplied in a small quantity suitable for pilot or mechanistic studies.
- Intended for research use only; not for human or clinical use.
![Medchemexpress LLC 2-(2-fluorophenyl)-N-hydroxy-2-[4-[5-(trifluoromethyl)pyrimidin-2-yl]phenyl]acetamide | 1629729-98-1 | 98.1% | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000234654.png-250.jpg)
Medchemexpress LLC 2-(2-fluorophenyl)-N-hydroxy-2-[4-[5-(trifluoromethyl)pyrimidin-2-yl]phenyl]acetamide | 1629729-98-1 | 98.1% | 50 MG
CHDI-390576 is a potent, cell-permeable, CNS-penetrant small-molecule inhibitor selective for class IIa histone deacetylases (HDAC4, HDAC5, HDAC7, HDAC9). It is provided as a high-purity research compound for biochemical and cellular studies of HDAC function and selectivity.
- Low-nanomolar inhibitory activity against class IIa HDAC isoforms (reported IC50s: HDAC4 54 nM, HDAC5 60 nM, HDAC7 31 nM, HDAC9 50 nM).
- High selectivity against class I HDACs and over HDAC8 and HDAC6.
- CNS penetrant and cell permeable for central nervous system research.
- High purity suitable for biochemical and cellular assays.
- Molecular formula C19H13F4N3O2; molecular weight 391.32.
Medchemexpress LLC Gunagratinib | 2211082-53-8 | 98.5% | C22H25N5O4 | 10MG
Gunagratinib is a research small molecule that irreversibly and covalently inhibits fibroblast growth factor receptors (FGFR). It is orally active in preclinical models and is used in cancer research and biochemical studies; the molecule also contains an alkyne handle that allows copper-catalyzed azide-alkyne cycloaddition (click chemistry) applications.
Medchemexpress LLC TCS PrP Inhibitor 13 25mg | 34320-83-7 | 25MG
TCS PrP Inhibitor 13 an antiprion agent is a cellular prion protein (PrPC) inhibitor TCS PrP Inhibitor 13 as a protease-resistant form of prion protein (PrP-res) accumulation inhibitor shows an IC50 value of 3 nM in both ScN2a and F3 cell lines TCS PrP Inhibitor 13 induces Schwannoma cells apoptosis[1
Medchemexpress LLC Modoflaner | 1331922-53-2 | Not found | 98.3% | C23H10F12IN3O2 | 10MG
Modoflaner is an isophenylamide insecticide research compound that may act through allosteric regulation of gamma-aminobutyric acid (GABA)-gated chloride channels. It is supplied as a white to off-white solid with reported high purity and is intended for research use only.
- Isophenylamide insecticide acting via allosteric modulation of GABA-gated chloride channels.
- Supplied as a white to off-white solid suitable for analytical and biological research.
- High reported purity (≈98.3%) supports assay and screening applications.
- Recommended storage conditions available for solid and solution to preserve stability.
- Available in small research pack sizes for laboratory use.
Medchemexpress LLC Nitrofurantoin-13c3 | 1217226-46-4 | C₅¹³C₃H₆N₄O₅ | 1 MG
Nitrofurantoin-13C3 is the 13C labeled Nitrofurantoin. Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. It acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes (carbon) for quantitation during drug development.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Lycoramine | 21133-52-8 | 99.8% | 289.37 g/mol | C17H23NO3 | 10 MG
Lycoramine is a dihydro-derivative of galanthamine isolated from Lycoris radiata. It functions as a potent acetylcholinesterase (AChE) inhibitor and is supplied for research use in biochemical and pharmacological studies. Refer to the manufacturer's documentation for COA and SDS.
- Potent acetylcholinesterase inhibitor used in in vitro assays.
- Available as a solid powder suitable for solution preparation.
- High purity (~99.8%), with certificate of analysis available.
- Applicable to neuroscience and cholinergic pathway research.
- Documented chemical identifiers: CAS 21133-52-8; formula C17H23NO3.
Medchemexpress LLC JNJ-55308942 | 2166558-11-6 | 99.9% | 425.32 | C17H12F5N7O | 5MG
JNJ-55308942 is a selective, brain-penetrant P2X7 receptor antagonist supplied for research use. It shows high affinity for human and rat P2X7 channels and includes solubility and formulation guidance to support both in vitro and in vivo studies.
- Selective P2X7 antagonist with hP2X7 IC50 = 10 nM and rP2X7 IC50 = 15 nM.
- Brain-penetrant, suitable for central nervous system studies.
- Molecular formula C17H12F5N7O; molecular weight 425.32.
- High purity (≈99.9%).
- Soluble in DMSO (100 mg/mL); in vivo formulations ≥4 mg/mL reported.
- Supplied in small milligram pack sizes for research applications.
