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Filtered Search Results
Medchemexpress LLC Sisunatovir hydrochloride | 1903763-83-6 | 98.6% | 482.90 g/mol | C23H23ClF4N4O | 5MG
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Sisunatovir hydrochloride is the hydrochloride salt of sisunatovir (RV521), an orally active respiratory syncytial virus (RSV) fusion protein inhibitor supplied as a research-grade solid for in vitro and in vivo antiviral studies. It has defined molecular properties and high analytical purity appropriate for pharmacology and virology research.
- Potent RSV fusion inhibitor for antiviral research.
- Provided as a hydrochloride salt in solid powder form.
- High purity suitable for in vitro and in vivo studies.
- Well characterized molecular weight and chemical formula.
- Available in small research-scale quantities for assay use.
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Apexbio Technology LLC 5-Methoxytryptamine 608-07-1 500mg
5-Methoxytryptamine (CAS 608-07-1) also known as Mexamine or Methoxytryptamine is a synthetic derivative of tryptamine It acts as a full agonist at multiple serotonin receptor subtypes including 5-HT1 5-HT2 5-HT4 5-HT6 and 5-HT7 Through these interactions 5-Methoxytryptamine modulates serotonergic signaling pathways making it a valuable tool for studying serotonin-mediated physiological and neuropharmacological processes This compound is commonly utilized in research exploring serotonergic receptor function neural signaling and associated behavioral or biochemical outcomes
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![Medchemexpress LLC 1,2-benzisoselenazol-3(2H)-one, 2-[3-(trifluoromethyl)phenyl]- | 2570461-66-2 | 99.4% | 342.17 g·mol⁻¹ | C14H8F3NOSe | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000221197.png-250.jpg)
Medchemexpress LLC 1,2-benzisoselenazol-3(2H)-one, 2-[3-(trifluoromethyl)phenyl]- | 2570461-66-2 | 99.4% | 342.17 g·mol⁻¹ | C14H8F3NOSe | 5 MG
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SARS-CoV-2-IN-7 is a small-molecule inhibitor that reduces SARS-CoV-2 replication in vitro, with a reported IC50 of 844 nM in infected Vero E6 cells. It is supplied for research use and is available as a solid or as DMSO solution in multiple package sizes.
- Demonstrated antiviral activity in cell culture (IC50 844 nM).
- High reported chemical purity (99.4%).
- Available as solid (mg quantities) and 10 mM DMSO solution formats.
- Molecular weight 342.17 g·mol⁻¹ and formula C14H8F3NOSe.
- Suitable for in vitro assays and mechanistic studies of viral replication.
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Medchemexpress LLC Bay 41-8543 | 256498-66-5 | MFCD18382081 | 99.9% | 420.44 g/mol | C21H21FN8O | 10 MG
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BAY 41-8543 is a nitric oxide-independent, heme-dependent stimulator of soluble guanylyl cyclase (sGC) used as a research compound with vasodilator and antiplatelet activity. It is orally active in animal studies and is used for studies of cardiovascular and vascular biology.
- Cas number: 256498-66-5.
- Chemical formula: C21H21FN8O.
- Molecular weight: 420.44 g/mol.
- Purity: 99.9%.
- Appearance: white to off-white solid.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Solubility: DMF 16.67 mg/mL, ethanol 1 mg/mL, DMSO <1 mg/mL.
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Medchemexpress LLC Tryptamine guanosine carbamate | 1414808-96-0 | 99.8% | 469.45 g·mol⁻¹ | C21H23N7O6 | 5 MG
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Tryptamine guanosine carbamate is a small-molecule research compound that selectively inhibits HINT1 (histidine triad nucleotide-binding protein 1). It has been reported to enhance morphine antinociception while reducing development of tolerance, making it useful for biochemical and pharmacological studies.
- Selective HINT1 inhibitor (Ki = 34 μM; Kd = 3.65 μM).
- Molecular formula C21H23N7O6.
- Molecular weight 469.45 g·mol⁻¹.
- Purity 99.79% (reported).
- Soluble in DMSO.
- Available in small pack sizes, including 5 mg.
- Applications include HINT1 signaling studies and opioid pharmacology research.
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Medchemexpress LLC Nevadensin | 10176-66-6 | MFCD08689947 | 344.32 | 20 MG
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Nevadensin is a natural flavonoid and a selective human carboxylesterase 1 (hCE1) inhibitor. It demonstrates greater selectivity for hCE1 over hCE2.
- Induces apoptosis and DNA damage in cancer cells.
- Possesses anti-inflammatory, anti-tumor, anti-hypertensive, anti-tubercular, antitussive, antioxidant, and anti-microbial activities.
- Inhibits hCE1 with an IC50 of 2.64 μM.
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Medchemexpress LLC Parp-2-in-1 | 2115698-83-2 | 99.6% | 465.40 g·mol⁻¹ | C21H19F4N5O3 | 10 MG
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PARP-2-IN-1 is a potent, selective inhibitor of poly(ADP-ribose) polymerase 2 (PARP-2) used in research on DNA damage response and programmed cell death. It exhibits an IC50 of 11.5 nM against PARP-2 and is supplied as a high-purity small-molecule reagent for laboratory studies.
- Potent and selective PARP-2 inhibition (IC50 11.5 nM).
- High purity suitable for research (>99.5% by HPLC).
- Well-characterized molecular properties (C21H19F4N5O3, 465.40 g·mol⁻¹).
- Available in small mg-scale quantities for laboratory research.
- Suitable for biochemical and cell-based assays studying DNA repair and apoptosis.