Medchemexpress LLC L-proline, L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl (diacetate) | 00-00-0 | 99.9% | 871.98 | C37H65N11O13 | 10 MG
Selank diacetate is a synthetic peptide derived from tuftsin with reported anxiolytic, nootropic, antidepressant, and antistress activity. It is supplied as a white to off-white solid for laboratory research use only, with documented molecular and purity data to support experimental use. Use appropriate laboratory safety practices and consult the SDS and COA prior to handling.
- High purity suitable for research applications.
- Known amino acid sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro.
- Supplied as a white to off-white solid.
- High solubility in water with sonication recommended.
- COA and SDS available for quality and safety information.
Medchemexpress LLC BV02 | 292870-53-2 | MFCD00356631 | 99.8% | 377.36 g/mol | C20H15N3O5 | 5 MG
BV02 is a small-molecule 14-3-3 protein-protein interaction inhibitor provided as a white to off-white solid for research use. It has been reported to induce apoptosis and autophagy and to display antibacterial activity in preclinical studies. The product is supplied with stability guidelines for powder and solution storage.
Apexbio Technology LLC Terlipressin diacetate 1884420-36-3 25mg
Terlipressin diacetate (CAS 1884420-36-3) is a synthetic analogue of vasopressin classified as a vasopressin receptor agonist It exhibits high selectivity for V1 receptors localized on vascular smooth muscle where it induces pronounced vasoconstriction by activating the phospholipase C inositol 1 4 5-trisphosphate (IP3) signaling pathway This leads to increased vascular resistance and elevated blood pressure Terlipressin diacetate is widely utilized in biomedical research investigating mechanisms of vascular tone regulation hemodynamic response in portal hypertension and pathophysiology of conditions such as variceal bleeding and hepatorenal syndrome
eMolecules 1260667-24-0 | 3-ETHYNYLTETRAHYDRO-2H-PYRAN | AstaTech | MFCD18250569 | 110.156 | C7H10O | 95.000 | C#CC1CCCOC1 | 1g | 391060138
3-ETHYNYLTETRAHYDRO-2H-PYRAN | AstaTech | 1260667-24-0 | MFCD18250569 | 110.156 | C7H10O | 95.000 | C#CC1CCCOC1 | 1g | 391060138
Medchemexpress LLC Dma-135 hydrochloride | 2237925-62-9 | 98.0% | C16H18ClN7O | 100 MG
DMA-135 hydrochloride inhibits enterovirus 71 (EV71) IRES-dependent translation and replication. It binds to enterovirus 71 (EV71) SLII domain with moderately high affinity (KD= 520 nM) and has no significant toxicity in cell-based studies.
- Inhibits enterovirus 71 (EV71) IRES-dependent translation and replication
- Binds to EV71 SLII domain with moderate affinity (KD= 520 nM)
- No significant toxicity in cell-based studies
- Induces conformational changes in RNA structure
- Stabilizes DMA135-RNA-AUF1 ternary complex
- Inhibits EV71 with an IC50 of 7.54 μM
Medchemexpress LLC Trovafloxacin mesylate | 147059-75-4 | MFCD00913361 | 512.46 g·mol-1 | C21H19F3N4O6S | 5 MG
Trovafloxacin mesylate is a fluoroquinolone-class antibiotic supplied as the mesylate salt for research use. It is intended for laboratory studies involving antimicrobial testing and investigations of DNA gyrase and topoisomerase IV inhibition.
- broad-spectrum fluoroquinolone antibiotic for research applications.
- CAS number 147059-75-4 for unambiguous identification.
- molecular formula C21H19F3N4O6S and molecular weight 512.46 g·mol-1.
- soluble in DMSO (≈116.67 mg/mL) and water (≈20 mg/mL) with ultrasonic assistance.
- formulatable for in vivo use at ≥2.08 mg/mL in recommended vehicle systems.
- available in small pack sizes suitable for laboratory experiments (1 mg, 5 mg, 10 mg).
![Medchemexpress LLC 4-[2-(cyclopropylmethoxy)-5-(methylsulfonyl)phenyl]-2-methyl-1(2H)-isoquinolinone | 1706738-98-8 | >98.0% | C21H21NO4S | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000259395.png-250.jpg)
Medchemexpress LLC 4-[2-(cyclopropylmethoxy)-5-(methylsulfonyl)phenyl]-2-methyl-1(2H)-isoquinolinone | 1706738-98-8 | >98.0% | C21H21NO4S | 10MG
Trotabresib is an oral, potent, reversible small-molecule inhibitor of bromodomain and extra-terminal (BET) proteins. It is used in preclinical and clinical oncology research for advanced solid tumors and glioma and is supplied as a research-grade solid for translational studies.
- Oral, reversible BET inhibitor suitable for epigenetic research.
- Demonstrates antitumor activity in cell lines and xenograft models.
- High purity (typically >98%) for reliable experimental results.
- Solid powder form, soluble in common organic solvents such as DMSO.
- Applicable to preclinical and clinical translational studies in oncology.