- Provided with product datasheet and analytical data.
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Medchemexpress LLC SIRT-IN-2 | 1431411-66-3 | 98.1% | 383.49 | 50 MG
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SIRT-IN-2 is a potent inhibitor of SIRT1/2/3, with IC50s of 4, 4, 7 nM, respectively. It is described as one of the most potent truncated pan SIRT1/2/3 inhibitors. SIRT-IN-2 (compound 31) binds identically in the catalytic active site (RMS=0.29), occupying the nicotinamide C-pocket and acetyl lysine substrate channel.
- Potent inhibitor of SIRT1/2/3
- IC50s of 4, 4, 7 nM for SIRT1, SIRT2, and SIRT3
- Truncated pan SIRT1/2/3 inhibitor
- Binds in the catalytic active site
- Occupies nicotinamide C-pocket and acetyl lysine substrate channel
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Medchemexpress LLC FKBP12 PROTAC RC32 | 2375555-66-9 | 97.0% | 100 MG
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FKBP12 PROTAC RC32 (RC32) is a potent FKBP12 degrader that utilizes PROTAC technology. It is a conjugate of Rapamycin and a ligand for a Cereblon E3 ubiquitin ligase, designed to efficiently degrade FKBP12 protein.
- Potent degrader of FKBP12
- Based on PROTAC technology
- Contains conjugation of Rapamycin and a ligand for a Cereblon E3 ubiquitin ligase
- Efficiently degrades FKBP12 protein in most organs (in vivo studies)
- Induces FKBP12 protein degradation in human Jurkat cells (DC50 ~0.3 nM)
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Medchemexpress LLC Navocaftor | 2159103-66-7 | 99.2% | 416.33 | 10 MG
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Navocaftor is a protein modulator that acts as a cystic fibrosis transmembrane regulator (CFTR). It is intended for research use only. This compound has a high purity and exhibits specific solubility characteristics for various research applications.
- Solid appearance
- Light yellow to yellow color
- Purity of 99.20%
- Stable for 3 years at -20°C as powder
- Soluble in 10% DMSO, 90% corn oil for in vivo studies
- Acts as a cystic fibrosis transmembrane regulator (CFTR) protein modulator
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Medchemexpress LLC Navocaftor | 2159103-66-7 | 99.2% | 416.33 g/mol | C15H11F3N4O5S | 5 MG
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Navocaftor is a small-molecule cystic fibrosis transmembrane conductance regulator (CFTR) potentiator developed for research into restoring or enhancing CFTR channel function. It is supplied as a high-purity research reagent for in vitro and preclinical studies investigating CFTR modulation and combination therapy effects.
- High purity (99.2%).
- Molecular weight 416.3 g/mol.
- Molecular formula C15H11F3N4O5S.
- Intended for research use in CFTR modulation studies.
- Supplied in 5 mg research quantities.
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Medchemexpress LLC N-acetyltyramine | 1202-66-0 | 99.7% | 10 MG
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N-acetyltyramine is the N-acetyl derivative of the biogenic amine tyramine (CAS 1202-66-0). It is supplied for research use and has reported quorum-sensing inhibitory activity; analytical characterization and safety data are available.
- High purity: 99.7%.
- Available as solid packs including 10 mg and as a 10 mM solution in DMSO.
- Comprehensive analytical data available: COA, HPLC, LCMS, and NMR.
- CAS-registered compound for unambiguous identification.
- Intended for research use; consult SDS for handling and safety.
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Medchemexpress LLC Navocaftor | 2159103-66-7 | 99.2% | 416.33 | 100 MG
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Navocaftor (GLPG 3067) is a cystic fibrosis transmembrane regulator (CFTR) and a protein modulator.
- Regulates cystic fibrosis transmembrane conductance.
- Modulates protein function.
- Store powder at -20°C for 3 years or 4°C for 2 years.
- Store in solvent at -80°C for 6 months or -20°C for 1 month.
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Medchemexpress LLC 4-hydroxyatomoxetine | 435293-66-6 | MFCD09840695 | 97.0% | 271.35 | C17H21NO2 | 5 MG
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4-Hydroxyatomoxetine is an active metabolite of atomoxetine used in research on norepinephrine transporter activity and phase I metabolism. It is provided as a small-quantity, high-purity research chemical for in vitro assays, analytical standards, and metabolic studies; follow the supplied safety data and certificate of analysis for handling and storage.
- Active metabolite useful for transporter and metabolism studies.
- High purity (97.0%) for reproducible analytical results.
- Low-quantity packaging suitable for early-stage research.
- Soluble in common organic solvents for assay preparation.
- Certificate of analysis and safety data available from supplier.
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Medchemexpress LLC BODIPY-FL NHS ester | 146616-66-2 | MFCD00467385 | 99.8% | 389.16 g·mol⁻¹ | C18H18BF2N3O4 | 5 MG
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BODIPY-FL NHS ester is an amine-reactive, membrane-permeable fluorescent dye with excitation around 502 nm and emission around 510-511 nm, used to label proteins, peptides, and other primary-amine-containing molecules for research applications. It offers high photostability and maintains fluorescence across a range of solvent polarities and pH conditions.
- Amine-reactive NHS ester for efficient conjugation to primary amines.
- Excitation ~502 nm and emission ~510-511 nm for green fluorescence detection.
- High photostability and stable fluorescence across pH and solvent conditions.
- High purity suitable for labeling, imaging, and assay development.
- Available as a solid in multiple sizes for flexible experimental use.
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